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Volumn 68, Issue 3, 2007, Pages 134-142

Synthesis, analgesic, anti-inflammatory and ulcerogenic index activities of novel 2-methylthio-3-substituted-5,6- dimethyl thieno [2,3-d] pyrimidin-4(3H)-ones

Author keywords

Albino mice; Analgesic; Anti inflammatory; Pyrimidine; Thienopyrimidine; Thioureas; Wistar rats

Indexed keywords

2 (1 ETHYLPROPYLIDENEAMINO) 2 METHYLTHIO 5,6 DIMETHYLTHIENO[2,3 D]PYRIMIDIN 4(3H) ONE; 2 (1 METHYLBUTYLIDENEAMINO) 2 METHYLTHIO 5,6 DIMETHYLTHIENO[2,3 D]PYRIMIDIN 4(3H) ONE; 2 (1 METHYLPROPYLIDENEAMINO) 2 METHYLTHIO 5,6 DIMETHYLTHIENO[2,3 D]PYRIMIDIN 4(3H) ONE; 2 AMINO 3 CARBETHOXY 4,5 DIMETHYLTHIOPHENE; 3 AMINO 2 METHYLTHIO 5,6 DIMETHYLTHIENO[2,3 D]PYRIMIDIN 4(3H) ONE; ACETYLSALICYLIC ACID; ALDEHYDE; DICLOFENAC; KETONE; QUINAZOLINE DERIVATIVE; UNCLASSIFIED DRUG;

EID: 34848910215     PISSN: 02724391     EISSN: 10982299     Source Type: Journal    
DOI: 10.1002/ddr.20171     Document Type: Article
Times cited : (9)

References (17)
  • 1
    • 0038746787 scopus 로고    scopus 로고
    • Synthesis and antimicrobial testing of some new S-substituted-thiopyridines, thienopyridines, pyridothienopyrimidines and pyridothienotriazines
    • Abdel-Rahman AE, Bakhite EA, Al-Taifi EA. 2003. Synthesis and antimicrobial testing of some new S-substituted-thiopyridines, thienopyridines, pyridothienopyrimidines and pyridothienotriazines. Pharmazie 58:372-377.
    • (2003) Pharmazie , vol.58 , pp. 372-377
    • Abdel-Rahman, A.E.1    Bakhite, E.A.2    Al-Taifi, E.A.3
  • 3
    • 0242500881 scopus 로고    scopus 로고
    • Synthesis and pharmacological investigation of some novel 2,3-disubstituted quinazolin-4(3H)-ones as analgesic and antiinflammatory agents
    • Alagarsamy V, Revathi R, Vijayakumar S, Ramseshu KV. 2003a. Synthesis and pharmacological investigation of some novel 2,3-disubstituted quinazolin-4(3H)-ones as analgesic and antiinflammatory agents. Pharmazie 58:233-236.
    • (2003) Pharmazie , vol.58 , pp. 233-236
    • Alagarsamy, V.1    Revathi, R.2    Vijayakumar, S.3    Ramseshu, K.V.4
  • 4
    • 10844248503 scopus 로고    scopus 로고
    • Synthesis, analgesic, anti-inflammatory and antibacterial activities of some novel 2-methyl-3-substituted quinazolin-4-(3H)-ones
    • Alagarsamy V, Murugananthan G, Venkateshperumal R. 2003b. Synthesis, analgesic, anti-inflammatory and antibacterial activities of some novel 2-methyl-3-substituted quinazolin-4-(3H)-ones. Biol Pharm Bull 26:1711-1714.
    • (2003) Biol Pharm Bull , vol.26 , pp. 1711-1714
    • Alagarsamy, V.1    Murugananthan, G.2    Venkateshperumal, R.3
  • 5
    • 0642378328 scopus 로고    scopus 로고
    • Synthesis, analgesic and anti-inflammatory activities of some novel 2,3-disubstituted quinazolin-4(3H)-ones
    • Alagarsamy V, Muthukumar V, Pavalarani N, Vasanthanathan P, Revathi R. 2003c. Synthesis, analgesic and anti-inflammatory activities of some novel 2,3-disubstituted quinazolin-4(3H)-ones. Biol Pharm Bull 26:557-559.
    • (2003) Biol Pharm Bull , vol.26 , pp. 557-559
    • Alagarsamy, V.1    Muthukumar, V.2    Pavalarani, N.3    Vasanthanathan, P.4    Revathi, R.5
  • 6
    • 16644386905 scopus 로고    scopus 로고
    • Synthesis, analgesic, anti-inflammatory and antibacterial activities of some novel 2-methylthio-3-substituted quinazolin-4(3H)-ones
    • Alagarsamy V, Rajesh R, Meena R, Vijaykumar S, Ramseshu KV, Duraianandakumar T. 2004. Synthesis, analgesic, anti-inflammatory and antibacterial activities of some novel 2-methylthio-3-substituted quinazolin-4(3H)-ones. Biol Pharm Bull 27: 652-656.
    • (2004) Biol Pharm Bull , vol.27 , pp. 652-656
    • Alagarsamy, V.1    Rajesh, R.2    Meena, R.3    Vijaykumar, S.4    Ramseshu, K.V.5    Duraianandakumar, T.6
  • 8
    • 0002261078 scopus 로고
    • A method for determinating loss of pain sensation
    • Amour RE, Smith DL. 1941. A method for determinating loss of pain sensation. J Pharm Exp Ther 72:74-78.
    • (1941) J Pharm Exp Ther , vol.72 , pp. 74-78
    • Amour, R.E.1    Smith, D.L.2
  • 9
    • 0037366454 scopus 로고    scopus 로고
    • Synthesis and preliminary evaluation of some N-[5-(2-furanyl)-2-methyl-4-oxo-4H-thieno[2,3-d] pyrimidin-3-yl]-carboxamide and 3-substituted-5-(2-furanyl)-2-methyl-3H- thieno[2,3-d]pyrimidin-4-ones as antimicrobial agents
    • Chambhare RV, Khadse BG, Bobde AS, Bahekar RH. 2003. Synthesis and preliminary evaluation of some N-[5-(2-furanyl)-2-methyl-4-oxo-4H-thieno[2,3-d] pyrimidin-3-yl]-carboxamide and 3-substituted-5-(2-furanyl)-2-methyl-3H- thieno[2,3-d]pyrimidin-4-ones as antimicrobial agents. Eur J Med Chem 38: 89-100.
    • (2003) Eur J Med Chem , vol.38 , pp. 89-100
    • Chambhare, R.V.1    Khadse, B.G.2    Bobde, A.S.3    Bahekar, R.H.4
  • 10
    • 0015908751 scopus 로고
    • Effect of bilateral adrenalectomy on production of restraint ulcers in the stomach of albino rats
    • Ganguly AK, Bhatnagar OP. 1973. Effect of bilateral adrenalectomy on production of restraint ulcers in the stomach of albino rats. Can J Phys Pharmacol 51:748-750.
    • (1973) Can J Phys Pharmacol , vol.51 , pp. 748-750
    • Ganguly, A.K.1    Bhatnagar, O.P.2
  • 11
    • 84860875380 scopus 로고
    • 2-Amino thiophene aus methylenaktiven Nitrilen, Carbonylverbindungen und Schwefel
    • Gewald K, Schinke E, Bottcher H. 1966. 2-Amino thiophene aus methylenaktiven Nitrilen, Carbonylverbindungen und Schwefel. Chem Ber 99:94-100.
    • (1966) Chem Ber , vol.99 , pp. 94-100
    • Gewald, K.1    Schinke, E.2    Bottcher, H.3
  • 12
    • 0021909910 scopus 로고
    • The effect of biological variables on the anti-ulcerogenic effect of vegetable plantain banana
    • Goyal RK, Chakrabarti A, Sanyal AK. 1985. The effect of biological variables on the anti-ulcerogenic effect of vegetable plantain banana. Plant Med 29:85-88.
    • (1985) Plant Med , vol.29 , pp. 85-88
    • Goyal, R.K.1    Chakrabarti, A.2    Sanyal, A.K.3
  • 13
    • 0019195797 scopus 로고
    • Heat and other physiological stress-induced analgesia: Catecholamine mediated and naloxone reversible response
    • Kulkarni SK. 1980. Heat and other physiological stress-induced analgesia: catecholamine mediated and naloxone reversible response. Life Sci 27:185-188.
    • (1980) Life Sci , vol.27 , pp. 185-188
    • Kulkarni, S.K.1
  • 14
    • 11844255399 scopus 로고    scopus 로고
    • Bioisosterism: A useful strategy for molecular modification and drug design
    • Lima LM, Barreiro EJ. 2005. Bioisosterism: a useful strategy for molecular modification and drug design. Curr Med Chem 12:23-38.
    • (2005) Curr Med Chem , vol.12 , pp. 23-38
    • Lima, L.M.1    Barreiro, E.J.2
  • 15
    • 0029561836 scopus 로고
    • Synthesis and pharmacological evaluation of thieno[2,3-d]pyrimidin-2,4-dione and 5H-pyrimido [5,4-b]indol-2,4-dione derivatives
    • Santagati NA, Caruso A, Cutuli VMC, Caccamo F. 1995. Synthesis and pharmacological evaluation of thieno[2,3-d]pyrimidin-2,4-dione and 5H-pyrimido [5,4-b]indol-2,4-dione derivatives. Il Farmaco 50:689-695.
    • (1995) Il Farmaco , vol.50 , pp. 689-695
    • Santagati, N.A.1    Caruso, A.2    Cutuli, V.M.C.3    Caccamo, F.4
  • 17
    • 67249094291 scopus 로고
    • Carregeenin induced oedema in hind paw of the rat as assay for antiinflammatory drugs
    • Winter CA, Risely EA, Nuss GW. 1962. Carregeenin induced oedema in hind paw of the rat as assay for antiinflammatory drugs. Exp Biol Med 111:544-547.
    • (1962) Exp Biol Med , vol.111 , pp. 544-547
    • Winter, C.A.1    Risely, E.A.2    Nuss, G.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.