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Volumn 58, Issue 4, 2007, Pages 705-716

Comparison of single- and dual-tracer pharmacokinetic modeling of dynamic contrast-enhanced MRI data using low, medium, and high molecular weight contrast agents

Author keywords

Dual tracer; Dynamic contrast enhanced MRI; MR contrast agents; Pharmacokinetic models; Single tracer

Indexed keywords

BLOOD VESSELS; IMAGE SEGMENTATION; MAGNETIC RESONANCE IMAGING; MAMMALS; MOLECULAR IMAGING; MOLECULAR WEIGHT; PHARMACOKINETICS; PROTEINS; TUMORS;

EID: 35048826158     PISSN: 07403194     EISSN: 15222594     Source Type: Journal    
DOI: 10.1002/mrm.21411     Document Type: Article
Times cited : (17)

References (43)
  • 1
    • 0026083903 scopus 로고
    • Tumor angiogenesis and metastasis - correlation in invasive breast carcinoma
    • Weidner N, Semple JP, Welch WR, Folkman J. Tumor angiogenesis and metastasis - correlation in invasive breast carcinoma. N Engl J Med 1991;324:1-8.
    • (1991) N Engl J Med , vol.324 , pp. 1-8
    • Weidner, N.1    Semple, J.P.2    Welch, W.R.3    Folkman, J.4
  • 2
    • 0022495733 scopus 로고
    • Microvascular permeability of normal and neoplastic tissues
    • Gerlowski LE, Jain RK. Microvascular permeability of normal and neoplastic tissues. Microvasc Res 1986;31:288-305.
    • (1986) Microvasc Res , vol.31 , pp. 288-305
    • Gerlowski, L.E.1    Jain, R.K.2
  • 3
    • 0029328266 scopus 로고
    • Intratumor microvessel density as a prognostic factor in cancer
    • Weidner N. Intratumor microvessel density as a prognostic factor in cancer. Am J Pathol 1995;147:9-19.
    • (1995) Am J Pathol , vol.147 , pp. 9-19
    • Weidner, N.1
  • 4
    • 0035144670 scopus 로고    scopus 로고
    • Clinical significance of determination of surrogate markers of angiogenesis in breast cancer
    • Gasparini G. Clinical significance of determination of surrogate markers of angiogenesis in breast cancer. Crit Rev Oncol Hematol 2001;37:97-114.
    • (2001) Crit Rev Oncol Hematol , vol.37 , pp. 97-114
    • Gasparini, G.1
  • 5
    • 0023788067 scopus 로고
    • Identification and characterization of the blood vessels of solid tumors that are leaky to circulating macromolecules
    • Dvorak HF, Nagy JA, Dvorak JT, Dvorak AM. Identification and characterization of the blood vessels of solid tumors that are leaky to circulating macromolecules. Am J Pathol 1988;133:95-109.
    • (1988) Am J Pathol , vol.133 , pp. 95-109
    • Dvorak, H.F.1    Nagy, J.A.2    Dvorak, J.T.3    Dvorak, A.M.4
  • 6
    • 0020682224 scopus 로고
    • FITC-Dextrans as tracers for macromolecular movements in the nervous system. A freeze-drying method for dextrans of various molecular sizes injected into normal animals
    • Hultstrom D, Malmgren L, Gilstring D, Olsson Y. FITC-Dextrans as tracers for macromolecular movements in the nervous system. A freeze-drying method for dextrans of various molecular sizes injected into normal animals. Acta Neuropathol 1983;59:53-62.
    • (1983) Acta Neuropathol , vol.59 , pp. 53-62
    • Hultstrom, D.1    Malmgren, L.2    Gilstring, D.3    Olsson, Y.4
  • 7
    • 0018887608 scopus 로고
    • Differences between the peripheral and the central nervous system in permeability to sodium fluorescein
    • Malmgren LT, Olsson Y. Differences between the peripheral and the central nervous system in permeability to sodium fluorescein. J Comp Neurol 1980;191:103-107.
    • (1980) J Comp Neurol , vol.191 , pp. 103-107
    • Malmgren, L.T.1    Olsson, Y.2
  • 8
    • 18844479070 scopus 로고    scopus 로고
    • Uterine cervical carcinoma: Comparison of standard and pharmacokinetic analysis of time-intensity curves for assessment of tumor angiogenesis and patient survival
    • Hawighorst H, Knapstein PG, Knopp MV, Weikel W, Brix G, Zuna I, Schonberg SO, Essig M, Vaupel P, van Kaick G. Uterine cervical carcinoma: comparison of standard and pharmacokinetic analysis of time-intensity curves for assessment of tumor angiogenesis and patient survival. Cancer Res 1998;58:3598-3602.
    • (1998) Cancer Res , vol.58 , pp. 3598-3602
    • Hawighorst, H.1    Knapstein, P.G.2    Knopp, M.V.3    Weikel, W.4    Brix, G.5    Zuna, I.6    Schonberg, S.O.7    Essig, M.8    Vaupel, P.9    van Kaick, G.10
  • 9
    • 0029127219 scopus 로고
    • Current pathologic methods for measuring intratumoral microvessel density within breast carcinoma and other solid tumors
    • Weidner N. Current pathologic methods for measuring intratumoral microvessel density within breast carcinoma and other solid tumors. Breast Cancer Res Treat 1995;36:169-180.
    • (1995) Breast Cancer Res Treat , vol.36 , pp. 169-180
    • Weidner, N.1
  • 10
    • 0035211504 scopus 로고    scopus 로고
    • Angiogenesis-dependent diseases
    • Folkman J. Angiogenesis-dependent diseases. Semin Oncol 2001;28:536-542.
    • (2001) Semin Oncol , vol.28 , pp. 536-542
    • Folkman, J.1
  • 11
    • 7044253187 scopus 로고    scopus 로고
    • MRI monitoring of Avastin antiangiogenesis therapy using B22956/1, a new blood pool contrast agent, in an experimental model of human cancer
    • Preda A, Novikov V, Moglich M, Turetschek K, Shames DM, Brasch RC, Cavagna FM, Roberts TP. MRI monitoring of Avastin antiangiogenesis therapy using B22956/1, a new blood pool contrast agent, in an experimental model of human cancer. J Magn Reson Imaging 2004;20:865-873.
    • (2004) J Magn Reson Imaging , vol.20 , pp. 865-873
    • Preda, A.1    Novikov, V.2    Moglich, M.3    Turetschek, K.4    Shames, D.M.5    Brasch, R.C.6    Cavagna, F.M.7    Roberts, T.P.8
  • 12
    • 0032711751 scopus 로고    scopus 로고
    • Pharmacokinetic analysis of neoplasms using contrast-enhanced dynamic magnetic resonance imaging
    • Parker GJ, Tofts PS. Pharmacokinetic analysis of neoplasms using contrast-enhanced dynamic magnetic resonance imaging. Top Magn Reson Imaging 1999;10:130-142.
    • (1999) Top Magn Reson Imaging , vol.10 , pp. 130-142
    • Parker, G.J.1    Tofts, P.S.2
  • 13
    • 3042719089 scopus 로고    scopus 로고
    • Tumor microvascular changes in antiangiogenic treatment: Assessment by magnetic resonance contrast media of different molecular weights
    • Turetschek K, Preda A, Novikov V, Brasch RC, Weinmann HJ, Wunderbaldinger P, Roberts TP. Tumor microvascular changes in antiangiogenic treatment: assessment by magnetic resonance contrast media of different molecular weights. J Magn Reson Imaging 2004;20:138-144.
    • (2004) J Magn Reson Imaging , vol.20 , pp. 138-144
    • Turetschek, K.1    Preda, A.2    Novikov, V.3    Brasch, R.C.4    Weinmann, H.J.5    Wunderbaldinger, P.6    Roberts, T.P.7
  • 14
    • 0032145497 scopus 로고    scopus 로고
    • Non-invasive in vivo mapping of tumour vascular and interstitial volume fractions
    • Weissleder R, Cheng HC, Marecos E, Kwong K. Bogdanov A Jr. Non-invasive in vivo mapping of tumour vascular and interstitial volume fractions. Eur J Cancer 1998;34:1448-1454.
    • (1998) Eur J Cancer , vol.34 , pp. 1448-1454
    • Weissleder, R.1    Cheng, H.C.2    Marecos, E.3    Kwong, K.4    Bogdanov Jr., A.5
  • 15
    • 0022599154 scopus 로고
    • Extravascular transport in normal and tumor tissues
    • Jain RK, Gerlowski LE. Extravascular transport in normal and tumor tissues. Crit Rev Oncol Hematol 1986;5:115-170.
    • (1986) Crit Rev Oncol Hematol , vol.5 , pp. 115-170
    • Jain, R.K.1    Gerlowski, L.E.2
  • 17
    • 0030750245 scopus 로고    scopus 로고
    • In vivo imaging of extraction fraction of low molecular weight MR contrast agents and perfusion rate in rodent tumors
    • Kovar DA, Lewis MZ, River JN, Lipton MJ, Karczmar GS. In vivo imaging of extraction fraction of low molecular weight MR contrast agents and perfusion rate in rodent tumors. Magn Reson Med 1997;38:259-268.
    • (1997) Magn Reson Med , vol.38 , pp. 259-268
    • Kovar, D.A.1    Lewis, M.Z.2    River, J.N.3    Lipton, M.J.4    Karczmar, G.S.5
  • 18
    • 0031688688 scopus 로고    scopus 로고
    • Correlation of dynamic contrast-enhanced MR imaging with histologic tumor grade: Comparison of macromolecular and small-molecular contrast media
    • Daldrup H, Shames DM, Wendland M, Okuhata Y, Link TM, Rosenau W, Lu Y, Brasch RC. Correlation of dynamic contrast-enhanced MR imaging with histologic tumor grade: comparison of macromolecular and small-molecular contrast media. AJR Am J Roentgenol 1998;171:941-949.
    • (1998) AJR Am J Roentgenol , vol.171 , pp. 941-949
    • Daldrup, H.1    Shames, D.M.2    Wendland, M.3    Okuhata, Y.4    Link, T.M.5    Rosenau, W.6    Lu, Y.7    Brasch, R.C.8
  • 19
    • 0033007860 scopus 로고    scopus 로고
    • Characterization of N-ethyl-N-nitrosourea-induced malignant and benign breast tumors in rats by using three MR contrast agents
    • Su MY, Wang Z, Carpenter PM, Lao X, Muhler A, Nalcioglu O. Characterization of N-ethyl-N-nitrosourea-induced malignant and benign breast tumors in rats by using three MR contrast agents. J Magn Reson Imaging 1999;9:177-186.
    • (1999) J Magn Reson Imaging , vol.9 , pp. 177-186
    • Su, M.Y.1    Wang, Z.2    Carpenter, P.M.3    Lao, X.4    Muhler, A.5    Nalcioglu, O.6
  • 20
    • 0031886171 scopus 로고    scopus 로고
    • Tumor characterization with dynamic contrast-enhanced MRI using MR contrast agents of various molecular weights
    • Su MY, Muhler A, Lao X, Nalcioglu O. Tumor characterization with dynamic contrast-enhanced MRI using MR contrast agents of various molecular weights. Magn Reson Med 1998;39:259-269.
    • (1998) Magn Reson Med , vol.39 , pp. 259-269
    • Su, M.Y.1    Muhler, A.2    Lao, X.3    Nalcioglu, O.4
  • 21
    • 0033647178 scopus 로고    scopus 로고
    • Simultaneous MRI measurement of blood flow, blood volume, and capillary permeability in mammary tumors using two different contrast agents
    • Henderson E, Sykes J, Drost D, Weinmann HJ, Rutt BK, Lee TY. Simultaneous MRI measurement of blood flow, blood volume, and capillary permeability in mammary tumors using two different contrast agents. J Magn Reson Imaging 2000;12:991-1003.
    • (2000) J Magn Reson Imaging , vol.12 , pp. 991-1003
    • Henderson, E.1    Sykes, J.2    Drost, D.3    Weinmann, H.J.4    Rutt, B.K.5    Lee, T.Y.6
  • 22
    • 0022653255 scopus 로고
    • Differential macromolecular leakage from the vasculature of tumors
    • Heuser LS, Miller FN. Differential macromolecular leakage from the vasculature of tumors. Cancer 1986;57:461-464.
    • (1986) Cancer , vol.57 , pp. 461-464
    • Heuser, L.S.1    Miller, F.N.2
  • 23
    • 0023161503 scopus 로고
    • Biodistribution of GdCl3 and Gd-DTPA and their influence on proton magnetic relaxation in rat tissues
    • Barnhart JL, Kuhnert N, Bakan DA, Berk RN. Biodistribution of GdCl3 and Gd-DTPA and their influence on proton magnetic relaxation in rat tissues. Magn Reson Imaging 1987;5:221-231.
    • (1987) Magn Reson Imaging , vol.5 , pp. 221-231
    • Barnhart, J.L.1    Kuhnert, N.2    Bakan, D.A.3    Berk, R.N.4
  • 24
    • 0034052192 scopus 로고    scopus 로고
    • Comparison of two blood pool contrast agents for 0.5-T MR angiography: Experimental study in rabbits
    • Clarke SE, Weinmann HJ, Dai E, Lucas AR, Rutt BK. Comparison of two blood pool contrast agents for 0.5-T MR angiography: experimental study in rabbits. Radiology 2000;214:787-794.
    • (2000) Radiology , vol.214 , pp. 787-794
    • Clarke, S.E.1    Weinmann, H.J.2    Dai, E.3    Lucas, A.R.4    Rutt, B.K.5
  • 26
    • 0027158142 scopus 로고
    • Optimization of flip angle for T1 dependent contrast in MRI
    • Pelc NJ. Optimization of flip angle for T1 dependent contrast in MRI. Magn Reson Med 1993;29:695-699.
    • (1993) Magn Reson Med , vol.29 , pp. 695-699
    • Pelc, N.J.1
  • 27
    • 0028065477 scopus 로고
    • Measurement of vascular volume fraction and blood-tissue permeability constants with a pharmacokinetic model: Studies in rat muscle tumors with dynamic Gd-DTPA enhanced MRI
    • Su MY, Jao JC, Nalcioglu O. Measurement of vascular volume fraction and blood-tissue permeability constants with a pharmacokinetic model: studies in rat muscle tumors with dynamic Gd-DTPA enhanced MRI. Magn Reson Med 1994;32:714-724.
    • (1994) Magn Reson Med , vol.32 , pp. 714-724
    • Su, M.Y.1    Jao, J.C.2    Nalcioglu, O.3
  • 28
    • 0027349175 scopus 로고
    • Basic physics of MR contrast agents and maximization of image contrast
    • Hendrick RE, Haacke EM. Basic physics of MR contrast agents and maximization of image contrast. J Magn Reson Imaging 1993;3:137-148.
    • (1993) J Magn Reson Imaging , vol.3 , pp. 137-148
    • Hendrick, R.E.1    Haacke, E.M.2
  • 30
    • 0031397832 scopus 로고    scopus 로고
    • Dynamic imaging of intracranial lesions using fast spin-echo imaging: Differentiation of brain tumors and treatment effects
    • Hazle JD, Jackson EF, Schomer DF, Leeds NE. Dynamic imaging of intracranial lesions using fast spin-echo imaging: differentiation of brain tumors and treatment effects. J Magn Reson Imaging 1997;7:1084-1093.
    • (1997) J Magn Reson Imaging , vol.7 , pp. 1084-1093
    • Hazle, J.D.1    Jackson, E.F.2    Schomer, D.F.3    Leeds, N.E.4
  • 31
    • 0034212763 scopus 로고    scopus 로고
    • Blockade of the epidermal growth factor receptor signaling by a novel tyrosine kinase inhibitor leads to apoptosis of endothelial cells and therapy of human pancreatic carcinoma
    • Bruns CJ, Solorzano CC, Harbison MT, Ozawa S, Tsan R, Fan D, Abbruzzese JL, Traxler P, Buchdunger E, Radinsky R, Fidler IJ. Blockade of the epidermal growth factor receptor signaling by a novel tyrosine kinase inhibitor leads to apoptosis of endothelial cells and therapy of human pancreatic carcinoma. Cancer Res 2000;60:2926-2935.
    • (2000) Cancer Res , vol.60 , pp. 2926-2935
    • Bruns, C.J.1    Solorzano, C.C.2    Harbison, M.T.3    Ozawa, S.4    Tsan, R.5    Fan, D.6    Abbruzzese, J.L.7    Traxler, P.8    Buchdunger, E.9    Radinsky, R.10    Fidler, I.J.11
  • 32
    • 0025192243 scopus 로고
    • Tumorigenicity and metastasis of human breast carcinoma cell lines in nude mice
    • Price JE, Polyzos A, Zhang RD, Daniels LM. Tumorigenicity and metastasis of human breast carcinoma cell lines in nude mice. Cancer Res 1990;50:717-721.
    • (1990) Cancer Res , vol.50 , pp. 717-721
    • Price, J.E.1    Polyzos, A.2    Zhang, R.D.3    Daniels, L.M.4
  • 33
    • 0024994008 scopus 로고
    • Vascular and interstitial barriers to delivery of therapeutic agents in tumors
    • Jain RK. Vascular and interstitial barriers to delivery of therapeutic agents in tumors. Cancer Metastasis Rev 1990;9:253-266.
    • (1990) Cancer Metastasis Rev , vol.9 , pp. 253-266
    • Jain, R.K.1
  • 34
    • 0031924714 scopus 로고    scopus 로고
    • Lectin intravital perfusion studies in tumor-bearing mice: Micrometer-resolution, wide-area mapping of microvascular labeling, distinguishing efficiently and inefficiently perfused microregions in the tumor
    • Debbage PL, Griebel J, Ried M, Gneiting T, DeVries A, Hutzler P. Lectin intravital perfusion studies in tumor-bearing mice: micrometer-resolution, wide-area mapping of microvascular labeling, distinguishing efficiently and inefficiently perfused microregions in the tumor. J Histochem Cytochem 1998;46:627-639.
    • (1998) J Histochem Cytochem , vol.46 , pp. 627-639
    • Debbage, P.L.1    Griebel, J.2    Ried, M.3    Gneiting, T.4    DeVries, A.5    Hutzler, P.6
  • 35
    • 0032875831 scopus 로고    scopus 로고
    • MR microcirculation assessment in cervical cancer: Corrrelations with histomorphological tumor markers and clinical outcome
    • Matr NA, Hawighorst H, Yuh WT, Essig M, Magnetta VA, Knopp MV. MR microcirculation assessment in cervical cancer: corrrelations with histomorphological tumor markers and clinical outcome. J Magn Reson Imaging 1999;10:267-276.
    • (1999) J Magn Reson Imaging , vol.10 , pp. 267-276
    • Matr, N.A.1    Hawighorst, H.2    Yuh, W.T.3    Essig, M.4    Magnetta, V.A.5    Knopp, M.V.6
  • 36
    • 13344269679 scopus 로고    scopus 로고
    • Mammary carcinoma model: Correlation of macromolecular contrast-enhanced MR imaging characterizations of tumor microvasculature and histologic capillary density
    • van Dijke CF, Brasch RC, Roberts TP, Weidner N, Mathur A, Shames DM, Mann JS, Demsar F, Lang P, Schwickert HC. Mammary carcinoma model: correlation of macromolecular contrast-enhanced MR imaging characterizations of tumor microvasculature and histologic capillary density. Radiology 1996;198:813-818.
    • (1996) Radiology , vol.198 , pp. 813-818
    • van Dijke, C.F.1    Brasch, R.C.2    Roberts, T.P.3    Weidner, N.4    Mathur, A.5    Shames, D.M.6    Mann, J.S.7    Demsar, F.8    Lang, P.9    Schwickert, H.C.10
  • 37
    • 0142147988 scopus 로고    scopus 로고
    • Gadopentetate dimeglumine versus ultrasmall superparamagnetic iron oxide for dynamic contrast-enhanced MR imaging of tumor angiogenesis in human colon carcinoma in mice
    • de Lussanet QG, Backes WH, Griffioen AW, van Engelshoven JM, Beets-Tan RG. Gadopentetate dimeglumine versus ultrasmall superparamagnetic iron oxide for dynamic contrast-enhanced MR imaging of tumor angiogenesis in human colon carcinoma in mice. Radiology 2003;229:429-438.
    • (2003) Radiology , vol.229 , pp. 429-438
    • de Lussanet, Q.G.1    Backes, W.H.2    Griffioen, A.W.3    van Engelshoven, J.M.4    Beets-Tan, R.G.5
  • 38
    • 0035019579 scopus 로고    scopus 로고
    • Tumor microvascular characterization using ultrasmall superparamagnetic iron oxide particles (USPIO) in an experimental breast cancer model
    • Turetschek K, Roberts TP, Floyd E, Preda A, Novikov V, Shames DM, Carter WO, Brasch RC. Tumor microvascular characterization using ultrasmall superparamagnetic iron oxide particles (USPIO) in an experimental breast cancer model. J Magn Reson Imaging 2001;13:882-888.
    • (2001) J Magn Reson Imaging , vol.13 , pp. 882-888
    • Turetschek, K.1    Roberts, T.P.2    Floyd, E.3    Preda, A.4    Novikov, V.5    Shames, D.M.6    Carter, W.O.7    Brasch, R.C.8
  • 39
    • 0032950741 scopus 로고    scopus 로고
    • Investigation of longitudinal vascular changes in control and chemotherapy-treated tumors to serve as therapeutic efficacy predictors
    • Su MY, Wang Z, Nalcioglu O. Investigation of longitudinal vascular changes in control and chemotherapy-treated tumors to serve as therapeutic efficacy predictors. J Magn Reson Imaging 1999;9:128-137.
    • (1999) J Magn Reson Imaging , vol.9 , pp. 128-137
    • Su, M.Y.1    Wang, Z.2    Nalcioglu, O.3
  • 41
    • 0034930874 scopus 로고    scopus 로고
    • Understanding why contrast enhancement in dynamic MRI is not reproducible: Illustration with a simple phantom
    • Pabst T, Kenn W, Kaiser WA, Hahn D. Understanding why contrast enhancement in dynamic MRI is not reproducible: illustration with a simple phantom. Breast J 2001;7:166-170.
    • (2001) Breast J , vol.7 , pp. 166-170
    • Pabst, T.1    Kenn, W.2    Kaiser, W.A.3    Hahn, D.4
  • 42
    • 7544225845 scopus 로고    scopus 로고
    • Estimating the arterial input function using two reference tissues in dynamic contrast-enhanced MRI studies: Fundamental concepts and simulations
    • Yang C, Karczmar GS, Medved M, Stadler WM. Estimating the arterial input function using two reference tissues in dynamic contrast-enhanced MRI studies: fundamental concepts and simulations. Magn Reson Med 2004;52:1110-1117.
    • (2004) Magn Reson Med , vol.52 , pp. 1110-1117
    • Yang, C.1    Karczmar, G.S.2    Medved, M.3    Stadler, W.M.4
  • 43


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