Left posterior hippocampal density reduction using VBM and stereological MRI procedures in schizophrenia

Schizophrenia Research

Volumn 96, Issue 1-3, 2007, Pages 62-71

  Rametti, Giuseppina ^a,c   Segarra, Nuria ^b   Junqué, Carme ^a,c   Bargalló, Nuria ^c,d   Caldú, Xavier ^a,c   Ibarretxe, Naroa ^a,c   Bernardo, Miguel ^b,c  

^a UNIVERSITY OF BARCELONA   (Spain)

^b HOSPITAL CLÍNIC   (Spain)

^c INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

^d Neuroradiology Section   (Spain)

Author keywords

Hippocampus; Memory; MRI; Neuropsychology; Schizophrenia; Stereology

Indexed keywords

ADULT; ARTICLE; BRAIN ATROPHY; BRAIN SIZE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HIPPOCAMPUS; HUMAN; LEARNING; MALE; MEMORY DISORDER; MORPHOMETRICS; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY; PRIORITY JOURNAL; SCHIZOPHRENIA; STEREOLOGY;

ADULT; BRAIN MAPPING; FEMALE; FUNCTIONAL LATERALITY; HIPPOCAMPUS; HUMANS; INTELLIGENCE TESTS; MAGNETIC RESONANCE IMAGING; MALE; NEUROPSYCHOLOGICAL TESTS; REFERENCE VALUES; SCHIZOPHRENIA; SCHIZOPHRENIC PSYCHOLOGY;

EID: 34848823399     PISSN: 09209964     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.schres.2007.04.034     Document Type: Article

References (58)

1. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 4th ed (1994) Washington, DC.
2. Andreasen N.C. The Scale for Assessment of Negative Symptoms (SANS) (1983), University of Iowa, Iowa City, IA
3. Andreasen N.C. The Scale for Assessment of Positive Symptoms (SAPS) (1984), University of Iowa, Iowa City, IA
4. Antonova E., Sharma T., Morris R., and Kumari V. The relationship between brain structure and neurocognition in schizophrenia: a selective review. Schizophr. Res. 70 2-3 (2004) 117-145
5. Arnold S.E., Franz B.R., Gur R.C., Gur R.E., Shapiro R.M., Moberg P.J., et al. Smaller neuron size in schizophrenia in hippocampal subfields that mediate cortical-hippocampal interactions. Am. J. Psychiatry 152 5 (1995) 738-748
6. Ashburner J., and Friston K. Multimodal image coregistration and partitioning-a unified framework. NeuroImage 6 3 (1997) 209-217
7. Becker T., Elmer K., Schneider F., Schneider M., Grodd W., Bartels M., Heckers S., and Beckman H. Confirmation of reduced temporal limbic structure volume on magnetic resonance imaging in male patients with schizophrenia. Psychiatry Res. Neuroimaging 67 2 (1996) 135-143
8. Benes F.M., Sorensen I., and Bird E. Reduced neuronal size in posterior hippocampus of schizophrenics patients. Schizophr. Bull. 17 4 (1991) 597-608
9. Bogerts B., Meertz E., and Schonfeldt-Bausch R. Basal ganglia and limbic system pathology in schizophrenia. A morphometric study of brain volume and shrinkage. Arch. Gen. Psychiatry 42 8 (1985) 784-791
10. Bogerts B., Lieberman J.A., Ashtari M., Bilder R.M., Degreef G., Lerner G., Johns C., and Masiar S. Hippocampus-amygdala volumes and psychopathology in chronic schizophrenia. Biol. Psychiatry 33 4 (1993) 236-246
11. Buchanan R.W., Breier A., Kirkpatrick B., Elkashef A., Munson R.C., Gellad F., et al. Structural abnormalities in deficit and nondeficit schizophrenia. Am. J. Psychiatry 150 1 (1993) 59-65
12. Chakos M.H., Lieberman J.A., Bilder R.M., Borenstein M., Lerne G., Bogerts B., et al. Increase in caudate nuclei volumes of first-episode schizophrenic patients taking antipsychotic drugs. Am. J. Psychiatry 151 10 (1994) 1430-1436
13. Chakos M.H., Shirakawa O., Lieberman J., Lee H., Bilder R., and Tamminga C.A. Striatal enlargement in rats chronically treated with neuroleptic. Biol. Psychiatry 15 8 (1998) 675-684
14. Csernansky J.G., Joshi S., Wang L., Haller J.W., Gado M., Miller J.P., et al. Hippocampal morphometry in schizophrenia by high dimensional brain mapping. Proc. Natl. Acad. Sci. 95 19 (1998) 11406-11411
15. Delisi L.E., Hoff A.L., Schwartz J.E., Shields G.W., Halthore S.N., Gupta S.M., Henn F.A., and Anand A.K. Brain morphology in first-episode schizophrenic-like psychotic patients: a quantitative magnetic resonance imaging study. Biol. Psychiatry 29 5 (1991) 519
16. DeLisi L.E., Tew W., Xie S., Hoff A.L., Sakuma M., Kushner M., et al. A prospective follow-up study of brain morphology and cognition in first-episode schizophrenic patients: preliminary findings. Biol. Psychiatry 15 6 (1995) 349-360
17. Goldberg T.E., Torrey E.F., Berman K.F., and Weinberger D.R. Relations between neuropsychological performance and brain morphological and physiological measures in monozygotic twins discordant for schizophrenia. Psychiatry Res. 55 1 (1994) 51-61
18. Goldman-Rakic P.S., Selemon L.D., and Schwartz M. Dual pathways connecting the dorsolateral prefrontal cortex with the hippocampal formation and parahippocampal cortex in the rhesus monkey. Neuroscience 12 3 (1984) 719-743
19. Good C.D., Johnsrude I.S., Ashburner J., Henson R.N.A., Friston K.L., and Frackowiak S.J. A voxel-based morphometry study of ageing in 465 normal adult human brains. NeuroImage 14 (2001) 21-36
20. Gur R.E., Turetsky B.I., Cowell P.E., Finkelman C., Maany V., Grossman R.I., Arnold S.E., Bilker W.B., and Gur R. Temporolimbic volume reductions in schizophrenia. Arch. Gen. Psychiatry 57 8 (2000) 769-775
21. Harrison P.J., and Eastwood S.L. Neuropathological studies of synaptic connectivity in the hippocampal formation in schizophrenia. Hippocampus 11 5 (2001) 508-519
22. Hirayasu Y., Shenton M.E., Salisbury D.F., Dickey C.C., Fischer I.A., Mazzoni P., Kisler T., Arakaki H., Kwon J.S., Anderson J.E., Yurgelun-Todd D., Tohen M., and McCarley R.W. Lower left temporal lobe MRI volumes in patients with first-episode schizophrenia compared with psychotic patients with first-episode affective disorder and normal subjects. Am. J. Psychiatry 155 10 (1998) 1384-1391
23. Honea R., Crow T.J., Passingham D., and Mackay C.E. Regional deficits in brain volume in schizophrenia: a meta-analysis of voxel-based morphometry studies. Am. J. Psychiatry 162 12 (2005) 2233-2245
24. Jeste D.V., and Lohr J.B. Hippocampal pathologic findings in schizophrenia. A morphometric study. Arch. Gen. Psychiatry 46 11 (1989) 1019-1024
25. Kalus P., Buri C., Slotboom J., Gralla J., Remonda L., Dierks T., Strik W.K., Schroth G., and Kiefer C. Volumetry and diffusion tensor imaging of hippocampal subregions in schizophrenia. NeuroReport 15 5 (2004) 867-871
26. Laakso M.P., Tiihonen J., Syvalahti E., Vilkman H., Laakso A., Alakare B., et al. A morphometric MRI study of the hippocampus in first-episode, neuroleptic-naive schizophrenia. Schizophr. Res. 50 1-2 (2001) 3-7
27. Lezak M.D., Howieson D.B., and Loring D.W. Neuropsychological Assessment. 4th edition (2004), Oxford University Press
28. Luders E., Narr K.L., Thompson P.M., Woods R.P., Rex D.E., Jancke L., Steinmetz H., and Toga A.W. Mapping cortical gray matter in the young adult brain: effects of gender. NeuroImage 26 2 (2005) 493-501
29. Maldjian J.A., Laurienti P.J., Kraft R.A., and Burdette J.H. An automated method for neuroanatomic and cytoarchitectonic atlas-based interrogation of fMRI data sets. NeuroImage 19 (2003) 1233-1239
30. Marsh L., Lim K.O., Hoff A.L., Harris D., Beal M., Minn K., Faustman W.O., Csernansky J.G., Sullivan E.V., and Pfefferbaum A. Severity of schizophrenia and magnetic resonance imaging abnormalities: a comparison of state and veterans hospital patients. Biol. Psychiatry 45 1 (1999) 49-61
31. McCarley R.W., Wible C.G., Frumin M., Hirayasu Y., Levitt J.J., Fischer I.A., et al. MRI anatomy of schizophrenia. Biol. Psychiatry 45 9 (1999) 1099-1119
32. McClure R.K., Phillips I., Jazayerli R., Barnett A., Coppola R., and Weinberger D.R. Regional change in brain morphometry in schizophrenia associated with antipsychotic treatment. Psychiatry Res. 1 2-3 (2006) 121-132
33. Mechelli A., Price C.J., Friston K.J., and Ashburener J. Voxel-based morphometry of the human brain: methods and applications. Curr. Med. Imaging Rev. 1 1 (2005) 1-9
34. Narr K., Thompson P., Sharma T., Moussai J., Zoumalan C., Rayman J., et al. Three-dimensional mapping of gyral shape and cortical surface asymmetries in schizophrenia: gender effects. Am. J. Psychiatry 158 2 (2001) 244-255
35. Narr K.L., Thompson P.M., Szeszko P., Robinson D., Jang S., Woods R.P., et al. Regional specificity of hippocampal volume reductions in first-episode schizophrenia. NeuroImage 21 4 (2004) 1563-1575
36. Nelson M.D., Saykin A.J., Flashman L.A., and Riordan H.J. Hippocampal volume reduction in schizophrenia as assessed by magnetic resonance imaging: a meta-analytic study. Arch. Gen. Psychiatry 55 5 (1998) 433-440
37. Niemann K., Hammers A., Coenen V.A., Thron A., and Klosterjötter J. Evidence of a smaller left hippocampus and left temporal horn in both patients with first episode schizophrenia and normal control subjects. Psychiatry Res. 99 2 (2000) 93-110
38. Overall J.E., and Gorman D.L. The brief psychiatric rating scale. Psychol. Rep. 10 (1962) 799-7113
39. Pantel J., O'Leary D.S., Cretsinger K., Bockholt H.J., Keefe H., Magnotta V.A., et al. A new method for the in vivo volumetric measurement of the human hippocampus with high neuroanatomical accuracy. Hippocampus 10 6 (2000) 752-758
40. Pegues M.P., Rogers L.J., Amend D., Vinogradov S., and Deicken R.F. Anterior hippocampal volume reduction in male patients with schizophrenia. Schizophr. Res. 60 2-3 (2003) 105-115
41. Rajarethinam R., Dequardo J.R., Miedler J., Arndt S., Kirbat R., Brunberg J.A., and Tandon R. Hippocampus and amygdala in schizophrenia: assessment of the relationship of neuroanatomy to psychopathology. Psychiatry Res. 108 2 (2001) 79-87
42. Ronan L., Colin P.D., Delanty N., Thornton J., and Fitzsimons M. Quantitative MRI: a reliable protocol for measurement of cerebral gyrification using stereology. Magn. Reson. Imaging 24 3 (2006) 265-272
43. Sanfilipo M., Lafargue T., Rusinek H., Arena L., Loneragan C., Lautin A., Rotrosen J., and Wolkin A. Cognitive performance in schizophrenia: relationship to regional brain volumes and psychiatric symptoms. Psychiatry Res. 116 1-2 (2002) 1-23
44. Shapleske J., Rossell S.L., Chitnis X.A., Suckling J., Simmons A., Bullmore E.T., Woodruff P.W., and David A.S. A computational morphometric MRI study of schizophrenia: effects of hallucinations. Cereb. Cortex 12 12 (2002) 1331-1341
45. Shenton M.E., Dickey C.C., Frumin M., and McCarley R.W. A review of MRI findings in schizophrenia. Schizophr. Res. 49 1-2 (2001) 1-52
46. Shenton M.E., Gerig G., McCarley R.W., Szekely G., and Kikinis R. Amygdala-hippocampal shape differences in schizophrenia: the application of 3D shape models to volumetric MR data. Psychiatry Res. 115 1-2 (2002) 15-35
47. Styner M., Lieberman J.A., Pantazis D., and Gerig G. Boundary and medial shape analysis of the hippocampus in schizophrenia. Med. Image Anal. 8 3 (2004) 197-203
48. Sullivan E.V., Marsh L., Mathalon D.H., Lim K.O., and Pfefferbaum A. Anterior hippocampal volume deficits in nonamnesic, aging chronic alcoholics. Alcohol., Clin. Exp. Res. 19 1 (1995) 110-122
49. Szeszko P.R., Goldberg E., Gunduz-Bruce H., Ashtari M., Robinson D., Malhotra A.K., et al. Smaller anterior hippocampal formation volume in antipsychotic-naive patients with first-episode schizophrenia. Am. J. Psychiatry 160 12 (2003) 2190-2197
50. Torres I.J., Flashman L.A., O'Leary D.S., Swayze V., and Andreasen N.C. Lack of an association between delayed memory and hippocampal and temporal lobe size in patients with schizophrenia and healthy controls. Biol. Psychiatry 42 12 (1997) 1087-1096
51. Van Petten C. Relationship between hippocampal volume and memory ability in healthy individuals across the lifespan: review and meta-analysis. Neuropsychologia 42 10 (2004) 1394-1413
52. Velakoulis D., Stuart G.W., Wood S.J., Smith D.J., Brewer W.J., Desmond P., et al. Selective bilateral hippocampal volume loss in chronic schizophrenia. Biol. Psychiatry 50 7 (2001) 531-539
53. Wang L., Joshi S.C., Miller M.I., and Csernansky J.G. Statistical analysis of hippocampal asymmetry in schizophrenia. NeuroImage 14 3 (2001) 531-545
54. Weiss A.P., Dewitt I., Goff D., Ditman T., and Heckers S. Anterior and posterior hippocampal volumes in schizophrenia. Schizophr. Res. 73 1 (2005) 103-112
55. Wright I.C., Rabe-Hesketh S., Woodruff P.W., David A.S., Murray R.M., and Bullmore E.T. Meta-analysis of regional brain volumes in schizophrenia. Am. J. Psychiatry 157 1 (2000) 16-25
56. Yamasue H., Iwanami A., Hirayasu Y., Yamada H., Abe O., Kuroki N., et al. Localized volume reduction in prefrontal, temporolimbic, and paralimbic regions in schizophrenia: an MRI parcellation study. Psychiatry Res. 131 3 (2004) 195-207
57. Zaidel D.W., Esiri M.M., and Harrison P.J. Size, shape, and orientation of neurons in the left and right hippocampus: investigation of normal asymmetries and alterations in schizophrenia. Am. J. Psychiatry 154 6 (1997) 812-818
58. Zaidel D.W., Esiri M.M., and Harrison P.J. The hippocampus in schizophrenia: lateralized increase in neuronal density and altered cytoarchitectural asymmetry. Psychol. Med. 27 3 (1997) 703-713