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Volumn 117, Issue 5-6, 2007, Pages 247-251

Clinical significance of interleukin-6 (IL-6) as a prognostic factor of cancer disease;Znaczenie kliniczne interleukiny 6 (IL-6) jako czynnika rokowniczego w chorobie nowotworowej

Author keywords

Cancer; Interleukin 6

Indexed keywords

INTERLEUKIN 6; INTERLEUKIN 6 ANTIBODY;

EID: 34948823889     PISSN: 00323772     EISSN: None     Source Type: Journal    
DOI: 10.20452/pamw.144     Document Type: Review
Times cited : (56)

References (40)
  • 1
    • 0035367819 scopus 로고    scopus 로고
    • Signaling by type I and II cytokine receptors: Ten years after
    • Gadina M, Hilton D, Johnson JA, et al. Signaling by type I and II cytokine receptors: ten years after. Curr Opin Immunol. 2001; 13: 363-373.
    • (2001) Curr Opin Immunol , vol.13 , pp. 363-373
    • Gadina, M.1    Hilton, D.2    Johnson, J.A.3
  • 2
    • 33748117796 scopus 로고    scopus 로고
    • Interieukin-6: Discovery of pleiotropic cytokine
    • Kishimoto T. Interieukin-6: discovery of pleiotropic cytokine. Arthiritis Res Ther. 2006; 8 (Suppl 2): S2.
    • (2006) Arthiritis Res Ther , vol.8 , Issue.SUPPL. 2
    • Kishimoto, T.1
  • 3
    • 23944441266 scopus 로고    scopus 로고
    • Interleukin-6 regulation of prostate cancer cell growth
    • Culig Z, Steiner H, Bartsch G, et al. Interleukin-6 regulation of prostate cancer cell growth. J Cell Biochem. 2005; 95: 497-505.
    • (2005) J Cell Biochem , vol.95 , pp. 497-505
    • Culig, Z.1    Steiner, H.2    Bartsch, G.3
  • 4
    • 0037455841 scopus 로고    scopus 로고
    • Circulating interleukin-6 predictors survival in patients with metastatic breast cancer
    • Salgado R, Junius S, Benoy I, et al. Circulating interleukin-6 predictors survival in patients with metastatic breast cancer. Int J Cancer. 2003; 103: 642-646.
    • (2003) Int J Cancer , vol.103 , pp. 642-646
    • Salgado, R.1    Junius, S.2    Benoy, I.3
  • 5
    • 85080587844 scopus 로고    scopus 로고
    • Golab J, Jakobisiak M, Lasek W, et al. Cytokiny. Immunologia. Warszawa, Wyd Nauk PWN, 2002; 15: 198-205.
    • Golab J, Jakobisiak M, Lasek W, et al. Cytokiny. Immunologia. Warszawa, Wyd Nauk PWN, 2002; 15: 198-205.
  • 6
    • 0039548942 scopus 로고
    • Biologia i farmakologia cytokin
    • Robak T. Biologia i farmakologia cytokin. Warszawa, Wyd Nauk PWN, 1995; 9: 122-133.
    • (1995) Warszawa, Wyd Nauk PWN , vol.9 , pp. 122-133
    • Robak, T.1
  • 8
    • 33646228126 scopus 로고    scopus 로고
    • Interleukin-6 (IL-6) trans-signaling in chronic inflammation and cancer
    • Scheller J, Ohnesorge N, Rose-John S, et al. Interleukin-6 (IL-6) trans-signaling in chronic inflammation and cancer. Scand J Immunonol. 2006; 63: 321-329.
    • (2006) Scand J Immunonol , vol.63 , pp. 321-329
    • Scheller, J.1    Ohnesorge, N.2    Rose-John, S.3
  • 9
    • 0036369821 scopus 로고    scopus 로고
    • Circulating levels of thrombopoietic and inflammatory cytokines in patients with acute myeloblasts leukemia and myelodysplastic syndrome
    • Hsu HC, Lee YM, Tsai WH, et al. Circulating levels of thrombopoietic and inflammatory cytokines in patients with acute myeloblasts leukemia and myelodysplastic syndrome. Oncology. 2002; 63: 64-69.
    • (2002) Oncology , vol.63 , pp. 64-69
    • Hsu, H.C.1    Lee, Y.M.2    Tsai, W.H.3
  • 10
    • 2642579084 scopus 로고    scopus 로고
    • Interleukin-6 increases vascular endothelial growth factor and angiogenesis in gastric cercinoma
    • Huang SP, Wu MS, Shun CT, et al. Interleukin-6 increases vascular endothelial growth factor and angiogenesis in gastric cercinoma. J Biomed Sci. 2004; 11: 517-527.
    • (2004) J Biomed Sci , vol.11 , pp. 517-527
    • Huang, S.P.1    Wu, M.S.2    Shun, C.T.3
  • 11
    • 0026760711 scopus 로고
    • Interieukin-6 increases carcinoembryonic antigen and histocompatibility leukocyte antigen expression on the surface of human colorectal carcinoma cells
    • Ulimann CD, Schlom J, Greiner JW. Interieukin-6 increases carcinoembryonic antigen and histocompatibility leukocyte antigen expression on the surface of human colorectal carcinoma cells. J Immunother. 1992; 12: 231-241.
    • (1992) J Immunother , vol.12 , pp. 231-241
    • Ulimann, C.D.1    Schlom, J.2    Greiner, J.W.3
  • 12
    • 33750102235 scopus 로고    scopus 로고
    • Tocilizumab: Blockade of interleukin-6 signaling pathway as a therapeutic strategy for inflammatory disorders
    • Paul-Pletzer K. Tocilizumab: Blockade of interleukin-6 signaling pathway as a therapeutic strategy for inflammatory disorders. Drugs Today. 2006; 42: 559-576.
    • (2006) Drugs Today , vol.42 , pp. 559-576
    • Paul-Pletzer, K.1
  • 13
    • 33748092926 scopus 로고    scopus 로고
    • Interleukin-6 and rheumatic diseases
    • Lipsky PE. Interleukin-6 and rheumatic diseases. Arthritis Res Ther. 2006; 2: S4.
    • (2006) Arthritis Res Ther , vol.2
    • Lipsky, P.E.1
  • 14
    • 0026469909 scopus 로고
    • Marked increase in plasma interleukin-6 in burn patients
    • Ueyama M, Maruyama I, Osame M. Marked increase in plasma interleukin-6 in burn patients. J Lab Clin Med. 1992; 120: 693-698.
    • (1992) J Lab Clin Med , vol.120 , pp. 693-698
    • Ueyama, M.1    Maruyama, I.2    Osame, M.3
  • 15
    • 33845928183 scopus 로고    scopus 로고
    • Procalcitonin, lipopolysaccharide- binding protein, interleukin-6 and C-reactive protein in community-acquired infections and sepsis: A prospective study
    • Gaini S, Koldkjaer OG, Pedersen C. Procalcitonin, lipopolysaccharide- binding protein, interleukin-6 and C-reactive protein in community-acquired infections and sepsis: a prospective study. Crit Care. 2006; 10: R53.
    • (2006) Crit Care , vol.10
    • Gaini, S.1    Koldkjaer, O.G.2    Pedersen, C.3
  • 16
    • 0032917584 scopus 로고    scopus 로고
    • Proinflammatory cytokines in early assessment of the prognosis of acute pancreatitis
    • Chen CC, Wang SS, Lee FY, et al. Proinflammatory cytokines in early assessment of the prognosis of acute pancreatitis. Am J Gastroenterol. 1999; 94: 213-218.
    • (1999) Am J Gastroenterol , vol.94 , pp. 213-218
    • Chen, C.C.1    Wang, S.S.2    Lee, F.Y.3
  • 17
    • 33645087937 scopus 로고    scopus 로고
    • Evaluation of C-reactive protein, interleukin-6, and procalcitonin levels in allogeneic hematopoietic stem cell recipients
    • Pihusch M, Pihusch R, Fraunberger P, et al. Evaluation of C-reactive protein, interleukin-6, and procalcitonin levels in allogeneic hematopoietic stem cell recipients. Eur J Haematol. 2006; 76: 93-101.
    • (2006) Eur J Haematol , vol.76 , pp. 93-101
    • Pihusch, M.1    Pihusch, R.2    Fraunberger, P.3
  • 18
    • 0025014780 scopus 로고
    • Infection with HIV is associated with elevated IL-6 levels and production
    • Breen EC, Rezai AR, Nakajima K, et al. Infection with HIV is associated with elevated IL-6 levels and production. J Immunol. 1990; 144: 480-484.
    • (1990) J Immunol , vol.144 , pp. 480-484
    • Breen, E.C.1    Rezai, A.R.2    Nakajima, K.3
  • 19
    • 26244434315 scopus 로고    scopus 로고
    • Differentiation-dependent expression and myogenic action of interleukin-6 in human colon carcinoma cells: Relevance for tumor progression
    • Brozek W, Bises G, Girsch T, et al. Differentiation-dependent expression and myogenic action of interleukin-6 in human colon carcinoma cells: relevance for tumor progression. Eur J Cancer. 2005; 41: 2347-2354.
    • (2005) Eur J Cancer , vol.41 , pp. 2347-2354
    • Brozek, W.1    Bises, G.2    Girsch, T.3
  • 20
    • 20444467988 scopus 로고    scopus 로고
    • High serum levels of interleukin-6 in endometrial carcinoma are associated with uterine serous papillary histology, a highly aggressive and chemotherapy-resistant variant of endometrial cancer
    • Bellone S, Watts K, Cane S, et al. High serum levels of interleukin-6 in endometrial carcinoma are associated with uterine serous papillary histology, a highly aggressive and chemotherapy-resistant variant of endometrial cancer. Gynecol Oncol. 2005; 98: 92-98.
    • (2005) Gynecol Oncol , vol.98 , pp. 92-98
    • Bellone, S.1    Watts, K.2    Cane, S.3
  • 21
    • 2942616855 scopus 로고    scopus 로고
    • Serum interleukin-6 levels correlate with malnutrition and survival in patients with advanced non-small cell lung cancer
    • Songur N, Kuru B, Kalkan F, et al. Serum interleukin-6 levels correlate with malnutrition and survival in patients with advanced non-small cell lung cancer. Tumor. 2004; 90: 196-200.
    • (2004) Tumor , vol.90 , pp. 196-200
    • Songur, N.1    Kuru, B.2    Kalkan, F.3
  • 22
    • 0034106055 scopus 로고    scopus 로고
    • Interleukin-6 blood level is associated with circulating carcinoembryonic antigen and prognosis in patients with colorectal cancer
    • Belluco C, Nitti D, Frantz M, et al. Interleukin-6 blood level is associated with circulating carcinoembryonic antigen and prognosis in patients with colorectal cancer. Ann Surg Oncol. 2000; 7: 133-138.
    • (2000) Ann Surg Oncol , vol.7 , pp. 133-138
    • Belluco, C.1    Nitti, D.2    Frantz, M.3
  • 23
    • 85080598128 scopus 로고    scopus 로고
    • Interleukin-6, interieukin-10, and vascular ednothelial growth factor in metastatic renal cell carcinoma: Prognostic value of interieukin-6
    • Negrier S, Perol O, Menetrier-Caux C, et al. Interleukin-6, interieukin-10, and vascular ednothelial growth factor in metastatic renal cell carcinoma: prognostic value of interieukin-6. J Clin Oncol. 2005; 23: 1044-1045.
    • (2005) J Clin Oncol , vol.23 , pp. 1044-1045
    • Negrier, S.1    Perol, O.2    Menetrier-Caux, C.3
  • 24
    • 0035459901 scopus 로고    scopus 로고
    • Changes of serum IL-6 and CRP after chemiotherapy in patients with ovarian carcinoma
    • Zakrzewska I, Pozański J. Changes of serum IL-6 and CRP after chemiotherapy in patients with ovarian carcinoma. Pol Merk Lek. 2001; 11: 210-213.
    • (2001) Pol Merk Lek , vol.11 , pp. 210-213
    • Zakrzewska, I.1    Pozański, J.2
  • 25
    • 22144438698 scopus 로고    scopus 로고
    • IL-6, its receptors and its relationship with bcl-2 and bax proteins in infiltrating and in situ human breast carcinoma
    • Garcia-Tunon I, Ricote M, Ruiz A, et al. IL-6, its receptors and its relationship with bcl-2 and bax proteins in infiltrating and in situ human breast carcinoma. Histopathology. 2005; 47: 82-89.
    • (2005) Histopathology , vol.47 , pp. 82-89
    • Garcia-Tunon, I.1    Ricote, M.2    Ruiz, A.3
  • 26
    • 24644461106 scopus 로고    scopus 로고
    • Clinical significance of serum cytokine measurements in untreated colorectal cancer patients: Soluble tumor necrosis factor receptor type I - an independent prognostic factor
    • Kaminska J, Nowacki MP, Kowalska M, et al. Clinical significance of serum cytokine measurements in untreated colorectal cancer patients: soluble tumor necrosis factor receptor type I - an independent prognostic factor. Tumor Biol. 2005; 26: 186-194.
    • (2005) Tumor Biol , vol.26 , pp. 186-194
    • Kaminska, J.1    Nowacki, M.P.2    Kowalska, M.3
  • 27
    • 17144401909 scopus 로고    scopus 로고
    • Serum IL-6, TNFalpha and CRP levels in Geek colorectal cancer patients: Prognostic implications
    • Nikiteas NI, Tzanakis N, Gazouli M. Serum IL-6, TNFalpha and CRP levels in Geek colorectal cancer patients: prognostic implications. World J Gastroenterol. 2005; 11: 1639-1643.
    • (2005) World J Gastroenterol , vol.11 , pp. 1639-1643
    • Nikiteas, N.I.1    Tzanakis, N.2    Gazouli, M.3
  • 29
    • 0033036097 scopus 로고    scopus 로고
    • Serum interleukin-6 levels correlate to tumor progression and prognosis in metastatic breast carcinoma
    • Zhang G, Adachi I. Serum interleukin-6 levels correlate to tumor progression and prognosis in metastatic breast carcinoma. Anticancer Res. 1999; 19: 1427-1432.
    • (1999) Anticancer Res , vol.19 , pp. 1427-1432
    • Zhang, G.1    Adachi, I.2
  • 30
    • 34948831956 scopus 로고    scopus 로고
    • Serum level of the angiogenetic factors: IL-6 and IL-8 in patients with gastric cancer
    • Wallner G, Ciechański A, Dabrowski A, et al. Serum level of the angiogenetic factors: IL-6 and IL-8 in patients with gastric cancer. Asian J. Surg. 2002; 26: 132.
    • (2002) Asian J. Surg , vol.26 , pp. 132
    • Wallner, G.1    Ciechański, A.2    Dabrowski, A.3
  • 31
    • 18544364182 scopus 로고    scopus 로고
    • Clinical significance of interleukin-6 (IL-6) in the spread of gastric cancer: Role of IL-6 as a prognostic factor
    • Ashizawa T, Okada R, Suzuki Y, et al. Clinical significance of interleukin-6 (IL-6) in the spread of gastric cancer: role of IL-6 as a prognostic factor. Gastric Cancer. 2005; 8: 124-131.
    • (2005) Gastric Cancer , vol.8 , pp. 124-131
    • Ashizawa, T.1    Okada, R.2    Suzuki, Y.3
  • 32
    • 0030061195 scopus 로고    scopus 로고
    • Serum interleukin-6 reflect disease status of gastric cancer
    • Wu CW, Wang SR, Chao MF, et al. Serum interleukin-6 reflect disease status of gastric cancer. Am J Gastroenterol. 1996; 91: 1417-1422.
    • (1996) Am J Gastroenterol , vol.91 , pp. 1417-1422
    • Wu, C.W.1    Wang, S.R.2    Chao, M.F.3
  • 33
    • 33746736234 scopus 로고    scopus 로고
    • Serum interleukin-6 levels in patients with gastric MALT lymphoma compared to gastric and pancreatic cancer
    • Bartsch R, Woehrer S, Raderer M, et al. Serum interleukin-6 levels in patients with gastric MALT lymphoma compared to gastric and pancreatic cancer. Anticancer Res. 2006; 26: 3187-3190.
    • (2006) Anticancer Res , vol.26 , pp. 3187-3190
    • Bartsch, R.1    Woehrer, S.2    Raderer, M.3
  • 34
    • 0031606207 scopus 로고    scopus 로고
    • Elevated serum interieukin 6 levels in patients with pancreatic cancer
    • Okada S, Okusaka T, Ishii H. Elevated serum interieukin 6 levels in patients with pancreatic cancer. Jpn J Gin Oncol. 1998; 28: 12-15.
    • (1998) Jpn J Gin Oncol , vol.28 , pp. 12-15
    • Okada, S.1    Okusaka, T.2    Ishii, H.3
  • 35
    • 0035153882 scopus 로고    scopus 로고
    • Interleukin-6 inhibits radiation induced apoptosis in pancreatic cancer cell
    • Miyamoto Y, Hosotani R, Doi R, et al. Interleukin-6 inhibits radiation induced apoptosis in pancreatic cancer cell. Anticancer Res. 2001; 21: 2449-2456.
    • (2001) Anticancer Res , vol.21 , pp. 2449-2456
    • Miyamoto, Y.1    Hosotani, R.2    Doi, R.3
  • 36
    • 20144377623 scopus 로고    scopus 로고
    • Serum IL-10 and IL-6 levels at diagnosis as independent predictors of outcome in non-Hodgkin's lymphoma
    • El-Far M, Founda M, Yahya R, et al. Serum IL-10 and IL-6 levels at diagnosis as independent predictors of outcome in non-Hodgkin's lymphoma. J Physiol Biochem. 2004; 60: 253-258.
    • (2004) J Physiol Biochem , vol.60 , pp. 253-258
    • El-Far, M.1    Founda, M.2    Yahya, R.3
  • 37
    • 0036720519 scopus 로고    scopus 로고
    • Prognostic value of plasma interieukin-6 levels in patients with chronic lymphocytic leukemia
    • Lai R, O'Brien S, Maushouri T, et al. Prognostic value of plasma interieukin-6 levels in patients with chronic lymphocytic leukemia. Cancer. 2002; 95: 1071-1075.
    • (2002) Cancer , vol.95 , pp. 1071-1075
    • Lai, R.1    O'Brien, S.2    Maushouri, T.3
  • 38
    • 34948844434 scopus 로고    scopus 로고
    • The significance of IGF-1, VEGF, IL-6 in multiple myeloma progression. [Abstract]
    • Guo YQ, Chen SL. The significance of IGF-1, VEGF, IL-6 in multiple myeloma progression. [Abstract]. Zhonghua Xue Ye Xue Za Zhi. 2006; 27: 231-234.
    • (2006) Zhonghua Xue Ye Xue Za Zhi , vol.27 , pp. 231-234
    • Guo, Y.Q.1    Chen, S.L.2
  • 39
    • 33746889019 scopus 로고    scopus 로고
    • Multiple myeloma and B cell lymphoma. Investigation of IL-6, IL-6 receptor antagonist (IL-6RA), and GP130 antagonist (GP130A) using various parameters in an in vitro model
    • Kovacs E. Multiple myeloma and B cell lymphoma. Investigation of IL-6, IL-6 receptor antagonist (IL-6RA), and GP130 antagonist (GP130A) using various parameters in an in vitro model. Scientific World Journal. 2006; 6: 888-898.
    • (2006) Scientific World Journal , vol.6 , pp. 888-898
    • Kovacs, E.1
  • 40
    • 33750955637 scopus 로고    scopus 로고
    • Clinical impact of cachexia on survival and outcome of cancer patients
    • Dimitriu C, Martignoni ME, Bachmann J, et al. Clinical impact of cachexia on survival and outcome of cancer patients. Rom J Intern Med. 2005; 43: 173-185.
    • (2005) Rom J Intern Med , vol.43 , pp. 173-185
    • Dimitriu, C.1    Martignoni, M.E.2    Bachmann, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.