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Volumn 46, Issue 1-2, 1997, Pages 129-137

Targeted delivery of drugs and proteins to the liver via receptor-mediated endocytosis

Author keywords

Galactosylated macromolecules; Hepatic targeting; Liver; Pharmacokinetics; Sugar recognition; Vitamin K5

Indexed keywords

AMYLOSE; ASIALOGLYCOPROTEIN RECEPTOR; CARBOXYMETHYLDEXTRAN; CARBOXYMETHYLSTARCH SODIUM; DRUG CARRIER; GALACTOSE; POLYGLUTAMIC ACID; VITAMIN K GROUP; WARFARIN;

EID: 0031039539     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(96)01577-5     Document Type: Conference Paper
Times cited : (59)

References (35)
  • 1
    • 0020021127 scopus 로고
    • Carbohydrate-specific receptors of the liver
    • G. Ashwell and J. Harford, Carbohydrate-specific receptors of the liver, Annu. Rev. Biochem. 51 (1982) 531-554.
    • (1982) Annu. Rev. Biochem. , vol.51 , pp. 531-554
    • Ashwell, G.1    Harford, J.2
  • 2
    • 0024510074 scopus 로고
    • Covalent and noncovalent protein binding of drugs: Implications for hepatic clearance, storage, and cell-specific drug delivery
    • D.K.F. Meijer and P. van der Sluijs, Covalent and noncovalent protein binding of drugs: Implications for hepatic clearance, storage, and cell-specific drug delivery, Pharm. Res. 6 (1989) 105-118.
    • (1989) Pharm. Res. , vol.6 , pp. 105-118
    • Meijer, D.K.F.1    Van Der Sluijs, P.2
  • 3
    • 0028079888 scopus 로고
    • An evaluation of receptor-mediated gene transfer using synthetic DNA-ligand complexes
    • J.C. Perales, T. Ferkol, M. Molas and R.W. Hanson, An evaluation of receptor-mediated gene transfer using synthetic DNA-ligand complexes, Eur. J. Biochem. 226 (1994) 255-266.
    • (1994) Eur. J. Biochem. , vol.226 , pp. 255-266
    • Perales, J.C.1    Ferkol, T.2    Molas, M.3    Hanson, R.W.4
  • 4
    • 0029136052 scopus 로고
    • DNA complexes with polycations for the delivery of genetic material into cells
    • A.V. Kabanov and V.A. Kabanov, DNA complexes with polycations for the delivery of genetic material into cells, Bioconjugate Chem. 6 (1995) 7-20.
    • (1995) Bioconjugate Chem. , vol.6 , pp. 7-20
    • Kabanov, A.V.1    Kabanov, V.A.2
  • 5
  • 6
    • 0021235507 scopus 로고
    • Disposition and pharmacokinetics of a polymeric prodrug of mitomycin C, mitomycin C-dextran conjugate, in the rat
    • M. Hashida, A. Kato, Y. Takakura and H. Sezaki, Disposition and pharmacokinetics of a polymeric prodrug of mitomycin C, mitomycin C-dextran conjugate, in the rat, Drug Metab. Dispos. 12 (1984) 482-499.
    • (1984) Drug Metab. Dispos. , vol.12 , pp. 482-499
    • Hashida, M.1    Kato, A.2    Takakura, Y.3    Sezaki, H.4
  • 7
    • 0002079949 scopus 로고
    • Disposition and tumor localization of mitomycin C-dextran conjugates in mice
    • Y. Takakura, A. Takagi, M. Hashida and H. Sezaki, Disposition and tumor localization of mitomycin C-dextran conjugates in mice, Pharm. Res. 4 (1987) 293-300.
    • (1987) Pharm. Res. , vol.4 , pp. 293-300
    • Takakura, Y.1    Takagi, A.2    Hashida, M.3    Sezaki, H.4
  • 8
    • 0023268773 scopus 로고
    • Development of a novel polymeric prodrug of mitomycin C, mitomycin C-dextran conjugate with anionic charge. II. Disposition and pharmacokinetics following intravenous and intramuscular administration
    • Y. Takakura, R. Atsumi, M. Hashida and H. Sezaki, Development of a novel polymeric prodrug of mitomycin C, mitomycin C-dextran conjugate with anionic charge. II. Disposition and pharmacokinetics following intravenous and intramuscular administration, Int. J. Pharm. 37 (1987) 145-154.
    • (1987) Int. J. Pharm. , vol.37 , pp. 145-154
    • Takakura, Y.1    Atsumi, R.2    Hashida, M.3    Sezaki, H.4
  • 9
    • 0024410772 scopus 로고
    • Soluble macromolecular carriers for the delivery of anticancer drugs
    • H. Sezaki, Y. Takakura and M. Hashida, Soluble macromolecular carriers for the delivery of anticancer drugs, Adv. Drug Deliv. Rev. 3 (1989) 247-266.
    • (1989) Adv. Drug Deliv. Rev. , vol.3 , pp. 247-266
    • Sezaki, H.1    Takakura, Y.2    Hashida, M.3
  • 10
    • 0027982550 scopus 로고
    • Pharmacokinetics in design of polymeric drug delivery systems
    • M. Hashida and Y. Takakura, Pharmacokinetics in design of polymeric drug delivery systems, J. Control. Release 31 (1994) 163-171.
    • (1994) J. Control. Release , vol.31 , pp. 163-171
    • Hashida, M.1    Takakura, Y.2
  • 11
    • 0028833556 scopus 로고
    • Macromolecular drug carrier systems in cancer chemotherapy: Macromolecular prodrugs
    • Y. Takakura and M. Hashida, Macromolecular drug carrier systems in cancer chemotherapy: macromolecular prodrugs, Crit. Rev. Oncol. Hematol. 18 (1995) 207-231.
    • (1995) Crit. Rev. Oncol. Hematol. , vol.18 , pp. 207-231
    • Takakura, Y.1    Hashida, M.2
  • 12
    • 0028967474 scopus 로고
    • Design for cell-specific targeting of proteins utilizing sugar-recognition mechanism: Effect of molecular weight of proteins on targeting efficiency
    • M. Nishikawa, H. Hirabayashi, Y. Takakura and M. Hashida, Design for cell-specific targeting of proteins utilizing sugar-recognition mechanism: Effect of molecular weight of proteins on targeting efficiency, Pharm. Res. 12 (1995) 209-214.
    • (1995) Pharm. Res. , vol.12 , pp. 209-214
    • Nishikawa, M.1    Hirabayashi, H.2    Takakura, Y.3    Hashida, M.4
  • 13
    • 0027185699 scopus 로고
    • Synthesis and pharmacokinetics of a new liver-specific carrier, glycosylated carboxymethyl-dextran, and its application to drug targeting
    • M. Nishikawa, A. Kamijo, T. Fujita, Y. Takakura, H. Sezaki and M. Hashida, Synthesis and pharmacokinetics of a new liver-specific carrier, glycosylated carboxymethyl-dextran, and its application to drug targeting, Pharm. Res. 10 (1993) 1253-1261.
    • (1993) Pharm. Res. , vol.10 , pp. 1253-1261
    • Nishikawa, M.1    Kamijo, A.2    Fujita, T.3    Takakura, Y.4    Sezaki, H.5    Hashida, M.6
  • 14
    • 0029014068 scopus 로고
    • Galactosylated proteins are recognized by the liver according to the surface density of galactose moieties
    • M. Nishikawa, C. Miyazaki, F. Yamashita, Y. Takakura and M. Hashida, Galactosylated proteins are recognized by the liver according to the surface density of galactose moieties, Am. J. Physiol. 268 (1995) G849-G856.
    • (1995) Am. J. Physiol. , vol.268
    • Nishikawa, M.1    Miyazaki, C.2    Yamashita, F.3    Takakura, Y.4    Hashida, M.5
  • 15
    • 0023103931 scopus 로고
    • Warfarin poisoning and vitamin K antagonism in rat and human liver. Design of a system in vitro that mimics the situation in vivo
    • R. Wallin and L.F. Martin, Warfarin poisoning and vitamin K antagonism in rat and human liver. Design of a system in vitro that mimics the situation in vivo, Biochem. J. 241 (1987) 389-396.
    • (1987) Biochem. J. , vol.241 , pp. 389-396
    • Wallin, R.1    Martin, L.F.2
  • 16
    • 0025148495 scopus 로고
    • Disposition characteristics of macromolecules in tumor-bearing mice
    • Y. Takakura, T. Fujita, M. Hashida and H. Sezaki, Disposition characteristics of macromolecules in tumor-bearing mice, Pharm. Res. 7 (1990) 339-346.
    • (1990) Pharm. Res. , vol.7 , pp. 339-346
    • Takakura, Y.1    Fujita, T.2    Hashida, M.3    Sezaki, H.4
  • 17
    • 0017201417 scopus 로고
    • 2-imino-2-methoxyethyl 1-thioglycosides: New reagents for attaching sugars to proteins
    • Y.C. Lee, C.P. Stowell and M.K. Krantz, 2-imino-2-methoxyethyl 1-thioglycosides: New reagents for attaching sugars to proteins, Biochemistry 15 (1976) 3956-3963.
    • (1976) Biochemistry , vol.15 , pp. 3956-3963
    • Lee, Y.C.1    Stowell, C.P.2    Krantz, M.K.3
  • 18
    • 0029896222 scopus 로고    scopus 로고
    • Development and pharmacokinetics of galactosylated poly-L-glutamic acid as a biodegradable carrier for liver-specific drug delivery
    • H. Hirabayashi, M. Nishikawa, Y. Takakura and M. Hashida, Development and pharmacokinetics of galactosylated poly-L-glutamic acid as a biodegradable carrier for liver-specific drug delivery, Pharm. Res. 13 (1996) 880-884.
    • (1996) Pharm. Res. , vol.13 , pp. 880-884
    • Hirabayashi, H.1    Nishikawa, M.2    Takakura, Y.3    Hashida, M.4
  • 23
    • 0027368237 scopus 로고
    • Intracellular metabolism of indium-111-DTPA-labeled receptor targeted proteins
    • J.R. Duncan and M.J. Welch, Intracellular metabolism of indium-111-DTPA-labeled receptor targeted proteins, J. Nucl. Med. 34 (1993) 1728-1738.
    • (1993) J. Nucl. Med. , vol.34 , pp. 1728-1738
    • Duncan, J.R.1    Welch, M.J.2
  • 24
    • 0028227355 scopus 로고
    • A biological method to evaluate bifunctional chelating agents to label antibodies with metallic radionuclides
    • Y. Arano, T. Mukai, T. Uezono, K. Wakisaka, H. Motonari, H. Akizawa, Y. Taoka and A. Yokoyama, A biological method to evaluate bifunctional chelating agents to label antibodies with metallic radionuclides, J. Nucl. Med. 35 (1994) 890-898.
    • (1994) J. Nucl. Med. , vol.35 , pp. 890-898
    • Arano, Y.1    Mukai, T.2    Uezono, T.3    Wakisaka, K.4    Motonari, H.5    Akizawa, H.6    Taoka, Y.7    Yokoyama, A.8
  • 25
    • 0025099617 scopus 로고
    • Metabolism of indium chelates attached to monoclonal antibody: Minimal transchelation of indium from benzyl-EDTA chelate in vivo
    • S.V. Deshpande, R. Subramanian, M.J. McCall, S.J. De-Nardo, G.L. DeNardo and C.F. Meares, Metabolism of indium chelates attached to monoclonal antibody: Minimal transchelation of indium from benzyl-EDTA chelate in vivo, J. Nucl. Med. 31 (1990) 218-224.
    • (1990) J. Nucl. Med. , vol.31 , pp. 218-224
    • Deshpande, S.V.1    Subramanian, R.2    McCall, M.J.3    De-Nardo, S.J.4    DeNardo, G.L.5    Meares, C.F.6
  • 26
    • 0019854279 scopus 로고
    • A pharmacokinetic analysis program (MULTI) for microcomputer
    • K. Yamaoka, Y. Tanigawara, T. Nakagawa and T. Uno, A pharmacokinetic analysis program (MULTI) for microcomputer, J. Pharmacobio-Dyn. 4 (1981) 879-885.
    • (1981) J. Pharmacobio-Dyn. , vol.4 , pp. 879-885
    • Yamaoka, K.1    Tanigawara, Y.2    Nakagawa, T.3    Uno, T.4
  • 27
    • 0014027409 scopus 로고
    • The activity of human placenta microsomes and brain particles in blood coagulation
    • W.J. Williams, The activity of human placenta microsomes and brain particles in blood coagulation, J. Biol. Chem. 241 (1966) 1840-1846.
    • (1966) J. Biol. Chem. , vol.241 , pp. 1840-1846
    • Williams, W.J.1
  • 28
    • 0017976656 scopus 로고
    • Glomerular permselectivity: Barrier function based on discrimination of molecular size and charge
    • B.M. Brenner, T.H. Hostetter and H.D. Humes, Glomerular permselectivity: Barrier function based on discrimination of molecular size and charge, Am. J. Physiol. 234 (1978) F455-F460.
    • (1978) Am. J. Physiol. , vol.234
    • Brenner, B.M.1    Hostetter, T.H.2    Humes, H.D.3
  • 29
  • 30
    • 0028265246 scopus 로고
    • Manipulation of renal disposition of human recombinant superoxide dismutase by chemical modification
    • K. Mihara, K. Sawai, Y. Takakura and M. Hashida, Manipulation of renal disposition of human recombinant superoxide dismutase by chemical modification, Biol. Pharm. Bull. 17 (1994) 296-301.
    • (1994) Biol. Pharm. Bull. , vol.17 , pp. 296-301
    • Mihara, K.1    Sawai, K.2    Takakura, Y.3    Hashida, M.4
  • 31
    • 0021245955 scopus 로고
    • Tc-99m-galactosyl-neoglycoalbumin: In vitro characterization of receptor-mediated binding
    • D.R. Vera, K.A. Krohn, R.C. Stadalnik and P.O. Scheibe, Tc-99m-galactosyl-neoglycoalbumin: In vitro characterization of receptor-mediated binding, J. Nucl. Med. 25 (1984) 779-787.
    • (1984) J. Nucl. Med. , vol.25 , pp. 779-787
    • Vera, D.R.1    Krohn, K.A.2    Stadalnik, R.C.3    Scheibe, P.O.4
  • 32
    • 0021099058 scopus 로고
    • Binding of synthetic oligosaccharides to the hepatic Gal/GalNAc lectin. Dependence on fine structural features
    • Y.C. Lee, R.R. Townsend, M.R. Hardy, J. Lünngren, J. Arnarp, M. Haraldsson and H. Lünn, Binding of synthetic oligosaccharides to the hepatic Gal/GalNAc lectin. Dependence on fine structural features, J. Biol. Chem. 258 (1983) 199-202.
    • (1983) J. Biol. Chem. , vol.258 , pp. 199-202
    • Lee, Y.C.1    Townsend, R.R.2    Hardy, M.R.3    Lünngren, J.4    Arnarp, J.5    Haraldsson, M.6    Lünn, H.7
  • 33
    • 0023055761 scopus 로고
    • Binding of N-linked bovine fetuin glycopeptides to isolated rabbit hepatocytes: Gal/GalNAc hepatic lectin discrimination between Galβ(1,4)GalNAc and Galβ(1,3)GalNAc in a triantennary structure
    • R.R. Townsend, M.R. Hardy, T.C. Wong and Y.C. Lee, Binding of N-linked bovine fetuin glycopeptides to isolated rabbit hepatocytes: Gal/GalNAc hepatic lectin discrimination between Galβ(1,4)GalNAc and Galβ(1,3)GalNAc in a triantennary structure, Biochemistry 25 (1986) 5716-5725.
    • (1986) Biochemistry , vol.25 , pp. 5716-5725
    • Townsend, R.R.1    Hardy, M.R.2    Wong, T.C.3    Lee, Y.C.4
  • 34
  • 35
    • 0028351444 scopus 로고
    • Pharmacokinetics of succinylated proteins and dextran sulfate in mice: Implications for hepatic targeting of protein drugs by direct succinylation via scavenger receptors
    • Y. Takakura, T. Fujita, H. Furitsu, M. Nishikawa, H. Sezaki and M. Hashida, Pharmacokinetics of succinylated proteins and dextran sulfate in mice: Implications for hepatic targeting of protein drugs by direct succinylation via scavenger receptors, Int. J. Pharm. 105 (1994) 19-29.
    • (1994) Int. J. Pharm. , vol.105 , pp. 19-29
    • Takakura, Y.1    Fujita, T.2    Furitsu, H.3    Nishikawa, M.4    Sezaki, H.5    Hashida, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.