A mutant of Mycobacterium tuberculosis lacking the 19-kDa lipoprotein Rv3763 is highly attenuated in vivo but retains potent vaccinogenic properties

Vaccine

Volumn 25, Issue 41, 2007, Pages 7153-7159

  Henao Tamayo, Marcela ^a   Junqueira Kipnis, Ana Paula ^a   Ordway, Diane ^a   Gonzales Juarrero, Mercedes ^a   Stewart, Graham R ^b   Young, Douglas B ^b   Wilkinson, Robert J ^b   Basaraba, Randall J ^a   Orme, Ian M ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

19 kDa Lipoprotein; Mouse model; Tuberculosis; Vaccination

Indexed keywords

BCG VACCINE; GAMMA INTERFERON; LIPOPROTEIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

AEROSOL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL GROWTH; BACTERIUM CULTURE; BCG VACCINATION; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; CONTROLLED STUDY; FEMALE; IN VITRO STUDY; INOCULATION; LUNG ALVEOLUS CELL; MACROPHAGE; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

AEROSOLS; ANIMALS; BACTERIAL PROTEINS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; COLONY COUNT, MICROBIAL; FEMALE; GENE DELETION; HISTOCOMPATIBILITY ANTIGENS CLASS II; INTERFERON TYPE II; LIPOPROTEINS; LUNG; MACROPHAGES; MICE; MYCOBACTERIUM TUBERCULOSIS; TUBERCULOSIS; VIRULENCE;

EID: 34648828887     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2007.07.042     Document Type: Article

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