-
1
-
-
0025241769
-
Curability of tumors bearing herpes thymidine kinase genes transferred by retroviral vectors
-
Moolten FL, Wells JM: Curability of tumors bearing herpes thymidine kinase genes transferred by retroviral vectors. J Natl Cancer Inst 82:297-300, 1990
-
(1990)
J Natl Cancer Inst
, vol.82
, pp. 297-300
-
-
Moolten, F.L.1
Wells, J.M.2
-
2
-
-
0025899005
-
Selective killing of glioma cells in culture and in vivo by retrovirus transfer of the herpes simplex virus thymidine kinase gene
-
Ezzeddine ZD, Martuza RL, Platika D, et al: Selective killing of glioma cells in culture and in vivo by retrovirus transfer of the herpes simplex virus thymidine kinase gene. New Biol 3:608-614, 1991
-
(1991)
New Biol
, vol.3
, pp. 608-614
-
-
Ezzeddine, Z.D.1
Martuza, R.L.2
Platika, D.3
-
3
-
-
0034242458
-
Effective treatment of experimental glioblastoma by HSV vector-mediated TNF alpha and HSV-tk gene transfer in combination with radiosurgery and ganciclovir administration
-
Niranjan A, Moriuchi S, Lunsford LD, et al: Effective treatment of experimental glioblastoma by HSV vector-mediated TNF alpha and HSV-tk gene transfer in combination with radiosurgery and ganciclovir administration. Mol Ther 2:114-120, 2000
-
(2000)
Mol Ther
, vol.2
, pp. 114-120
-
-
Niranjan, A.1
Moriuchi, S.2
Lunsford, L.D.3
-
4
-
-
0033800317
-
HSV vector cytotoxicity is inversely correlated with effective TK/GCV suicide gene therapy of rat gliosarcoma
-
Moriuchi S, Krisky DM, Marconi PC, et al: HSV vector cytotoxicity is inversely correlated with effective TK/GCV suicide gene therapy of rat gliosarcoma. Gene Ther 7:1483-1490, 2000
-
(2000)
Gene Ther
, vol.7
, pp. 1483-1490
-
-
Moriuchi, S.1
Krisky, D.M.2
Marconi, P.C.3
-
5
-
-
0028805459
-
Selective enhancement of radiation response of herpes simplex virus thymidine kinase transduced 9L gliosarcoma cells in vitro and in vivo by antiviral agents
-
Kim JH, Kim SH, Kolozsvary A, et al: Selective enhancement of radiation response of herpes simplex virus thymidine kinase transduced 9L gliosarcoma cells in vitro and in vivo by antiviral agents. Int J Radiat Oncol Biol Phys 33:861-868, 1995
-
(1995)
Int J Radiat Oncol Biol Phys
, vol.33
, pp. 861-868
-
-
Kim, J.H.1
Kim, S.H.2
Kolozsvary, A.3
-
6
-
-
0028032719
-
Selective enhancement by an antiviral agent of the radiation-induced cell killing of human glioma cells transduced with HSV-tk gene
-
Kim JH, Kim SH, Brown SL, et al: Selective enhancement by an antiviral agent of the radiation-induced cell killing of human glioma cells transduced with HSV-tk gene. Cancer Res 54:6053-6056, 1994
-
(1994)
Cancer Res
, vol.54
, pp. 6053-6056
-
-
Kim, J.H.1
Kim, S.H.2
Brown, S.L.3
-
7
-
-
12144287935
-
Phase I-II trial evaluating combined intensity-modulated radiotherapy and in situ gene therapy with or without hormonal therapy in treatment of prostate cancer-interim report on PSA response and biopsy data
-
Teh BS, Ayala G, Aguilar L, et al: Phase I-II trial evaluating combined intensity-modulated radiotherapy and in situ gene therapy with or without hormonal therapy in treatment of prostate cancer-interim report on PSA response and biopsy data. Int J Radiat Oncol Biol Phys 58:1520-1529, 2004
-
(2004)
Int J Radiat Oncol Biol Phys
, vol.58
, pp. 1520-1529
-
-
Teh, B.S.1
Ayala, G.2
Aguilar, L.3
-
8
-
-
0034086627
-
Fractionated radiation therapy in combination with adenoviral delivery of the cytosine deaminase gene and 5-fluorocytosine enhances cytotoxic and antitumor effects in human colorectal and cholangiocarcinoma models
-
Stackhouse MA, Pederson LC, Grizzle WE, et al: Fractionated radiation therapy in combination with adenoviral delivery of the cytosine deaminase gene and 5-fluorocytosine enhances cytotoxic and antitumor effects in human colorectal and cholangiocarcinoma models. Gene Ther 7:1019-1026, 2000
-
(2000)
Gene Ther
, vol.7
, pp. 1019-1026
-
-
Stackhouse, M.A.1
Pederson, L.C.2
Grizzle, W.E.3
-
9
-
-
0030817590
-
Molecular chemotherapy combined with radiation therapy enhances killing of cholangiocarcinoma cells in vitro and in vivo
-
Pederson LC, Buchsbaum DJ, Vickers SM, et al: Molecular chemotherapy combined with radiation therapy enhances killing of cholangiocarcinoma cells in vitro and in vivo. Cancer Res 57:4325-4332, 1997
-
(1997)
Cancer Res
, vol.57
, pp. 4325-4332
-
-
Pederson, L.C.1
Buchsbaum, D.J.2
Vickers, S.M.3
-
10
-
-
0030666029
-
Pronounced antitumor effects and tumor radiosensitization of double suicide gene therapy
-
Rogulski KR, Zhang K, Kolozsvary A, et al: Pronounced antitumor effects and tumor radiosensitization of double suicide gene therapy. Clin Cancer Res 3:2081-2088, 1997
-
(1997)
Clin Cancer Res
, vol.3
, pp. 2081-2088
-
-
Rogulski, K.R.1
Zhang, K.2
Kolozsvary, A.3
-
11
-
-
10744227813
-
Phase I study of replication-competent adenovirus-mediated double-suicide gene therapy in combination with conventional-dose three-dimensional conformai radiation therapy for the treatment of newly diagnosed, intermediate- to high-risk prostate cancer
-
Freytag SO, Strieker H, Pegg J, et al: Phase I study of replication-competent adenovirus-mediated double-suicide gene therapy in combination with conventional-dose three-dimensional conformai radiation therapy for the treatment of newly diagnosed, intermediate- to high-risk prostate cancer. Cancer Res 63:7497-7506, 2003
-
(2003)
Cancer Res
, vol.63
, pp. 7497-7506
-
-
Freytag, S.O.1
Strieker, H.2
Pegg, J.3
-
12
-
-
0029148876
-
Stereotactic injection of herpes simplex thymidine kinase vector producer cells (PA317-G1Tk1SvNa. 7) and intravenous ganciclovir for the treatment of progressive or recurrent primary supratentorial pediatric malignant brain tumors
-
Kun LE, Gajjar A, Muhlbauer M, et al: Stereotactic injection of herpes simplex thymidine kinase vector producer cells (PA317-G1Tk1SvNa. 7) and intravenous ganciclovir for the treatment of progressive or recurrent primary supratentorial pediatric malignant brain tumors. Hum Gene Ther 6:1231-1255, 1995
-
(1995)
Hum Gene Ther
, vol.6
, pp. 1231-1255
-
-
Kun, L.E.1
Gajjar, A.2
Muhlbauer, M.3
-
13
-
-
0034694011
-
A phase III clinical evaluation of herpes simplex virus type 1 thymidine kinase and ganciclovir gene therapy as an adjuvant to surgical resection and radiation in adults with previously untreated glioblastoma multiforme
-
Rainov NG: A phase III clinical evaluation of herpes simplex virus type 1 thymidine kinase and ganciclovir gene therapy as an adjuvant to surgical resection and radiation in adults with previously untreated glioblastoma multiforme. Hum Gene Ther 11:2389-2401, 2000
-
(2000)
Hum Gene Ther
, vol.11
, pp. 2389-2401
-
-
Rainov, N.G.1
-
14
-
-
0032553648
-
The treatment of malignant mesothelioma with a gene modified cancer cell line: A phase I study
-
Schwarzenberger P, Harrison L, Weinacker A, et al: The treatment of malignant mesothelioma with a gene modified cancer cell line: A phase I study. Hum Gene Ther 9:2641-2649, 1998
-
(1998)
Hum Gene Ther
, vol.9
, pp. 2641-2649
-
-
Schwarzenberger, P.1
Harrison, L.2
Weinacker, A.3
-
15
-
-
0032037139
-
Gene therapy for malignant mesothelioma: A novel approach for an incurable cancer with increased incidence in Louisiana
-
Schwarzenberger P, Harrison L, Weinacker A, et al: Gene therapy for malignant mesothelioma: A novel approach for an incurable cancer with increased incidence in Louisiana. J La State Med Soc 150:168-174, 1998
-
(1998)
J La State Med Soc
, vol.150
, pp. 168-174
-
-
Schwarzenberger, P.1
Harrison, L.2
Weinacker, A.3
-
16
-
-
19244362665
-
Treatment of advanced CNS malignancies with the recombinant adenovirus H5.010RSVTK: A phase I trial
-
Eck SL, Alavi JB, Alavi A, et al: Treatment of advanced CNS malignancies with the recombinant adenovirus H5.010RSVTK: A phase I trial. Hum Gene Ther 7:1465-1482, 1996
-
(1996)
Hum Gene Ther
, vol.7
, pp. 1465-1482
-
-
Eck, S.L.1
Alavi, J.B.2
Alavi, A.3
-
17
-
-
2442767029
-
A phase I/II study of herpes simplex virus type 1 thymidine kinase "suicide" gene therapy for recurrent glioblastoma: Study Group on Gene Therapy for Glioblastoma
-
Klatzmann D, Valery CA, Bensimon G, et al: A phase I/II study of herpes simplex virus type 1 thymidine kinase "suicide" gene therapy for recurrent glioblastoma: Study Group on Gene Therapy for Glioblastoma. Hum Gene Ther 9:2595-2604, 1998
-
(1998)
Hum Gene Ther
, vol.9
, pp. 2595-2604
-
-
Klatzmann, D.1
Valery, C.A.2
Bensimon, G.3
-
18
-
-
2442721450
-
A phase I/II dose-escalation study of herpes simplex virus type 1 thymidine kinase "suicide" gene therapy for metastatic melanoma: Study Group on Gene Therapy of Metastatic Melanoma
-
Klatzmann D, Cherin P, Bensimon G, et al: A phase I/II dose-escalation study of herpes simplex virus type 1 thymidine kinase "suicide" gene therapy for metastatic melanoma: Study Group on Gene Therapy of Metastatic Melanoma. Hum Gene Ther 9:2585-2594, 1998
-
(1998)
Hum Gene Ther
, vol.9
, pp. 2585-2594
-
-
Klatzmann, D.1
Cherin, P.2
Bensimon, G.3
-
19
-
-
0031463632
-
Therapy of malignant brain tumors by intratumoral implantation of retroviral vector-producing cells
-
Ram Z, Culver KW, Oshiro EM, et al: Therapy of malignant brain tumors by intratumoral implantation of retroviral vector-producing cells. Nat Med 3:1354-1361, 1997
-
(1997)
Nat Med
, vol.3
, pp. 1354-1361
-
-
Ram, Z.1
Culver, K.W.2
Oshiro, E.M.3
-
20
-
-
0025294971
-
Ionizing radiation regulates expression of the c-jun protooncogene
-
Sherman ML, Datta R, Hallahan DE, et al: Ionizing radiation regulates expression of the c-jun protooncogene. Proc Natl Acad Sci U S A 87:5663-5666, 1990
-
(1990)
Proc Natl Acad Sci U S A
, vol.87
, pp. 5663-5666
-
-
Sherman, M.L.1
Datta, R.2
Hallahan, D.E.3
-
21
-
-
0025919744
-
Mechanisms of X-ray-mediated protooncogene c-jun expression in radiation-induced human sarcoma cell lines
-
Hallahan DE, Virudachalam S, Beckett M, et al: Mechanisms of X-ray-mediated protooncogene c-jun expression in radiation-induced human sarcoma cell lines. Int J Radiat Oncol Biol Phys 21: 1677-1681, 1991
-
(1991)
Int J Radiat Oncol Biol Phys
, vol.21
, pp. 1677-1681
-
-
Hallahan, D.E.1
Virudachalam, S.2
Beckett, M.3
-
22
-
-
0026078126
-
Protein kinase C mediates x-ray inducibility of nuclear signal transducers EGR1 and JUN
-
Hallahan DE, Sukhatme VP, Sherman ML, et al: Protein kinase C mediates x-ray inducibility of nuclear signal transducers EGR1 and JUN. Proc Natl Acad Sci U S A 88:2156-2160, 1991
-
(1991)
Proc Natl Acad Sci U S A
, vol.88
, pp. 2156-2160
-
-
Hallahan, D.E.1
Sukhatme, V.P.2
Sherman, M.L.3
-
23
-
-
0026452858
-
Ionizing radiation activates transcription of the EGRI gene via CArG elements
-
Datta R, Rubin E, Sukhatme V, et al: Ionizing radiation activates transcription of the EGRI gene via CArG elements. Proc Natl Acad Sci U S A 89:10149-10153, 1992
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 10149-10153
-
-
Datta, R.1
Rubin, E.2
Sukhatme, V.3
-
24
-
-
0027512020
-
Reactive oxygen intermediates target CC(A/T)6GG sequences to mediate activation of the early growth response 1 transcription factor gene by ionizing radiation
-
Datta R, Taneja N, Sukhatme VP, et al: Reactive oxygen intermediates target CC(A/T)6GG sequences to mediate activation of the early growth response 1 transcription factor gene by ionizing radiation. Proc Natl Acad Sci U S A 90:2419-2422, 1993
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 2419-2422
-
-
Datta, R.1
Taneja, N.2
Sukhatme, V.P.3
-
25
-
-
0022369998
-
Tumor necrosis factor (TNF)
-
Old LJ: Tumor necrosis factor (TNF). Science 230:630-632, 1985
-
(1985)
Science
, vol.230
, pp. 630-632
-
-
Old, L.J.1
-
26
-
-
0000546442
-
Phase I dose-escalation study of tumor necrosis factor-alpha and concomitant radiation therapy
-
Hallahan DE, Vokes EE, Rubin SJ, et al: Phase I dose-escalation study of tumor necrosis factor-alpha and concomitant radiation therapy. Cancer J Sci Am 1:204-209, 1995
-
(1995)
Cancer J Sci Am
, vol.1
, pp. 204-209
-
-
Hallahan, D.E.1
Vokes, E.E.2
Rubin, S.J.3
-
27
-
-
0029159918
-
Spatial and temporal control of gene therapy using ionizing radiation
-
Hallahan DE, Mauceri HJ, Seung LP, et al: Spatial and temporal control of gene therapy using ionizing radiation. Nat Med 1:786-791, 1995
-
(1995)
Nat Med
, vol.1
, pp. 786-791
-
-
Hallahan, D.E.1
Mauceri, H.J.2
Seung, L.P.3
-
28
-
-
0030669334
-
Increased injection number enhances adenoviral genetic radiotherapy
-
Mauceri HJ, Seung LP, Grdina WL, et al: Increased injection number enhances adenoviral genetic radiotherapy. Radiat Oncol Investig 5:220-226, 1997
-
(1997)
Radiat Oncol Investig
, vol.5
, pp. 220-226
-
-
Mauceri, H.J.1
Seung, L.P.2
Grdina, W.L.3
-
29
-
-
0031951530
-
Adenoviral TNF-alpha gene therapy and radiation damage tumor vasculature in a human malignant glioma xenograft
-
Staba MJ, Mauceri HJ, Kufe DW, et al: Adenoviral TNF-alpha gene therapy and radiation damage tumor vasculature in a human malignant glioma xenograft. Gene Ther 5:293-300, 1998
-
(1998)
Gene Ther
, vol.5
, pp. 293-300
-
-
Staba, M.J.1
Mauceri, H.J.2
Kufe, D.W.3
-
30
-
-
0032199393
-
Tumor necrosis factor-alpha-based gene therapy enhances radiation cytotoxicity in human prostate cancer
-
Chung TD, Mauceri HJ, Hallahan DE, et al: Tumor necrosis factor-alpha-based gene therapy enhances radiation cytotoxicity in human prostate cancer. Cancer Gene Ther 5:344-349, 1998
-
(1998)
Cancer Gene Ther
, vol.5
, pp. 344-349
-
-
Chung, T.D.1
Mauceri, H.J.2
Hallahan, D.E.3
-
31
-
-
0034926709
-
Clinical protocol. An open-label, phase I, dose-escalation study of tumor necrosis factor-alpha (TNFerade Biologic) gene transfer with radiation therapy for locally advanced, recurrent, or metastatic solid tumors
-
Sharma A, Mani S, Hanna N, et al: Clinical protocol. An open-label, phase I, dose-escalation study of tumor necrosis factor-alpha (TNFerade Biologic) gene transfer with radiation therapy for locally advanced, recurrent, or metastatic solid tumors. Hum Gene Ther 12:1109-1131, 2001
-
(2001)
Hum Gene Ther
, vol.12
, pp. 1109-1131
-
-
Sharma, A.1
Mani, S.2
Hanna, N.3
-
32
-
-
34848886229
-
Phase I dose escalation study of tumor necrosis factor-alpha. Gene transfer with radiation therapy for advanced solid tumors
-
abstr 187
-
Sharma AKH, Nemunaitis J, Posner M, et al: Phase I dose escalation study of tumor necrosis factor-alpha. Gene transfer with radiation therapy for advanced solid tumors. Proc Am Soc Ther Radiat Oncol, 2001 (abstr 187)
-
(2001)
Proc Am Soc Ther Radiat Oncol
-
-
Sharma, A.K.H.1
Nemunaitis, J.2
Posner, M.3
-
33
-
-
0011322512
-
A phase I study of human necrosis factor-alpha gene transfer with radiation therapy for advanced solid tumors
-
abstr 344
-
Hanna NN, Nemunaitis J, Cunningham CC, et al: A phase I study of human necrosis factor-alpha gene transfer with radiation therapy for advanced solid tumors. Proc Am Soc Clin Oncol 21:87a, 2002 (abstr 344)
-
(2002)
Proc Am Soc Clin Oncol
, vol.21
-
-
Hanna, N.N.1
Nemunaitis, J.2
Cunningham, C.C.3
-
34
-
-
34848891080
-
Safety and efficacy of TNFerade in unresectable, locally advanced pancreatic cancer)LAPC): Results of the first three cohorts of a dose-escalating study
-
Presented at the, June 5-8, New Orleans, LA
-
Senzer N, Chung T, Hecht JR, et al: Safety and efficacy of TNFerade in unresectable, locally advanced pancreatic cancer)LAPC): Results of the first three cohorts of a dose-escalating study. Presented at the 40th Annual Meeting of the American Society of Clinical Oncology, June 5-8, 2004, New Orleans, LA
-
(2004)
40th Annual Meeting of the American Society of Clinical Oncology
-
-
Senzer, N.1
Chung, T.2
Hecht, J.R.3
-
35
-
-
84882846561
-
Long-term outcome in esophageal cancer after endoscopically delivered intratumoral (IT) injections of TNFerade with neoadjuvant chemoradiotherapy (CRT), 2006
-
Presented at the, January 26-28, San Francisco, CA
-
Senzer N, Reid T, Mauer A, et al: Long-term outcome in esophageal cancer after endoscopically delivered intratumoral (IT) injections of TNFerade with neoadjuvant chemoradiotherapy (CRT), 2006. Presented at the Gastrointestinal Cancers Symposium, January 26-28, 2006, San Francisco, CA
-
(2006)
Gastrointestinal Cancers Symposium
-
-
Senzer, N.1
Reid, T.2
Mauer, A.3
-
36
-
-
33748864226
-
The PACT trial: Interim results of a randomized trial of TNFerade biologic plus chemoradiation (CRT) compared to CRT alone in locally advanced pancreatic cancer (LAPC)
-
suppl; abstr 4102, 203s
-
Senzer N, Javle M, Reid T, et al: The PACT trial: Interim results of a randomized trial of TNFerade biologic plus chemoradiation (CRT) compared to CRT alone in locally advanced pancreatic cancer (LAPC). J Clin Oncol 24:203s, 2006 (suppl; abstr 4102)
-
(2006)
J Clin Oncol
, vol.24
-
-
Senzer, N.1
Javle, M.2
Reid, T.3
-
37
-
-
0025864440
-
Experimental therapy of human glioma by means of a genetically engineered virus mutant
-
Martuza RL, Malick A, Marken JM, et al: Experimental therapy of human glioma by means of a genetically engineered virus mutant. Science 252: 854-856, 1991
-
(1991)
Science
, vol.252
, pp. 854-856
-
-
Martuza, R.L.1
Malick, A.2
Marken, J.M.3
-
38
-
-
0025688373
-
Mapping of herpes simplex virus-1 neurovirulence to gamma 134.5, a gene nonessential for growth in culture
-
Chou J, Kern ER, Whitley RJ, et al: Mapping of herpes simplex virus-1 neurovirulence to gamma 134.5, a gene nonessential for growth in culture. Science 250:1262-1266, 1990
-
(1990)
Science
, vol.250
, pp. 1262-1266
-
-
Chou, J.1
Kern, E.R.2
Whitley, R.J.3
-
39
-
-
0029023868
-
Attenuated multi-mutated herpes simplex virus-1 for the treatment of malignant gliomas
-
Mineta T, Rabkin SD, Yazaki T, et al: Attenuated multi-mutated herpes simplex virus-1 for the treatment of malignant gliomas. Nat Med 1:938943, 1995
-
(1995)
Nat Med
, vol.1
, pp. 938943
-
-
Mineta, T.1
Rabkin, S.D.2
Yazaki, T.3
-
40
-
-
0025280142
-
In vivo behavior of genetically engineered herpes simplex viruses R7017 and R7020. II. Studies in immunocompetent and immunosuppressed owl monkeys (Aotus trivirgatus)
-
Meignier B, Martin B, Whitley RJ, et al: In vivo behavior of genetically engineered herpes simplex viruses R7017 and R7020. II. Studies in immunocompetent and immunosuppressed owl monkeys (Aotus trivirgatus). J Infect Dis 162:313-321, 1990
-
(1990)
J Infect Dis
, vol.162
, pp. 313-321
-
-
Meignier, B.1
Martin, B.2
Whitley, R.J.3
-
41
-
-
12944315014
-
Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: Results of a phase I trial
-
Markert JM, Medlock MD, Rabkin SD, et al: Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: Results of a phase I trial. Gene Ther 7:867-874, 2000
-
(2000)
Gene Ther
, vol.7
, pp. 867-874
-
-
Markert, J.M.1
Medlock, M.D.2
Rabkin, S.D.3
-
42
-
-
12944272092
-
Toxicity evaluation of replication-competent herpes simplex virus (ICP 34.5 null mutant 1716) in patients with recurrent malignant glioma
-
Rampling R, Cruickshank G, Papanastassiou V, et al: Toxicity evaluation of replication-competent herpes simplex virus (ICP 34.5 null mutant 1716) in patients with recurrent malignant glioma. Gene Ther 7:859-866, 2000
-
(2000)
Gene Ther
, vol.7
, pp. 859-866
-
-
Rampling, R.1
Cruickshank, G.2
Papanastassiou, V.3
-
44
-
-
0031909185
-
Enhancement of replication of genetically engineered herpes simplex viruses by ionizing radiation: A new paradigm for destruction of therapeutically intractable tumors
-
Advani SJ, Sibley GS, Song PY, et al: Enhancement of replication of genetically engineered herpes simplex viruses by ionizing radiation: A new paradigm for destruction of therapeutically intractable tumors. Gene Ther 5:160-165, 1998
-
(1998)
Gene Ther
, vol.5
, pp. 160-165
-
-
Advani, S.J.1
Sibley, G.S.2
Song, P.Y.3
-
45
-
-
33845731246
-
Phase I, open-label, dose-escalating study of a genetically engineered herpes simplex virus, NV1020, in subjects with metastatic colorectal carcinoma to the liver
-
Kemeny N, Brown K, Covey A, et al: Phase I, open-label, dose-escalating study of a genetically engineered herpes simplex virus, NV1020, in subjects with metastatic colorectal carcinoma to the liver. Hum Gene Ther 17:1214-1224, 2006
-
(2006)
Hum Gene Ther
, vol.17
, pp. 1214-1224
-
-
Kemeny, N.1
Brown, K.2
Covey, A.3
-
46
-
-
0344188096
-
An adenovirus mutant that replicates selectively in p53-deficient human tumor cells
-
Bischoff JR, Kirn DH, Williams A, et al: An adenovirus mutant that replicates selectively in p53-deficient human tumor cells. Science 274:373-376, 1996
-
(1996)
Science
, vol.274
, pp. 373-376
-
-
Bischoff, J.R.1
Kirn, D.H.2
Williams, A.3
-
47
-
-
0033831080
-
A controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer
-
Khuri FR, Nemunaitis J, Ganly I, et al: A controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer. Nat Med 6:879-885, 2000
-
(2000)
Nat Med
, vol.6
, pp. 879-885
-
-
Khuri, F.R.1
Nemunaitis, J.2
Ganly, I.3
-
48
-
-
0033693231
-
Selective replication and oncolysis in p53 mutant tumors with ONYX-015, an E1B-55kD gene-deleted adenovirus, in patients with advanced head and neck cancer: A phase II trial
-
Nemunaitis J, Ganly I, Khuri F, et al: Selective replication and oncolysis in p53 mutant tumors with ONYX-015, an E1B-55kD gene-deleted adenovirus, in patients with advanced head and neck cancer: A phase II trial. Cancer Res 60:6359-6366, 2000
-
(2000)
Cancer Res
, vol.60
, pp. 6359-6366
-
-
Nemunaitis, J.1
Ganly, I.2
Khuri, F.3
-
49
-
-
0035863458
-
Phase II trial of intratumoral administration of ONYX-015, a replication-selective adenovirus, in patients with refractory head and neck cancer
-
Nemunaitis J, Khuri F, Ganly I, et al: Phase II trial of intratumoral administration of ONYX-015, a replication-selective adenovirus, in patients with refractory head and neck cancer. J Clin Oncol 19:289-298, 2001
-
(2001)
J Clin Oncol
, vol.19
, pp. 289-298
-
-
Nemunaitis, J.1
Khuri, F.2
Ganly, I.3
-
50
-
-
0030790684
-
Prostate attenuated replication competent adenovirus (ARCA) CN706: A selective cytotoxic for prostate-specific antigen-positive prostate cancer cells
-
Rodriguez R, Schuur ER, Lim HY, et al: Prostate attenuated replication competent adenovirus (ARCA) CN706: a selective cytotoxic for prostate-specific antigen-positive prostate cancer cells. Cancer Res 57:2559-2563, 1997
-
(1997)
Cancer Res
, vol.57
, pp. 2559-2563
-
-
Rodriguez, R.1
Schuur, E.R.2
Lim, H.Y.3
-
51
-
-
0035879042
-
CV706, a prostate cancer-specific adenovirus variant, in combination with radiotherapy produces synergistic antitumor efficacy without increasing toxicity
-
Chen Y, DeWeese T, Dilley J, et al: CV706, a prostate cancer-specific adenovirus variant, in combination with radiotherapy produces synergistic antitumor efficacy without increasing toxicity. Cancer Res 61:5453-5460, 2001
-
(2001)
Cancer Res
, vol.61
, pp. 5453-5460
-
-
Chen, Y.1
DeWeese, T.2
Dilley, J.3
-
52
-
-
1542704139
-
Novel therapeutic strategies in prostate cancer management using gene therapy in combination with radiation therapy
-
Collis SJ, Khater K, DeWeese TL: Novel therapeutic strategies in prostate cancer management using gene therapy in combination with radiation therapy. World J Urol 21:275-289, 2003
-
(2003)
World J Urol
, vol.21
, pp. 275-289
-
-
Collis, S.J.1
Khater, K.2
DeWeese, T.L.3
|