Enhanced efficacy of 7-hydroxy-3-methoxycadalene via glycosylation in in vivo xenograft study

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 22, 2007, Pages 6335-6339

  Lee, Hyang Yeon ^a   Kwon, Jung Taek ^a   Koh, Minseob ^a   Cho, Myung Haing ^a   Park, Seung Bum ^a  

^a Seoul National University   (South Korea)

Author keywords

Anticancer; Cadalene; Drug delivery; Glycosylation; Prodrug

Indexed keywords

7 HYDROXY 3 METHOXYCADALENE; ANTINEOPLASTIC AGENT; BETA GLYCOSYLATED O CADALENE; FLAVONOID; PRODRUG; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG EFFICACY; DRUG ISOLATION; DRUG SOLUBILITY; DRUG SYNTHESIS; GLYCOSYLATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MEDICINAL PLANT; MOUSE; NONHUMAN; PHYSICAL CHEMISTRY; STEREOCHEMISTRY; TUMOR VOLUME; TUMOR XENOGRAFT; ZELKOVA SERRATA;

ADMINISTRATION, ORAL; ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL SURVIVAL; DRUG DELIVERY SYSTEMS; GLYCOSYLATION; HUMANS; MICE; MOLECULAR STRUCTURE; NAPHTHALENES; NEOPLASMS; PHYTOTHERAPY; PLANT EXTRACTS; SOLUBILITY; TUMOR BURDEN; ULMACEAE; XENOGRAFT MODEL ANTITUMOR ASSAYS;

MUS; ZELKOVA SERRATA;

EID: 35148828107     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.08.071     Document Type: Article

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