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Volumn 9, Issue 3, 1999, Pages 301-308

Transcription factors for lens development assessed in vivo

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN SOX; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

EID: 0033152657     PISSN: 0959437X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-437X(99)80045-8     Document Type: Article
Times cited : (58)

References (71)
  • 1
    • 0002084526 scopus 로고
    • Ueber correlationen in der entwickelung des auges
    • Title translation: On interactions during eye development
    • Spemann H: Ueber correlationen in der entwickelung des auges. Verhandl Anat Ges 1901, 15:61-79. [Title translation: On interactions during eye development.]
    • (1901) Verhandl Anat Ges , vol.15 , pp. 61-79
    • Spemann, H.1
  • 2
    • 0026800666 scopus 로고
    • Embryonic lens induction: Shedding light on vertebrate tissue determination
    • Grainger RM: Embryonic lens induction: Shedding light on vertebrate tissue determination. Trends Genet 1992, 8:349-355.
    • (1992) Trends Genet , vol.8 , pp. 349-355
    • Grainger, R.M.1
  • 3
    • 0000072876 scopus 로고    scopus 로고
    • New perspectives on embryonic lens induction
    • Grainger RM: New perspectives on embryonic lens induction. Semin Cell Dev Biol 1997, 7:149-155.
    • (1997) Semin Cell Dev Biol , vol.7 , pp. 149-155
    • Grainger, R.M.1
  • 4
    • 0031001710 scopus 로고    scopus 로고
    • The Rx homeobox gene is essential for vertebrate eye development
    • Mathers PH, Grinberg A, Mahorn KA, Jamrich M: The Rx homeobox gene is essential for vertebrate eye development. Nature 1997, 387:603-607.
    • (1997) Nature , vol.387 , pp. 603-607
    • Mathers, P.H.1    Grinberg, A.2    Mahorn, K.A.3    Jamrich, M.4
  • 5
    • 0003143704 scopus 로고
    • Cytological aspects of embryonic lens induction in the chick
    • McKeehan MS: Cytological aspects of embryonic lens induction in the chick. J Ex Zool 1951, 117:31-64.
    • (1951) J Ex Zool , vol.117 , pp. 31-64
    • McKeehan, M.S.1
  • 6
    • 0014848872 scopus 로고    scopus 로고
    • The prenatal development of the mouse eye
    • Pei YF, Rhodin JAG: The prenatal development of the mouse eye. Anat Rec 970, 168:105-126.
    • Anat Rec 970 , vol.168 , pp. 105-126
    • Pei, Y.F.1    Rhodin, J.A.G.2
  • 7
    • 0024458628 scopus 로고
    • Fibroblast growth factor (FGF) induces different responses in lens epithelial cells depending on its concentration
    • McAvoy JW, Chamberlain CG: Fibroblast growth factor (FGF) induces different responses in lens epithelial cells depending on its concentration. Development 1989, 107:221-228.
    • (1989) Development , vol.107 , pp. 221-228
    • McAvoy, J.W.1    Chamberlain, C.G.2
  • 8
    • 0031595782 scopus 로고    scopus 로고
    • Overlapping effects of different members of the FGF family on lens fiber differentiation in transgenic mice
    • Lovicu FJ, Overbeek PA: Overlapping effects of different members of the FGF family on lens fiber differentiation in transgenic mice. Development 1998, 125:3365-3377.
    • (1998) Development , vol.125 , pp. 3365-3377
    • Lovicu, F.J.1    Overbeek, P.A.2
  • 9
    • 0141632494 scopus 로고
    • Lentropin, a protein that controls lens fiber formation, is related functionally and immunologically to the insulin-like growth factors
    • Beebe DC, Silver MH, Blecker KS, van Wyk JJ, Svoboda ME, Zelenka PS: Lentropin, a protein that controls lens fiber formation, is related functionally and immunologically to the insulin-like growth factors. Proc Natl Acad Sci USA 1987, 84:2327-2330.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 2327-2330
    • Beebe, D.C.1    Silver, M.H.2    Blecker, K.S.3    Van Wyk, J.J.4    Svoboda, M.E.5    Zelenka, P.S.6
  • 10
    • 0019786296 scopus 로고
    • Lens differentiation in vertebrates
    • Piatigorsky J: Lens differentiation in vertebrates. Differentiation 1981, 19:134-153.
    • (1981) Differentiation , vol.19 , pp. 134-153
    • Piatigorsky, J.1
  • 11
    • 0022621979 scopus 로고
    • Expression of N-cadherin adhesion molecules associated with early morphogenetic events in chick development
    • Hatta K, Takeichi M: Expression of N-cadherin adhesion molecules associated with early morphogenetic events in chick development. Nature 1986, 320:447-449.
    • (1986) Nature , vol.320 , pp. 447-449
    • Hatta, K.1    Takeichi, M.2
  • 12
    • 0028905818 scopus 로고
    • Vimentin and CP49/filensin form distinct networks in the lens which are independently modulated during lens fibre cell differentiation
    • Sandilands A, Prescott AR, Carter JM, Hutcheson AM, Quinlan RA, Richards J, FitzGerald PG: Vimentin and CP49/filensin form distinct networks in the lens which are independently modulated during lens fibre cell differentiation. J Cell Sci 1995, 108:1397-1406.
    • (1995) J Cell Sci , vol.108 , pp. 1397-1406
    • Sandilands, A.1    Prescott, A.R.2    Carter, J.M.3    Hutcheson, A.M.4    Quinlan, R.A.5    Richards, J.6    FitzGerald, P.G.7
  • 14
    • 0032532490 scopus 로고    scopus 로고
    • KIP2 in the control of tissue growth and development
    • KIP2 are involved in cell-cycle withdrawal during transition from lens epithelium to lens fibers. Loss of these CKIs in the lens results in persisitent DNA synthesis, increased apoptosis and perturbation of the cell maturation in the fiber compartment.
    • (1998) Genes Dev , vol.12 , pp. 3162-3167
    • Zhang, P.1    Wong, C.2    DePinho, R.A.3    Harper, J.W.4    Elledge, S.J.5
  • 15
    • 0022558958 scopus 로고
    • Small eyes (Sey): A homozygous lethal mutation on chromosome 2 which affects the differentiation of both lens and nasal placodes in the mouse
    • Hogan BLM, Horsburgh G, Cohen J, Hetherington CM, Fisher G, Lyon MF: Small eyes (Sey): A homozygous lethal mutation on chromosome 2 which affects the differentiation of both lens and nasal placodes in the mouse. J Embryol Exp Morphol 1986, 97:95-110.
    • (1986) J Embryol Exp Morphol , vol.97 , pp. 95-110
    • Hogan, B.L.M.1    Horsburgh, G.2    Cohen, J.3    Hetherington, C.M.4    Fisher, G.5    Lyon, M.F.6
  • 20
    • 0028074973 scopus 로고
    • PAX6 gene dosage effect in a family with congenital cataracts, aniridia, anophthalmia and central nervous system defects
    • Glaser T, JepeaL L, Edwards JG, Young SR, Favor J, Maas RL: PAX6 gene dosage effect in a family with congenital cataracts, aniridia, anophthalmia and central nervous system defects. Nat Genet 1994, 7:463-471.
    • (1994) Nat Genet , vol.7 , pp. 463-471
    • Glaser, T.1    Jepeal, L.2    Edwards, J.G.3    Young, S.R.4    Favor, J.5    Maas, R.L.6
  • 21
    • 0028918392 scopus 로고
    • DNA-binding and transactivation properties of Pax-6: Three amino acids in the paired domain are responsible for the different sequence recognition of Pax-6 and BSAP
    • Czerny T, Busslinger M: DNA-binding and transactivation properties of Pax-6: Three amino acids in the paired domain are responsible for the different sequence recognition of Pax-6 and BSAP. Mol Cell Biol 1995, 15:2858-2871.
    • (1995) Mol Cell Biol , vol.15 , pp. 2858-2871
    • Czerny, T.1    Busslinger, M.2
  • 22
    • 0026340588 scopus 로고
    • Pax-6, a murine paired box gene, is expressed in the developing CNS
    • Walther C, Gruss P: Pax-6, a murine paired box gene, is expressed in the developing CNS. Development 1991, 13:1435-1449.
    • (1991) Development , vol.13 , pp. 1435-1449
    • Walther, C.1    Gruss, P.2
  • 23
    • 0026949405 scopus 로고
    • Genomic structure, evolutionary conservation and aniridia mutations in the human pax-6 gene
    • Glaser T, Waldon D, Maas RL: Genomic structure, evolutionary conservation and aniridia mutations in the human pax-6 gene. Nat Genet 1992, 2:231 -239.
    • (1992) Nat Genet , vol.2 , pp. 231-239
    • Glaser, T.1    Waldon, D.2    Maas, R.L.3
  • 24
    • 0028096639 scopus 로고
    • Two independent and interactive DNA-binding subdomains of the Pax6 paired domain are regulated by alternative splicing
    • Epstein JA, Glaser T, Cai J, JepeaL L, Walton DS, Maas RL: Two independent and interactive DNA-binding subdomains of the Pax6 paired domain are regulated by alternative splicing. Genes Dev 1994, 8:2022-2034.
    • (1994) Genes Dev , vol.8 , pp. 2022-2034
    • Epstein, J.A.1    Glaser, T.2    Cai, J.3    Jepeal, L.4    Walton, D.S.5    Maas, R.L.6
  • 25
    • 0030832612 scopus 로고    scopus 로고
    • Alternatively spliced insertions in the paired domain restrict the DNA sequence specificity of Pax6 and Pax8
    • Kozmik Z, Czerny T, Busslinger M: Alternatively spliced insertions in the paired domain restrict the DNA sequence specificity of Pax6 and Pax8. EMBO J 1997, 16:6793-6803.
    • (1997) EMBO J , vol.16 , pp. 6793-6803
    • Kozmik, Z.1    Czerny, T.2    Busslinger, M.3
  • 26
    • 0027965633 scopus 로고
    • Homology of the eyeless gene of Drosophila to the Small eye gene in mice and Aniridia in humans
    • Quiring R, Walidorf U, Kloter U, Gehring WJ: Homology of the eyeless gene of Drosophila to the Small eye gene in mice and Aniridia in humans. Science 1994, 265:785-789.
    • (1994) Science , vol.265 , pp. 785-789
    • Quiring, R.1    Walidorf, U.2    Kloter, U.3    Gehring, W.J.4
  • 27
    • 0028944665 scopus 로고
    • Induction of ectopic eyes by targeted expression of the eyeless genes in Drosophila
    • Halder G, Callaerts P, Gehring WJ: Induction of ectopic eyes by targeted expression of the eyeless genes in Drosophila. Science 1995, 267:1788-1792.
    • (1995) Science , vol.267 , pp. 1788-1792
    • Halder, G.1    Callaerts, P.2    Gehring, W.J.3
  • 28
    • 23444441161 scopus 로고
    • Pax6 is first expressed in a region of ectoderm anterior to the early neural plate: Implications for stepwise determination of the lens
    • Li HS, Yang JM, Jacobean RD, Pasko D, Sundin O: Pax6 is first expressed in a region of ectoderm anterior to the early neural plate: Implications for stepwise determination of the lens. Dev Biol 1994, 162:181-194.
    • (1994) Dev Biol , vol.162 , pp. 181-194
    • Li, H.S.1    Yang, J.M.2    Jacobean, R.D.3    Pasko, D.4    Sundin, O.5
  • 30
    • 0032895297 scopus 로고    scopus 로고
    • Distinct cis-essential modules direct the time-space patterns of the Pax6 gene activity
    • Kammandel B, Chowdhury K, Stoykova A, Aparicio S, Brenner S, Gruss P: Distinct cis-essential modules direct the time-space patterns of the Pax6 gene activity. Dev Biol 1999, 205:79-97.
    • (1999) Dev Biol , vol.205 , pp. 79-97
    • Kammandel, B.1    Chowdhury, K.2    Stoykova, A.3    Aparicio, S.4    Brenner, S.5    Gruss, P.6
  • 32
    • 0029002548 scopus 로고
    • The role of pax6 in eye and nasal development
    • Grindley JC, Davidson DR, Hill RE: The role of pax6 in eye and nasal development. Development 1995, 121:1433-1442.
    • (1995) Development , vol.121 , pp. 1433-1442
    • Grindley, J.C.1    Davidson, D.R.2    Hill, R.E.3
  • 33
    • 0028175561 scopus 로고
    • Uchida rat (rSey): A new mutant rat with craniofacial abnormalities resembling those of the mouse Sey mutant
    • Fujiwara M, Uchida T, Osumi-Yamashita N, Eto K: Uchida rat (rSey): A new mutant rat with craniofacial abnormalities resembling those of the mouse Sey mutant. Differentiation 1994, 57:31 -38.
    • (1994) Differentiation , vol.57 , pp. 31-38
    • Fujiwara, M.1    Uchida, T.2    Osumi-Yamashita, N.3    Eto, K.4
  • 34
    • 0031840442 scopus 로고    scopus 로고
    • Dual roles for Pax-6: A transcriptional represser of lens fiber cell-specific β-crystallin genes
    • Duncan MK, Haynes JI II, Cvecl A, Piatigorsky J: Dual roles for Pax-6: A transcriptional represser of lens fiber cell-specific β-crystallin genes. Mol Cell Biol 1998, 18:5579-5586. This paper describes the evidence that Pax-6 functions as a repressor of β-crystallin promoter, which is consistent with the fact that Pax6 level is high in the lens epithelium where β-crystallins are not expressed, thus proposing the model that relief from Pax-6 repression is involved in activation of β-crystallin genes in the lens fibers.
    • (1998) Mol Cell Biol , vol.18 , pp. 5579-5586
    • Duncan, M.K.1    Haynes J.I. II2    Cvecl, A.3    Piatigorsky, J.4
  • 35
    • 0029013329 scopus 로고
    • Pax-6 is essential for lens-specific expression of zeta-crystallin
    • Richardson J, Cvekl A, Wistow G: Pax-6 is essential for lens-specific expression of zeta-crystallin. Proc Natl Acad Sci USA 1995, 92:4676-4680.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 4676-4680
    • Richardson, J.1    Cvekl, A.2    Wistow, G.3
  • 37
    • 0028869811 scopus 로고
    • Transcriptional regulation of the mouse βa-crystallin gene: Activation dependent on a cyclic AMP-responsive element (DE1/CRE) and a Pax-6-binding site
    • Cvekl A, Kashanchi F, Sax CM, Brady JN, Piatigorsky J: Transcriptional regulation of the mouse βa-crystallin gene: Activation dependent on a cyclic AMP-responsive element (DE1/CRE) and a Pax-6-binding site. Mol Cell Biol 1995, 15:653-660.
    • (1995) Mol Cell Biol , vol.15 , pp. 653-660
    • Cvekl, A.1    Kashanchi, F.2    Sax, C.M.3    Brady, J.N.4    Piatigorsky, J.5
  • 38
    • 0031900978 scopus 로고    scopus 로고
    • Lens-specific gene recruitment of zeta-crystallin through Pax6, Nrl-Maf, and brain suppressor sites
    • Sharon-Friling R, Richardson J, Sperbeck S, Lee D, Rauchman M, Maas R, Swaroop A, Wistow G: Lens-specific gene recruitment of zeta-crystallin through Pax6, Nrl-Maf, and Brain Suppressor Sites. Mol Cell Biol 1998, 18:2067-2076. ζ-Crystallin is expressed in the lens epithelium of the guinea pig via the lens-specific promoter. The authors show that this promoter depends on Pax6- and Maf-binding sites. A short promoter region containing these sites, however, displayed the activity not only in the lens but also in the brain of transgenic mice, and an additional upstream region was required for suppression of the activity in the brain. This paper illustrates a good example of how interplay of transcription factors leads to a lens-specific expression pattern.
    • (1998) Mol Cell Biol , vol.18 , pp. 2067-2076
    • Sharon-Friling, R.1    Richardson, J.2    Sperbeck, S.3    Lee, D.4    Rauchman, M.5    Maas, R.6    Swaroop, A.7    Wistow, G.8
  • 40
    • 0027328532 scopus 로고
    • Overlapping positive and negative regulatory elements determine lens-specific activity of the δ1-crystallin enhancer
    • Kamachi Y, Kondoh H: Overlapping positive and negative regulatory elements determine lens-specific activity of the δ1- Crystallin enhancer. Mol Cell Biol 1993, 13:5206-5215.
    • (1993) Mol Cell Biol , vol.13 , pp. 5206-5215
    • Kamachi, Y.1    Kondoh, H.2
  • 43
    • 0031903569 scopus 로고    scopus 로고
    • Involvement of Sox1, 2 and 3 in the early and subsequent molecular events of lens induction
    • Kamachi Y, Uchikawa M, Collignon J, Lovell-Badge R, Kondoh H: Involvement of Sox1, 2 and 3 in the early and subsequent molecular events of lens induction. Development 1998, 125:2521-2532. We first show that Sox1-3 are essential transcription factors for activation of δ-crystallin enhancer and demonstrate, using chicken embryo, that expression of Sox2/3 in the presumptive lens area of head ectoderm is activated by the inductive influence of the optic vesicle, and Sox1 is activated just before lens fiber differentiation begins. In the mouse, Sox3 is not appreciably expressed in the lens and Sox2 expression is turned off in the lens fiber when Sox1 is activated. The results indicate that Sox2/3 activation is fundamental to the process of lens induction.
    • (1998) Development , vol.125 , pp. 2521-2532
    • Kamachi, Y.1    Uchikawa, M.2    Collignon, J.3    Lovell-Badge, R.4    Kondoh, H.5
  • 44
    • 0032927874 scopus 로고    scopus 로고
    • Mechanism of regulatory target selection by the SOX high-mobility-group domain proteins as revealed by comparison of SOX1/2/3 and SOX9
    • Kamachi Y, Cheah KSE, Kondoh H: Mechanism of regulatory target selection by the SOX high-mobility-group domain proteins as revealed by comparison of SOX1/2/3 and SOX9. Mol Cell Biol 1999, 19:107-120. Crystallin gene activation is achieved by Sox1-3 but not by other Sox proteins. We show that action of Sox proteins requires interaction with specific partner factors bound at a nearby site of the enhancer. This is the mechanism of the specific action of the Sox proteins on individual regulatory sites.
    • (1999) Mol Cell Biol , vol.19 , pp. 107-120
    • Kamachi, Y.1    Cheah, K.S.E.2    Kondoh, H.3
  • 46
    • 0032521460 scopus 로고    scopus 로고
    • SOX1 directly regulates the γ-crystallin genes and is essential for lens development in mice
    • Nishiguchi S, Wood H, Kondoh H, Lovell-Badge R, Episkopou V: SOX1 directly regulates the γ-crystallin genes and is essential for lens development in mice. Genes Dev 1998, 12:776-781. This paper reports a clear-cut knockout mouse analysis of the Sox1 function. The major phenotype is the defect in development of the lens fiber where Sox1 functions as major Sox. All γ-crystallin gene expression is eventually lost and fiber cell elongation is arrested, indicating that these genes and the process are under strict regulation by Sox1 in the mouse.
    • (1998) Genes Dev , vol.12 , pp. 776-781
    • Nishiguchi, S.1    Wood, H.2    Kondoh, H.3    Lovell-Badge, R.4    Episkopou, V.5
  • 47
    • 0031670551 scopus 로고    scopus 로고
    • Gene activation during early stages of lens induction
    • Zygar CA, Cook TL, Grainger RM: Gene activation during early stages of lens induction. Development 1998, 125:3509-3515. A report of elaborate work on Xenopus embryos trying to define the steps leading to lens induction in relation to activation of the regulatory genes, Otx1, Pat6 and Sox3.
    • (1998) Development , vol.125 , pp. 3509-3515
    • Zygar, C.A.1    Cook, T.L.2    Grainger, R.M.3
  • 48
    • 0030707867 scopus 로고    scopus 로고
    • Characterization and early embryonic expression of a neural specific transcription factor xSOX3 in Xenopus laevis
    • Penzel R, Oschwald R, Chen Y, Tacke L, Grunz H: Characterization and early embryonic expression of a neural specific transcription factor xSOX3 in Xenopus laevis. Int J Dev Biol 1997, 41:667-677.
    • (1997) Int J Dev Biol , vol.41 , pp. 667-677
    • Penzel, R.1    Oschwald, R.2    Chen, Y.3    Tacke, L.4    Grunz, H.5
  • 50
    • 0032430772 scopus 로고    scopus 로고
    • BMP4 is essential for lens induction in the mouse embryo
    • Furuta Y, Hogan B: BMP4 is essential for lens induction in the mouse embryo. Genes Dev 1998, 12:3764-3775. BMP4 mutant mice die around the time of lens induction but the authors have here taken advantage of organ culture and show that Sox2 is not induced in the head ectoderm and lens induction does not take place in the mutant eye. Addition of BMP4 to the retina-ectoderm conjugant culture rescues Sox2 expression and lens development in the mutant tissue, whereas addition of BMP4 to the ectoderm alone does not elicit lens development. The results demonstrate that BMP4 is essential for Sox2 induction and initiation of lens differentiation but that BMP4 per se is not an inducer of Sox2.
    • (1998) Genes Dev , vol.12 , pp. 3764-3775
    • Furuta, Y.1    Hogan, B.2
  • 51
    • 0028072795 scopus 로고
    • MafB, a new Maf family transcription activator that can associate with Maf and Fos but not with Jun.
    • Kataoka K, Fujiwara KT, Noda M, Nishizawa M: MafB, a new Maf family transcription activator that can associate with Maf and Fos but not with Jun. Mol Cell Biol 1994, 14:7581 -7591.
    • (1994) Mol Cell Biol , vol.14 , pp. 7581-7591
    • Kataoka, K.1    Fujiwara, K.T.2    Noda, M.3    Nishizawa, M.4
  • 52
    • 0028600585 scopus 로고
    • The mouse segmentation gene kr encodes a novel basic domain-leucine zipper transcription factor
    • Cordes SP, Barsh GS: The mouse segmentation gene kr encodes a novel basic domain-leucine zipper transcription factor. Cell 1994, 79:1025-1034.
    • (1994) Cell , vol.79 , pp. 1025-1034
    • Cordes, S.P.1    Barsh, G.S.2
  • 55
    • 0030049839 scopus 로고    scopus 로고
    • Expression of the bZIP transcription factor gene Nrl in the developing nervous system
    • Liu Q, Ji X, Breitman ML, Hitchcock PF, Swaroop A: Expression of the bZIP transcription factor gene Nrl in the developing nervous system. Oncogene 1996, 12:207-221.
    • (1996) Oncogene , vol.12 , pp. 207-221
    • Liu, Q.1    Ji, X.2    Breitman, M.L.3    Hitchcock, P.F.4    Swaroop, A.5
  • 56
    • 0032478785 scopus 로고    scopus 로고
    • Induction of lens differentiation by activation of a bZIP transcription factor, L-Maf
    • Ogino H, Yasuda K: Induction of lens differentiation by activation of a bZIP transcription factor, L-Maf. Science 1998, 280:115-118. The authors have identified that large Maf proteins, exemplified by L-Maf which is exclusively expressed in the lens, are essential for activation of αA-crystallin promoter. When overexpressed in the neural retina culture and in embryonic ectoderm, L-Maf produces lentoids expressing crystallins.
    • (1998) Science , vol.280 , pp. 115-118
    • Ogino, H.1    Yasuda, K.2
  • 58
    • 0029784507 scopus 로고    scopus 로고
    • Chicken homeobox gene Prox1 related to Drosophila prospero is expressed in the developing lens and retina
    • Tomarev SI, Sundin O, Banerjee-Basu S, Duncan M, Yang JM, Piatigorsky J: Chicken homeobox gene Prox1 related to Drosophila prospero is expressed in the developing lens and retina. Dev Dyn 1996, 206:354-367.
    • (1996) Dev Dyn , vol.206 , pp. 354-367
    • Tomarev, S.I.1    Sundin, O.2    Banerjee-Basu, S.3    Duncan, M.4    Yang, J.M.5    Piatigorsky, J.6
  • 59
    • 0033018615 scopus 로고    scopus 로고
    • Prox1 function is crucial for mouse lens fibre elongation
    • Wigle JT, Chowdhury K, Gruss P, Oliver G: Prox1 function is crucial for mouse lens fibre elongation. Nat Genet 1999, 21:318-322. The authors here show that lens development in Prox1 mutant mice does not proceed beyond the lens vesicle stage. Through analysis of a set of appropriate molecular markers, they demonstrate that lens-fiber differentiation is initiated, as indicated by synthesis of most fiber-specific crystallins and intermediate filament components, but is arrested at its initial stage failing to turn off of E-cadherin or to activate cyclin-dependent kinase inhibitors. Prox1 is thus essential for transition from lens epithelium to lens fiber.
    • (1999) Nat Genet , vol.21 , pp. 318-322
    • Wigle, J.T.1    Chowdhury, K.2    Gruss, P.3    Oliver, G.4
  • 60
    • 0029617682 scopus 로고
    • Six3, a murine homologue of the sine oculis gene, demarcates the most anterior border of the developing neural plate and is expressed during eye development
    • Oliver G, Mailhos A, Wehr R, Copeland NG, Jenkins NA, Gruss P: Six3, a murine homologue of the sine oculis gene, demarcates the most anterior border of the developing neural plate and is expressed during eye development. Development 1995, 121:4045-4055.
    • (1995) Development , vol.121 , pp. 4045-4055
    • Oliver, G.1    Mailhos, A.2    Wehr, R.3    Copeland, N.G.4    Jenkins, N.A.5    Gruss, P.6
  • 61
    • 0031929296 scopus 로고    scopus 로고
    • Expression pattern of cSix3, a member of the Six/sine oculis family of transcription factors
    • Bovolenta P, Mallamaci A, Ruelles L, Boncinelli E: Expression pattern of cSix3, a member of the Six/sine oculis family of transcription factors. Mech Dev 1998, 70:201 -203.
    • (1998) Mech Dev , vol.70 , pp. 201-203
    • Bovolenta, P.1    Mallamaci, A.2    Ruelles, L.3    Boncinelli, E.4
  • 62
    • 0030460218 scopus 로고    scopus 로고
    • Ectopic lens induction in fish in response to the murine homeobox gene Six3
    • Oliver G, Loosli F, Koster R, Wittbrodt J, Gruss P: Ectopic lens induction in fish in response to the murine homeobox gene Six3. Mech Dev 1996, 60:233-239.
    • (1996) Mech Dev , vol.60 , pp. 233-239
    • Oliver, G.1    Loosli, F.2    Koster, R.3    Wittbrodt, J.4    Gruss, P.5
  • 63
    • 0027409151 scopus 로고
    • An everted repeat mediates retinoic acid induction of the γF-crystallin gene: Evidence for a direct role for retinoids in lens development
    • Tini M, Otulakowski G, Breitman M, Tsui L, Giguere V: An everted repeat mediates retinoic acid induction of the γF-crystallin gene: Evidence for a direct role for retinoids in lens development. Genes Dev 1993, 7:295-307.
    • (1993) Genes Dev , vol.7 , pp. 295-307
    • Tini, M.1    Otulakowski, G.2    Breitman, M.3    Tsui, L.4    Giguere, V.5
  • 64
    • 0028088752 scopus 로고
    • Function of the retinoic acid receptors (RARs during development. (I craniofacial and skeletal abnormalities in RAR double mutants
    • Lohnes D, Mark M, Mendelsohn C, Dolle P, Dierich A, Gorry P, Gansmuller A, Chambon P: Function of the retinoic acid receptors (RARs) during development. (I) craniofacial and skeletal abnormalities in RAR double mutants. Development 1994, 120:2723-2748.
    • (1994) Development , vol.120 , pp. 2723-2748
    • Lohnes, D.1    Mark, M.2    Mendelsohn, C.3    Dolle, P.4    Dierich, A.5    Gorry, P.6    Gansmuller, A.7    Chambon, P.8
  • 65
    • 0032189841 scopus 로고    scopus 로고
    • A novel alternative spliced variant of the transcription factor AP2α is expressed in the murine ocular lens
    • Otaka-Maruyama C, Hanaoka F, Chepelinsky AB: A novel alternative spliced variant of the transcription factor AP2α is expressed in the murine ocular lens. Dev Biol 1998, 202:125-135.
    • (1998) Dev Biol , vol.202 , pp. 125-135
    • Otaka-Maruyama, C.1    Hanaoka, F.2    Chepelinsky, A.B.3
  • 66
    • 0029932086 scopus 로고    scopus 로고
    • Transcription factor AP-2 essential for cranial closure and craniofacial development
    • Schore H, Meier P, Buchert M, Jaenisch R, Mitchell PJ: Transcription factor AP-2 essential for cranial closure and craniofacial development Nature 1996, 381:235-238.
    • (1996) Nature , vol.381 , pp. 235-238
    • Schore, H.1    Meier, P.2    Buchert, M.3    Jaenisch, R.4    Mitchell, P.J.5
  • 68
    • 0033616621 scopus 로고    scopus 로고
    • Requirement for the c-Maf transcription factor in crystallin gene regulation and lens development
    • Kim JI, Li T, Ho I-C, Grusby MJ, Glimcher LH: Requirement for the c-Maf transcription factor in crystallin gene regulation and lens development Proc Natl Acad Sci USA 1999, 96:3781 -3785.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 3781-3785
    • Kim, J.I.1    Li, T.2    Ho, I.-C.3    Grusby, M.J.4    Glimcher, L.H.5
  • 70
    • 0026071413 scopus 로고
    • Interaction of a lens cell transcription factor with the proximal domain of the mouse γF-crystallin promoter
    • Liu Q, Tini M, Tsui L-C, Breitman ML: Interaction of a lens cell transcription factor with the proximal domain of the mouse γF-crystallin promoter. Mol Celt Biol 1991, 11:1531 -1537.
    • (1991) Mol Celt Biol , vol.11 , pp. 1531-1537
    • Liu, Q.1    Tini, M.2    Tsui, L.-C.3    Breitman, M.L.4
  • 71
    • 0027269795 scopus 로고
    • Developmental regulation and cell type-specific expression of the murine γF-crystallin gene is mediated through a lens-specific element containing the γF-1 binding site
    • Goring DR, Bryce DM, Tsui L-C, Breitman ML, Liu Q: Developmental regulation and cell type-specific expression of the murine γF-crystallin gene is mediated through a lens-specific element containing the γF-1 binding site. Dev Dyn 1993, 196:143-152.
    • (1993) Dev Dyn , vol.196 , pp. 143-152
    • Goring, D.R.1    Bryce, D.M.2    Tsui, L.-C.3    Breitman, M.L.4    Liu, Q.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.