Failure of puberty in Egyptian beta thalassemic patients: Experience in north east region - Dakahlia province

Hematology

Volumn 12, Issue 5, 2007, Pages 449-456

  Abdelrazik, Nabil ^a   Ghanem, Hossam ^a  

^a MANSOURA UNIVERSITY   (Egypt)

Author keywords

Beta thalassemia major; Hypogonadotropic hypogonadism; Puberty; Thalassemic patients

Indexed keywords

CALCIUM; DEFEROXAMINE MESYLATE; ESTRADIOL; FERRITIN; FOLIC ACID; FOLLITROPIN; GLUCOSE; GONADORELIN AGONIST; GONADOTROPIN; LUTEINIZING HORMONE; PARATHYROID HORMONE; PHOSPHATE; TESTOSTERONE; THYROID HORMONE;

ADOLESCENT; ADULT; AMENORRHEA; ANTHROPOMETRIC PARAMETERS; ARTICLE; AUDIOMETRY; BETA THALASSEMIA; BODY HEIGHT; BODY MASS; BODY WEIGHT; CALCIUM BLOOD LEVEL; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DELAYED PUBERTY; ECHOCARDIOGRAPHY; EGYPT; ERYTHROCYTE TRANSFUSION; ESTRADIOL BLOOD LEVEL; FEMALE; FERRITIN BLOOD LEVEL; FOLLITROPIN BLOOD LEVEL; GLUCOSE BLOOD LEVEL; GONADOTROPIN BLOOD LEVEL; HUMAN; HYPOGONADOTROPIC HYPOGONADISM; LIVER FUNCTION TEST; LUTEINIZING HORMONE BLOOD LEVEL; MALE; MENSTRUAL IRREGULARITY; OLIGOMENORRHEA; OPHTHALMOSCOPY; PARATHYROID HORMONE BLOOD LEVEL; PATIENT COMPLIANCE; PHOSPHATE BLOOD LEVEL; PREVALENCE; PRIORITY JOURNAL; RISK FACTOR; SCHOOL CHILD; SECONDARY AMENORRHEA; SEX DIFFERENCE; TESTOSTERONE BLOOD LEVEL; THYROID HORMONE BLOOD LEVEL;

ADOLESCENT; ADULT; BETA-THALASSEMIA; CASE-CONTROL STUDIES; CHILD; CHILD DEVELOPMENT; CROSS-SECTIONAL STUDIES; EGYPT; FEMALE; FERRITINS; GONADOTROPINS; GROWTH; HUMANS; IRAN; MALE; PUBERTY, DELAYED; RISK FACTORS;

EID: 34748860388     PISSN: 10245332     EISSN: 16078454     Source Type: Journal    
DOI: 10.1080/10245330701448503     Document Type: Article

References (50)

1. Cooley, TB and Lee, P. (1925) A series of cases of splenomegaly in children with anemia and peculiar changes. Trans Am Pediatr Soc, 37, pp. 29-30.
2. Saka, N., Sukur, M., Bundak, R., Anak, S., Neyzi, O. and Gedikoglu, G. (1995) Growth and puberty in thalassemia major. J Pediatr Endocrinol Metab, 8, pp. 181-186.
3. Jensen, CE, Tuck, SM, Agnew, JE, Koneru, S., Morris, RW, Morris, RW, Yardumian, A., Prescott, E., Hoffbrand, AV and Wonke, B. (1998) High prevalence of low bone mass in thalassaemia major. Br J Haemat, 103, pp. 911-915.
4. Vullo, C., De Sanctis, V., Katz, M., Wonke, B., Hoffbrand, AV, Bagni, B., Torresani, T., Tolis, G., Masiero, M., Palma, A Di and Borgatti, L. (1990) Endocrine abnormalities in thalassemia. Ann NY Acad Sci, 612, pp. 293-310.
5. Skordis, N., Michaelidou, M., Savva, SC, Ioannou, Y., Rousounides, A., Kleanthous, M., Skordos, G. and Christou, S. (2006) The impact of genotype on endocrine complications in thalassaemia major. Eur J Haematol, 77, pp. 150-156.
6. Berkovitch, M., Bistritzer, T., Milone, S., Periman, K., Kucharczk, W., Koren, G. and Olivieri, NF (2000) Iron deposition in the anterior pituitary in homozygous beta-thalassaemia: MRI evaluation and correlation with gonadal function. J Pediatr Endocrinol Metab, 13, pp. 179-184.
7. Miskin, H., Yaniv, I., Berant, M., Hershko, C. and Tamary, H. (2003) Reversal of cardiac complications in thalassemia major by long-term intermittent daily intensive iron chelation. Eur J Haematol, 70, pp. 398-403.
8. Roth, C., Pekrun, A., Bartz, M., Jarry, H., Eber, S., Lakomek, M. and Schroter, W. (1997) Short stature and failure of pubertal development in thalassaemia major; evidence for hypothalamic neurosecretory dysfunction of growth hormone secretion and defective pituitary gonadotropin secretion. Eur J Pediatr, 156, pp. 777-783.
9. De Sanctis, V. (2002) Growth and puberty and its management in thalassemia. Horm Res, 58, pp. 72-79.
10. Oerter, KE, Kamp, GA, Munson, PJ, Nienhuis, AW, Cassorla, FG and Manasco, PK (1993) Multiple hormone deficiencies in children with hemochromatosis. J Clin Endocrinol Metab, 76, pp. 357-361.
11. Bronspiegel-Weintrob, N., Oliveri, NF, Tyler, B., Andrews, DF, Freedman, MH and Holland, FJ (1990) Effect of age at the start of iron chelation therapy on gonadal function in β-thalassemia major. N Engl J Med, 323, pp. 713-719.
12. De Sanctis, V., Katz, M., Vullo, C., Bagni, B., Ughi, M. and Wonke, B. (1994) Effect of different treatment regimes of linear growth and final height in beta thalassemia major. Clin Endocrinol, 40, pp. 791-798.
13. Soliman, AT, Nasr, I., Thabet, A., Rizk, MM and Matary, W El (2005) Human chorionic gonadotropin therapy in adolescent boys with constitutional delayed puberty vs. those with β-thalassemia major. Metabolism, 54, pp. 15-23.
14. Soliman, AT, Elzalabany, MM, Ragab, M., Fattah, M Abdel, Hassab, H., Rogol, AD and Ansari, BM (2000) Spontaneous and GnRH-provoked gonadotropin secretion and testosterone response to human chorionic gonadotropin in adolescent boys with thalassaemia major and delayed puberty. J Trop Pediatr, 46:2, pp. 79-85.
15. Soliman, AT, Elzalabany, M., Amer, M. and Ansari, BM (1999) Growth and pubertal development in transfusion dependent children and adolescents with thalassemia major and sickle cell disease: A comparative study. J Trop Pediatr, 45, pp. 23-30.
16. Salama, OS, AL-Tonbary, YA, Shahin, RA and Eldeen, OA Sharaf (2006) Unbalanced bone turnover in children with β-thalassemia. Hematology, 11:3, pp. 197-202.
17. Tanner, JM and Whithehouse, RH (1976) Clinical longitudinal standards for height, weight, height velocity, weight velocity, and the stages of puberty. Arch Dis Child, 51, pp. 170-179.
18. Kuczmarski, RJ, Ogden, CL and Grummer-Strawn, LM (2000) CDC growth charts: United States advance data from vital and health statistics, National Center for Health Statistics, Hyattsville, MD
19. Tanner, JM (1973) Growth at adolescence, p. 32. Oxford Blackwell Science, Oxford
20. Evered, DC, Ormston, BJ, Smith, PA, Hall, R. and Bird, T. (1973) Grade of hypothyroidism. BMJ, 1, pp. 657-662.
21. SPSS (1999) Statistical package for social science. Standard version 10.0, SPSS Inc., Chicago, IL
22. Moayeri, H. and Oloomi, Z. (2006) Prevalence of growth and puberty failure with respect to growth hormone and gonadotropins secretion in beta-thalassemia major. Arch Iran Med, 9:4, pp. 329-334.
23. Gulati, R., Bhatia, V. and Agarwal, SS (2000) Early onset of endocrine abnormalities in beta-thalassemia major in a developing country. J Pediatr Endocrinol Metab, 13, pp. 651-656.
24. Pignatti, CB, De Stefano, P. and Zonta, L. (1985) Growth and sexual maturation in thalassemia major. J Pediatr, 106, pp. 150-155.
25. Anthi, A Protonotariou and George, J Tolis (2000) Rreproductive health in female patients with B-thalassaemia major. Ann NY Acad Sci, 900, pp. 119-124.
26. De Sanctis, V., Vullo, C., Katz, M., Wonke, B., Hoffbrand, AV and Bagni, B. (1988) Hypothalamic-pituitary-gonadal axis in thalassaemic patients with secondary amenorrhea. Obstet Gynecol, 72, pp. 643-647.
27. Chatterjee, R., Katz, M., Cox, TF and Porter, JB (1993) Prospective study of the hypothalamic-pituitary axis in thalassaemic patients who developed secondary amenorrhea. Clin Endocrinol, 39, pp. 287-296.
28. Raiola, G., Galati, MC and De-Sanctis, V. (2003) Growth and puberty in thalassemia major. J Pediat Endocrinol Metab, 16, pp. 259-266.
29. Italian Working Group on Endocrine Complications in Non-Endocrine. Diseases (1995) Multicentre study on prevalence of endocrine complications in thalassaemia major. Clin Endocrinol, 42, pp. 581-586.
30. Costin, G., Kogut, M., Hyman, CB and Ortega, J. (1979) Endocrine abnormalities in thalassemia major. Am J Dis Child, 133, pp. 497-502.
31. Suda, K. (1985) Hemosiderin deposition in the pancreas. Arch Pathol Lab Med, 109, pp. 996-999.
32. Masala, A., Meloni, T., Gallisai, D., Alagna, S., Rovasio, PP, Rassu, S. and Milia, AF (1984) Endocrine functioning in multitransfused prepubertal patients with homozygous beta thalassemia. J Clin Enocrinol Metab, 58, pp. 667-670.
33. Zervas, A., Katopodi, A., Protonotariou, A., Livadas, S., Karagiorga, M., Politis, C. and Tolis, G. (2002) Assessment of thyroid function in two hundred patients with beta-thalassemia major. Thyoid, 12, pp. 151-154.
34. Olivieri, NF, Nathan, DG and Macmillan, JH (1994) Survival in medically treated patients with homozygous β-thalassemia. NEJM, 331, pp. 574-578.
35. Grundy, RG, Woods, KA, Savage, MO and Evans, JPM (1994) Relationship of endocrinopathy to iron chelation status in young patients with thalassemia major. Arch Dis Child, 71, pp. 128-132.
36. Danesi, L., Scacchi, M., De Martin, M., Dubini, A., Massaro, P., Majolo, AT, Cavagnini, F. and Polli, EE (1992) Evaluation of hypothalamic-pituitary function in patients with thalassemia major. Endocrinol Invest, 15:3, pp. 177-184.
37. Sparacia, G., Iaia, A., Banco, A., D'Angelo, P. and Lagalla, R. (2000) Transfusional hemochromatosis: Quantitative relation of MR imaging pituitary signal intensity reduction to hypogonadotropic hypogonadism. Radiology, 215, pp. 818-823.
38. Tuck, SM, Jensen, CE, Wonke, B. and Yardumian, A. (1998) Pregnancy management and outcomes in women with thalassaemia major. J Pediatr Endocrinol Metab, 11, pp. 923-928.
39. Tiosano, D. and Hochberg, Z. (2001) Endocrine complications of thalassaemia. J Endocrinol Invest, 24, pp. 716-723.
40. Mohammadian, S., Bazrafshan, RH and Sadeghi-Najad, A. (2003) Endocrine gland abnormalities in thalassaemia major: A brief review. J Pediatr Endocrinol Metab, 16, pp. 957-964.
41. Chatterjee, R. and Katz, M. (2000) Reversible hypogonadotrophic hypogonadism in sexually infantile male thalassaemic patients with transfusional iron overload. Clin Endocrinol, 53:33, p. 42.
42. Papadimas, J., Mandala, E., Pados, G., Kokkas, B., Georgiadis, G. and Terlatzis, B. (1996) Pituitary-testicular axis in men with beta-thalassaemia major. Hum Reprod, 11, pp. 1900-1904.
43. Kiess, W., Reich, A., Meyer, K., Glasow, A., Deutscher, J., Klammt, J., Yang, Y., Muller, G. and Kratzsch, J. (1999) A role for leptin in sexual maturation and puberty?. Horm Res, 51, pp. 55-63.
44. Teirmaa, T., Luukkaa, V., Rourou, J., Koulu, M. and Huupponen, R. (1998) Correlation between circulating leptin and LH during the menstrual cycle in normal-weight women. Eur J Endocrinol, 139, pp. 190-194.
45. Perrone, L., Perrotta, S., Raimondo, P., Mucerino, J., De Rosa, C., Siciliani, MC, Santoro, N. and Giudice, EM Del (2003) Inappropriate leptin secretion in thalassaemia: A potential cofactor of pubertal timing derangement. J Pediatr Endocrinol Metab, 16, pp. 877-881.
46. Karachaliou, F., Vlachopapadopoulou, E., Theochari, M., Konstandellou, E. and Michalados, S. (2006) Leptin levels in patients with thalassemia major. Minerva Pediatr, 58:4, pp. 373-378.
47. Dedousis, GVZ, Kyrtsonis, MC, Andrikopoulos, NE, Voskaridou, E. and Loutradis, A. (2002) Inverse correlation of plasma leptin and soluble transferrin receptor levels in β-thalassaemia patients. Ann Hematol, 81, pp. 543-547.
48. Weintraub, LR, Goral, A. and Grasso, J. (1988) Collagen biosynthesis in iron overload. Ann NY Acad Sci, 526, pp. 179-184.
49. Skordis, N., Michaelidou, M., Savva, SC, Ioannou, Y., Rousounides, A., Kleanthous, M., Skordos, G. and Christou, S. (2006) The impact of genotype on endocrine complications in thalassaemia major. Eur J Haematol, 77:2, pp. 150-156.
50. Shalitin, S., Carmi, D., Weintrob, N., Phillip, M., Miskin, H., Kornreich, L., Zilber, R., Yaniv, I. and Tamary, H. (2005) Serum ferritin level as a predictor of impaired growth and puberty in thalassemia major patients. Eur J Haematol, 74, pp. 93-100.