-
1
-
-
0027310539
-
Deficiency of the GPI anchor caused by a somatic mutation of the PIG-A gene in paroxysmal nocturnal hemoglobinuria
-
Takeda, J., Miyata, T. and Kawagoe, K. (1993) Deficiency of the GPI anchor caused by a somatic mutation of the PIG-A gene in paroxysmal nocturnal hemoglobinuria. Cell, 73:4, pp. 703-711.
-
(1993)
Cell
, vol.73
, Issue.4
, pp. 703-711
-
-
Takeda, J.1
Miyata, T.2
Kawagoe, K.3
-
2
-
-
0028802443
-
Natural history of paroxysmal nocturnal hemoglobinuria
-
Hillmen, P., Lewis, SM and Bessler, M. (1995) Natural history of paroxysmal nocturnal hemoglobinuria. N Engl J Med, 333:19, pp. 1253-1258.
-
(1995)
N Engl J Med
, vol.333
, Issue.19
, pp. 1253-1258
-
-
Hillmen, P.1
Lewis, S.M.2
Bessler, M.3
-
3
-
-
33748904355
-
The complement inhibitor eculizumab in paroxysmal nocturnal hemoglobinuria
-
Hillmen, P., Young, NS and Schubert, J. (2006) The complement inhibitor eculizumab in paroxysmal nocturnal hemoglobinuria. N Engl J Med, 355:12, pp. 1233-1243.
-
(2006)
N Engl J Med
, vol.355
, Issue.12
, pp. 1233-1243
-
-
Hillmen, P.1
Young, N.S.2
Schubert, J.3
-
4
-
-
0028057807
-
Paroxysmal nocturnal haemoglobinuria (PNH) is caused by somatic mutations in the PIG-A gene
-
Bessler, M., Mason, PJ and Hillmen, P. (1994) Paroxysmal nocturnal haemoglobinuria (PNH) is caused by somatic mutations in the PIG-A gene. EMBO J, 13:1, pp. 110-117.
-
(1994)
EMBO J
, vol.13
, Issue.1
, pp. 110-117
-
-
Bessler, M.1
Mason, P.J.2
Hillmen, P.3
-
5
-
-
0028802885
-
Genetic defects underlying paroxysmal nocturnal hemoglobinuria that arises out of aplastic anemia
-
Nagarajan, S., Brodsky, RA and Young, NS (1995) Genetic defects underlying paroxysmal nocturnal hemoglobinuria that arises out of aplastic anemia. Blood, 86:12, pp. 4656-4661.
-
(1995)
Blood
, vol.86
, Issue.12
, pp. 4656-4661
-
-
Nagarajan, S.1
Brodsky, R.A.2
Young, N.S.3
-
6
-
-
0032898217
-
Genotypic, immunophenotypic and clinical features of Thai patients with paroxysmal nocturnal haemoglobinuria
-
Pramoonjago, P., Pakdeesuwan, K. and Siripanyaphinyo, U. (1999) Genotypic, immunophenotypic and clinical features of Thai patients with paroxysmal nocturnal haemoglobinuria. Br J Haematol, 105:2, pp. 497-504.
-
(1999)
Br J Haematol
, vol.105
, Issue.2
, pp. 497-504
-
-
Pramoonjago, P.1
Pakdeesuwan, K.2
Siripanyaphinyo, U.3
-
7
-
-
0028885951
-
Mutations in the PIG-A gene causing paroxysmal nocturnal hemoglobinuria are mainly of the frameshift type
-
Nafa, K., Mason, PJ and Hillmen, P. (1995) Mutations in the PIG-A gene causing paroxysmal nocturnal hemoglobinuria are mainly of the frameshift type. Blood, 86:12, pp. 4650-4655.
-
(1995)
Blood
, vol.86
, Issue.12
, pp. 4650-4655
-
-
Nafa, K.1
Mason, P.J.2
Hillmen, P.3
-
8
-
-
0028897279
-
Somatic mutations of the PIG-A gene found in Japanese patients with paroxysmal nocturnal hemoglobinuria
-
Yamada, N., Miyata, T. and Maeda, K. (1995) Somatic mutations of the PIG-A gene found in Japanese patients with paroxysmal nocturnal hemoglobinuria. Blood, 85:4, pp. 885-892.
-
(1995)
Blood
, vol.85
, Issue.4
, pp. 885-892
-
-
Yamada, N.1
Miyata, T.2
Maeda, K.3
-
9
-
-
18544394069
-
Impaired growth and elevated fas receptor expression in PIGA(+) stem cells in primary paroxysmal nocturnal hemoglobinuria
-
Chen, R., Nagarajan, S. and Prince, GM (2000) Impaired growth and elevated fas receptor expression in PIGA(+) stem cells in primary paroxysmal nocturnal hemoglobinuria. J Clin Invest, 106:5, pp. 689-696.
-
(2000)
J Clin Invest
, vol.106
, Issue.5
, pp. 689-696
-
-
Chen, R.1
Nagarajan, S.2
Prince, G.M.3
-
10
-
-
0025233715
-
The complement-inhibitory activity of CD59 resides in its capacity to block incorporation of C9 into membrane C5b-9
-
Rollins, SA and Sims, PJ (1990) The complement-inhibitory activity of CD59 resides in its capacity to block incorporation of C9 into membrane C5b-9. J Immunol, 144:9, pp. 3478-3483.
-
(1990)
J Immunol
, vol.144
, Issue.9
, pp. 3478-3483
-
-
Rollins, S.A.1
Sims, P.J.2
-
11
-
-
0021910555
-
Amelioration of lytic abnormalities of paroxysmal nocturnal hemoglobinuria with decay-accelerating factor
-
Medof, ME, Kinoshita, T. and Silber, R. (1985) Amelioration of lytic abnormalities of paroxysmal nocturnal hemoglobinuria with decay-accelerating factor. Proc Natl Acad Sci USA, 82:9, pp. 2980-2984.
-
(1985)
Proc Natl Acad Sci USA
, vol.82
, Issue.9
, pp. 2980-2984
-
-
Medof, M.E.1
Kinoshita, T.2
Silber, R.3
-
12
-
-
0025784367
-
Molecular basis of the enhanced susceptibility of the erythrocytes of paroxysmal nocturnal hemoglobinuria to hemolysis in acidified serum
-
Wilcox, LA, Ezzell, JL and Bernshaw, NJ (1991) Molecular basis of the enhanced susceptibility of the erythrocytes of paroxysmal nocturnal hemoglobinuria to hemolysis in acidified serum. Blood, 78:3, pp. 820-829.
-
(1991)
Blood
, vol.78
, Issue.3
, pp. 820-829
-
-
Wilcox, L.A.1
Ezzell, J.L.2
Bernshaw, N.J.3
-
13
-
-
15944398355
-
The clinical sequelae of intravascular hemolysis and extracellular plasma hemoglobin: A novel mechanism of human disease
-
Rother, RP, Bell, L. and Hillmen, P. (2005) The clinical sequelae of intravascular hemolysis and extracellular plasma hemoglobin: A novel mechanism of human disease. JAMA, 293:13, pp. 1653-1662.
-
(2005)
JAMA
, vol.293
, Issue.13
, pp. 1653-1662
-
-
Rother, R.P.1
Bell, L.2
Hillmen, P.3
-
14
-
-
18844446494
-
Platelet-vessel wall interactions in the microcirculation
-
Tailor, A., Cooper, D. and Granger, DN (2005) Platelet-vessel wall interactions in the microcirculation. Microcirculation, 12:3, pp. 275-285.
-
(2005)
Microcirculation
, vol.12
, Issue.3
, pp. 275-285
-
-
Tailor, A.1
Cooper, D.2
Granger, D.N.3
-
15
-
-
0036908599
-
Cell-free hemoglobin limits nitric oxide bioavailability in sickle-cell disease
-
Reiter, CD, Wang, X. and Tanus-Santos, JE (2002) Cell-free hemoglobin limits nitric oxide bioavailability in sickle-cell disease. Nat Med, 8:12, pp. 1383-1389.
-
(2002)
Nat Med
, vol.8
, Issue.12
, pp. 1383-1389
-
-
Reiter, C.D.1
Wang, X.2
Tanus-Santos, J.E.3
-
16
-
-
3042789125
-
Natural history of paroxysmal nocturnal haemoglobinuria using modern diagnostic assays
-
Moyo, VM, Mukhina, GL and Garrett, ES (2004) Natural history of paroxysmal nocturnal haemoglobinuria using modern diagnostic assays. Br J Haematol, 126:1, pp. 133-138.
-
(2004)
Br J Haematol
, vol.126
, Issue.1
, pp. 133-138
-
-
Moyo, V.M.1
Mukhina, G.L.2
Garrett, E.S.3
-
17
-
-
0033864326
-
A phase I study of oxidized raffinose cross-linked human hemoglobin
-
Carmichael, FJ, Ali, AC and Campbell, JA (2000) A phase I study of oxidized raffinose cross-linked human hemoglobin. Crit Care Med, 28:7, pp. 2283-2292.
-
(2000)
Crit Care Med
, vol.28
, Issue.7
, pp. 2283-2292
-
-
Carmichael, F.J.1
Ali, A.C.2
Campbell, J.A.3
-
18
-
-
0017840440
-
A clinical safety trial of stroma-free hemoglobin
-
Savitsky, JP, Doczi, J. and Black, J. (1978) A clinical safety trial of stroma-free hemoglobin. Clin Pharmacol Ther, 23:1, pp. 73-80.
-
(1978)
Clin Pharmacol Ther
, vol.23
, Issue.1
, pp. 73-80
-
-
Savitsky, J.P.1
Doczi, J.2
Black, J.3
-
19
-
-
0032921865
-
Controlled safety study of a hemoglobin-based oxygen carrier, DCLHb, in acute ischemic stroke
-
Saxena, R., Wijnhoud, AD and Carton, H. (1999) Controlled safety study of a hemoglobin-based oxygen carrier, DCLHb, in acute ischemic stroke. Stroke, 30:5, pp. 993-996.
-
(1999)
Stroke
, vol.30
, Issue.5
, pp. 993-996
-
-
Saxena, R.1
Wijnhoud, A.D.2
Carton, H.3
-
20
-
-
33749433931
-
The many antithrombotic actions of nitric oxide
-
Tziros, C. and Freedman, JE (2006) The many antithrombotic actions of nitric oxide. Curr Drug Targets, 7:10, pp. 1243-1251.
-
(2006)
Curr Drug Targets
, vol.7
, Issue.10
, pp. 1243-1251
-
-
Tziros, C.1
Freedman, J.E.2
-
21
-
-
0033562372
-
Elevated levels of circulating procoagulant microparticles in patients with paroxysmal nocturnal hemoglobinuria and aplastic anemia
-
Hugel, B. and Socie, G. (1999) Elevated levels of circulating procoagulant microparticles in patients with paroxysmal nocturnal hemoglobinuria and aplastic anemia. Blood, 93:10, pp. 3451-3456.
-
(1999)
Blood
, vol.93
, Issue.10
, pp. 3451-3456
-
-
Hugel, B.1
Socie, G.2
-
22
-
-
18244426909
-
Plasmatic coagulation and fibrinolytic system alterations in PNH: Relation to clone size
-
Grunewald, M., Siegemund, A. and Grunewald, A. (2003) Plasmatic coagulation and fibrinolytic system alterations in PNH: Relation to clone size. Blood Coagul Fibrinolysis, 14:7, pp. 685-695.
-
(2003)
Blood Coagul Fibrinolysis
, vol.14
, Issue.7
, pp. 685-695
-
-
Grunewald, M.1
Siegemund, A.2
Grunewald, A.3
-
23
-
-
33645649340
-
A GPI-anchored co-receptor for tissue factor pathway inhibitor controls its intracellular trafficking and cell surface expression
-
Maroney, SA, Cunningham, AC and Ferrel, J. (2006) A GPI-anchored co-receptor for tissue factor pathway inhibitor controls its intracellular trafficking and cell surface expression. J Thromb Haemost, 4:5, pp. 1114-1124.
-
(2006)
J Thromb Haemost
, vol.4
, Issue.5
, pp. 1114-1124
-
-
Maroney, S.A.1
Cunningham, A.C.2
Ferrel, J.3
-
24
-
-
0033609114
-
Clonal populations of hematopoietic cells with paroxysmal nocturnal hemoglobinuria genotype and phenotype are present in normal individuals
-
Araten, DJ, Nafa, K. and Pakdeesuwan, K. (1999) Clonal populations of hematopoietic cells with paroxysmal nocturnal hemoglobinuria genotype and phenotype are present in normal individuals. Proc Natl Acad Sci USA, 96:9, pp. 5209-5214.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, Issue.9
, pp. 5209-5214
-
-
Araten, D.J.1
Nafa, K.2
Pakdeesuwan, K.3
-
25
-
-
18544381754
-
PIG-A mutations in normal hematopoiesis
-
Mukhina, GL and Piantadosi, S. (2005) PIG-A mutations in normal hematopoiesis. Blood, 105:10, pp. 3848-3854.
-
(2005)
Blood
, vol.105
, Issue.10
, pp. 3848-3854
-
-
Mukhina, G.L.1
Piantadosi, S.2
-
26
-
-
0030955185
-
Murine embryonic stem cells without pig-a gene activity are competent for hematopoiesis with the PNH phenotype but not for clonal expansion
-
Rosti, V., Tremml, G. and Soares, V. (1997) Murine embryonic stem cells without pig-a gene activity are competent for hematopoiesis with the PNH phenotype but not for clonal expansion. J Clin Invest, 100:5, pp. 1028-1036.
-
(1997)
J Clin Invest
, vol.100
, Issue.5
, pp. 1028-1036
-
-
Rosti, V.1
Tremml, G.2
Soares, V.3
-
27
-
-
0029873584
-
Glycosylphosphatidylinositol-anchor-deficient mice: Implications for clonal dominance of mutant cells in paroxysmal nocturnal hemoglobinuria
-
Kawagoe, K., Kitamura, D. and Okabe, M. (1996) Glycosylphosphatidylinositol-anchor-deficient mice: Implications for clonal dominance of mutant cells in paroxysmal nocturnal hemoglobinuria. Blood, 87:9, pp. 3600-3606.
-
(1996)
Blood
, vol.87
, Issue.9
, pp. 3600-3606
-
-
Kawagoe, K.1
Kitamura, D.2
Okabe, M.3
-
28
-
-
0030739941
-
Resistance to apoptosis caused by PIG-A gene mutations in paroxysmal nocturnal hemoglobinuria
-
Brodsky, RA, Vala, MS and Barber, JP (1997) Resistance to apoptosis caused by PIG-A gene mutations in paroxysmal nocturnal hemoglobinuria. Proc Natl Acad Sci USA, 94:16, pp. 8756-8760.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, Issue.16
, pp. 8756-8760
-
-
Brodsky, R.A.1
Vala, M.S.2
Barber, J.P.3
-
29
-
-
31544482132
-
Immunoselection by natural killer cells of PIGA mutant cells missing stress-inducible ULBP
-
Hanaoka, N., Kawaguchi, T. and Horikawa, K. (2006) Immunoselection by natural killer cells of PIGA mutant cells missing stress-inducible ULBP. Blood, 107:3, pp. 1184-1191.
-
(2006)
Blood
, vol.107
, Issue.3
, pp. 1184-1191
-
-
Hanaoka, N.1
Kawaguchi, T.2
Horikawa, K.3
-
30
-
-
33845494914
-
Molecular basis of clonal expansion of hematopoiesis in 2 patients with paroxysmal nocturnal hemoglobinuria (PNH)
-
Inoue, N., Izui-Sarumaru, T. and Murakami, Y. (2006) Molecular basis of clonal expansion of hematopoiesis in 2 patients with paroxysmal nocturnal hemoglobinuria (PNH). Blood, 108:13, pp. 4232-4236.
-
(2006)
Blood
, vol.108
, Issue.13
, pp. 4232-4236
-
-
Inoue, N.1
Izui-Sarumaru, T.2
Murakami, Y.3
-
31
-
-
0035058599
-
Relative increase of granulocytes with a paroxysmal nocturnal haemoglobinuria phenotype in aplastic anaemia patients: The high prevalence at diagnosis
-
Wang, H., Chuhjo, T. and Yamazaki, H. (2001) Relative increase of granulocytes with a paroxysmal nocturnal haemoglobinuria phenotype in aplastic anaemia patients: The high prevalence at diagnosis. Eur J Haematol, 66:3, pp. 200-205.
-
(2001)
Eur J Haematol
, vol.66
, Issue.3
, pp. 200-205
-
-
Wang, H.1
Chuhjo, T.2
Yamazaki, H.3
-
32
-
-
0035724869
-
Multilineage glycosylphosphatidylinositol anchor-deficient haematopoiesis in untreated aplastic anaemia
-
Mukhina, GL, Buckley, JT and Barber, JP (2001) Multilineage glycosylphosphatidylinositol anchor-deficient haematopoiesis in untreated aplastic anaemia. Br J Haematol, 115:2, pp. 476-482.
-
(2001)
Br J Haematol
, vol.115
, Issue.2
, pp. 476-482
-
-
Mukhina, G.L.1
Buckley, J.T.2
Barber, J.P.3
-
33
-
-
0033592318
-
Paroxysmal nocturnal hemoglobinuria cells in patients with bone marrow failure syndromes
-
Dunn, DE, Tanawattanacharoen, P. and Boccuni, P. (1999) Paroxysmal nocturnal hemoglobinuria cells in patients with bone marrow failure syndromes. Ann Intern Med, 131:6, pp. 401-408.
-
(1999)
Ann Intern Med
, vol.131
, Issue.6
, pp. 401-408
-
-
Dunn, D.E.1
Tanawattanacharoen, P.2
Boccuni, P.3
-
34
-
-
33644898822
-
Normal patterns of expression of glycosylphosphatidylinositol-anchored proteins on different subsets of peripheral blood cells: A frame of reference for the diagnosis of paroxysmal nocturnal hemoglobinuria
-
Hernandez-Campo, PM, Almeida, J. and Sanchez, ML (2006) Normal patterns of expression of glycosylphosphatidylinositol-anchored proteins on different subsets of peripheral blood cells: A frame of reference for the diagnosis of paroxysmal nocturnal hemoglobinuria. Cytometry B Clin Cytom, 70:2, pp. 71-81.
-
(2006)
Cytometry B Clin Cytom
, vol.70
, Issue.2
, pp. 71-81
-
-
Hernandez-Campo, P.M.1
Almeida, J.2
Sanchez, M.L.3
-
35
-
-
0034502010
-
Improved detection and characterization of paroxysmal nocturnal hemoglobinuria using fluorescent aerolysin
-
Brodsky, RA and Mukhina, GL (2000) Improved detection and characterization of paroxysmal nocturnal hemoglobinuria using fluorescent aerolysin. Am J Clin Pathol, 114:3, pp. 459-466.
-
(2000)
Am J Clin Pathol
, vol.114
, Issue.3
, pp. 459-466
-
-
Brodsky, R.A.1
Mukhina, G.L.2
-
36
-
-
0032936695
-
Bone marrow transplants for paroxysmal nocturnal haemoglobinuria
-
Saso, R., Marsh, J. and Cevreska, L. (1999) Bone marrow transplants for paroxysmal nocturnal haemoglobinuria. Br J Haematol, 104:2, pp. 392-396.
-
(1999)
Br J Haematol
, vol.104
, Issue.2
, pp. 392-396
-
-
Saso, R.1
Marsh, J.2
Cevreska, L.3
-
37
-
-
9144244793
-
Hematopoietic cell transplantation from related and unrelated donors after minimal conditioning as a curative treatment modality for severe paroxysmal nocturnal hemoglobinuria
-
Hegenbart, U., Niederwieser, D. and Forman, S. (2003) Hematopoietic cell transplantation from related and unrelated donors after minimal conditioning as a curative treatment modality for severe paroxysmal nocturnal hemoglobinuria. Biol Blood Marrow Transplant, 9:11, pp. 689-697.
-
(2003)
Biol Blood Marrow Transplant
, vol.9
, Issue.11
, pp. 689-697
-
-
Hegenbart, U.1
Niederwieser, D.2
Forman, S.3
-
38
-
-
0842285673
-
In vitro and in vivo evidence of PNH cell sensitivity to immune attack after nonmyeloablative allogeneic hematopoietic cell transplantation
-
Takahashi, Y., McCoy Jr., JP and Carvallo, C. (2004) In vitro and in vivo evidence of PNH cell sensitivity to immune attack after nonmyeloablative allogeneic hematopoietic cell transplantation. Blood, 103:4, pp. 1383-1390.
-
(2004)
Blood
, vol.103
, Issue.4
, pp. 1383-1390
-
-
Takahashi, Y.1
McCoy Jr., J.P.2
Carvallo, C.3
-
39
-
-
0026588963
-
Marrow transplantation for paroxysmal nocturnal hemoglobinuria
-
Kawahara, K., Witherspoon, RP and Storb, R. (1992) Marrow transplantation for paroxysmal nocturnal hemoglobinuria. Am J Hematol, 39:4, pp. 283-288.
-
(1992)
Am J Hematol
, vol.39
, Issue.4
, pp. 283-288
-
-
Kawahara, K.1
Witherspoon, R.P.2
Storb, R.3
-
40
-
-
10744228553
-
Effect of eculizumab on hemolysis and transfusion requirements in patients with paroxysmal nocturnal hemoglobinuria
-
Hillmen, P., Hall, C. and Marsh, JC (2004) Effect of eculizumab on hemolysis and transfusion requirements in patients with paroxysmal nocturnal hemoglobinuria. N Engl J Med, 350:6, pp. 552-559.
-
(2004)
N Engl J Med
, vol.350
, Issue.6
, pp. 552-559
-
-
Hillmen, P.1
Hall, C.2
Marsh, J.C.3
|