Huntingtin-interacting protein 1 influences worm and mouse presynaptic function and protects Caenorhabditis elegans neurons against mutant polyglutamine toxicity

Journal of Neuroscience

Volumn 27, Issue 41, 2007, Pages 11056-11064

  Parker, J Alex ^a,b   Metzler, Martina ^c   Georgiou, John ^d   Mage, Marilyne ^a,b   Roder, John C ^d,e   Rose, Ann M ^f   Hayden, Michael R ^c   Néri, Christian ^a,b  

^a INSERM   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^d MOUNT SINAI HOSPITAL   (Canada)

^e UNIVERSITY OF TORONTO   (Canada)

^f UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

HIP1; Huntington's disease; Neurodegeneration; Polyglutamine; Synapse; Synaptic plasticity

Indexed keywords

AMINO ACID; CAENORHABDITIS ELEGANS PROTEIN; ENDOPHILIN; HUNTINGTIN; HUNTINGTIN INTERACTING PROTEIN 1; POLYGLUTAMINE; SYNAPSIN I; SYNAPTOBREVIN; SYNAPTOJANIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; DEPRESSION; ENDOCYTOSIS; FACILITATION; HIPPOCAMPUS; HUMAN; MOUSE; MUTANT; NEMATODE; NERVE CELL; NERVE CELL PLASTICITY; NERVE DEGENERATION; NEUROMODULATION; NONHUMAN; PRESYNAPTIC NERVE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INTERACTION; SYNAPSE VESICLE; SYNAPTOSOME; TRANSGENICS; WORM;

ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; DNA-BINDING PROTEINS; EXCITATORY POSTSYNAPTIC POTENTIALS; MICE; MICE, KNOCKOUT; MUTATION; NEURONS; PEPTIDES; PRESYNAPTIC TERMINALS; SYNAPSES;

EID: 35348913211     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1941-07.2007     Document Type: Article

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