Production of a recombinant antibody fragment in whole insect larvae

Molecular Biotechnology

Volumn 36, Issue 1, 2007, Pages 44-51

  O'Connell, Kevin P ^a   Kovaleva, Elena ^b   Campbell, James H ^b   Anderson, Patricia E ^a   Brown, Susan G ^b   Davis, David C ^b   Valdes, James J ^a   Welch, Richard W ^b   Bentley, William E ^c   Van Beek, Nikolai A ^b  

^a EDGEWOOD CHEMICAL BIOLOGICAL CENTER   (United States)

^b Chesapeake PERL Inc   (United States)

^c UNIVERSITY OF MARYLAND   (United States)

Author keywords

Anti botulinum Fab; Baculovirus; Insect larvae; Large scale production

Indexed keywords

CELL CULTURE; CELLS; DRUG PRODUCTS; HORMONES; VIRUSES;

ANTI BOTULINUM FAB; BACULOVIRUS; INSECT LARVAE; LARGE SCALE PRODUCTION;

ANTIBODIES;

BOMBYXIN; BOTULINUM TOXIN A; IMMUNOGLOBULIN F(AB) FRAGMENT; RECOMBINANT ANTIBODY; ANTIBODY; BOTULINUM TOXIN; RECOMBINANT PROTEIN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTHROPOD LARVA; ARTICLE; BACULOVIRUS EXPRESSION SYSTEM; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; INFECTION; NONHUMAN; PROTEIN PURIFICATION; PROTEIN SECRETION; SILKWORM; WESTERN BLOTTING; ANIMAL; BACULOVIRUS; BIOSYNTHESIS; GEL CHROMATOGRAPHY; GENETICS; GROWTH, DEVELOPMENT AND AGING; IMMUNOLOGY; INSECT; ISOLATION AND PURIFICATION; LARVA; METABOLISM; MOLECULAR CLONING; MOUSE; POLYACRYLAMIDE GEL ELECTROPHORESIS; VIROLOGY;

BOMBYX MORI; HEXAPODA; MAMMALIA; TRICHOPLUSIA NI;

ANIMALS; ANTIBODIES; BACULOVIRIDAE; BOTULINUM TOXINS; CHROMATOGRAPHY, GEL; CLONING, MOLECULAR; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME-LINKED IMMUNOSORBENT ASSAY; IMMUNOGLOBULIN FAB FRAGMENTS; INSECTS; LARVA; MICE; RECOMBINANT PROTEINS;

EID: 34848863681     PISSN: 10736085     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12033-007-0014-4     Document Type: Article

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