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Volumn 23, Issue 6, 2007, Pages 667-672

Hygiene, microbial diversity and immune regulation

Author keywords

Allergy; Asthma; IBD; Microbiota; Regulatory T cells

Indexed keywords

CYTOKINE;

EID: 34848856098     PISSN: 02671379     EISSN: None     Source Type: Journal    
DOI: 10.1097/MOG.0b013e3282eeb43b     Document Type: Review
Times cited : (26)

References (59)
  • 1
    • 33846535227 scopus 로고    scopus 로고
    • I've got a little list
    • Koplan JP. I've got a little list. BMJ 2007; 334 (Suppl 1):s20.
    • (2007) BMJ , vol.334 , Issue.SUPPL. 1
    • Koplan, J.P.1
  • 2
    • 34447641265 scopus 로고    scopus 로고
    • Mackenbach JP. Sanitation: pragmatism works. BMJ 2007; 334 (Suppl 1):s17. The authors provide interesting comments on the origin of the first regulatory measures to provide sanitation in cities from England and Wales.
    • Mackenbach JP. Sanitation: pragmatism works. BMJ 2007; 334 (Suppl 1):s17. The authors provide interesting comments on the origin of the first regulatory measures to provide sanitation in cities from England and Wales.
  • 3
    • 34447643249 scopus 로고    scopus 로고
    • Germ theory: Invisible killers revealed
    • Burns H. Germ theory: invisible killers revealed. BMJ 2007; 334 (Suppl 1):s11.
    • (2007) BMJ , vol.334 , Issue.SUPPL. 1
    • Burns, H.1
  • 4
    • 0036330319 scopus 로고    scopus 로고
    • Give us this day our daily germs
    • Rook GA, Brunet LR. Give us this day our daily germs. Biologist (London) 2002; 49:145-149.
    • (2002) Biologist (London) , vol.49 , pp. 145-149
    • Rook, G.A.1    Brunet, L.R.2
  • 5
    • 33646413182 scopus 로고    scopus 로고
    • Mechanisms of disease: The hygiene hypothesis revisited
    • The gut is a principal scenario for immune regulation in the intestinal mucosa and beyond
    • Guarner F, Bourdet-Sicard R, Brandtzaeg P, et al. Mechanisms of disease: the hygiene hypothesis revisited. Nat Clin Pract Gastroenterol Hepatol 2006; 3:275-284. The gut is a principal scenario for immune regulation in the intestinal mucosa and beyond.
    • (2006) Nat Clin Pract Gastroenterol Hepatol , vol.3 , pp. 275-284
    • Guarner, F.1    Bourdet-Sicard, R.2    Brandtzaeg, P.3
  • 6
    • 34248585191 scopus 로고    scopus 로고
    • Inverse association between rural environment in infancy and sensitization to rodents in adulthood
    • Dorevitch S, Tharenos L, Demirtas H, et al. Inverse association between rural environment in infancy and sensitization to rodents in adulthood. Ann Allergy Asthma Immunol 2007; 98:440-446.
    • (2007) Ann Allergy Asthma Immunol , vol.98 , pp. 440-446
    • Dorevitch, S.1    Tharenos, L.2    Demirtas, H.3
  • 7
    • 33750067035 scopus 로고    scopus 로고
    • Prevalence of asthma and allergic diseases in Sanliurfa, Turkey, and the relation to environmental and socioeconomic factors: Is the hygiene hypothesis enough?
    • Zeyrek CD, Zeyrek F, Sevinc E, Demir E. Prevalence of asthma and allergic diseases in Sanliurfa, Turkey, and the relation to environmental and socioeconomic factors: is the hygiene hypothesis enough? J Investig Allergol Clin Immunol 2006; 16:290-295.
    • (2006) J Investig Allergol Clin Immunol , vol.16 , pp. 290-295
    • Zeyrek, C.D.1    Zeyrek, F.2    Sevinc, E.3    Demir, E.4
  • 8
    • 33847654642 scopus 로고    scopus 로고
    • The EPIVIR study group. Allergic sensitization and microbial load - a comparison between Finland and Russian Karelia
    • Seiskari T, Kondrashova A, Viskari H, et al., The EPIVIR study group. Allergic sensitization and microbial load - a comparison between Finland and Russian Karelia. Clin Exp Immunol 2007; 148:47-52.
    • (2007) Clin Exp Immunol , vol.148 , pp. 47-52
    • Seiskari, T.1    Kondrashova, A.2    Viskari, H.3
  • 9
    • 30844433756 scopus 로고    scopus 로고
    • Kinra S, Davey Smith G, Jeffreys M, et al. Association between sibship size and allergic diseases in the Glasgow Alumni Study. Thorax 2006; 61:48-53. This splendid investigation was based on alumni surveys performed 40-60 years ago.
    • Kinra S, Davey Smith G, Jeffreys M, et al. Association between sibship size and allergic diseases in the Glasgow Alumni Study. Thorax 2006; 61:48-53. This splendid investigation was based on alumni surveys performed 40-60 years ago.
  • 10
    • 34250805993 scopus 로고    scopus 로고
    • Asthma prevalence, family size and birth order
    • Goldberg S, Israeli E, Schwartz S, et al. Asthma prevalence, family size and birth order. Chest 2007; 131:1747-1752.
    • (2007) Chest , vol.131 , pp. 1747-1752
    • Goldberg, S.1    Israeli, E.2    Schwartz, S.3
  • 12
    • 12544258106 scopus 로고    scopus 로고
    • Exposure to infant siblings during early life and risk of multiple sclerosis
    • Ponsonby AL, van der Mei I, Dwyer T, et al. Exposure to infant siblings during early life and risk of multiple sclerosis. JAMA 2005; 293:463-469.
    • (2005) JAMA , vol.293 , pp. 463-469
    • Ponsonby, A.L.1    van der Mei, I.2    Dwyer, T.3
  • 13
    • 24944573572 scopus 로고    scopus 로고
    • Canadian Collaborative Study Group. Multiple sclerosis and birth order: A longitudinal cohort study
    • Sadovnick AD, Yee IM, Ebers GC, Canadian Collaborative Study Group. Multiple sclerosis and birth order: a longitudinal cohort study. Lancet Neurol 2005; 4:611-617.
    • (2005) Lancet Neurol , vol.4 , pp. 611-617
    • Sadovnick, A.D.1    Yee, I.M.2    Ebers, G.C.3
  • 14
    • 33846904375 scopus 로고    scopus 로고
    • House cleaning with chlorine bleach and the risks of allergic and respiratory diseases in children
    • Nickmilder M, Carbonnelle S, Bernard A. House cleaning with chlorine bleach and the risks of allergic and respiratory diseases in children. Pediatr Allergy Immunol 2007; 18:27-35.
    • (2007) Pediatr Allergy Immunol , vol.18 , pp. 27-35
    • Nickmilder, M.1    Carbonnelle, S.2    Bernard, A.3
  • 15
    • 33646145305 scopus 로고    scopus 로고
    • Endotoxin in inner-city homes: Associations with wheeze and eczema in early childhood
    • Perzanowski MS, Miller RL, Thorne PS, et al. Endotoxin in inner-city homes: associations with wheeze and eczema in early childhood. J Allergy Clin Immunol 2006; 117:1082-1089.
    • (2006) J Allergy Clin Immunol , vol.117 , pp. 1082-1089
    • Perzanowski, M.S.1    Miller, R.L.2    Thorne, P.S.3
  • 16
    • 28444494764 scopus 로고    scopus 로고
    • Bach JF. Infections and autoimmune diseases. J Autoimmun 2005; 25 (Suppl):74-80. This is a very interesting discussion on the dual role of infections in preventing and precipitating autoimmunity.
    • Bach JF. Infections and autoimmune diseases. J Autoimmun 2005; 25 (Suppl):74-80. This is a very interesting discussion on the dual role of infections in preventing and precipitating autoimmunity.
  • 17
    • 33846430019 scopus 로고    scopus 로고
    • Clinical sepsis in neonates is responsible for the lower prevalence of developing allergy
    • Ryozawa M, Matsubara T, Ichiyama T, et al. Clinical sepsis in neonates is responsible for the lower prevalence of developing allergy. Pediatr Int 2007; 49:15-18.
    • (2007) Pediatr Int , vol.49 , pp. 15-18
    • Ryozawa, M.1    Matsubara, T.2    Ichiyama, T.3
  • 18
    • 33746962649 scopus 로고    scopus 로고
    • Prenatal and postnatal exposure to respiratory infection and atopic diseases development: A historical cohort study
    • Zutavern A, von Klot S, Gehring U, et al. Prenatal and postnatal exposure to respiratory infection and atopic diseases development: a historical cohort study. Respir Res 2006; 7:81.
    • (2006) Respir Res , vol.7 , pp. 81
    • Zutavern, A.1    von Klot, S.2    Gehring, U.3
  • 19
    • 33644817193 scopus 로고    scopus 로고
    • Viral infections, cytokine dysregulation and the origins of childhood asthma and allergic diseases
    • Friedlander SL, Jackson DJ, Gangnon RE, et al. Viral infections, cytokine dysregulation and the origins of childhood asthma and allergic diseases. Pediatr Infect Dis J 2005; 24 (11 Suppl):S170-S176.
    • (2005) Pediatr Infect Dis J , vol.24 , Issue.11 SUPPL.
    • Friedlander, S.L.1    Jackson, D.J.2    Gangnon, R.E.3
  • 20
    • 33644700093 scopus 로고    scopus 로고
    • Day-care attendance and increased risk for respiratory and allergic symptoms in preschool age
    • Hagerhed-Engman L, Bornehag CG, Sundell J, Aberg N. Day-care attendance and increased risk for respiratory and allergic symptoms in preschool age. Allergy 2006; 61:447-453.
    • (2006) Allergy , vol.61 , pp. 447-453
    • Hagerhed-Engman, L.1    Bornehag, C.G.2    Sundell, J.3    Aberg, N.4
  • 21
    • 14844299306 scopus 로고    scopus 로고
    • Atopic dermatitis and the 'hygiene hypothesis': Too clean to be true?
    • Flohr C, Pascoe D, Williams HC. Atopic dermatitis and the 'hygiene hypothesis': too clean to be true? Br J Dermatol 2005; 152:202-216.
    • (2005) Br J Dermatol , vol.152 , pp. 202-216
    • Flohr, C.1    Pascoe, D.2    Williams, H.C.3
  • 22
    • 33749024165 scopus 로고    scopus 로고
    • A population-based ecologic study of inflammatory bowel disease: Searching for etiologic clues
    • Green C, Elliott L, Beaudoin C, Bernstein CN. A population-based ecologic study of inflammatory bowel disease: searching for etiologic clues. Am J Epidemiol 2006; 164:615-623.
    • (2006) Am J Epidemiol , vol.164 , pp. 615-623
    • Green, C.1    Elliott, L.2    Beaudoin, C.3    Bernstein, C.N.4
  • 23
    • 33749341758 scopus 로고    scopus 로고
    • Environmental factors in inflammatory bowel disease: A co-twin control study of a Swedish-Danish twin population
    • Halfvarson J, Jess T, Magnuson A, et al. Environmental factors in inflammatory bowel disease: a co-twin control study of a Swedish-Danish twin population. Inflamm Bowel Dis 2006; 12:925-933.
    • (2006) Inflamm Bowel Dis , vol.12 , pp. 925-933
    • Halfvarson, J.1    Jess, T.2    Magnuson, A.3
  • 24
    • 33646381327 scopus 로고    scopus 로고
    • Acute gastroenteritis is followed by an increased risk of inflammatory bowel disease
    • Garcia Rodriguez LA, Ruigomez A, Panes J. Acute gastroenteritis is followed by an increased risk of inflammatory bowel disease. Gastroenterology 2006; 130:1588-1594.
    • (2006) Gastroenterology , vol.130 , pp. 1588-1594
    • Garcia Rodriguez, L.A.1    Ruigomez, A.2    Panes, J.3
  • 26
    • 20544444045 scopus 로고    scopus 로고
    • Diversity of the human intestinal microbial flora
    • Eckburg PB, Bik EM, Bernstein CN, et al. Diversity of the human intestinal microbial flora. Science 2005; 308:1635-1638.
    • (2005) Science , vol.308 , pp. 1635-1638
    • Eckburg, P.B.1    Bik, E.M.2    Bernstein, C.N.3
  • 27
    • 13944260433 scopus 로고    scopus 로고
    • Childhood asthma hospitalization risk after cesarean delivery in former term and premature infants
    • Debley JS, Smith JM, Redding GJ, Critchlow CW. Childhood asthma hospitalization risk after cesarean delivery in former term and premature infants. Ann Allergy Asthma Immunol 2005; 94:228-233.
    • (2005) Ann Allergy Asthma Immunol , vol.94 , pp. 228-233
    • Debley, J.S.1    Smith, J.M.2    Redding, G.J.3    Critchlow, C.W.4
  • 28
    • 24644489353 scopus 로고    scopus 로고
    • Mode of delivery at birth and development of asthma: A population-based cohort study
    • Juhn YJ, Weaver A, Katusic S, Yunginger J. Mode of delivery at birth and development of asthma: a population-based cohort study. J Allergy Clin Immunol 2005; 116:510-516.
    • (2005) J Allergy Clin Immunol , vol.116 , pp. 510-516
    • Juhn, Y.J.1    Weaver, A.2    Katusic, S.3    Yunginger, J.4
  • 29
    • 1542300136 scopus 로고    scopus 로고
    • Effects of intestinal microflora and the environment on the development of asthma and allergy
    • Bjorksten B. Effects of intestinal microflora and the environment on the development of asthma and allergy. Springer Semin Immunopathol 2004; 25:257-270.
    • (2004) Springer Semin Immunopathol , vol.25 , pp. 257-270
    • Bjorksten, B.1
  • 30
    • 21844449698 scopus 로고    scopus 로고
    • Fecal microbiota in sensitized wheezy and nonsensitized nonwheezy children: A nested case-control study
    • Murray CS, Tannock GW, Simon MA, et al. Fecal microbiota in sensitized wheezy and nonsensitized nonwheezy children: a nested case-control study. Clin Exp Allergy 2005; 35:741-745.
    • (2005) Clin Exp Allergy , vol.35 , pp. 741-745
    • Murray, C.S.1    Tannock, G.W.2    Simon, M.A.3
  • 31
    • 33646553320 scopus 로고    scopus 로고
    • Distinct pattern of commensal gut microbiota in toddlers with eczema
    • Mah KW, Bjorksten B, Lee BW, et al. Distinct pattern of commensal gut microbiota in toddlers with eczema. Int Arch Allergy Immunol 2006; 140:157-163.
    • (2006) Int Arch Allergy Immunol , vol.140 , pp. 157-163
    • Mah, K.W.1    Bjorksten, B.2    Lee, B.W.3
  • 32
    • 34247466932 scopus 로고    scopus 로고
    • Gut microbiota composition and development of atopic manifestations in infancy: The KOALA Birth Cohort Study
    • Penders J, Thijs C, van den Brandt PA, et al. Gut microbiota composition and development of atopic manifestations in infancy: the KOALA Birth Cohort Study. Gut 2007; 56:661-667.
    • (2007) Gut , vol.56 , pp. 661-667
    • Penders, J.1    Thijs, C.2    van den Brandt, P.A.3
  • 33
    • 33845404097 scopus 로고    scopus 로고
    • Molecular fingerprinting of the intestinal microbiota of infants in whom atopic eczema was or was not developing
    • Penders J, Stobberingh EE, Thijs C, et al. Molecular fingerprinting of the intestinal microbiota of infants in whom atopic eczema was or was not developing. Clin Exp Allergy 2006; 36:1602-1608.
    • (2006) Clin Exp Allergy , vol.36 , pp. 1602-1608
    • Penders, J.1    Stobberingh, E.E.2    Thijs, C.3
  • 34
    • 34047202940 scopus 로고    scopus 로고
    • Differences in the composition of intestinal Bifidobacterium species and the development of allergic diseases in infants in rural Japan
    • Suzuki S, Shimojo N, Tajiri Y, et al. Differences in the composition of intestinal Bifidobacterium species and the development of allergic diseases in infants in rural Japan. Clin Exp Allergy 2007; 37:506-511.
    • (2007) Clin Exp Allergy , vol.37 , pp. 506-511
    • Suzuki, S.1    Shimojo, N.2    Tajiri, Y.3
  • 36
    • 33845951414 scopus 로고    scopus 로고
    • Probiotics and prebiotic galactooligosaccharides in the prevention of allergic diseases: A randomized, double-blind, placebo-controlled trial
    • This was a large clinical intervention study showing a positive effect of probiotics and prebiotics in the prevention of atopic eczema
    • Kukkonen K, Savilahti E, Haahtela T, et al. Probiotics and prebiotic galactooligosaccharides in the prevention of allergic diseases: a randomized, double-blind, placebo-controlled trial. J Allergy Clin Immunol 2007; 119:192-198. This was a large clinical intervention study showing a positive effect of probiotics and prebiotics in the prevention of atopic eczema.
    • (2007) J Allergy Clin Immunol , vol.119 , pp. 192-198
    • Kukkonen, K.1    Savilahti, E.2    Haahtela, T.3
  • 37
    • 33645019411 scopus 로고    scopus 로고
    • Specificities of the fecal microbiota in inflammatory bowel disease
    • Sokol H, Seksik P, Rigottier-Gois L, et al. Specificities of the fecal microbiota in inflammatory bowel disease. Inflamm Bowel Dis 2006; 12:106-111.
    • (2006) Inflamm Bowel Dis , vol.12 , pp. 106-111
    • Sokol, H.1    Seksik, P.2    Rigottier-Gois, L.3
  • 38
    • 2342442430 scopus 로고    scopus 로고
    • Reduction in diversity of the colonic mucosa associated bacterial microflora in patients with active inflammatory bowel disease
    • Ott SJ, Musfeldt M, Wenderoth DF, et al. Reduction in diversity of the colonic mucosa associated bacterial microflora in patients with active inflammatory bowel disease. Gut 2004; 53:685-693.
    • (2004) Gut , vol.53 , pp. 685-693
    • Ott, S.J.1    Musfeldt, M.2    Wenderoth, D.F.3
  • 39
    • 30944466824 scopus 로고    scopus 로고
    • Manichanh C, Rigottier-Gois L, Bonnaud E, et al. Reduced diversity of faecal microbiota in Crohn's disease revealed by a metagenomic approach. Gut 2006; 55:205-211. In this outstanding investigation by metagenomic approach of the faecal flora in Crohn's disease the authors unveiled a marked reduction of biodiversity in patients in remission.
    • Manichanh C, Rigottier-Gois L, Bonnaud E, et al. Reduced diversity of faecal microbiota in Crohn's disease revealed by a metagenomic approach. Gut 2006; 55:205-211. In this outstanding investigation by metagenomic approach of the faecal flora in Crohn's disease the authors unveiled a marked reduction of biodiversity in patients in remission.
  • 40
    • 33750932588 scopus 로고    scopus 로고
    • Culture-independent analyses of temporal variation of the dominant fecal microbiota and targeted bacterial subgroups in Crohn's disease
    • Scanlan PD, Shanahan F, O'Mahony C, Marchesi JR. Culture-independent analyses of temporal variation of the dominant fecal microbiota and targeted bacterial subgroups in Crohn's disease. J Clin Microbiol 2006; 44:3980-3988.
    • (2006) J Clin Microbiol , vol.44 , pp. 3980-3988
    • Scanlan, P.D.1    Shanahan, F.2    O'Mahony, C.3    Marchesi, J.R.4
  • 42
    • 33845454742 scopus 로고    scopus 로고
    • Gut-associated bacterial microbiota in paediatric patients with inflammatory bowel disease
    • Conte MP, Schippa S, Zamboni I, et al. Gut-associated bacterial microbiota in paediatric patients with inflammatory bowel disease. Gut 2006; 55:1760-1767.
    • (2006) Gut , vol.55 , pp. 1760-1767
    • Conte, M.P.1    Schippa, S.2    Zamboni, I.3
  • 43
    • 24744444522 scopus 로고    scopus 로고
    • Search for localized dysbiosis in Crohn's disease ulcerations by temporal temperature gradient gel electrophoresis of 16S rRNA
    • Seksik P, Lepage P, de la Cochetiere MF, et al. Search for localized dysbiosis in Crohn's disease ulcerations by temporal temperature gradient gel electrophoresis of 16S rRNA. J Clin Microbiol 2005; 43:4654-4658.
    • (2005) J Clin Microbiol , vol.43 , pp. 4654-4658
    • Seksik, P.1    Lepage, P.2    de la Cochetiere, M.F.3
  • 44
    • 33747050143 scopus 로고    scopus 로고
    • The bacteriology of biopsies differs between newly diagnosed, untreated, Crohn's disease and ulcerative colitis patients
    • Bibiloni R, Mangold M, Madsen KL, et al. The bacteriology of biopsies differs between newly diagnosed, untreated, Crohn's disease and ulcerative colitis patients. J Med Microbiol 2006; 55:1141-1149.
    • (2006) J Med Microbiol , vol.55 , pp. 1141-1149
    • Bibiloni, R.1    Mangold, M.2    Madsen, K.L.3
  • 45
    • 33750956239 scopus 로고    scopus 로고
    • Differences between tissue-associated intestinal microfloras of patients with Crohn's disease and ulcerative colitis
    • Gophna U, Sommerfeld K, Gophna S, et al. Differences between tissue-associated intestinal microfloras of patients with Crohn's disease and ulcerative colitis. J Clin Microbiol 2006; 44:4136-4141.
    • (2006) J Clin Microbiol , vol.44 , pp. 4136-4141
    • Gophna, U.1    Sommerfeld, K.2    Gophna, S.3
  • 46
    • 12344249654 scopus 로고    scopus 로고
    • Synbiotic therapy (Bifidobacterium longum/Synergy 1) initiates resolution of inflammation in patients with active ulcerative colitis: A randomized controlled pilot trial
    • Furrie E, Macfarlane S, Kennedy A, et al. Synbiotic therapy (Bifidobacterium longum/Synergy 1) initiates resolution of inflammation in patients with active ulcerative colitis: a randomized controlled pilot trial. Gut 2005; 54:242-249.
    • (2005) Gut , vol.54 , pp. 242-249
    • Furrie, E.1    Macfarlane, S.2    Kennedy, A.3
  • 47
    • 34247096518 scopus 로고    scopus 로고
    • Oral oligofructose-enriched inulin supplementation in acute ulcerative colitis is well tolerated and associated with lowered faecal calprotectin
    • Casellas F, Borruel N, Torrejon A, et al. Oral oligofructose-enriched inulin supplementation in acute ulcerative colitis is well tolerated and associated with lowered faecal calprotectin. Aliment Pharmacol Ther 2007; 25:1061-1067.
    • (2007) Aliment Pharmacol Ther , vol.25 , pp. 1061-1067
    • Casellas, F.1    Borruel, N.2    Torrejon, A.3
  • 48
    • 33144470875 scopus 로고    scopus 로고
    • Clinical, microbiological, and immunological effects of fructo-oligosaccharide in patients with Crohn's disease
    • Lindsay JO, Whelan K, Stagg AJ, et al. Clinical, microbiological, and immunological effects of fructo-oligosaccharide in patients with Crohn's disease. Gut 2006; 55:348-355.
    • (2006) Gut , vol.55 , pp. 348-355
    • Lindsay, J.O.1    Whelan, K.2    Stagg, A.J.3
  • 49
    • 0037438711 scopus 로고    scopus 로고
    • Microbial colonization drives lymphocyte accumulation and differentiation in the follicle-associated epithelium of Peyer's patches
    • Yamanaka T, Helgeland L, Farstad IN, et al. Microbial colonization drives lymphocyte accumulation and differentiation in the follicle-associated epithelium of Peyer's patches. J Immunol 2003; 170:816-822.
    • (2003) J Immunol , vol.170 , pp. 816-822
    • Yamanaka, T.1    Helgeland, L.2    Farstad, I.N.3
  • 50
    • 33750326113 scopus 로고    scopus 로고
    • The love-hate relationship between bacterial polysaccharides and the host immune system
    • Excellent review on the tasks of the mucosal immune system in the gut for discriminating pathogen and nonpathogen microbia
    • Mazmanian SK, Kasper DL. The love-hate relationship between bacterial polysaccharides and the host immune system. Nat Rev Immunol 2006; 6:849-858. Excellent review on the tasks of the mucosal immune system in the gut for discriminating pathogen and nonpathogen microbia.
    • (2006) Nat Rev Immunol , vol.6 , pp. 849-858
    • Mazmanian, S.K.1    Kasper, D.L.2
  • 52
    • 1842732224 scopus 로고    scopus 로고
    • Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis
    • Viglietta V, Baecher-Allan C, Weiner HL, Hafler DA. Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis. J Exp Med 2004; 199:971-979.
    • (2004) J Exp Med , vol.199 , pp. 971-979
    • Viglietta, V.1    Baecher-Allan, C.2    Weiner, H.L.3    Hafler, D.A.4
  • 53
    • 33744904725 scopus 로고    scopus 로고
    • Secondary progressive in contrast to relapsing-remitting multiple sclerosis patients show a normal CD4+CD25+ regulatory T-cell function and FOXP3 expression
    • Venken K, Hellings N, Hensen K, et al. Secondary progressive in contrast to relapsing-remitting multiple sclerosis patients show a normal CD4+CD25+ regulatory T-cell function and FOXP3 expression. J Neurosci Res 2006; 83:1432-1446.
    • (2006) J Neurosci Res , vol.83 , pp. 1432-1446
    • Venken, K.1    Hellings, N.2    Hensen, K.3
  • 54
    • 1342308180 scopus 로고    scopus 로고
    • Relation of CD4+CD25+ regulatory T-cell suppression of allergen-driven T-cell activation to atopic status and expression of allergic disease
    • Ling EM, Smith T, Nguyen XD, et al. Relation of CD4+CD25+ regulatory T-cell suppression of allergen-driven T-cell activation to atopic status and expression of allergic disease. Lancet 2004; 363:608-615.
    • (2004) Lancet , vol.363 , pp. 608-615
    • Ling, E.M.1    Smith, T.2    Nguyen, X.D.3
  • 55
    • 3042594506 scopus 로고    scopus 로고
    • Allergen-responsive CD4+CD25+ regulatory T cells in children who have outgrown cow's milk allergy
    • Karlsson MR, Rugtveit J, Brandtzaeg P. Allergen-responsive CD4+CD25+ regulatory T cells in children who have outgrown cow's milk allergy. J Exp Med 2004; 199:1679-1688.
    • (2004) J Exp Med , vol.199 , pp. 1679-1688
    • Karlsson, M.R.1    Rugtveit, J.2    Brandtzaeg, P.3
  • 56
    • 20444434616 scopus 로고    scopus 로고
    • Peripheral and intestinal regulatory CD4+CD25high T cells in inflammatory bowel disease
    • Maul J, Loddenkemper C, Mundt P, et al. Peripheral and intestinal regulatory CD4+CD25high T cells in inflammatory bowel disease. Gastroenterology 2005; 128:1868-1878.
    • (2005) Gastroenterology , vol.128 , pp. 1868-1878
    • Maul, J.1    Loddenkemper, C.2    Mundt, P.3
  • 57
    • 33745275219 scopus 로고    scopus 로고
    • Functional CD4+CD25high regulatory T cells are enriched in the colonic mucosa of patients with active ulcerative colitis and increase with disease activity
    • Holmen N, Lundgren A, Lundin S, et al. Functional CD4+CD25high regulatory T cells are enriched in the colonic mucosa of patients with active ulcerative colitis and increase with disease activity. Inflamm Bowel Dis 2006; 12:447-456.
    • (2006) Inflamm Bowel Dis , vol.12 , pp. 447-456
    • Holmen, N.1    Lundgren, A.2    Lundin, S.3


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