Human endometrium and decidua express follistatin-related gene (FLRG) mRNA and peptide

Molecular and Cellular Endocrinology

Volumn 218, Issue 1-2, 2004, Pages 129-135

  Florio, Pasquale ^a   Ciarmela, Pasquapina ^a   Toti, Paolo ^a   Maguer Satta, Veronique ^b   Rimokh, Ruth ^b   Buonocore, Giuseppe ^a   Rossi, Marco ^a   Gioffrè, Walter ^a   Petraglia, Felice ^a  

^a UNIVERSITY OF SIENA   (Italy)

^b CENTRE LÉON BÉRARD   (France)

Author keywords

Activin A; Decidua; Endometrium; Endothelium; Follistatin; Implantation

Indexed keywords

ACTIVIN A; FOLLISTATIN RELATED PROTEIN; MESSENGER RNA;

ADULT; ARTICLE; BLOOD VESSEL WALL; CELL NUCLEUS; CONTROLLED STUDY; CYTOPLASM; ENDOMETRIUM; EPITHELIUM CELL; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOLOCALIZATION; MENSTRUAL CYCLE; PREGNANCY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SAMPLE; STATISTICAL SIGNIFICANCE; STROMA CELL; VASCULAR ENDOTHELIUM;

ACTIVINS; ADULT; ANIMALS; DECIDUA; ENDOMETRIUM; FEMALE; FOLLISTATIN-RELATED PROTEINS; HUMANS; INHIBIN-BETA SUBUNITS; PEPTIDES; PREGNANCY; RNA, MESSENGER;

EID: 2342524658     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mce.2003.12.019     Document Type: Article

References (23)

1. Altschul S.F., Madden T.L., Schaffer A.A., Zhang J., Zhang Z., Miller W. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res. 25:1997;3389-3402
2. Blauer M., Husgafvel S., Syvala H., Tuohimaa P., Ylikomi T. Identification of a nuclear localization signal in activin/inhibin βA subunit intranuclear ßA in rat spermatogenic cells. Biol. Reprod. 60:1999;588-593
3. Caniggia I., Lye S.J., Cross J.C. Activin is a local regulator of human cytotrophoblast cell differentiation. Endocrinology. 138:1997;3976-3986
4. Ciarmela P., Florio P., Toti P., Franchini A., Maguer-Satta V., Ginanneschi G., Ottavini E., Petraglia F. Human placenta and fetal membranes express follistatin-related gene (FLRG) mRNA and protein. J. Endocrinol. Invest. 26:2003;641-645
5. Fazleabas A.T., Strakova Z. Endometrial function: cell specific changes in the uterine environment. Mol. Cell. Endocrinol. 186:2002;143-147. (Review)
6. Florio P., Luisi S., Vigano P., Busacca M., Fadalti M., Genazzani A.R. Healthy women and patients with endometriosis show high concentrations of inhibin A, inhibin B, and Activin-A in peritoneal fluid throughout the menstrual cycle. Hum. Reprod. 13:1998;2606-2611
7. Florio P., Severi F.M., Luisi S., Ciarmela P., Calonaci G., Petraglia F. Endometrial expression and secretion of Activin-A, but not follistatin, increase in the secretory phase of the menstrual cycle. J. Soc. Gynecol. Invest. 10:2003;237-243
8. He Z.Y., Liu H.C., Mele C.A., Barmat L., Veeck L.L., Davis O. Expression of inhibin/activin subunits and their receptors and binding proteins in human preimplantation embryos. J. Assist. Reprod. Genet. 16:1999;73-80
9. Jones R.L., Salamonsen L.A., Critchley H.O., Rogers P.A., Affandi B., Findlay J.K. Inhibin and activin subunits are differentially expressed in endometrial cells and leukocytes during the menstrual cycle, in early pregnancy and in women using progestin-only contraception. Mol. Hum. Reprod. 6:2000;1107-1117
10. Jones R.L., Salamonsen L.A., Findlay J.K. Activin-A promotes human endometrial stromal cell decidualization in vitro. J. Clin. Endocrinol. Metab. 87:2002a;4001-4004
11. Jones R.L., Salamonsen L.A., Zhao Y.C., Ethier J.F., Drummond A.E., Findlay J.K. Expression of activin receptors, follistatin and betaglycan by human endometrial stromal cells consistent with a role for activins during decidualization. Mol. Hum. Reprod. 8:2002b;363-374
12. Kozian D.H., Ziche M., Augustin H.G. The activin-binding protein follistatin regulates autocrine endothelial cell activity and induces angiogenesis. Lab. Invest. 76:1997;267-276
13. Leung P.H., Salamonsen L.A., Findlay J.K. Immunolocalization of inhibin and activin subunits in human endometrium across the menstrual cycle. Hum. Reprod. 13:1998;3469-3477
14. Luisi S., Florio P., Reis F.M., Petraglia F. Expression and secretion of Activin-A: possible physiological and clinical implications. Eur. J. Endocrinol. 145:2001;225-236
15. Maguer-Satta V., Bartholin L., Jeanpierre S., Gadoux M., Bertrand S., Martel S. Expression of FLRG, a novel Activin-A ligand, is regulated by TGF-beta and during hematopoiesis. Exp. Hematol. 29:2001;301-308
16. Noyes R.W., Hertig A.T., Rock J. Dating the endometrial biopsy. Am. J. Obstet. Gynecol. 122:1975;262-263
17. Petraglia F., Florio P., Luisi S., Gallo R., Gadducci A., Vigano P. Expression and secretion of inhibin and activin in normal and neoplastic uterine tissues. High levels of serum Activin-A in women with endometrial and cervical carcinoma. J. Clin. Endocrinol. Metab. 83:1998;1194-1200
18. Reis F.M., Di Blasio A.M., Florio P., Ambrosini G., Di Loreto C., Petraglia F. Evidence for local production of inhibin A and Activin-A in patients with ovarian endometriosis. Fertil. Steril. 75:2001;367-373
19. Schneider-Kolsky M., Manuelpillai U., Gargett C., Wallace E.M. Activin betaA-subunit and activin receptors in human myometrium at term and during labour. Br. J. Obstet. Gynecol. 108:2001;869-874
20. Schneider-Kolsky M.E., Manuelpillai U., Waldron K., Dole A., Wallace E.M. The distribution of Activin-And activin receptors in gestational tissues across human pregnancy and during labour. Placenta. 23:2002;294-302
21. Sidis Y., Tortoriello D.V., Holmes W.E., Pan Y., Keutmann H.T., Schneyer A.L. Follistatin-related protein and follistatin differentially neutralize endogenous vs. exogenous activin. Endocrinology. 143:2002;1613-1624
22. Tortoriello D.V., Sidis Y., Holtzman D.A., Holmes W.E., Schneyer A.L. Human follistatin-related protein: a structural homologue of follistatin with nuclear localization. Endocrinology. 142:2001;3426-3434
23. Vigano P., Somigliana E., Mangioni S., Vignali M., Vignali M., Di Blasio A.M. Expression of interleukin-10 and its receptor is up-regulated in early pregnant versus cycling human endometrium. J. Clin. Endocrinol. Metab. 87:2002;5730-5736