HIV-1 envelope protein gp140 binding studies to human brain microvascular endothelial cells

Biochemical and Biophysical Research Communications

Volumn 363, Issue 3, 2007, Pages 466-471

  Mendu, Damodara Rao ^a   Katinger, Hermann ^b   Sodroski, Joseph ^c   Kim, Kwang Sik ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF AGRICULTURAL SCIENCES   (Austria)

^c DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

Brain microvascular endothelial cells; HIV 1 envelope protein; Homologous competition binding studies; Optimal binding conditions

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CXCR4; DIMER; GLYCOPROTEIN GP 140; MONOMER; OLIGOMER; STROMAL CELL DERIVED FACTOR 1; VIRUS ENVELOPE PROTEIN;

ARTICLE; BINDING ASSAY; BINDING KINETICS; BINDING SITE; BRAIN BLOOD VESSEL; BRAIN INFECTION; CELL ACTIVATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DEMENTIA; DRUG DESIGN; ENDOTHELIUM CELL; ENVIRONMENTAL TEMPERATURE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; ISOTOPE LABELING; MICROVASCULATURE; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; RADIOASSAY; RECEPTOR BINDING; SCATCHARD PLOT; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS; SURFACE PROPERTY; TARGET CELL; TEMPERATURE;

ANTIBODIES; ANTIGENS, CD4; BRAIN; CELLS, CULTURED; DIMERIZATION; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENDOTHELIAL CELLS; ENV GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; HIV ENVELOPE PROTEIN GP41; HUMANS; HYDROGEN-ION CONCENTRATION; KINETICS; PROTEIN BINDING; RADIOLIGAND ASSAY; RECEPTORS, CXCR4; TEMPERATURE;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 34948865244     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.08.121     Document Type: Article

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