Stage-dependent expression of Pax6 in optic vesicle/cup regulates patterning genes through signaling molecules

Differentiation

Volumn 75, Issue 8, 2007, Pages 726-736

  Reza, Hasan Mahmud ^a   Takahashi, Yoshiko ^a   Yasuda, Kunio ^a  

^a NARA INSTITUTE OF SCIENCE AND TECHNOLOGY   (Japan)

Author keywords

BMP4; Dorso ventral axis formation; Electroporation; Eye development; FGF8; Optic cup formation; Pax6; Signaling pathway; Tbx5; Vax

Indexed keywords

BONE MORPHOGENETIC PROTEIN 4; FIBROBLAST GROWTH FACTOR; TRANSCRIPTION FACTOR PAX6; TRANSCRIPTION FACTOR TBX5;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CHICK EMBRYO; CONTROLLED STUDY; DOWN REGULATION; ELECTROPORATION; EMBRYO; GENE CONTROL; NONHUMAN; OPTIC DISK CUP; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

SPONDIAS PURPUREA;

EID: 35148837607     PISSN: 03014681     EISSN: 14320436     Source Type: Journal    
DOI: 10.1111/j.1432-0436.2007.00168.x     Document Type: Article

References (38)

1. Ashery-Padan, R. Gruss, P. (2001) Pax6 lights-up the way for eye development. Curr Opin Cell Biol 13 : 706 714.
2. Baumer, N., Marquardt, T., Stoykova, A., Ashery-Padan, R., Chowdhury, K. Gruss, P. (2002) Pax6 is required for establishing naso-temporal and dorsal characteristics of the optic vesicle. Development 129 : 4535 4545.
3. Canto-Soler, M.V. Adler, R. (2006) Optic cup and lens development requires Pax6 expression in the early optic vesicle during a narrow time window. Dev Biol 294 : 119 132.
4. Cvekl, A., Yang, Y., Chauhan, B.K. Cveklova, K. (2004) Regulation of gene expression by Pax6 in ocular cells: a case of tissue-preferred expression of crystallins in lens. Int J Dev Biol 48 : 829 844.
5. Duncan, M.K., Kozmik, Z., Cveklova, K., Piatigorsky, J. Cvekl, A. (2000) Overexpression of PAX6(5a) in lens fiber cells results in cataract and upregulation of (alpha)5(beta)1 integrin expression. J Cell Sci 113 : 3173 3185.
6. Fujiwara, M., Uchida, T., Osumi-Yamashita, N. Eto, K. (1994) Uchida rat (rSey): a new mutant rat with craniofacial abnormalities resembling those of the mouse Sey mutant. Differentiation 57 : 31 38.
7. Furthauer, M., Van Celst, J., Thisse, C. Thisse, B. (2004) Fgf signalling controls the dorsoventral patterning of the zebrafish embryo. Development 131 : 2853 2864.
8. Furuta, Y. Hogan, B.L.M. (1998) BMP4 is essential for lens induction in the mouse embryo. Genes Dev 12 : 3764 3775.
9. Glaser, T., Jepeal, L., Edwards, J.G., Young, S.R., Favor, J. Maas, R.L. (1994) PAX6 gene dosage effect in a family with congenital cataracts, aniridia, anophthalmia and central nervous system defects. Nat Genet 7 : 463 471.
10. Hamburger, V. Hamilton, H.L. (1951) A series of normal stages in the development of the chick embryo. J Morphol 88 : 49 92.
11. Hanson, I. Van Heyningen, V. (1995) Pax6: more than meets the eye. Trends Genet 11 : 268 272.
12. Henrique, D., Adam, J., Myat, A., Chitnis, A., Lewis, J. Ish-Horowicz, D. (1995) Expression of a delta homologue in prospective neurons in the chick [see comments]. Nature 375 : 787 790.
13. Hill, R.E., Favor, J., Hogan, B.L., Ton, C.C., Saunders, G.F., Hanson, I.M., Prosser, J., Jordan, T., Hastie, N.D. van Heyningen, V. (1991) Mouse small eye results from mutations in a paired-like homeobox- containing gene [published erratum appears in Nature 1992 Feb 20;355(6362):750]. Nature 354 : 522 525.
14. Hogan, B.L., Horsburgh, G., Cohen, J., Hetherington, C.M., Fisher, G. Lyon, M.F. (1986) Small eyes (Sey): a homozygous lethal mutation on chromosome 2 which affects the differentiation of both lens and nasal placodes in the mouse. J Embryol Exp Morphol 97 : 95 110.
15. Hyer, J., Kuhlman, J., Afif, E. Mikawa, T. (2003) Optic cup morphogenesis requires pre-lens ectoderm but not lens differentiation. Dev Biol 259 : 351 363.
16. Kondoh, H. (1999) Transcription factors for lens development assessed in vivo. Curr Opin Genet Dev 9 : 301 308.
17. Koshiba-Takeuchi, K., Takeuchi, J.K., Matsumoto, K., Momose, T., Uno, K., Hoepker, V., Ogura, K., Takahashi, N., Nakamura, H., Yasuda, K. Ogura, T. (2000) Tbx5 and the retinotectum projection. Science 287 : 134 137.
18. Lang, R.A. (2004) Pathways regulating lens induction in the mouse. Int J Dev Biol 48 : 783 791.
19. Leconte, L., Lecoin, L., Martin, P. Saule, S. (2004) Pax6 interacts with cVax and Tbx5 to establish the dorsoventral boundary of the developing eye. J Biol Chem 279 : 47272 47277.
20. Lovicu, F.J. McAvoy, J.W. (2005) Growth factor regulation of lens development. Dev Biol 280 : 1 14.
21. Matsuo, T., Osumi-Yamashita, N., Noji, S., Ohuchi, H., Koyama, E., Myokai, F., Matsuo, N., Taniguchi, S., Doi, H. Iseki, S., et al 1993) A mutation in the Pax-6 gene in rat small eye is associated with impaired migration of midbrain crest cells. Nat Genet 3 : 299 304.
22. Mui, S.H., Kim, J.W., Lemke, G. Bertuzzi, S. (2005) Vax genes ventralize the embryonic eye. Genes Dev 19 : 1249 1259.
23. Niswander, L. Martin, G.R. (1993) FGF-4 and BMP-2 have opposite effects on limb growth. Nature 361 : 68 71.
24. Ogino, H. Yasuda, K. (1998) Induction of lens differentiation by activation of a bZIP transcription factor, L-Maf. Science 280 : 115 118.
25. Ohkubo, Y., Chiang, C. Rubenstein, J.L. (2002) Coordinate regulation and synergistic actions of BMP4, SHH and FGF8 in the rostral prosencephalon regulate morphogenesis of the telencephalic and optic vesicles. Neuroscience 111 : 1 17.
26. Pera, E.M., Ikeda, A., Eivers, E. De Robertis, E.M. (2003) Integration of IGF, FGF, and anti-BMP signals via Smad1 phosphorylation in neural induction. Genes Dev 17 : 3023 3028.
27. Prosser, J. van Heyningen, V. (1998) PAX6 mutations reviewed. Hum Mutat 11 : 93 108.
28. Reza, H.M., Ogino, H. Yasuda, K. (2002) L-Maf, a downstream target of Pax6, is essential for chick lens development. Mech Dev 116 : 61 73.
29. Reza, H.M. Yasuda, K. (2004a) The involvement of neural retina pax6 in lens fiber differentiation. Dev Neurosci 26 : 318 327.
30. Reza, H.M. Yasuda, K. (2004b) Lens differentiation and crystallin regulation: a chick model. Int J Dev Biol 48 : 805 817.
31. Sato, T., Araki, I. Nakamura, H. (2001) Inductive signal and tissue responsiveness defining the tectum and the cerebellum. Development 128 : 2461 2469.
32. Schedl, A., Ross, A., Lee, M., Engelkamp, D., Rashbass, P., van Heyningen, V. Hastie, N.D. (1996) Influence of PAX6 gene dosage on development: overexpression causes severe eye abnormalities. Cell 86 : 71 82.
33. Thesleff, I. Mikkola, M. (2002) The role of growth factors in tooth development. Int Rev Cytol 217 : 93 135.
34. Trousse, F., Esteve, P. Bovolenta, P. (2001) Bmp4 mediates apoptotic cell death in the developing chick eye. J Neurosci 21 : 1292 1301.
35. Vogel-Hopker, A., Momose, T., Rohrer, H., Yasuda, K., Ishihara, L. Rapaport, D.H. (2000) Multiple functions of fibroblast growth factor-8 (FGF-8) in chick eye development. Mech Dev 94 : 25 36.
36. Warren, S.M., Brunet, L.J., Harland, R.M., Economides, A.N. Longaker, M.T. (2003) The BMP antagonist noggin regulates cranial suture fusion. Nature 422 : 625 629.
37. Weaver, M., Dunn, N.R. Hogan, B.L. (2000) Bmp4 and Fgf10 play opposing roles during lung bud morphogenesis. Development 127 : 2695 2704.
38. Wilson, S.I., Graziano, E., Harland, R., Jessell, T.M. Edlund, T. (2000) An early requirement for FGF signalling in the acquisition of neural cell fate in the chick embryo. Curr Biol 10 : 421 429.