Differentiation-dependent expression and mitogenic action of interleukin-6 in human colon carcinoma cells: Relevance for tumour progression

European Journal of Cancer

Volumn 41, Issue 15, 2005, Pages 2347-2354

  Brozek, Wolfgang ^a   Bises, Giovanna ^a   Girsch, Thomas ^a   Cross, Heide S ^a   Kaiser, Hans E ^a   Peterlik, Meinrad ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

Caco 2 cells; COGA cells; Colon cancer; Gp130; IL 6 gene polymorphisms; IL 6 receptor ; Interleukin 1; Proliferation; Prostaglandins; STAT3

Indexed keywords

INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR; MESSENGER RNA; STAT3 PROTEIN;

ARTICLE; CANCER CELL; CANCER GROWTH; CELL DIFFERENTIATION; CELL STIMULATION; COLON CARCINOMA; CONTROLLED STUDY; CYTOKINE RELEASE; HUMAN; HUMAN CELL; MITOGENESIS; MOLECULAR CLONING; PARACRINE SIGNALING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RNA ANALYSIS; RNA TRANSLATION; SIGNAL TRANSDUCTION;

ADENOCARCINOMA; CELL DIVISION; CELL TRANSFORMATION, NEOPLASTIC; COLON; COLONIC NEOPLASMS; CYTOKINES; DISEASE PROGRESSION; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-6; MITOGENS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 26244434315     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejca.2005.07.014     Document Type: Article

References (29)

1. T. Hirano Interleukin 6 and its receptor: ten years later Int Rev Immunol 16 1998 249 284
2. S.K. Ardestani, P. Inserra, and D. Solkoff The role of cytokines and chemokines on tumor progression: a review Cancer Detect Prev 23 1999 215 225
3. K. Shirota, L. LeDuy, and S.Y. Yuan Interleukin-6 and its receptor are expressed in human intestinal epithelial cells Virchows Arch B Cell Pathol Incl Mol Pathol 58 1990 303 308
4. H. Komoda, Y. Tanaka, and M. Honda Interleukin-6 levels in colorectal cancer tissues World J Surg 22 1998 895 898
5. T. Kinoshita, H. Ito, and C. Miki Serum interleukin-6 level reflects the tumor proliferative activity in patients with colorectal carcinoma Cancer 85 1999 2526 2531
6. D. Piancatelli, P. Romano, and P. Sebastiani Local expression of cytokines in human colorectal carcinoma: evidence of specific interleukin-6 gene expression J Immunother 22 1999 25 32
7. M.R. Schneider, A. Hoeflich, and J.R. Fischer Interleukin-6 stimulates clonogenic growth of primary and metastatic human colon carcinoma cells Cancer Lett 151 2000 31 38
8. K. Matsuo, M. Oka, and K. Murase Expression of interleukin 6 and its receptor in human gastric and colorectal cancers J Int Med Res 31 2003 69 75
9. H.C. Jung, L. Eckmann, and S.K. Yang A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion J Clin Invest 95 1995 55 65
10. A.A. Parikh, A.L. Salzman, and J.E. Fischer Interleukin-1 beta and interferon-gamma regulate interleukin-6 production in cultured human intestinal epithelial cells Shock 8 1997 249 255
11. S.J. Vitkus, S.A. Hanifin, and D.W. McGee Factors affecting Caco-2 intestinal epithelial cell interleukin-6 secretion In Vitro Cell Dev Biol Anim 34 1998 660 664
12. H. Yuan, F.J. Liddle, and S. Mahajan IL-6-induced survival of colorectal carcinoma cells is inhibited by butyrate through down-regulation of the IL-6 receptor Carcinogenesis 25 2004 2247 2255
13. L.H. Sobin, and C. Wittekind TNM classification of malignant tumors 5th ed. 1997 Wiley New York
14. B. Vecsey-Semjen, K.F. Becker, and A. Sinski Novel colon cancer cell lines leading to better understanding of the diversity of respective primary cancers Oncogene 21 2002 4646 4662
15. H. Hofer, G. Ho, and M. Peterlik Biological effects of 1alpha-hyroxy-and 1beta-(hydroxymethyl)-vitamin D compounds relevant for potential colorectal cancer therapy J Pharmacol Exp Ther 291 1999 450 455
16. R. Stierum, M. Gaspari, and Y. Dommels Proteome analysis reveals novel proteins associated with proliferation and differentiation of the colorectal cancer cell line Caco-2 Biochim Biophys Acta 1650 2003 73 91
17. T.R. Faruqi, D. Gomez, and X.R. Bustelo Rac1 mediates STAT3 activation by autocrine IL-6 Proc Natl Acad Sci USA 98 2001 9014 9019
18. H.F. Chen, C.Y. Lin, and K.H. Chao Defective production of interleukin-11 by decidua and chorionic villi in human anembryonic pregnancy J Clin Endocrinol Metab 87 2002 2320 2328
19. H. Shiratsuchi, T. Saito, and A. Sakamoto Mutation analysis of human cytokeratin 8 gene in malignant rhabdoid tumor: a possible association with intracytoplasmic inclusion body formation Mod Pathol 15 2002 146 153
20. E. Fosslien Molecular pathology of cyclooxygenase-2 in neoplasia Ann Clin Lab Sci 30 2000 3 21
21. L.A. Hefler, C. Grimm, and S. Ackermann An interleukin-6 gene promoter polymorphism influences the biological phenotype of ovarian cancer Cancer Res 63 2003 3066 3068
22. D. Fishman, G. Faulds, and R. Jeffery The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis J Clin Invest 102 1998 1369 1376
23. C. Belluco, F. Olivieri, and M. Bonafe -174 G > C polymorphism of interleukin 6 gene promoter affects interleukin 6 serum level in patients with colorectal cancer Clin Cancer Res 9 2003 2173 2176
24. C.F. Terry, V. Loukaci, and F.R. Green Cooperative influence of genetic polymorphisms on interleukin 6 transcriptional regulation J Biol Chem 275 2000 18138 18144
25. C. Becker, M.C. Fantini, and C. Schramm TGF-beta suppresses tumor progression in colon cancer by inhibition of IL-6 trans-signaling Immunity 21 2004 491 501
26. N.C. Tebbutt, A.S. Giraud, and M. Inglese Reciprocal regulation of gastrointestinal homeostasis by SHP2 and STAT-mediated trefoil gene activation in gp130 mutant mice Nat Med 8 2002 1089 1097
27. S. Wang, and B.M. Evers Caco-2 cell differentiation is associated with a decrease in stat protein levels and binding J Gastrointest Surg 3 1999 200 207
28. N.M. Morton, V. Emilsson, and Y.L. Liu Leptin action in intestinal cells J Biol Chem 273 1998 26194 26201
29. E. Mizoguchi, A. Mizoguchi, and H. Takedatsu Role of tumor necrosis factor receptor 2 (TNFR2) in colonic epithelial hyperplasia and chronic intestinal inflammation in mice Gastroenterology 122 2002 134 144