AF10-dependent transcription is enhanced by its interaction with FLRG

Biology of the Cell

Volumn 99, Issue 10, 2007, Pages 563-571

  Forissier, Stéphanie ^a,b,c   Razanajaona, Diane ^a,b,c   Ay, Anne Sophie ^a,b,c   Martel, Sylvie ^a,b,c   Bartholin, Laurent ^a,b,c   Rimokh, Ruth ^a,b,c  

^a INSERM   (France)

^b CENTRE LÉON BÉRARD   (France)

^c UNIVERSITÉ LYON 1   (France)

Author keywords

ALL1 (acute lymphoblastic leukaemia) fused gene from chromosome 10 (AF10); Follistatin related gene (FLRG); Leucine zipper domain; Plant homeodomain (PHD); Transcription

Indexed keywords

FOLLISTATIN RELATED PROTEIN; GLYCOPROTEIN; MIXED LINEAGE LEUKEMIA PROTEIN; ONCOPROTEIN; PROTEIN AF10; TRANSACTIVATOR PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; HUMAN; HUMAN CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; OLIGOMERIZATION; ONCOGENE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN TRANSPORT; TRANSCRIPTION REGULATION;

ANIMALS; CELL NUCLEUS; CERCOPITHECUS AETHIOPS; COS CELLS; FOLLISTATIN-RELATED PROTEINS; GENES, REPORTER; HELA CELLS; HUMANS; PROTEIN ISOFORMS; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TWO-HYBRID SYSTEM TECHNIQUES;

EID: 35148844196     PISSN: 02484900     EISSN: None     Source Type: Journal    
DOI: 10.1042/BC20060131     Document Type: Article

References (25)

1. Bartholin, L., Maguer-Satta, V., Hayette, S., Martel, S., Gadoux, M., Bertrand, S., Corbo, L., Lamadon, C., Morera, A. M., Magaud, J. P. and Rimokh, R. (2001) FLRG, an activin-binding protein, is a new target of TGF β transcription activation through Smad proteins. Oncogene 20, 5409-5419
2. Bartholin, L., Maguer-Satta, V., Hayette, S., Martel, S., Gadoux, M., Corbo, L., Magaud, J. P. and Rimokh, R. (2002) Transcription activation of FLRG and follistatin by activin A, through Smad proteins, participates in a negative feedback loop to modulate activin A function. Oncogene 21, 2227-2235
3. Bartholin, L., Destaing, O., Forissier, S., Martel, S., Maguer-Satta, V., Jurdic, P. and Rimokh, R. (2005) FLRG, a new ADAM12-associated protein, modulates osteoclast differentiation. Biol. Cell 97, 577-588
4. Bienz, M. (2006) The PHD finger, a nuclear protein-interaction domain. Trends Biochem. Sci. 31, 35-40
5. Chaplin, T., Ayton, P., Bernard, O. A., Saha, V., Della, V., Hillion, J., Gregorini, A., Lillington, D., Berger, R. and Young, B.D. (1995) A novel class of zinc finger/leucine zipper genes identified from the molecular cloning of the t(10;11) translocation in acute leukemia. Blood 85, 1435-1441
6. Daser, A. and Rabbitts, T. H. (2004) Extending the repertoire of the mixed-lineage leukemia gene MLL in leukemogenesis. Genes Dev. 18, 965-974
7. Debermadi, S., Bassini, A., Jones, L. K., Chaplin, T., Linder, B., de Bruijn, D. R., Meese, E. and Young, B. D. (2002) The MLL fusion partner AF10 binds GAS41, a protein that interacts with the human SWI/SNF complex. Blood 99, 275-281
8. DiMartino, J. F., Ayton, P. M., Chen, E. H., Naftzger, C. C., Young, B. D. and Cleary, M. L. (2002) The AF10 leucine zipper is required for leukemic transformation of myeloid progenitors by MLL-AF10. Blood 99, 3780-3785
9. Florio, P., Ciarmela, P., Toti, P., Maguer-Satta, V., Rimokh, R., Buonocore, G., Rossi, M., Gioffre, W. and Petraglia, F. (2004) Human endometrium and decidua express follistatin-related gene (FLRG) mRNA and peptide. Mol. Cell. Endocrinol. 218, 129-135
10. Harrison, C. A., Gray, R C., Vale, W. W. and Robertson, D. M. (2005) Antagonists of activin signaling: mechanisms and potential biological applications. Trends Endocrinol. Metab. 16, 73-78
11. Hayette, S., Gadoux, M., Martel, S., Bertrand, S., Tigaud, I., Magaud, J. P. and Rimokh, R. (1998) FLRG (follistatin-related gene), a new target of chromosomal rearrangement in malignant blood disorders. Oncogene 16, 2949-2954
12. Henderson, J. E. (1997) Nuclear targeting of secretory proteins. Mol. Cell. Endocrinol. 129, 1-5
13. Hill, J. J., Davies, M. V., Pearson, A. A., Wang, J. H., Hewick, R. M., Wolfman, N. M. and Qiu, Y. (2002) The myostatin propeptide and the follistatin-related gene are inhibitory binding proteins of myostatin in normal serum. J. Biol. Chem. 277, 40735-40741
14. Linder, B., Newman, R., Jones, L. K., Debernardi, S., Young, B. D., Freemont, P., Verrijzer, C. P. and Saha, V. (2000) Biochemical analyses of the AF10 protein: the extended LAP/PHD-finger mediates oligomerisation. J. Mol. Biol. 299, 369-378
15. Maguer-Satta, V. and Rimokh, R. (2004) FLRG, member of the follistatin family, a new player in hematopoiesis. Mol. Cell. Endocrinol. 225, 109-118
16. Maguer-Satta, V., Bartholin, L., Jeanpierre, S., Ffrench, M., Martel, S., Magaud, J. P. and Rimokh, R. (2003) Regulation of human erythropoiesis by activin A, BMP2, and BMP4, members of the TGF β family. Exp. Cell Res. 282, 110-120
17. Maguer-Satta, V., Forissier, S., Bartholin, L., Martel, S., Jeanpierre, S., Bachelard, E. and Rimokh, R. (2006) A novel role for fibronectin type I domain in the regulation of human hematopoietic cell adhesiveness through binding to follistatin domains of FLRG and follistatin. Exp. Cell Res. 312, 434-442
18. Okada, Y., Feng, Q., Lin, Y., Jiang, Q., Li, Y., Coffield, V. M., Su, L., Xu, G. and Zhang, Y. (2005) hDOT1L links histone methylation to leukemogenesis. Cell 121, 167-178
19. Saito, S., Sidis, Y., Mukherjee, A., Xia, Y. and Schneyer, A. (2005) Differential biosynthesis and intracellular transport of follistatin isoforms and follistatin-like-3. Endocrinology 146, 5052-5062
20. Sidis, Y., Schneyer, A. L. and Keutmann, H. T (2005) Heparin and activin-binding determinants in follistatin and FSTL3. Endocrinology 146, 130-136
21. Tortoriello, D. V., Sidis, Y., Holtzman, D. A., Holmes, W. E. and Schneyer, A. L. (2001) Human follistatin-related protein: a structural homologue of follistatin with nuclear localization. Endocrinology 142, 3426-3434
22. Touriol, C., Bornes, S., Bonnal, S., Audigier, S., Prats, H., Prats, A. C. and Vagner, S. (2003) Generation of protein isoform diversity by alternative initiation of translation at non-AUG codons. Biol. Cell 95, 169-178
23. Tsuchida, K., Arai, K. Y., Kuramoto, Y., Yamakawa, N., Hasegawa, Y. and Sugino, H. (2000) Identification and characterization of a novel follistatin-like protein as a binding protein for the TGF-β family. J. Biol. Chem. 275, 40788-40796
24. Wang, H. Q., Takebayashi, K., Tsuchida, K., Nishimura, M. and Noda, Y. (2003) Follistatin-related gene (FLRG) expression in human endometrium: sex steroid hormones regulate the expression of FLRG in cultured human endometrial stromal cells. J. Clin. Endocrinol. Metab. 88, 4432-4439
25. Xia, Y., Sidis, Y. and Schneyer, A. (2004) Overexpression of follistatin-like 3 in gonads causes defects in gonadal development and function in transgenic mice. Mol. Endocrinol. 18, 979-994