Clinical relevance of laboratory-reported antibiotic resistance in acute uncomplicated urinary tract infection in primary care

Journal of Antimicrobial Chemotherapy

Volumn 58, Issue 5, 2006, Pages 1000-1008

  McNulty, C A M ^a   Richards, J ^b   Livermore, D M ^c   Little, P ^d   Charlett, A ^c   Freeman, E ^e   Harvey, I ^f   Thomas, M ^g,h  

^a GLOUCESTERSHIRE ROYAL HOSPITAL   (United Kingdom)

^b NORFOLK AND NORWICH UNIVERSITY HOSPITAL   (United Kingdom)

^c PUBLIC HEALTH ENGLAND   (United Kingdom)

^d UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^e Gloucestershire Research and Development Support Unit   (United Kingdom)

^f UNIVERSITY OF EAST ANGLIA   (United Kingdom)

^g UNIVERSITY OF ABERDEEN   (United Kingdom)

^h Minchinhampton Surgery   (United Kingdom)

Author keywords

Clinical outcome; Cohort; Community primary care; Trimethoprim; UTI

Indexed keywords

ANTIINFECTIVE AGENT; TRIMETHOPRIM;

ACUTE DISEASE; ADULT; AGED; ANTIBIOTIC RESISTANCE; ARTICLE; COHORT ANALYSIS; COMMUNICABLE DISEASE; FEMALE; HUMAN; MICROBIOLOGICAL EXAMINATION; MICROBIOLOGY; MIDDLE AGED; PRIMARY HEALTH CARE; PROSPECTIVE STUDY; TREATMENT OUTCOME; URINARY TRACT INFECTION;

ACUTE DISEASE; ADULT; AGED; ANTI-INFECTIVE AGENTS; COHORT STUDIES; COMMUNITY-ACQUIRED INFECTIONS; FEMALE; HUMANS; MICROBIAL SENSITIVITY TESTS; MIDDLE AGED; PRIMARY HEALTH CARE; PROSPECTIVE STUDIES; TREATMENT OUTCOME; TRIMETHOPRIM; TRIMETHOPRIM RESISTANCE; URINARY TRACT INFECTIONS;

EID: 34248212696     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkl368     Document Type: Article

References (33)

1. Fry J. Medicine in Three Societies. Lancaster: Medical and Technical Publishing Co. Ltd, 1969.
2. Royal College of General Practitioners Office of Population Consensus & Survey. Department of Health Morbidity Statistics from General Practice, 1991-1992. London: HMSO, 1995.
3. Car J. Urinary tract infections in women: Diagnosis and management in primary care. BMJ 2006; 332: 94-7.
4. Hummers-Pradier E, Kocken MM. Urinary tract infections in adult general practice patients. Br J Gen Pract 2002; 52: 752-61.
5. Gupta K, Hooton TM, Stamm WE. Increasing antimicrobial resistance and the management of uncomplicated community-acquired urinary tract infections. Ann Intern Med 2001; 135: 41-50.
6. McNulty CAM, Bowen J, Clark G et al. How should general practitioners investigate suspected urinary tract infection? Variations in laboratory-confirmed bacteriuria in South West England. Commun Dis Public Health 2004; 7: 220-6.
7. Gossius G, Vorland L. The treatment of acute dysuria-frequency syndrome in adult women: Double blind randomised comparison of three day versus ten day trimethoprim therapy. Curr Ther Res Clin Exp 1985; 37 34-42.
8. Tan TY, McNulty C, Charlett A et al. Laboratory antibiotic susceptibility reporting and antibiotic prescribing in general practice. J Antimicrob Chemother 2003; 51: 379-84.
9. PRODIGY Guidance. Urinary Tract Infection (lower) - Women. http://www.prodigy.nhs.uk/guidance.asp?gt=Urinary%20tract%20infection %20(lower)%20-%20women (1 June 2006, date last accessed).
10. Donnan PT, Wei L, Steinke DT et al. Presence of bacteriuria caused by trimethoprim resistant bacteria in patients prescribed antibiotics: multilevel model with practice and individual patient data. BMJ 2004; 328: 1297.
11. Magee JT, Pritchard EL, Fitsgerald KA et al. Antibiotic prescribing and antibiotic resistance in community practice: retrospective study 1996-98. BMJ 1999; 319: 1239-40.
12. Spencer RC, Moseley DJ, Greensmith MJ. Nitrofurantoin modified release versus trimethoprim or co-trimoxazole in the treatment of uncomplicated urinary tract infection in general practice. J Antimicrob Chemother 1994; 33 Suppl A: 121-9.
13. Minassian MA, Lewis DA, Chattopadhyay D et al. A comparison between single-dose fosfomycin trometamol (Monuril) and a 5-day course of trimethoprim in the treatment of uncomplicated lower urinary tract infection in women. Int J Antimicrob Agents 1998; 10: 39-47.
14. Hiscoke C, Yoxall H, Greig D et al. Validation of a method for the rapid diagnosis of urinary tract infection suitable for use in general practice. Br J Gen Pract 1990; 40: 403-5.
15. European Confederation of Laboratory Medicine. European Urinalysis Guidelines. In: Kouri T, Fogazzi G, Gant V et al, eds. Scand J Clin Lab Invest 2000; 60 Suppl 231: S1-96.
16. PHLS Standard Operating Procedure: Investigation of urine. Ref. No. BSOP41 Issue No. 1 02.04.1998. Technical Services, PHLS HQ, London. HPA Issue No. 5 28.02.05. http://www.hpa-standardmethods.org.uk/documents/ bsop/pdf/bsop41.pdf (1 June 2006, date last accessed).
17. Andrews JM. Determination of minimum inhibitory concentrations. BSAC guide to antimicrobial susceptibility testing. J Antimicrob Chemother 2001; 48 Suppl 1: 5-16.
18. Watson L, Little P, Williamson I et al. Validation study of a diary for use in acute lower respiratory tract infection. Fam Pract 2001; 18: 553-4.
19. Little PS. Development and Randomised Controlled Trial of Dipsticks and Diagnostic Algorithms for the Management of UTI. NHS Research & Development Health Technology Assessment Programme 2003. International Standard Randomised Controlled Trial Number 03525333. http://www.controlled-trials.com/isrctn/trial/%7C/0/03525333.html (1 June 2006, date last accessed).
20. Little P, Williamson I, Warner G et al. Open randomised trial of prescribing strategies for sore throat. Br Med J 1997; 314: 722-7.
21. Cox DR. Regression models and life tables (with discussion). J R Stat Soc [Ser B] 1972; 34: 187-200.
22. Bent S, Nallamouthu BK, Simel DL et al. Does this woman have an acute uncomplicated urinary tract infection. JAMA 2002; 287: 2701-10.
23. Richards D, Toop L, Chambers S et al. Response to antibiotics of women with symptoms of urinary tract infection but negative dipstick urine test results: Double blind randomised controlled trial. BMJ 2005; 331: 143-6.
24. Livermore DM. Minimising antibiotic resistance. Lancet Infect Dis 2005; 5: 450-9.
25. Calbo E, Romani V, Xercavins M et al. Risk factors for community-onset urinary tract infections due to Escherchia coli harbouring extended-spectrum β-lactamases. J Antimicrob Chemother 2006; 57: 780-3.
26. Livermore D, Woodford N. Laboratory detection of bacteria with extended-spectrum beta-lactamases. CDR Weekly 2004; 14: 27.
27. Lewis D, McNulty CAM, Lovering A et al. Antimicrobial resistance surveillance in primary care: Practicalities of different methods. In: Health Protection Agency Inaugural Conference, University of Warwick 2003, Abstract P109, p208-9. Health Protection Agency, London.
28. Christiaens TCM, Meyere M De, Vershcraegen G et al. Randomised controlled trial of nitrofurantoin versus placebo in the treatment of uncomplicated urinary tract infection in adult women. Br J Gen Pract 2002; 52: 729-34.
29. Masterton RG, Bochsler JA. High-dosage co-amoxiclav in a single dose versus 7 days of co-trimoxazole as treatment of uncomplicated lower urinary tract infection in women. J Antimicrob Chemother 1995; 35: 129-73.
30. McCarty JA, Richard G, Huck W et al. A randomised trial of shortcourse ciprofloxacin, ofloxacin, or trimethoprim/suflamethoxazole for the treatment of acute urinary tract infection in women. Am J Med 1999; 106: 292-9.
31. Hay AD, Thomas M, Montgomery A et al. The relationship between primary care antibiotic prescribing and bacterial resistance in adults in the community: A controlled observational study using individual patient data. J Antimicrob Chemother 2005; 56: 146-53.
32. Health Protection Agency. Management of Infection Guidance for Primary Care. http://193.129.245.226/infections/topics_az/ primary_care_guidance/Antibiotic_guide_250506.rtf (1 June 2006, date last accessed).
33. Woodford N, Ward ME, Kaufmann ME et al. Community and hospital spread of Escherichia coli producing CTX-M extended-spectrum beta-lactamases in the UK. J Antimicrob Chemother 2004; 54: 735-43.