Icariin promotes expression of PGC-1α, PPARα, and NRF-1 during cardiomyocyte differentiation of murine embryonic stem cells in vitro

Acta Pharmacologica Sinica

Volumn 28, Issue 10, 2007, Pages 1541-1549

  Ding, Ling ^a   Liang, Xing Guang ^a   Zhu, Dan Yan ^a   Lou, Yi Jia ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

Cardiomyocytes; Differentiation; Embryonic stem cells; Icariin; Mitochondrial; NRF 1; PGC 1 ; PPAR

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ALPHA ACTININ; ICARIIN; MITOGEN ACTIVATED PROTEIN KINASE P38; NUCLEAR RESPIRATORY FACTOR 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; TROPONIN T;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CONFOCAL LASER MICROSCOPY; EMBRYO; EMBRYONIC STEM CELL; HEART MUSCLE CELL; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CELL DIFFERENTIATION; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBRYONIC STEM CELLS; ENZYME INHIBITORS; EPIMEDIUM; FLAVONOIDS; IMIDAZOLES; MICE; MYOCYTES, CARDIAC; NUCLEAR RESPIRATORY FACTOR 1; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PLANTS, MEDICINAL; PPAR ALPHA; PYRIDINES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS;

EID: 34848828497     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1111/j.1745-7254.2007.00648.x     Document Type: Article

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