Mechanically induced intracellular calcium waves in osteoblasts demonstrate calcium fingerprints in bone cell mechanotransduction

Biomechanics and Modeling in Mechanobiology

Volumn 6, Issue 6, 2007, Pages 391-398

  Godin, Lindsay M ^a   Suzuki, Sakiko ^a   Jacobs, Christopher R ^b   Donahue, Henry J ^c   Donahue, Seth W ^a  

^a Michigan Technological University   (United States)

^b STANFORD UNIVERSITY   (United States)

^c PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMECHANICS; CALCIUM; CONCENTRATION (PROCESS); OSTEOBLASTS;

IDENTICAL BOUTS; INTRACELLULAR CALCIUM; WAVE PARAMETERS;

BONE;

CALCIUM;

ANIMAL; ARTICLE; BONE; CALCIUM SIGNALING; CELL CULTURE; CYTOLOGY; CYTOSOL; MECHANOTRANSDUCTION; METABOLISM; MOUSE; OSTEOBLAST; PHYSIOLOGY; RAT; STATISTICAL MODEL;

ANIMALS; BONE AND BONES; CALCIUM; CALCIUM SIGNALING; CELLS, CULTURED; CYTOSOL; LINEAR MODELS; MECHANOTRANSDUCTION, CELLULAR; MICE; OSTEOBLASTS; RATS;

EID: 35148898089     PISSN: 16177959     EISSN: 16822978     Source Type: Journal    
DOI: 10.1007/s10237-006-0059-5     Document Type: Article

References (43)

1. Ajubi NE, Klein-Nulend J, Alblas MJ, Burger EH, Nijweide PJ (1999) Signal transduction pathways involved in fluid flow-induced pge2 production by cultured osteocytes. Am J Physiol 276:E171-E178
2. Allen FD, Hung CT, Pollack SR, Brighton CT (1996) Comparison of the ca2+ response to fluid flow of mc3tc-e1, ros 17/2.8, and cultured primary osteoblast-like cells to fluid flow. J Cell Eng 1:117-124
3. Andreoli A, Monteleone M, Van Loan M, Promenzio L, Tarantino U, De Lorenzo A (2001) Effects of different sports on bone density and muscle mass in highly trained athletes. Med Sci Sports Exerc 33:507-511
4. Banes AJ, Tsuzaki M, Yamamoto J, Fischer T, Brigman B, Brown T, Miller L (1995) Mechanoreception at the cellular level: the detection, interpretation, and diversity of responses to mechanical signals. Biochem Cell Biol 73:349-365
5. Batra NN, Li YJ, Yellowley CE, You L, Malone AM, Kim CH, Jacobs CR (2005) Effects of short-term recovery periods on fluid-induced signaling in osteoblastic cells. J Biomech 38:1909-1917
6. Berridge MJ (1993) Inositol trisphosphate and calcium signalling. Nature 361:315-325
7. Berridge MJ (1997) The am and fm of calcium signalling. Nature 386:759-760
8. Berridge MJ, Bootman MD, Lipp P (1998) Calcium - a life and death signal. Nature 395:645-648
9. Berridge MJ, Lipp P, Bootman MD (2000) The versatility and universality of calcium signalling. Nat Rev Mol Cell Biol 1:11-21
10. Bloomfield SA (2001) Cellular and molecular mechanisms for the bone response to mechanical loading. Int J Sport Nutr Exerc Metab 11 Suppl:S128-S136
11. Burger EH, Klein-Nulend J (1999) Mechanotransduction in bone - role of the lacuno-canalicular network. Faseb J 13 Suppl:S101-S112
12. Clapham DE (1995) Calcium signaling. Cell 80:259-268
13. Crabtree GR (2001) Calcium, calcineurin, and the control of transcription. J Biol Chem 276:2313-2316
14. De Koninck P, Schulman H (1998) Sensitivity of cam kinase ii to the frequency of ca2+ oscillations. Science 279:227-230
15. Dolmetsch RE, Lewis RS, Goodnow CC, Healy JI (1997) Differential activation of transcription factors induced by ca2+ response amplitude and duration. Nature 386:855-858
16. Dolmetsch RE, Xu K, Lewis RS (1998) Calcium oscillations increase the efficiency and specificity of gene expression. Nature 392:933-936
17. Donahue SW, Jacobs CR, Donahue HJ (2001) Flow-induced calcium oscillations in rat osteoblasts are age, loading frequency, and shear stress dependent. Am J Physiol Cell Physiol 281:C1635-C1641
18. Donahue SW, Donahue HJ, Jacobs CR (2003) Osteoblastic cells have refractory periods for fluid-flow-induced intracellular calcium oscillations for short bouts of flow and display multiple low-magnitude oscillations during long-term flow. J Biomech 36:35-43
19. Duncan RL, Turner CH (1995) Mechanotransduction and the functional response of bone to mechanical strain. Calcif Tissue Int 57:344-358
20. Franceschi RT, Iyer BS (1992) Relationship between collagen synthesis and expression of the osteoblast phenotype in mc3t3-e1 cells. J Bone Miner Res 7:235-246
21. i signaling in intact rat aortic endothelium. Faseb J 14:797-804
22. Hung CT, Pollack SR, Reilly TM, Brighton CT (1995) Real-time calcium response of cultured bone cells to fluid flow. Clin Orthop Relat Res (313):256-269
23. Jacobs CR, Yellowley CE, Davis BR, Zhou Z, Cimbala JM, Donahue HJ (1998) Differential effect of steady versus oscillating flow on bone cells. J Biomech 31:969-976
24. Knothe Tate ML, Knothe U (2000) An ex vivo model to study transport processes and fluid flow in loaded bone. J Biomech 33:247-254
25. Knothe Tate ML, Steck R, Forwood MR, Niederer P (2000) In vivo demonstration of load-induced fluid flow in the rat tibia and its potential implications for processes associated with functional adaptation. J Exp Biol 203:2737-2745
26. Krahl H, Michaelis U, Pieper HG, Quack G, Montag M (1994) Stimulation of bone growth through sports. A radiologic investigation of the upper extremities in professional tennis players. Am J Sports Med 22:751-757
27. Kraus M, Wolf B (1996) Crosstalk between cellular morphology and calcium oscillation patterns. Insights from a stochastic computer model. Cell Calcium 19:461-472
28. Landis WJ, Hodgens KJ, Block D, Toma CD, Gerstenfeld LC (2000) Spaceflight effects on cultured embryonic chick bone cells. J Bone Miner Res 15:1099-1112
29. Lang T, LeBlanc A, Evans H, Lu Y, Genant H, Yu A (2004) Cortical and trabecular bone mineral loss from the spine and hip in long-duration spaceflight. J Bone Miner Res 19:1006-1012
30. Larsson-Nyren G, Pakhtusova N, Sehlin J (2002) Isolated mouse pancreatic beta-cells show cell-specific temporal response pattern. Am J Physiol Cell Physiol 282:C1199-C1204
31. Mitsuyama H, Kambe F, Murakami R, Cao X, Ishiguro N, Seo H (2004) Calcium signaling pathway involving calcineurin regulates interleukin-8 gene expression through activation of nf-kappab in human osteoblast-like cells. J Bone Miner Res 19:671-679
32. Modlesky CM, Slade JM, Bickel CS, Meyer RA, Dudley GA (2005) Deteriorated geometric structure and strength of the midfemur in men with complete spinal cord injury. Bone 36:331-339
33. 2+] responses in glucose-stimulated single and aggregated beta-cells. Cell Calcium 34: 121-129
34. 2+] in carbamylcholine-stimulated insulinoma cells. J Biol Chem 263:11044-11047
35. Robling AG, Burr DB, Turner CH (2000) Partitioning a daily mechanical stimulus into discrete loading bouts improves the osteogenic response to loading. J Bone Miner Res 15:1596-1602
36. Robling AG, Burr DB, Turner CH (2001) Recovery periods restore mechanosensitivity to dynamically loaded bone. J Exp Biol 204:3389-3399
37. Robling AG, Hinant FM, Burr DB, Turner CH (2002a) Improved bone structure and strength after long-term mechanical loading is greatest if loading is separated into short bouts. J Bone Miner Res 17:1545-1554
38. Robling AG, Hinant FM, Burr DB, Turner CH (2002b) Shorter, more frequent mechanical loading sessions enhance bone mass. Med Sci Sports Exerc 34:196-202
39. Soderling TR, Chang B, Brickey D (2001) Cellular signaling through multifunctional ca2+/calmodulin-dependent protein kinase ii. J Biol Chem 276:3719-3722
40. Takahashi A, Camacho P, Lechleiter JD, Herman B (1999) Measurement of intracellular calcium. Physiol Rev 79: 1089-1125
41. 2+] signaling: mechanisms and physiological roles. Am J Physiol 269:G173-G185
42. Weinbaum S, Cowin SC, Zeng Y (1994) A model for the excitation of osteocytes by mechanical loading-induced bone fluid shear stresses. J Biomech 27:339-360
43. You J, Reilly GC, Zhen X, Yellowley CE, Chen Q, Donahue HJ, Jacobs CR (2001) Osteopontin gene regulation by oscillatory fluid flow via intracellular calcium mobilization and activation of mitogen-activated protein kinase in mc3t3-e1 osteoblasts. J Biol Chem 276:13365-13371