Deletion of the 19kDa antigen does not alter the protective efficacy of BCG

Tubercle and Lung Disease

Volumn 80, Issue 6, 2000, Pages 243-247

  Yeremeev, V V ^a   Stewart, G R ^b   Neyrolles, O ^b   Skrabal, K ^b   Avdienko, V G ^a   Apt, A S ^a   Young, D B ^b  

^a CENTRAL TUBERCULOSIS RESEARCH INSTITUTE   (Russian Federation)

^b IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; BCG VACCINE; LIPOPROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; DRUG STRUCTURE; FEMALE; GENE DELETION; MOUSE; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS; MYCOBACTERIUM VACCAE; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; TUBERCULOSIS; VACCINATION;

EID: 0034485055     PISSN: 09628479     EISSN: None     Source Type: Journal    
DOI: 10.1054/tuld.2000.0252     Document Type: Article

References (9)

1. Induction of a type I immune response to a recombinant antigen from Mycobacterium tuberculosis expressed in Mycobacterium vaccae
2. The 19-kDa antigen and protective immunity in a murine model of tuberculosis
3. Vaccination with recombinant vaccinia viruses protects mice against Mycobacterium tuberculosis infection
4. Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors
5. Transformation of mycobacterial species using hygromycin resistance as selectable marker
6. Expression of the Bacillus subtilis sacB gene confers sucrose sensitivity on mycobacteria
7. Expression of the Mycobacterium tuberculosis 19-kilodalton antigen in Mycobacterium smegmatis: Immunological analysis and evidence of glycosylation
8. Lack of production of the 19kDa glycolipoprotein in certain strains of Mycobacterium tuberculosis
9. Site-directed mutagenesis of the 19-kilodalton lipoprotein antigen reveals no essential role for the protein in the growth and virulence of Mycobacterium intracellulare