Ultrasound contrast agents: Pharmaceutical drug safety and bioeffects;Ultraschallkontrastmittel: Arzneimittelsicherheit und bioeffekte

Radiologe

Volumn 47, Issue 9, 2007, Pages 800-807

  Krix, M ^a,b,c   Jenne, J W ^c  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b NONE

^c NONE   (Germany)

Author keywords

Bioeffects; Cavitation; Nephrotoxity; Safety; Sonography; Ultrasound contrast agents (USCA)

Indexed keywords

ECHO CONTRAST MEDIUM;

ALLERGIC REACTION; BLOOD VESSEL INJURY; CLINICAL PRACTICE; CONTRAST ENHANCEMENT; DIAGNOSTIC PROCEDURE; DNA DAMAGE; DRUG SAFETY; ECHOCARDIOGRAPHY; HUMAN; IN VITRO STUDY; IN VIVO STUDY; KIDNEY FAILURE; NONHUMAN; PETECHIA; REVIEW;

ANIMALS; CELLS, CULTURED; CONTRAST MEDIA; DRUG HYPERSENSITIVITY; ECHOCARDIOGRAPHY; HUMANS; KIDNEY; KIDNEY DISEASES; MODELS, THEORETICAL; RISK FACTORS; SAFETY; ULTRASONOGRAPHY;

EID: 34648814024     PISSN: 0033832X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00117-007-1544-2     Document Type: Review

References (64)

1. Albrecht T, Hohmann J (2003) Ultrasound contrast agents. Radiologe 43: 793-804
2. Amon U (1997) Pathophysiologische und immunologische Mechanismen kontrastmittelinduzierter anaphylaktoider Sofortreaktionen - eine Übersicht. Akt Radiol 7: 145-148
3. Apfel RE, Holland CK (1991) Gauging the likelihood of cavitation from short-pulse, low-duty cycle diagnostic ultrasound. Ultrasound Med Biol 17: 179-185
4. Barnett SB, Duck F, Ziskin M (2007) Recommendations on the safe use of ultrasound contrast agents. Ultrasound Med Biol 33: 173-174
5. Barnett SB, Duck F, Ziskin M (2007) WFUMB symposium on safety of ultrasound in medicine: conclusions and recommendations on biological effects and safety of ultrasound contrast agents. Ultrasound Med Biol 33: 233-234
6. Becher H (2002) Contrast echocardiography: clinical applications and future prospects. Herz 27: 201-216
7. Behm CZ, Lindner JR (2006) Cellular and molecular imaging with targeted contrast ultrasound. Ultrasound Q 22: 67-72
8. Bekeredjian R, Grayburn, PA, Shohet RV (2005) Use of ultrasound contrast agents for gene or drug delivery in cardiovascular medicine. J Am Coll Cardiol 45: 329-335
9. Birnbaum Y, Luo H, Nagai T et al. (1998) Noninvasive in vivo clot dissolution without a thrombolytic drug: recanalization of thrombosed iliofemoral arteries by transcutaneous ultrasound combined with intravenous infusion of microbubbles. Circulation 97: 130-134
10. Blomley M, Albrecht T, Cosgrove DO et al. (1998) Stimulated acoustic emission in the liver parenchyma with ultrasound contrast agent levovist. Lancet 351: 568
11. Borges AC, Walde T, Reibis RK et al. (2002) Does contrast echocardiography with optison induce myocardial necrosis in humans? J Am Soc Echocardiogr 15: 1080-1086
12. Bouakaz A, de Jong N (2007) WFUMB safety symposium on echo-contrast agents: nature and types of ultrasound contrast agents. Ultrasound Med Biol 33: 187-196
13. Correas JM, Bridal L, Lesavre A et al. (2001) Ultrasound contrast agents: properties, principles of action, tolerance, and artefacts. Eur Radiol 11: 1316-1328
14. Correas JM, Claudon M, Tranquart F, Helenon O (2003) Contrast-enhanced ultrasonography: renal applications. J Radiol 84: 2041-2054
15. Dalecki D, Keller BB, Carstensen EL et al. (1991) Thresholds for premature ventricular contractions in frog hearts exposed to lithotripter fields. Ultrasound Med Biol 17: 341-346
16. Dalecki D, Raeman CH, Child SZ et al. (1997) Hemolysis in vivo from exposure to pulsed ultrasound. Ultrasound Med Biol 23: 307-313
17. Dalecki D (2007) WFUMB safety symposium on echo-contrast agents: bioeffects of ultrasound contrast agents in vivo. Ultrasound Med Biol 33: 205-213
18. Dayton PA, Lindner JR, Chomas JE et al. (1999) Ultrasound contrast agents phagocytosed by neutrophils demonstrate acoustic activity. In: Schneider SC, Levy M, McAvoy Br (eds) 1999 IEEE Ultrasonics Symposium Proceedings. Institue of Electrical and Electonic Engeneers, New York, pp 1705-1708
19. Debus J, Spoo J, Jenne J et al. (1999) Sonochemical induced radicals generated by pulsed high-energy ultrasound in vitro and in vivo. Ultrasound Med Biol 25: 301-306
20. Delorme S, Krix M, Albrecht T (2006) Ultrasound contrast media - principles and clinical applications. Rofo 178: 155-164
21. Everbach EC, Makin IR, Azadniv M, Meltzer RS (1997) Correlation of ultrasound-induced hemolysis with cavitation detector output in vitro. Ultrasound Med Biol 23: 619-624
22. Everbach EC, Makin IR, Francis CW, Meltzer RS (1998) Effect of acoustic cavitation on platelets in the presence of an echo-contrast agent. Ultrasound Med Biol 24: 129-136
23. Frauscher F, Klauser A, Berger AP et al. (2003) The value of ultrasound (US) in the diagnosis of prostate cancer. Radiologe 43: 455-463
24. Goertz DE, de Jong N, van der Steen AF (2007) Attenuation and size distribution of definity© and manipulated definity© populations. Ultrasound Med Biol: Epub ahead of print
25. Greis CH, Dietrich CF (2005) Ultraschallkontrastmittel und signalverstärkende Sonographie. In: Dietrich CF (Hrsg) Endoskopischer Ultraschall - Eine Einführung. Schnetztor, Konstanz, S 324-346
26. Honda H, Zhao QL, Kondo T (2002) Effects of dissolved gases and an echo contrast agent on apoptosis induced by ultrasound and its mechanism via the mitochondria-caspase pathway. Ultrasound Med Biol 28: 673-682
27. Hynynen K, McDannold N, Vykhodtseva N, Jolesz FA (2001) Noninvasive MR imaging-guided focal opening of the blood-brain barrier in rabbits. Radiology 220: 640-646
28. Jakobsen J, Oyen R, Thomsen HS, Morcos SK (2005) Safety of ultrasound contrast agents. Eur Radiol 15: 941-945
29. Jenne J (2001) Kavitation in biologischem Gewebe. Ultraschall Med 22: 200-207
30. Jenne JW, Martin-Villalba A, Flechsig P et al. (2007) Reversible opening of the BBB with focused ultrasound and SonoVue In: NN (eds) Therapeutic ultrasound. 7th international Symposium on Therapeutic Ultrasound. American Institute of Physics, Melville, New York
31. Kirchin MA, Runge VM (2003) Contrast agents for magnetic resonance imaging: safety update. Top Magn Reson Imaging 14: 426-435
32. Klauser A, Frauscher F, Schirmer M et al. (2002) The value of contrast-enhanced color Doppler ultrasound in the detection of vascularization of finger joints in patients with rheumatoid arthritis. Arthritis Rheum 46: 647-653
33. Kobayashi N, Yasu T, Yamada S et al. (2002) Endothelial cell injury in venule and capillary induced by contrast ultrasonography. Ultrasound Med Biol 28: 949-956
34. Koch S, Pohl P, Cobet U, Rainov NG (2000) Ultrasound enhancement of liposome-mediated cell transfection is caused by cavitation effects. Ultrasound Med Biol 26: 897-903
35. Korosoglou G, da Silva KG, Hansen A et al. (2004) Ultrasound contrast agents can influence the respiratory burst activity of human neutrophil granulocytes. Ultrasound Med Biol 30: 75-81
36. Krix M, Weber MA, Krakowski-Roosen H et al. (2005) Assessment of skeletal muscle perfusion using contrast-enhanced ultrasonography. J Ultrasound Med 24: 431-441
37. Kudo N, Miyaoka T, Okada K et al. (2002) Study on mechanism of cell damage caused by microbubbles exposed to ultrasound. Proc. IEEE Ultrasonics Symposium 1351-1354; ISBN No. 0-7803-7583-1
38. Li P, Cao LQ, Dou CY et al. (2003) Impact of myocardial contrast echocardiography on vascular permeability: an in vivo dose response study of delivery mode, pressure amplitude and contrast dose. Ultrasound Med Biol 29: 1341-1349
39. Lindner JR, Coggins MP, Kaul S et al. (2000) Microbubble persistence in the microcirculation during ischemia/reperfusion and inflammation is caused by integrin - and complement-mediated adherence to activated leukocytes. Circulation 101: 668-675
40. Lindner JR, Song J, Jayaweera AR et al. (2002) Microvascular rheology of definity microbubbles after intra-arterial and intravenous administration. J Am Soc Echocardiogr 15: 396-403
41. Maurer M, Linker R, Reinhardt M, Hauff P (2005) Possible target specific molecular imaging with ultrasound contrast agents. Radiologe 45: 560-568
42. Miller DL, Thomas RM, Buschborn RL (1995) Comet assay reveals DNA strand breaks induced by ultrasonic cavitation in vivo. Ultrasound Med Biol 21: 841-848
43. Miller DL, Thomas RM (1995) Ultrasound contrast agents nucleate inertial cavitation in vitro. Ultrasound Med Biol 21: 1059-1065
44. Miller DL, Gies RA (1998) Gas-body-based contrast agent enhances vascular bioeffects of 1.09 MHz ultrasound on mouse intestine. Ultrasound Med Biol 24: 1201-1208
45. Miller DL (2007) WFUMB safety symposium on echo-contrast agents: in vitro bioeffects. Ultrasound Med Biol 33: 197-204
46. Molina CA, Ribo M, Rubiera M et al. (2006) Microbubble administration accelerates clot lysis during continuous 2-MHz ultrasound monitoring in stroke patients treated with intravenous tissue plasminogen activator. Stroke 37: 425-429
47. Morcos SK, Thomsen HS (2001) Adverse reactions to iodinated contrast media. Eur Radiol 11: 1267-1275
48. Ostensen J, Hede R, Myreng Y et al. (1992) Intravenous injection of Albunex microspheres causes thromboxane mediated pulmonary hypertension in pigs, but not in monkeys or rabbits. Acta Physiol Scand 144: 307-315
49. Piscaglia F, Bolondi L (2006) Italian Society for Ultrasound in Medicine and Biology (SIUMB) Study Group on Ultrasound Contrast Agents. The safety of Sonovue in abdominal applications: retrospective analysis of 23188 investigations. Ultrasound Med Biol 32: 1369-1375
50. Raeman CH, Dalecki D, Child SZ et al. (1997) Albunex does not increase the sensitivity of the lung to pulsed ultrasound. Echocardiography 14: 553-558
51. Rosenfeld E (2003) Nicht-thermische, nicht kavitative Wirkungen von Ultraschall. Ultraschall Med 24: 40-44
52. Schlachetzki F, Holscher T, Koch HJ et al. (2002) Observation on the integrity of the blood-brain barrier after microbubble destruction by diagnostic transcranial color-coded sonography. J Ultrasound Med 21: 419-429
53. Sieswerda GT, Kamp O, Visser CA (2000) Myocardial contrast echocardiography: clinical benefit and practical issues. Echocardiography 17: 25-36
54. Skyba DM, Price RJ, Linka AZ et al. (1998) Direct in vivo visualization of intravascular destruction of microbubbles by ultrasound and its local effects on tissue. Circulation 98: 290-293
55. Sokka SD, King R, Hynynen K (2003) MRI-guided gas bubble enhanced ultrasound heating in in vivo rabbit thigh. Phys Med Biol 48: 223-241
56. Suslick KS, Kemper KA (1993) The Effect of fluorocarbon gases on sonoluminescence: a failure of the electrical hypothesis. Ultrasonics 31: 463-465
57. Tran TA, Roger S, Le Guennec JY et al. (2007) Effect of ultrasound-activated microbubbles on the cell electrophysiological properties. Ultrasound Med Biol 33: 158-163
58. Van der Wouw PA, Brauns AC, Bailey SE et al. (2000) Premature ventricular contractions during triggered imaging with ultrasound contrast. J Am Soc Echocardiogr 13: 288-294
59. Wible JH jr, Galen KP, Wojdyla JK et al. (2002) Microbubbles induce renal hemorrhage when exposed to diagnostic ultrasound in anesthetized rats. Ultrasound Med Biol 28: 1535-1546
60. Wiesmann M, Meyer K, Albers T, Seidel G (2004) Parametric perfusion imaging with contrast-enhanced ultrasound in acute ischemic stroke. Stroke 35: 508-513
61. Williams AR, Wiggins RC, Wharram BL et al. (2007) Nephron injury induced by diagnostic ultrasound imaging at high mechanical index with gas body contrast agent, Ultrasound Med Biol: Epub ahead of print
62. Wu J (1998) Temperatur rise generated by ultrasound in the presence of contrast agents. Ultrasound Med Biol 24: 267-274
63. Xie F, Tsutsui JM, Gao L et al. (2007) Interaction of transthoracic ultrasound and intravenous microbubbles with cardiac mechanoreceptors. Ultrasound Med Biol 33: 136-144
64. Yu T, Wang G, Hu K et al. (2004) A microbubble agent improves the therapeutic efficiency of high intensity focused ultrasound: a rabbit kidney study. Urol Res 32: 14-19