The state of play in the battle against antimicrobial resistance: A general practitioner perspective

Journal of Antimicrobial Chemotherapy

Volumn 60, Issue SUPPL. 1, 2007, Pages

  Fleming, Douglas M ^a  

^a ROYAL COLLEGE OF GENERAL PRACTITIONERS   (United Kingdom)

Author keywords

Food chain; Prescribing; Surveillance

Indexed keywords

ANTIINFECTIVE AGENT;

ARTICLE; BACTERIAL INFECTION; DRUG UTILIZATION; GENERAL PRACTICE; HUMAN; STANDARD; UNITED KINGDOM;

ANTI-BACTERIAL AGENTS; BACTERIAL INFECTIONS; DRUG UTILIZATION; FAMILY PRACTICE; GREAT BRITAIN; HUMANS;

EID: 34948821840     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkm157     Document Type: Article

References (56)

1. Standing Medical Advisory Committee Sub-Group on Antimicrobial Resistance 1998. The Path of Least Resistance. http://www. advisorybodies.doh.gov.uk/smac1.htm (12 February 2007, date last accessed).
2. Inter-Agency Report 2007. Overview of Antimicrobial Usage and Bacterial Resistance in Selected Human and Animal Pathogens in the UK 2004 Report. http://www.vmd.gov.uk/Publications/Antibiotic/ Antipubs.htm.
3. DEFRA (2006). Quarterly supplies and totals for domestic usage of meat in the United Kingdom. http://statistics.defra.gov.uk/esg/statnot/ qlymtpn.pdf (23 February 2007, date last accessed).
4. Veterinary Medicine Directorate (2006). Sales of antimicrobial products authorised for use as veterinary medicines, antiprotozoals, antifungals, growth promotors and coccidiostats in the UK in 2005. http://www.vmd.gov.uk/Publications/Antibiotic/salesanti05.pdf (23 February 2007, date last accessed).
5. Tan TY, McNulty C, Charlett A et al. Laboratory antibiotic susceptibility reporting and antibiotic prescribing in general practice. J Antimicrob Chemother 2003; 51: 379-84.
6. Finch R. Bacterial resistance-the clinical challenge. Clin Microbiol Infect 2002; 8 Suppl 3: 21-32.
7. Hay AD, Thomas M, Montgomery A et al. The relationship between primary care antibiotic prescribing and bacterial resistance in adults in the community: a controlled observational study using individual patient data. J Antimicrob Chemother 2005; 56: 146-53.
8. Magee JT, Heginbothom ML, Mason BW. Finding a strategy: the case for co-operative research on resistance epidemiology. J Antimicrob Chemother 2005; 55: 628-33.
9. Priest P, Yudkin P, McNulty C et al. Antibacterial prescribing and antibacterial resistance in English general practice: cross sectional study. BMJ 2001; 323: 1037-41.
10. Cars O, Molstad S, Melander A. Variation in antibiotic use in the European Union. Lancet 2001; 357: 1851-3.
11. Goossens H, Ferech M, Vander Stichele R et al. Outpatient antibiotic use in Europe and association with resistance: a cross-national database study. Lancet 2005; 365: 579-87.
12. Magee JT, Pritchard EL, Fitzgerald KA et al. Antibiotic prescribing and antibiotic resistance in community practice: retrospective study, 1996-8. BMJ 1999; 319: 1239-40.
13. McNulty CA, Bowen J, Clark G et al. How should general practitioners investigate suspected urinary tract infection? Variations in laboratory-confirmed bacteriuria in South West England. Commun Dis Public Health 2004; 7: 220-6.
14. Secretary of State for Health. Resistance to Antibiotics and Other Antimicrobial Agents. London: The Stationery Office, 1998.
15. Smellie WS, Clark G, McNulty CA. Inequalities of primary care microbiology testing between hospital catchment areas. J Clin Pathol 2003; 56: 933-6.
16. Donnan PT, Wei L, Steinke DT et al. Presence of bacteriuria caused by trimethoprim resistant bacteria in patients prescribed antibiotics: multilevel model with practice and individual patient data. BMJ 2004; 328: 1297.
17. MacKenzie FM, Bruce J, Van Looveren M et al. Antimicrobial susceptibility testing in European hospitals: report from the ARPAC study. Clin Microbiol Infect 2006; 12: 1185-92.
18. McNulty CA, Richards J, Livermore DM et al. Clinical relevance of laboratory-reported antibiotic resistance in acute uncomplicated urinary tract infection in primary care. J Antimicrob Chemother 2006; 58: 1000-8.
19. Tan TY, McNulty CA. Survey of public health laboratory protocols for reporting the antibiotic susceptibility of urinary isolates submitted from general practice. Commun Dis Public Health 2002; 5: 33-7.
20. Woodhead M, Fleming D, Wise R. Antibiotics, resistance, and clinical outcomes. BMJ 2004; 328: 1270-1.
21. Keen J. The NHS programme for information technology. BMJ 2006; 333: 3-4.
22. Norheim OF. Soft paternalism and the ethics of shared electronic patient records. BMJ 2006; 333: 2-3.
23. Watson N. Patients should have to opt out of national electronic care records: FOR. BMJ 2006; 333: 39-40.
24. Fleming DM. Wanted: social contract for practice of medicine. Ethical framework for using medical records is needed. BMJ 2001; 323: 930.
25. Smellie WS, Forth J, Sundar S et al. Best practice in primary care pathology: review 4. J Clin Pathol 2006; 59: 893-902.
26. Woodhead M. Community-acquired pneumonia guidelines: much guidance, but not much evidence. Eur Respir J 2002; 20: 1-3.
27. Finch RG, Low DE. A critical assessment of published guidelines and other decision-support systems for the antibiotic treatment of community-acquired respiratory tract infections. Clin Microbiol Infect 2002; 8: 69-91.
28. Fleming DM, Zambon M, Bartelds AI et al. The duration and magnitude of influenza epidemics: a study of surveillance data from sentinel general practices in England, Wales and the Netherlands. Eur J Epidemiol 1999; 15: 467-73.
29. NICE (2003). Flu treatment-zanamivir, amantadine and oseltamivir: guidance. National Institute for Clinical Excellence, London.
30. Fleming DM, Cross KW, Crombie DL et al. Respiratory illness and mortality in England and Wales. A study of the relationships between weekly data for the incidence of respiratory disease presenting to general practitioners, and registered deaths. Eur J Epidemiol 1993; 9: 571-6.
31. Fleming DM, Elliot AJ, Cross KW. Morbidity profiles of patients consulting during influenza and respiratory syncytial virus active periods. Epidemiol Infect 2007; doi:10.1017/S0950268807007881.
32. Fleming DM, Elliot AJ, Nguyen-van Tam JS et al. (January 2005). A Winter's Tale: coming to terms with winter respiratory illnesses. Health Protection Agency, London.
33. Pitkaranta A, Jero J, Arruda E et al. Polymerase chain reactionbased detection of rhinovirus, respiratory syncytial virus, and coronavirus in otitis media with effusion. J Pediatr 1998; 133: 390-4.
34. Otters HB, van der Wouden JC, Schellevis FG et al. Trends in prescribing antibiotics for children in Dutch general practice. J Antimicrob Chemother 2004; 53: 361-6.
35. Steinman MA, Gonzales R, Linder JA et al. Changing use of antibiotics in community-based outpatient practice, 1991-1999. Ann Intern Med 2003; 138: 525-33.
36. Finch RG, Metlay JP, Davey PG et al. Educational interventions to improve antibiotic use in the community: report from the International Forum on Antibiotic Resistance (IFAR) colloquium, 2002. Lancet Infect Dis 2004; 4: 44-53.
37. Goossens H, Guillemot D, Ferech M et al. National campaigns to improve antibiotic use. Eur J Clin Pharmacol 2006; 62: 373-9.
38. Williamson I, Benge S, Mullee M et al. Consultations for middle ear disease, antibiotic prescribing and risk factors for reattendance: a case-linked cohort study. Br J Gen Pract 2006; 56: 170-5.
39. Arnold SR, Straus SE. Interventions to improve antibiotic prescribing practices in ambulatory care. Cochrane Database Syst Rev 2005; CD003539.
40. Spurling GK, Del Mar CB, Dooley L et al. Delayed antibiotics for symptoms and complications of respiratory infections. Cochrane Database Syst Rev 2004; CD004417.
41. Rose PW, Harnden A, Brueggemann AB et al. Chloramphenicol treatment for acute infective conjunctivitis in children in primary care: a randomised double-blind placebo-controlled trial. Lancet 2005; 366: 37-43.
42. Everitt HA, Little PS, Smith PW. A randomised controlled trial of management strategies for acute infective conjunctivitis in general practice. BMJ 2006; 333: 321.
43. Little P. Delayed prescribing-a sensible approach to the management of acute otitis media. JAMA 2006; 296: 1290-1.
44. Crombie DL, Fleming DM. Practice activity analysis. The SE Thames experiment. Occas Pap 41 R Coll Gen Pract 1988; 19-20.
45. McNulty CA, Kane A, Foy CJ et al. Primary care workshops can reduce and rationalize antibiotic prescribing. J Antimicrob Chemother 2000; 46: 493-9.
46. Rautakorpi UM, Huikko S, Honkanen P et al. The Antimicrobial Treatment Strategies (MIKSTRA) program: a 5-year follow-up of infection-specific antibiotic use in primary health care and the effect of implementation of treatment guidelines. Clin Infect Dis 2006; 42: 1221-30.
47. Ashworth M, Latinovic R, Charlton J et al. Why has antibiotic prescribing for respiratory illness declined in primary care? A longitudinal study using the General Practice Research Database. J Public Health (Oxford) 2004; 26: 268-74.
48. Charles J, Pan Y, Britt H. Trends in childhood illness and treatment in Australian general practice, 1971-2001. Med J Aust 2004; 180: 216-9.
49. Fleming DM, Ross AM, Cross KW et al. The reducing incidence of respiratory tract infection and its relation to antibiotic prescribing. Br J Gen Pract 2003; 53: 778-83.
50. Fleming DM, Elliot AJ, Kendall H. Skin infections and antibiotic prescribing: a comparison of surveillance and prescribing data. Br J Gen Pract 2007, in press.
51. World Health Organisation 2001. WHO global strategy for containment of antimicrobial resistance. http://www.who.int/csr/resources/ publications/drugresist/WHO_CDS_CSR_DRS_2001_2_EN/en/ (23 February 2007, date last accessed).
52. World Health Organisation. World Health Report on Infectious Diseases 2000. Overcoming Antimicrobial Resistance. http://www.who. int/infectious-disease-report/2000/other_versions/index-rpt2000_text.html (23 February 2007, date last accessed).
53. Norrby SR, Nord CE, Finch R. Lack of development of new antimicrobial drugs: a potential serious threat to public health. Lancet Infect Dis 2005; 5: 115-9.
54. Finch R. Gram-positive infections: lessons learnt and novel solutions. Clin Microbiol Infect 2006; 12 Suppl 8: 3-8.
55. Report of the Select Committee on Science and Technology of the House of Lords 1998. Resistance to Antibiotics and Other Antimicrobial Agents (chapter 5). http://www.parliament.the-stationeryoffice. co.uk/pa/ld199798/ldselect/ldsctech/081vii/st0701.htm.
56. Lewis D. Antimicrobial resistance surveillance: methods will depend on objectives. J Antimicrob Chemother 2002; 49: 3-5.