Dehydroepiandrosterone delays LDL oxidation in vitro and attenuates several oxLDL-induced inflammatory responses in endothelial cells

Inflammation and Allergy - Drug Targets

Volumn 6, Issue 3, 2007, Pages 174-182

  López Marure, Rebecca ^a   Huesca Gómez, Claudia ^a   Ibarra Sánchez, María de Jesús ^b   Zentella, Alejandro ^b   Pérez Méndez, Oscar ^a  

^a INSTITUTO NACIONAL DE CARDIOLOGÍA IGNACIO CHÁVEZ   (Mexico)

^b UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

AP 1; Cell adhesion; DHEA; Endothelial cells; Inflammation; LDL; NF B; ROS

Indexed keywords

CD31 ANTIGEN; CELL ADHESION MOLECULE; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; LOW DENSITY LIPOPROTEIN; OXIDIZED LOW DENSITY LIPOPROTEIN; PRASTERONE; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR AP 1; VASCULAR CELL ADHESION MOLECULE 1;

ANTIINFLAMMATORY ACTIVITY; ATHEROSCLEROSIS; CELL ACTIVATION; CELL ADHESION; CELL STRAIN U937; CHRONIC DISEASE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; HUMAN TISSUE; IN VITRO STUDY; INFLAMMATION; INFLAMMATORY DISEASE; INTRACELLULAR TRANSPORT; OXIDATION KINETICS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN TRANSPORT; REVIEW; UMBILICAL VEIN; VASCULAR ENDOTHELIUM;

ADJUVANTS, IMMUNOLOGIC; ANTI-INFLAMMATORY AGENTS; ANTIGENS, CD31; BLOTTING, WESTERN; CELL ADHESION; CELL ADHESION MOLECULES; CELLS, CULTURED; DATA INTERPRETATION, STATISTICAL; DEHYDROEPIANDROSTERONE; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENDOTHELIAL CELLS; FLOW CYTOMETRY; HUMANS; LIPOPROTEINS, LDL; NF-KAPPA B; OXIDATION-REDUCTION; REACTIVE OXYGEN SPECIES; TRANSCRIPTION FACTOR AP-1; TUMOR NECROSIS FACTOR-ALPHA; U937 CELLS; VASCULAR CELL ADHESION MOLECULE-1;

EID: 34648836405     PISSN: 18715281     EISSN: None     Source Type: Journal    
DOI: 10.2174/187152807781696428     Document Type: Review

References (46)

1. Schwartz, C.J., Valente, A.; Sprague, E.; Kelley, J.L.; Nerem, R.M. Clin. Cardiol., 1991, 2 Suppl 1, 1.
2. Steinberg, D.S.; Parthasarathy, S.; Carew, T.E.; Khoo, J.C.; Witztum, J.L. N. Engl. J. Med., 1989, 320, 915.
3. Regelson, W.; Kalimi, M.; Loria, M. In The biologic role of dehydroepiandrosterone (DHEA), Kalimi, M.; Regelson W., Ed.; Walter de Gruyter & Cc: New York, 1990; pp. 405-45.
4. Eich, D.M.; Nestler, J.E.; Johnson, D.E.; Dworkin, G.H.; Ko, D., Wechsler, A.S.; Hess, M.L. Circulation, 1993, 8, 261.
5. Barret-Connor, E.; Goodman-Gruen, D. Ann. N. Y. Acad. Sci., 1995, 774, 259.
6. Barret-Connor, E.; Khaw, K.T.; Yen, S.S. N. Engl. J. Med., 1986, 315, 1519.
7. Pelissier, M.A.; Trap, C.; Malewiak, M.I.; Morfin, R. Steroids, 2004, 69, 137.
8. Aksoy, Y.; Yapanoglu, T.; Aksou, H.; Yildirim, A.K. Urol. Res., 2004, 32, 93.
9. Yildirim, A.; Gumus, M.; Dalga, S.; Sabin, Y.N.; Akcay, F. Ann. Clin. Lab. Sci., 2003, 33, 459.
10. Gallo, M.; Aragno, M.; Gatto, V.; Tamagno, E.; Brignardello, E.; Manti, R.; Danni, O.; Boccuzzi, G. Eur. J. Endocrinol., 1999, 141, 35.
11. Khalil, A.; Lehoux, J.G.; Wagner, R.J.; Lesur, O.; Cruz, S.; Dupont, E.; Jay-Gerin, J.P.; Wallach, J.; Fülöp, T. Atherosclerosis, 1998, 136, 99.
12. Boccuzzi, G.; Aragno, M.; Seccia, M.; Brignardello, E.; Tamagno, E.; Albano, E.; Danni, O.; Bellomo, G. Free. Radic. Biol. Med., 1997, 22, 1289.
13. Khalil, A.; Fortin, J.P.; LeHoux, J.G.; Fulop, T. J. Lip. Res., 2000; 41, 1552.
14. Cominacini, L.; Garbin, U.; Pasini, A.F.; Stranieri, C.; Pellegrini, M.; Boccioletti, V.; Tosetti, L.; Lo Cascio, V. J. Hypertens., 1998, 16, 1913.
15. Zapata, E.; Ventura, J.L.; De la Cruz, K.; Rodriguez, E.; Damian, P.; Masso, F.; Montaño, L.F.; López-Marure, R. FEBS J., 2005, 272, 1343.
16. Huesca-Gómez, C.; Franco, M.; Luc, G.; Montano, L.F.; Masso, F:; Posadas-Romero C.; Pérez-Méndez, O. Metabolism, 2002, 51, 443.
17. Lowry, O.H.; Rosebrough, H.J.; Farr, A.L. J. Biol. Chem., 1951, 193, 265.
18. Rothe, G.; Valet, G. J. Leukoc. Biol., 1990, 47, 440.
19. Estrada-Bernal, A.; Mendoza-Milla, C.; Ventura-Gallegos, J.L.; Lopez-Bojorquez, L.N.; Miranda-Peralta, E.; Arechavaleta-Velasco, F.; Vadillo-Ortega, F.; Sánchez-Sáncbez, L.; Zentella-Dehesa, A. Cancer Lett., 2003, 191, 239.
20. Aoudjit, F.; Brochu, N.; Belanger, B.; Stratowa, C.; Hiscott, J.; Audette, M. Cell Growth Differ., 1997, 8, 335.
21. Brown, K.; Park, S.; Kanno, T.; Franzoso, G.; Siebenlist, U. Proc. Natl. Acad. Sci. USA., 1993, 90, 2532.
22. Adhikari, N.; Charles, N.; Lehmann, U.; Hall, J.L. Curr. Atheroscler. Rep., 2006, 8, 252.
23. Gordon, G.B.; Bush, D.E.; Weisman, H.F. J. Clin. Invest., 1988, 82, 712.
24. Taub, D.D. Cytokine Growth Factor Rev., 1996, 7, 355.
25. Collins, T. Lab. Invest., 1993, 68, 499.
26. Gutiérrez, G.; Mendoza, C.; Zapata, E.; Montiel, A.; Reyes, E.; Montano, L.F.; López-Marure, R. Atherosclerosis, 2007, 190, 90.
27. Birukov, K.G. Curr. Atheroscler. Rep., 2006, 8, 223.
28. Blankenberg, S.; Barbaux, S.; Tiret, L. Atherosclerosis, 2003, 170, 191.
29. Dwivedi, A.; Anggard, E.E.; Carrier, M.J. Biochem. Biophys. Res. Commun., 2001, 284, 239.
30. Ng, M.K.; Nakhla, S.; Baoutina, A.; Jessup, W.; Handelsman, D.J.; Celermajer, D.S. J. Am. Coll. Cardiol., 2003, 42, 1967.
31. Barkhausen, T.; Westphal, B.M.; Putz, C.; Krettek, C.; van Griensven, M. Crit. Care, 2006, 10, R109.
32. True, A.L.; Rahman, A.; Malik, A.B. Am. J. Physiol. Lung Cell Mol. Physiol., 2000, 279, L302.
33. Valen, G.; Yan, Z.Q.; Hansson, G.K. J. Am. Coll. Cardiol., 2001, 38, 307.
34. Thornburg, N.J.; Pathmanathan, R.; Raab-Traub, N. Cancer Res., 2003, 63, 8293.
35. Hatada, E.N.; Do, R.K.; Orlofsky, A.; Liou, H.C.; Prystowsky, M.; MacLennan, I.C.; Caamano, J.; Chen-Kiang, S. J. Immunol., 2003, 171, 761.
36. Ohlsson, B.G.; Englund, M.C.; Karlsson, A.L.; Knutsen, E.; Erixon, C.; Skribeck, H.; Liu, Y.; Bondjers, G.; Wiklund, O. J. Clin. Invest., 1996, 98, 78.
37. Chen, J.W.; Chen, Y.H.; Lin, S.J. Free Radic. Biol. Med., 2006, 40, 817.
38. Cominacini, L.; Anselmi, M.; Garbin, U.; Fratta Pasini, A.; Stranieri, C.; Fusaro, M.; Nava, C.; Agostoni, P.; Keta, D.; Zardini, P.; Sawamura, T.; Lo Cascio, V. J. Am. Coll. Cardiol., 2005, 46, 799.
39. Gan, W.H.; Din, G.X.; Chen, R.H. Xi. Bao. Yu. Fen. Zi. Mian. Yi. Xue. Za. Zhi., 2004, 20, 598.
40. de Nigris, F.; Gallo, L.; Sica, V.; Napoli, C. Basic Res. Cardiol., 2006, 101, 101.
41. Robbesyn, F.; Salvayre, R.; Negre-Salvayre, A. Free Radical Res., 2004, 38, 541.
42. Angel, P.; Karin, M. Biochim. Biophys. Acta, 1991, 1072, 129.
43. Turpaev, K.T. Mol. Biol. (Mosk), 2006, 40, 945.
44. Dashtaki, R.; Whorton, A.R.; Murphy, T.M.; Chitano, P.; Reed, W.; Kennedy, T.P. J. Pharmacol. Exp. Ther., 1998, 285, 876.
45. Wang, N.; Verna, L.; Hardy, S.; Forsayeth, J.; Zhu, Y.; Stemerman, M.B. Arterioscler. Thromb. Vasc. Biol., 1999, 19, 2078.
46. Wang, N.; Verna, L.; Liao, H.I; Ballard, A.; Zhu, Y.; Stemerman, M.B. Arterioscler. Thromb. Vasc. Biol., 2001, 21, 1414.