Synthesis and pharmacological investigation of some novel 2,3-disubstituted quinazolin-4(3H)-ones as analgesic and antiinflammatory agents

Pharmazie

Volumn 58, Issue 4, 2003, Pages 233-236

  Alagarsamy, V ^a   Meena, S ^b   Vijayakumar, S ^b   Ramseshu, K V ^b   Revathi, R ^a  

^a SB College of Pharmacy   (India)

^b K M COLLEGE OF PHARMACY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

2 MERCAPTO 3 (1 PHENYL 3 PROPYLIDENE)QUINAZOLIN 4(3H) ONE; 2 METHYLTHIO 3 (2 BUTYLIDENE)QUINAZOLIN 4(3H) ONE; 2 PHENYL 3 (2 BUTYLIDENE)QUINAZOLIN 4(3H) ONE; 2 PHENYL 3,1 BENZOXAZIN 4 ONE; 3 AMINO 2 MERCAPTOQUINAZOLIN 4(3H) ONE; 3 AMINO 2 METHYLTHIOQUINAZOLIN 4(3H) ONE; 3 AMINO 2 PHENYLQUINAZOLIN 4(3H) ONE; ALDEHYDE; ANALGESIC AGENT; ANTIINFLAMMATORY AGENT; DICLOFENAC; KETONE; QUINAZOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG POTENCY; DRUG PURITY; DRUG STRUCTURE; DRUG SYNTHESIS; INFRARED SPECTROSCOPY; MASS SPECTROMETRY; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SPECTROSCOPY; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CARRAGEENAN; EDEMA; INDICATORS AND REAGENTS; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; QUINAZOLINES; RATS; SPECTROPHOTOMETRY, INFRARED;

EID: 0242500881     PISSN: 00317144     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. Saravanan, K.; Mohan, S.; Manjunatha, K. S.: Ind. J. Heterocycl. Chem. 8, 55 (1998)
2. Chao, P.; Deng, QL, H.; Lynn, C.; Shih, G., Hsienchengi Leoni, S.; Lorenzom, V.; Genini, V.; Davide, K.; Carson, Y.; Dennis, A.; Lottarn, R.; Howard, B.: J. Med. Chem. 42, 3860 (1999)
3. Ibrahim, M. K.: Egypt. J. Pharm. Sci. 39, 519 (1999)
4. Kovalenko, S. I.: Farm. Zh. (Kiev) 1, 64 (1999)
5. Pandey, V. K.; Raj, N.: Curr. Sci. 55, 785 (1985)
6. Desai, N. C.; Bhatt, J. J.; Undavia, N. K.: Farmaco 51, 361 (1996)
7. Alagarsamy, V.; Prabakaran, L.; Duraimurugan, R.; Gurumurthy, G.; Bindu, P.; Arun kumar, M.; Bothiraja, C.: Acta. Pharm. Turc. 42, 33 (2000)
8. Anil, K.; Saxna, M.; Arzenim. Forsch. 39, 35 (1992)
9. Garcia, J. D.; Somanathan, R.; Rivero, I. A.; Aguirre, G.; Hellberg, L. H.: Synth. Commun. 30, 2707 (2000)
10. Rivero, I. A.; Somanathan, R.; Hellberg, L. H.: Synth. Commun. 28, 2077 (1998)
11. Lipunova, G. N.; Mokrushina, E. V.; Sidorova, L. P.; Charushin, V. N.: Pharm. Chem. J. 34, 19 (2000)
12. Manabu, H.; Ryvichi, I.; Hideaki, H.: Chem. Pharm. Bull. 38, 618 (1990)
13. Pandeya, S. N.; Sriram, D.; Alagarsamy, V.: Acta. Pharm. Turc. 41, 391 (1999)
14. Alagarsamy, V.; Pathak, U. S.; Goyal, R. K.: Ind. J. Pharm. Sci. 62, 63 (2000)
15. Kulkarni, S. K.: Life Sci. 27, 185 (1980)
16. Amour R. E.; and Smith, D. L.: J. Pharm. Expt. Therap. 72, 74 (1941)
17. Winter, C. A.; Risely, E. A.; Nu, G. N.: Proc. Soc. Exp. Biol. 111, 54719 (1982)