Genetic inactivation of GIP signaling reverses aging-associated insulin resistance through body composition changes

Biochemical and Biophysical Research Communications

Volumn 364, Issue 1, 2007, Pages 175-180

  Yamada, Chizumi ^a   Yamada, Yuichiro ^a,b   Tsukiyama, Katsushi ^a   Yamada, Kotaro ^a   Yamane, Shunsuke ^a   Harada, Norio ^a   Miyawaki, Kazumasa ^c   Seino, Yutaka ^a,d   Inagaki, Nobuya ^a,e  

^a KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b AKITA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c KYOTO UNIVERSITY HOSPITAL   (Japan)

^d KANSAI ELECTRIC POWER CO   (Japan)

^e JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Aging; Body composition; Fat mass; GIP; GIP antagonism; Insulin resistance; Lean mass; Physical activity

Indexed keywords

ADIPONECTIN; GASTRIC INHIBITORY POLYPEPTIDE; INSULIN;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY COMPOSITION; BODY FAT; BODY WEIGHT; CONTROLLED STUDY; DIET; FOOD INTAKE; GENE INACTIVATION; GLUCOSE TOLERANCE; INSULIN RESISTANCE; INSULIN SENSITIVITY; KNOCKOUT MOUSE; LEAN BODY WEIGHT; MALE; MOUSE; NONHUMAN; PHYSICAL ACTIVITY; PRIORITY JOURNAL; WILD TYPE;

ADIPOKINES; ADIPOSE TISSUE; AGING; ANIMALS; BEHAVIOR, ANIMAL; BLOOD GLUCOSE; BODY COMPOSITION; GASTRIC INHIBITORY POLYPEPTIDE; GLUCOSE TOLERANCE TEST; INSULIN RESISTANCE; MALE; MICE; MICE, KNOCKOUT; MOTOR ACTIVITY; SIGNAL TRANSDUCTION;

MUS;

EID: 35348964675     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.09.128     Document Type: Article

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