Impaired PI3K/Akt activation-mediated NF-κB inactivation under elevated TNF-α is more vulnerable to apoptosis in vitiliginous keratinocytes

Journal of Investigative Dermatology

Volumn 127, Issue 11, 2007, Pages 2612-2617

  Kim, Nan Hyung ^a   Jeon, Songhee ^a   Lee, Hyun Joo ^a   Lee, Ai Young ^a  

^a Dongguk University College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; FAS LIGAND; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2; WORTMANNIN;

ADOLESCENT; ADULT; APOPTOSIS; ARTICLE; CHILD; CLINICAL ARTICLE; DEPIGMENTATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; EPIDERMIS; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KERATINOCYTE; MALE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; VITILIGO; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADOLESCENT; ADULT; ANDROSTADIENES; APOPTOSIS; CELLS, CULTURED; CHILD; ENZYME ACTIVATION; FAS LIGAND PROTEIN; FEMALE; HUMANS; I-KAPPA B PROTEINS; KERATINOCYTES; MALE; MIDDLE AGED; NF-KAPPA B; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA; VITILIGO;

EID: 35348923497     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/sj.jid.5700900     Document Type: Article

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