Nitroimidazoles. V. Synthesis and anti-HIV evaluation of new 5-substituted piperazinyl-4-nitroimidazole derivatives

Acta Pharmaceutica

Volumn 57, Issue 4, 2007, Pages 379-393

  Al Soud, Yaseen A ^a   Al Masoudi, Najim A ^b   Hassan, Hamed Gh ^c   De Clercq, Erik ^d   Pannecouque, Christophe ^d  

^a AL AL BAYT UNIVERSITY   (Jordan)

^b UNIVERSITY OF KONSTANZ   (Germany)

^c UNIVERSITY OF SULAIMANI   (Iraq)

^d REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

4 nitroimidazoles; Anti HIV activity; NNRTIs; Piperazine

Indexed keywords

1 [4 (1 BENZYL 2 ETHYL 4 NITRO 1H IMIDAZOL 5 YL) PIPERAZIN 1 YL] 2 (4 CHLOROBENZYLTHIO)ETHANONE; 1 [4 (1 BENZYL 2 ETHYL 4 NITRO 1H IMIDAZOL 5 YL) PIPERAZIN 1 YL] 2 (4 CHLOROPHENYLTHIO)ETHANONE; 1 [4 (1 BENZYL 2 ETHYL 4 NITRO 1H IMIDAZOL 5 YL) PIPERAZIN 1 YL] 2 (4 METHOXYPHENYLTHIO)ETHANONE; 1 [4 (1 BENZYL 2 ETHYL 4 NITRO 1H IMIDAZOL 5 YL) PIPERAZIN 1 YL] 2 (BENZYLTHIO)ETHANONE; 1 [4 (1 BENZYL 2 ETHYL 4 NITRO 1H IMIDAZOL 5 YL) PIPERAZIN 1 YL] 2 (NAPHTHALENE 1 YL SULPHONYL)ETHANONE; 1 [4 (1 BENZYL 2 ETHYL 4 NITRO 1H IMIDAZOL 5 YL) PIPERAZIN 1 YL] 2 (NAPTHALENTHIO)ETHANONE; 1 [4 (1 BENZYL 2 ETHYL 4 NITRO 1H IMIDAZOL 5 YL) PIPERAZIN 1 YL] 2 (PHENYLTHIO)ETHANONE; 1 [4 (1 BENZYL 2 ETHYL 4 NITRO 1H IMIDAZOL 5 YL) PIPERAZIN 1 YL] 2 CHLOROMETHYLENE KETONE; 3 (1H INDOL 3 YL) 1 [4 (1 BENZYL 2 ETHYL 4 NITRO 1H IMIDAZOL 5 YL) PIPERAZIN 1 YL]PROPAN 1 ONE; 4 NITROIMIDAZOLE DERIVATIVE; 4 [4 (1 BENZYL 2 ETHYL 4 NITRO 1H IMIDAZOL 5 YL) PIPERAZIN 1 YL] 4 OXO BUTANAMIDE; ETHYL 2 [2 (4 (1 BENZYL 2 ETHYL 4 NITRO 1H IMIDAZOL 5 YL)PIPERAZIN 1 YL) 2 OXOETHYLTHIO]ACETATE; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY; IMIDAZOLE DERIVATIVE; INDOLE DERIVATIVE; KETONE DERIVATIVE; METHYL 4 [4 (1 BENZYL 2 ETHYL 4 NITRO 1H IMIDAZOL 5 YL) PIPERAZIN 1 YL] 4 OXO BUTANOATE; NITROIMIDAZOLE DERIVATIVE; RNA DIRECTED DNA POLYMERASE INHIBITOR; UNCLASSIFIED DRUG; [4 (1 BENZYL 2 ETHYL 4 NITRO 1H IMIDAZOL 5 YL) PIPERAZIN 1 YL](2,4 DICHLOROPHENYL)KETONE; [4 (1 BENZYL 2 ETHYL 4 NITRO 1H IMIDAZOL 5 YL) PIPERAZIN 1 YL](4 CHLOROPHENYL)KETONE; [4 (1 BENZYL 2 ETHYL 4 NITRO 1H IMIDAZOL 5 YL) PIPERAZIN 1 YL](4 FLUOROPHENYL)KETONE; [4 (1 BENZYL 2 ETHYL 4 NITRO 1H IMIDAZOL 5 YL) PIPERAZIN 1 YL](4 METHOXYPHENYL)KETONE; [4 (1 BENZYL 2 ETHYL 4 NITRO 1H IMIDAZOL 5 YL) PIPERAZIN 1 YL](4 NITROPHENYL)KETONE; [4 (1 BENZYL 2 ETHYL 4 NITRO 1H IMIDAZOL 5 YL) PIPERAZIN 1 YL](9H CARBAZOL 9 YL)METHYLCARBOXYLATE; [4 (1 BENZYL 2 ETHYL 4 NITRO 1H IMIDAZOL 5 YL) PIPERAZIN 1 YL](THIOPHEN 2 YL)KETONE; [4 (1 BENZYL 2 ETHYL 4 NITRO 1H IMIDAZOL 5 YL) PIPERAZIN 1 YL]METHYL KETONE;

ANTIVIRAL ACTIVITY; ARTICLE; DOSE RESPONSE; DRUG INHIBITION; DRUG SYNTHESIS; EVALUATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2;

EID: 34848870695     PISSN: 13300075     EISSN: None     Source Type: Journal    
DOI: 10.2478/v10007-007-0031-7     Document Type: Article

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