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Volumn 98, Issue 1, 1996, Pages 78-89

Oxidized low density lipoprotein inhibits lipopolysaccharide-induced binding of nuclear factor-κB to DNA and the subsequent expression of tumor necrosis factor-α and interleukin-1β in macrophages

Author keywords

atherosclerosis; gene expression; modified low density lipoproteins; oxysterols; transcription factors

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; OXIDIZED LOW DENSITY LIPOPROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR ALPHA;

EID: 0030056027     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/jci118780     Document Type: Article
Times cited : (167)

References (69)
  • 2
    • 0026325498 scopus 로고
    • Monocyte transmigration induced by modification of low density lipoprotein in cocultures of human aortic wall cells is due to induction of monocyte chemotactic protein 1 synthesis and is abolished by high density lipoprotein
    • Navab, M., S.S. Imes, S.Y. Hama, G.P. Hough, L.A. Ross, R.W. Bork, A.J. Valente, J.A. Berliner, D.C. Drinkwater, H. Laks, and A.M. Fogelman. 1991. Monocyte transmigration induced by modification of low density lipoprotein in cocultures of human aortic wall cells is due to induction of monocyte chemotactic protein 1 synthesis and is abolished by high density lipoprotein. J. Clin. Invest. 88:2039-2046.
    • (1991) J. Clin. Invest. , vol.88 , pp. 2039-2046
    • Navab, M.1    Imes, S.S.2    Hama, S.Y.3    Hough, G.P.4    Ross, L.A.5    Bork, R.W.6    Valente, A.J.7    Berliner, J.A.8    Drinkwater, D.C.9    Laks, H.10    Fogelman, A.M.11
  • 3
    • 0025231361 scopus 로고
    • Induction of endothelial cell expression of granulocyte and macrophage colony-stimulating factors by modified low-density lipoproteins
    • Rajavashisth, T.B., A. Andalibi, M.C. Territo, J.A. Berliner, M. Navab, A.M. Fogelman, and A.J. Lusis. 1990. Induction of endothelial cell expression of granulocyte and macrophage colony-stimulating factors by modified low-density lipoproteins. Nature (Lond.). 344:254-257.
    • (1990) Nature (Lond.) , vol.344 , pp. 254-257
    • Rajavashisth, T.B.1    Andalibi, A.2    Territo, M.C.3    Berliner, J.A.4    Navab, M.5    Fogelman, A.M.6    Lusis, A.J.7
  • 4
    • 0027381488 scopus 로고
    • Regulation of endothelial cell tissue factor expression by minimally oxidized LDL and lipopolysaccharide
    • Fei, H., J.A. Berliner, F. Parhami, and T.A. Drake. 1993. Regulation of endothelial cell tissue factor expression by minimally oxidized LDL and lipopolysaccharide. Arterioscler. Thromb. 13:1711-1717.
    • (1993) Arterioscler. Thromb. , vol.13 , pp. 1711-1717
    • Fei, H.1    Berliner, J.A.2    Parhami, F.3    Drake, T.A.4
  • 5
    • 0027170699 scopus 로고
    • Minimally modified low density lipoprotein-induced inflammatory responses in endothelial cells are mediated by cyclic adenosine monophosphate
    • Parhami, F., T.Z. Fang, A.M. Fogelman, A. Andalibi, M.C. Territo, and J.A. Berliner. 1993. Minimally modified low density lipoprotein-induced inflammatory responses in endothelial cells are mediated by cyclic adenosine monophosphate. J. Clin. Invest. 92:471-478.
    • (1993) J. Clin. Invest. , vol.92 , pp. 471-478
    • Parhami, F.1    Fang, T.Z.2    Fogelman, A.M.3    Andalibi, A.4    Territo, M.C.5    Berliner, J.A.6
  • 7
    • 0023192020 scopus 로고
    • Oxidatively modified low density lipoprotein: A potential role in recruitment and retention of mononcyte/macrophages during atherogenesis
    • Quinn, M.T., S. Parthasarathy, G.L. Fong, and D. Steinberg. 1987. Oxidatively modified low density lipoprotein: a potential role in recruitment and retention of mononcyte/macrophages during atherogenesis. Proc. Natl. Acad. Sci. USA. 84:2995-2998.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 2995-2998
    • Quinn, M.T.1    Parthasarathy, S.2    Fong, G.L.3    Steinberg, D.4
  • 9
    • 0028227192 scopus 로고
    • Cytotoxicity of oxidized LDL to porcine aortic smooth muscle cells is associated with the oxysterols 7-ketocholesterol and 7-hydroxycholesterol
    • Hughes, H., B. Mathews, M.L. Lenz, and J.R. Guyton. 1994. Cytotoxicity of oxidized LDL to porcine aortic smooth muscle cells is associated with the oxysterols 7-ketocholesterol and 7-hydroxycholesterol. Arterioscler. Thromb. 14:1177-1185.
    • (1994) Arterioscler. Thromb. , vol.14 , pp. 1177-1185
    • Hughes, H.1    Mathews, B.2    Lenz, M.L.3    Guyton, J.R.4
  • 10
    • 0018606973 scopus 로고
    • Injury to human endothelial cells induced by low density lipoproteins
    • Henriksen, T., S.A. Evensen, and B. Carlander. 1979. Injury to human endothelial cells induced by low density lipoproteins. Scand. J. Clin. Lab. Invest. 39:361-368.
    • (1979) Scand. J. Clin. Lab. Invest. , vol.39 , pp. 361-368
    • Henriksen, T.1    Evensen, S.A.2    Carlander, B.3
  • 11
    • 0026347097 scopus 로고
    • Inhibition of lipopolysaccharide-induced interleukin-1β mRNA expression in mouse macrophages by oxidized low density lipoprotein
    • Fong, L.G., T.A.T. Fong, and A.D. Cooper. 1991. Inhibition of lipopolysaccharide-induced interleukin-1β mRNA expression in mouse macrophages by oxidized low density lipoprotein. J. Lipid. Res. 32:1899-1909.
    • (1991) J. Lipid. Res. , vol.32 , pp. 1899-1909
    • Fong, L.G.1    Fong, T.A.T.2    Cooper, A.D.3
  • 12
    • 0025214424 scopus 로고
    • Oxidized low density lipoprotein suppresses the expression of tumor necrosis factor-α mRNA in stimulated murine peritoneal macrophages
    • Hamilton, T.A., M.A. Gouping, and G.M. Chisholm. 1990. Oxidized low density lipoprotein suppresses the expression of tumor necrosis factor-α mRNA in stimulated murine peritoneal macrophages. J. Immunol. 144:2343-2350.
    • (1990) J. Immunol. , vol.144 , pp. 2343-2350
    • Hamilton, T.A.1    Gouping, M.A.2    Chisholm, G.M.3
  • 13
    • 0025260779 scopus 로고
    • Regulation of tumor necrosis factor alpha transcription in macrophages: Involvement of four κB-like motifs and of constitutive and inducible forms of NF-κB
    • Collart, M.A., P. Baeuerle, and P. Vassalli. 1990. Regulation of tumor necrosis factor alpha transcription in macrophages: involvement of four κB-like motifs and of constitutive and inducible forms of NF-κB. Mol. Cell. Biol. 10:1498-1506.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 1498-1506
    • Collart, M.A.1    Baeuerle, P.2    Vassalli, P.3
  • 14
    • 0025186678 scopus 로고
    • κB-type enhancers are involved in lipopolysaccharide-mediated transcriptional activation of the tumor necrosis factor a gene in primary macrophages
    • Shakov, A.N., M.A. Collart, P. Vassalli, S.A. Nedospasov, and C.V. Jongeneel. 1990. κB-type enhancers are involved in lipopolysaccharide-mediated transcriptional activation of the tumor necrosis factor a gene in primary macrophages. J Exp. Med. 171:35-47.
    • (1990) J Exp. Med. , vol.171 , pp. 35-47
    • Shakov, A.N.1    Collart, M.A.2    Vassalli, P.3    Nedospasov, S.A.4    Jongeneel, C.V.5
  • 15
    • 0022930702 scopus 로고
    • Inducibility of κ immunoglobulin enhancer-binding protein NF-κB by a posttranslation mechanism
    • Sen, R., and D. Baltimore. 1986 Inducibility of κ immunoglobulin enhancer-binding protein NF-κB by a posttranslation mechanism. Cell. 47:921-928.
    • (1986) Cell , vol.47 , pp. 921-928
    • Sen, R.1    Baltimore, D.2
  • 16
    • 0027299890 scopus 로고
    • Regulation of interleukin-1β (IL-1β) gene by myobacterial components and lipopolysaccharide is mediated by two nuclear factor-IL-6 motifs
    • Zhang, Y., and W.N. Rom. 1993. Regulation of interleukin-1β (IL-1β) gene by myobacterial components and lipopolysaccharide is mediated by two nuclear factor-IL-6 motifs. Mol. Cell. Biol. 13:3831-3837.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 3831-3837
    • Zhang, Y.1    Rom, W.N.2
  • 17
    • 0024294357 scopus 로고
    • Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-κB transcription factor
    • Baeuerle, P.A., and D. Baltimore. 1988. Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-κB transcription factor. Cell. 53:211-217.
    • (1988) Cell , vol.53 , pp. 211-217
    • Baeuerle, P.A.1    Baltimore, D.2
  • 18
    • 0023724778 scopus 로고
    • IκB: A specific inhibitor of the NF-κB transcription factor
    • Baeuerle, P.A., and D. Baltimore. 1988. IκB: a specific inhibitor of the NF-κB transcription factor. Science (Wash. DC) 242:540-546.
    • (1988) Science (Wash. DC) , vol.242 , pp. 540-546
    • Baeuerle, P.A.1    Baltimore, D.2
  • 19
    • 0024355977 scopus 로고
    • In vitro activation and nuclear translocation of NF-κB catalyzed by cyclic AMP-dependent protein kinase and protein kinase C
    • Shirakawa, F., and S.B. Mizel. 1989. In vitro activation and nuclear translocation of NF-κB catalyzed by cyclic AMP-dependent protein kinase and protein kinase C. Mol. Cell. Biol. 9:2424-2430.
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 2424-2430
    • Shirakawa, F.1    Mizel, S.B.2
  • 20
    • 0025266685 scopus 로고
    • Activation in vitro of NF-κB by phosphorylation of its inhibitor IκB
    • Ghosh, S., and D. Baltimore. 1990. Activation in vitro of NF-κB by phosphorylation of its inhibitor IκB. Nature (Lond.). 344:678-682.
    • (1990) Nature (Lond.) , vol.344 , pp. 678-682
    • Ghosh, S.1    Baltimore, D.2
  • 21
    • 0025945893 scopus 로고
    • The rel-associated pp40 protein prevents DNA binding of rel and NF-κB: Relationship with IκBβ and regulation by phosphorylation
    • Kerr, L.D., J. Inoue, N. Davis, E. Link, P.A. Baeuerle, H.B. Bose Jr., and I.M. Verma. 1991. The rel-associated pp40 protein prevents DNA binding of rel and NF-κB: relationship with IκBβ and regulation by phosphorylation. Genes & Dev. 5:1464-1476.
    • (1991) Genes & Dev. , vol.5 , pp. 1464-1476
    • Kerr, L.D.1    Inoue, J.2    Davis, N.3    Link, E.4    Baeuerle, P.A.5    Bose Jr., H.B.6    Verma, I.M.7
  • 22
    • 0027618650 scopus 로고
    • Regulation of the NF-κB/rel transcription factor and IκB inhibitor system
    • Liou, H-C., and D. Baltimore. 1993. Regulation of the NF-κB/rel transcription factor and IκB inhibitor system. Curr. Opin. Cell Biol. 5:477-487.
    • (1993) Curr. Opin. Cell Biol. , vol.5 , pp. 477-487
    • Liou, H.-C.1    Baltimore, D.2
  • 23
    • 0025720735 scopus 로고
    • The role of jun, fos and the AP-1 complex in cell-proliferation and transformation
    • Angel, P., and M. Karin. 1991. The role of jun, fos and the AP-1 complex in cell-proliferation and transformation. Biochim. Biophys. Acta. 1072:129-157.
    • (1991) Biochim. Biophys. Acta , vol.1072 , pp. 129-157
    • Angel, P.1    Karin, M.2
  • 24
    • 0028322193 scopus 로고
    • Signal transduction from the cell surface to the nucleus through the phosphorylation of transcription factors
    • Karin, M. 1994. Signal transduction from the cell surface to the nucleus through the phosphorylation of transcription factors. Curr. Opin. Cell Biol. 6:415-424.
    • (1994) Curr. Opin. Cell Biol. , vol.6 , pp. 415-424
    • Karin, M.1
  • 26
    • 0024206625 scopus 로고
    • Isolation and properties of cDNA clones encoding SRF, a transcription factor that binds to the c-fos serum responsive element
    • Norman, C., M. Runswick, R. Pollock, and R. Treisman. 1988. Isolation and properties of cDNA clones encoding SRF, a transcription factor that binds to the c-fos serum responsive element. Cell. 55:989-1003.
    • (1988) Cell , vol.55 , pp. 989-1003
    • Norman, C.1    Runswick, M.2    Pollock, R.3    Treisman, R.4
  • 27
    • 0026556859 scopus 로고
    • Characterization of SAP-1, a protein recruited by serum response factor to the c-fos serum response element
    • Dalton, S., and R. Treisman. 1992. Characterization of SAP-1, a protein recruited by serum response factor to the c-fos serum response element. Cell. 68:597-612.
    • (1992) Cell , vol.68 , pp. 597-612
    • Dalton, S.1    Treisman, R.2
  • 28
    • 0027297647 scopus 로고
    • The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain
    • Marais, R., J. Wynne, and R. Treisman. 1993. The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain. Cell. 73:381-393.
    • (1993) Cell , vol.73 , pp. 381-393
    • Marais, R.1    Wynne, J.2    Treisman, R.3
  • 29
    • 0025160847 scopus 로고
    • Effects of oxidatively modified LDL on cholesterol esterfication in cultured macrophages
    • Zhang H., H.J.K. Basra, and U.P. Steinbrecher 1990. Effects of oxidatively modified LDL on cholesterol esterfication in cultured macrophages. J. Lipid Res. 31:1361-1369.
    • (1990) J. Lipid Res. , vol.31 , pp. 1361-1369
    • Zhang, H.1    Basra, H.J.K.2    Steinbrecher, U.P.3
  • 31
    • 0023044208 scopus 로고
    • Membrane properties of oxysterols, interfacial orientation, influence on membrane permeability and redistribution between membranes
    • Theunissen, J.J.H., R.L. Jackson, H.J.M. Kempen, and R.A. Demel. 1986. Membrane properties of oxysterols, interfacial orientation, influence on membrane permeability and redistribution between membranes. Biochim. Biophys. Acta. 860:66-74.
    • (1986) Biochim. Biophys. Acta , vol.860 , pp. 66-74
    • Theunissen, J.J.H.1    Jackson, R.L.2    Kempen, H.J.M.3    Demel, R.A.4
  • 32
    • 0030060474 scopus 로고    scopus 로고
    • Oxysterols present in atherosclerotic tissue decrease the expression of lipoprotein lipase messenger RNA in human monocyte-derived macrophages
    • Mattsson Hultén, L., H. Lindmark, U. Diczfalusy, I. Björkhem, M. Ottosson, Y. Liu, G. Bondjers, and O. Wiklund. 1996. Oxysterols present in atherosclerotic tissue decrease the expression of lipoprotein lipase messenger RNA in human monocyte-derived macrophages. J. Clin. Invest. 97:461-468.
    • (1996) J. Clin. Invest. , vol.97 , pp. 461-468
    • Mattsson Hultén, L.1    Lindmark, H.2    Diczfalusy, U.3    Björkhem, I.4    Ottosson, M.5    Liu, Y.6    Bondjers, G.7    Wiklund, O.8
  • 33
    • 0016691608 scopus 로고
    • Cholesterol ester formation in cultured human fibroblasts: Stimulation by oxygenated sterols
    • Brown, M.S., and J.L. Goldstein. 1975. Cholesterol ester formation in cultured human fibroblasts: stimulation by oxygenated sterols. J. Biol. Chem. 250:4025-4027.
    • (1975) J. Biol. Chem. , vol.250 , pp. 4025-4027
    • Brown, M.S.1    Goldstein, J.L.2
  • 34
    • 0015036331 scopus 로고
    • Characterization of a new group of polar sterol from human atherosclerotic plaques
    • Brooks, C.J.W., G. Steel, J.D. Gilbert, and W.A. Harland. 1971. Characterization of a new group of polar sterol from human atherosclerotic plaques. Atherosclerosis. 13:223-237.
    • (1971) Atherosclerosis , vol.13 , pp. 223-237
    • Brooks, C.J.W.1    Steel, G.2    Gilbert, J.D.3    Harland, W.A.4
  • 35
    • 0015034778 scopus 로고
    • The occurence of a new group of polar sterol esters in various stages of human atherosclerosis
    • Harland, W.A., J.D. Gilbert, G. Steel, and C.J.W. Brooks. 1971. The occurence of a new group of polar sterol esters in various stages of human atherosclerosis. Atherosclerosis. 13:239-246.
    • (1971) Atherosclerosis , vol.13 , pp. 239-246
    • Harland, W.A.1    Gilbert, J.D.2    Steel, G.3    Brooks, C.J.W.4
  • 36
    • 0014817872 scopus 로고
    • Sterol metabolism IX, 26-hydroxycholesterol levels in the human aorta
    • Smith, L.L., and J.E. van Lier. 1970. Sterol metabolism IX, 26-hydroxycholesterol levels in the human aorta. Atherosclerosis. 12:1-14.
    • (1970) Atherosclerosis , vol.12 , pp. 1-14
    • Smith, L.L.1    Van Lier, J.E.2
  • 38
    • 0028134883 scopus 로고
    • 7-βhydroperoxycholest-5-en-3β-ol, a component of human atherosclerotic lesions, is the primary cytotoxin of oxidized human low density lipoprotein
    • Chisholm, G.M., G. Ma, K.C. Irwin, L.L. Martin, K.M. Gunderson, L.F. Linberg, D.W. Morel, and P.E. Dicorleto. 1994. 7-βhydroperoxycholest-5-en-3β-ol, a component of human atherosclerotic lesions, is the primary cytotoxin of oxidized human low density lipoprotein. Proc. Natl. Acad. Sci. USA. 91:11452-11456.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 11452-11456
    • Chisholm, G.M.1    Ma, G.2    Irwin, K.C.3    Martin, L.L.4    Gunderson, K.M.5    Linberg, L.F.6    Morel, D.W.7    Dicorleto, P.E.8
  • 40
    • 0016961001 scopus 로고
    • Isolation of lymphocytes, granulocytes and macrophages
    • Böyum, A. 1976. Isolation of lymphocytes, granulocytes and macrophages. Scand. J. Immunol. 5(Suppl. 5):9-15.
    • (1976) Scand. J. Immunol. , vol.5 , Issue.5 SUPPL. , pp. 9-15
    • Böyum, A.1
  • 41
    • 0018962592 scopus 로고
    • Isolation and partial characterization of polypeptide belonging to apolipoprotein B from low density lipoproteins in human plasma
    • Olofsson, S.-O., K. Boström, U. Svanberg, and G. Bondjers. 1980. Isolation and partial characterization of polypeptide belonging to apolipoprotein B from low density lipoproteins in human plasma. Biochemistry. 19:1059-1064.
    • (1980) Biochemistry , vol.19 , pp. 1059-1064
    • Olofsson, S.-O.1    Boström, K.2    Svanberg, U.3    Bondjers, G.4
  • 42
    • 0000061171 scopus 로고
    • Modification of low density lipoprotein by endothelial cells involves lipid peroxidation and degradation of low density lipoprotein phospholipids
    • Steinbrecher, U.P., S. Parthasarathy, D.S. Leake, J.L. Witzum, and D. Steinberg. 1984. Modification of low density lipoprotein by endothelial cells involves lipid peroxidation and degradation of low density lipoprotein phospholipids. Proc. Natl. Acad. Sci. USA. 81:3883-3887.
    • (1984) Proc. Natl. Acad. Sci. USA , vol.81 , pp. 3883-3887
    • Steinbrecher, U.P.1    Parthasarathy, S.2    Leake, D.S.3    Witzum, J.L.4    Steinberg, D.5
  • 43
    • 0017184389 scopus 로고
    • A rapid and a sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford, M.M. 1976. A rapid and a sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 44
    • 0016241915 scopus 로고
    • Binding and degradation of low density lipoproteins by cultured human fibroblasts: Comparison of cells from a normal and from patient with homozygous familial hypercholesterolemia
    • Goldstein, J.L., and M.S. Brown. 1974. Binding and degradation of low density lipoproteins by cultured human fibroblasts: comparison of cells from a normal and from patient with homozygous familial hypercholesterolemia. J. Biol. Chem. 249:5153-5162.
    • (1974) J. Biol. Chem. , vol.249 , pp. 5153-5162
    • Goldstein, J.L.1    Brown, M.S.2
  • 45
    • 0026632822 scopus 로고
    • Effect of arterial proteoglycans and glycosaminoglycans on low density lipoprotein oxidation and its uptake by human macrophages and arterial smooth muscle cells
    • Hurt-Camejo, E., G. Camejo, B. Rosengren, F. Lopez, C. Ahlström, G. Fager, and G. Bondjers. 1992. Effect of arterial proteoglycans and glycosaminoglycans on low density lipoprotein oxidation and its uptake by human macrophages and arterial smooth muscle cells. Arterioscler. Thromb. 12:569-583.
    • (1992) Arterioscler. Thromb. , vol.12 , pp. 569-583
    • Hurt-Camejo, E.1    Camejo, G.2    Rosengren, B.3    Lopez, F.4    Ahlström, C.5    Fager, G.6    Bondjers, G.7
  • 46
    • 0027269781 scopus 로고
    • 2 and antioxidants have opposite effects on activation of NF-κB and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor
    • 2 and antioxidants have opposite effects on activation of NF-κB and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor. EMBO (Eur. Mol Biol. Organ.) J. 12: 2005-2015.
    • (1993) EMBO (Eur. Mol Biol. Organ.) J. , vol.12 , pp. 2005-2015
    • Meyer, M.1    Schreck, R.2    Baeuerle, P.A.3
  • 47
    • 0023625090 scopus 로고
    • Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor
    • Angel, P., M. Imagawa, R. Chiu, B. Stein, R.J. Imbra, H.J. Rahmsdorf, C. Jonat, P. Herrlich, and M. Karin. 1987. Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor. Cell. 49:729-739.
    • (1987) Cell , vol.49 , pp. 729-739
    • Angel, P.1    Imagawa, M.2    Chiu, R.3    Stein, B.4    Imbra, R.J.5    Rahmsdorf, H.J.6    Jonat, C.7    Herrlich, P.8    Karin, M.9
  • 48
    • 0025012683 scopus 로고
    • Octamer-binding proteins in diverse hemopoietic cells
    • Cockerill, P.N., and S.P. Klinken. 1990. Octamer-binding proteins in diverse hemopoietic cells. Mol. Cell. Biol. 10:1293-1296.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 1293-1296
    • Cockerill, P.N.1    Klinken, S.P.2
  • 49
    • 0018639079 scopus 로고
    • Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease
    • Chirgwin, J.M., A.M. Przybyla, R.J. MacDonald, and W.J. Rutter. 1979. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry. 18:5294-5298.
    • (1979) Biochemistry , vol.18 , pp. 5294-5298
    • Chirgwin, J.M.1    Przybyla, A.M.2    MacDonald, R.J.3    Rutter, W.J.4
  • 50
    • 0024828121 scopus 로고
    • Quantification of mRNA by the polymerase chain reaction
    • Wang, A.M., M.V. Doyle, and D.F. Mark. 1989. Quantification of mRNA by the polymerase chain reaction. Proc. Natl. Acad. Sci. USA. 86:9717-9721.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 9717-9721
    • Wang, A.M.1    Doyle, M.V.2    Mark, D.F.3
  • 51
    • 0027435105 scopus 로고
    • Expression of lipoprotein lipase mRNA and secretion in macrophages isolated from human atherosclerotic aorta
    • Mattsson, L., H. Johansson, M. Ottosson, O. Bondjers, and O. Wiklund. 1993. Expression of lipoprotein lipase mRNA and secretion in macrophages isolated from human atherosclerotic aorta. J. Clin. Invest. 92:1759-1765.
    • (1993) J. Clin. Invest. , vol.92 , pp. 1759-1765
    • Mattsson, L.1    Johansson, H.2    Ottosson, M.3    Bondjers, O.4    Wiklund, O.5
  • 52
    • 0028940327 scopus 로고
    • The effects of oxidized low density lipoproteins on inducible mouse macrophage gene expression are gene and stimulus dependent
    • Hamilton, T.A., J.A. Major, and G.M. Chisholm. 1995. The effects of oxidized low density lipoproteins on inducible mouse macrophage gene expression are gene and stimulus dependent. J. Clin. Invest. 95:2020-2027.
    • (1995) J. Clin. Invest. , vol.95 , pp. 2020-2027
    • Hamilton, T.A.1    Major, J.A.2    Chisholm, G.M.3
  • 53
    • 0025022957 scopus 로고
    • The production of human interleukin-1beta by blood monocytes
    • M. Melli and L. Parente, editors. Wiley-Liss, Inc., New York
    • Newton, R.C. 1990. The production of human interleukin-1beta by blood monocytes. In Cytokines and Lipocortins in inflammation and Differentiation. M. Melli and L. Parente, editors. Wiley-Liss, Inc., New York. 349:217-228.
    • (1990) Cytokines and Lipocortins in Inflammation and Differentiation , vol.349 , pp. 217-228
    • Newton, R.C.1
  • 54
    • 0025069619 scopus 로고
    • Regulation of cachectin biosynthesis occurs at multiple levels
    • M. Melli and L. Parente. Editors. Wiley-Liss, Inc., New York
    • Beutler, B. 1990. Regulation of cachectin biosynthesis occurs at multiple levels. In Cytokines and Lipocortins in Inflammation and Differentiation. M. Melli and L. Parente. Editors. Wiley-Liss, Inc., New York. 349:229-240.
    • (1990) Cytokines and Lipocortins in Inflammation and Differentiation , vol.349 , pp. 229-240
    • Beutler, B.1
  • 55
    • 0020972414 scopus 로고
    • Lipoprotein metabolism in macrophage: Implications for the cholesterol deposition in atherosclerosis
    • Brown, M.S., and J.L. Goldstein, 1983. Lipoprotein metabolism in macrophage: implications for the cholesterol deposition in atherosclerosis. Annu. Rev. Biochem. 52:223-261.
    • (1983) Annu. Rev. Biochem. , vol.52 , pp. 223-261
    • Brown, M.S.1    Goldstein, J.L.2
  • 56
    • 0025850232 scopus 로고
    • Oxidation of cholesterol moiety of low density lipoprotein in the presence of human endothelial cells or Cu2+ ions: Identification of major products and their effects
    • Bhadra, S., M.A.Q. Arshad, Z. Rymaszewski, E. Norman, R. Wherley, and M.T.R. Subbiah. 1991. Oxidation of cholesterol moiety of low density lipoprotein in the presence of human endothelial cells or Cu2+ ions: identification of major products and their effects. Biochem. Biophys. Res. Commun. 176:431-440.
    • (1991) Biochem. Biophys. Res. Commun. , vol.176 , pp. 431-440
    • Bhadra, S.1    Arshad, M.A.Q.2    Rymaszewski, Z.3    Norman, E.4    Wherley, R.5    Subbiah, M.T.R.6
  • 57
    • 0025911657 scopus 로고
    • Varying susceptibility of different low density lipoproteins to oxidative modification
    • Jialal, I., D.A. Freeman, and S.M. Grundy. 1991. Varying susceptibility of different low density lipoproteins to oxidative modification. Arterioscler. & Thromb. 11:482-488.
    • (1991) Arterioscler. & Thromb. , vol.11 , pp. 482-488
    • Jialal, I.1    Freeman, D.A.2    Grundy, S.M.3
  • 58
    • 0001070512 scopus 로고
    • Influence of cholesterol oxides and antioxidants on prostacyclin production by cultured endothelial cells
    • Hu, B., S. Peng, D. Brubaker, and R.J. Morin. 1990. Influence of cholesterol oxides and antioxidants on prostacyclin production by cultured endothelial cells. FASEB J. 4:3734.
    • (1990) FASEB J. , vol.4 , pp. 3734
    • Hu, B.1    Peng, S.2    Brubaker, D.3    Morin, R.J.4
  • 59
    • 0026034450 scopus 로고
    • Toxicity of oxygenated cholesterol derivatives toward cultured human umbilical vein endothelial cells
    • Pettersen, K.S., K.M. Boberg, A. Stabursvik, and H. Prydz. 1991. Toxicity of oxygenated cholesterol derivatives toward cultured human umbilical vein endothelial cells. Arteroscler. & Thromb. 11:423-428.
    • (1991) Arteroscler. & Thromb. , vol.11 , pp. 423-428
    • Pettersen, K.S.1    Boberg, K.M.2    Stabursvik, A.3    Prydz, H.4
  • 60
    • 0026098699 scopus 로고
    • Uptake, metabolism and cytotoxicity of isomeric cholesterol-5, 6-epoxides in rabbit aortic endothelial cells
    • Sevanian, A., J. Berliner, and H. Peterson. 1991. Uptake, metabolism and cytotoxicity of isomeric cholesterol-5, 6-epoxides in rabbit aortic endothelial cells. J. Lipid Res. 32:147-155.
    • (1991) J. Lipid Res. , vol.32 , pp. 147-155
    • Sevanian, A.1    Berliner, J.2    Peterson, H.3
  • 61
    • 0027393276 scopus 로고
    • Cytotoxicity of oxysterols on cultured smooth muscle cells from human umbilical arteries
    • Zhou, Q., T.L. Smith, and F.A. Kummerow. 1993. Cytotoxicity of oxysterols on cultured smooth muscle cells from human umbilical arteries. Proc. Soc. Exp. Biot. Med. 202:75-80.
    • (1993) Proc. Soc. Exp. Biot. Med. , vol.202 , pp. 75-80
    • Zhou, Q.1    Smith, T.L.2    Kummerow, F.A.3
  • 63
    • 0028293275 scopus 로고
    • Multiple lipid oxidation products in low density lipoproteins induce interleukin-1beta release from human blood mononuclear cells
    • Thomas, C.E., R.L. Jackson, D.F. Ohlweiler, and G. Ku. 1994. Multiple lipid oxidation products in low density lipoproteins induce interleukin-1beta release from human blood mononuclear cells. J. Lipid. Res. 35:417-427.
    • (1994) J. Lipid. Res. , vol.35 , pp. 417-427
    • Thomas, C.E.1    Jackson, R.L.2    Ohlweiler, D.F.3    Ku, G.4
  • 64
    • 0024603895 scopus 로고
    • Beyond cholesterol: Modifications of low-density lipoprotein that increase its atherogenicity
    • Steinberger, D., S. Parthasarathy, T.E. Carew, J.C. Khoo, and J.L. Witzum. 1989. Beyond cholesterol: modifications of low-density lipoprotein that increase its atherogenicity. N. Engl. J. Med. 320:915-924.
    • (1989) N. Engl. J. Med. , vol.320 , pp. 915-924
    • Steinberger, D.1    Parthasarathy, S.2    Carew, T.E.3    Khoo, J.C.4    Witzum, J.L.5
  • 65
    • 0028353961 scopus 로고
    • Lysophosphatidylcholine in oxidized low-density lipoprotein increases endothelial susceptibility to polymorphonuclear leucocyte-induced endothelial dysfunction in porcine coronary arteries. Role of protein kinase C
    • Sugiyama, S., K. Kugiyama, M. Ohgushi, K. Fujimoto, and H. Yasue. 1994. Lysophosphatidylcholine in oxidized low-density lipoprotein increases endothelial susceptibility to polymorphonuclear leucocyte-induced endothelial dysfunction in porcine coronary arteries. Role of protein kinase C. Circ. Res. 74:565-575.
    • (1994) Circ. Res. , vol.74 , pp. 565-575
    • Sugiyama, S.1    Kugiyama, K.2    Ohgushi, M.3    Fujimoto, K.4    Yasue, H.5
  • 66
    • 0028879819 scopus 로고
    • Role of transcriptional activation of IκBα in mediation in immunosuppression by glucocorticoids
    • Scheinman, R.I., P.C. Cogswell, A.K. Lofquist, and A.S. Baldwin. 1995. Role of transcriptional activation of IκBα in mediation in immunosuppression by glucocorticoids. Science (Wash. DC). 270:283-286.
    • (1995) Science (Wash. DC) , vol.270 , pp. 283-286
    • Scheinman, R.I.1    Cogswell, P.C.2    Lofquist, A.K.3    Baldwin, A.S.4
  • 67
    • 0028867899 scopus 로고
    • Immunosuppression by glucocorticoids: Inhibition of NF-κB activity through induction of IκB synthesis
    • Auphan, N., J.A. DiDonato, C. Rosette, A. Helmberg, and M. Karin. 1995. Immunosuppression by glucocorticoids: Inhibition of NF-κB activity through induction of IκB synthesis. Science (Wash. DC). 270:286-290.
    • (1995) Science (Wash. DC) , vol.270 , pp. 286-290
    • Auphan, N.1    Didonato, J.A.2    Rosette, C.3    Helmberg, A.4    Karin, M.5
  • 68
    • 0029130938 scopus 로고
    • Oxidized LDL induces transcription factor acivator protein-1 but inhibits activation of nuclear factor-κB in human vascular smooth muscle cells
    • Ares, M.P.S., B. Kallin, P. Eriksson, and J. Nilsson. 1995. Oxidized LDL induces transcription factor acivator protein-1 but inhibits activation of nuclear factor-κB in human vascular smooth muscle cells. Arterioscler. Thromb. Vasc. Biol. 15:1584-1590.
    • (1995) Arterioscler. Thromb. Vasc. Biol. , vol.15 , pp. 1584-1590
    • Ares, M.P.S.1    Kallin, B.2    Eriksson, P.3    Nilsson, J.4
  • 69
    • 0029299438 scopus 로고
    • The response-to-retention hypothesis of early atherogenesis
    • Williams, K.J., and I. Tabas. 1995. The response-to-retention hypothesis of early atherogenesis. Arterioscler. Thromb. Vasc. Biol. 15:551-561.
    • (1995) Arterioscler. Thromb. Vasc. Biol. , vol.15 , pp. 551-561
    • Williams, K.J.1    Tabas, I.2


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