Noninvasive in vivo clot dissolution without a thrombolytic drug: Recanalization of thrombosed iliofemoral arteries by transcutaneous ultrasound combined with intravenous infusion of microbubbles

Circulation

Volumn 97, Issue 2, 1998, Pages 130-134

  Birnbaum, Yochai ^a   Luo, Huai ^a   Nagai, Tomoo ^a   Fishbein, Michael C ^a   Peterson, Thomas M ^d   Li, Shouping ^b   Kricsfeld, David ^b   Porter, Thomas R ^b   Siegel, Robert J ^a,c  

^a CEDARS SINAI MEDICAL CENTER   (United States)

^b UNIVERSITY OF NEBRASKA AT OMAHA   (United States)

^c Department of Medicine   (United States)

^d NONE

Author keywords

Occlusion; Thrombosis; Ultrasonics

Indexed keywords

ALBUMIN; FLUOROCARBON; GLUCOSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY THROMBOSIS; ARTICLE; BLOOD CLOT LYSIS; CONTROLLED STUDY; FEMORAL ARTERY; ILIAC ARTERY; NONHUMAN; PRIORITY JOURNAL; RABBIT; ULTRASOUND THERAPY;

EID: 0000588373     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.97.2.130     Document Type: Article

References (6)

1. Porter TR, LeVeen RF, Fox R, Kricsfeld A, Xie F. Thrombolytic enhancement with perfluorocarbon-exposed sonicated dextrose albumin microbubbles. Am Heart J. 1996;132:964-968.
2. Steffen W, Fishbein MC, Luo H, Lee D-Y, Nita H, Cumberland DC, Tabak SW, Carbonne M, Maurer G, Siegel RJ. High intensity, low frequency catheter-delivered ultrasound dissolution of occlusive coronary artery thrombi: an in vitro and in vivo study. J Am Coll Cardiol. 1994;24: 1571-1579.
3. Porter TR, Xie F, Kilzer K. Intravenous perfluoropropane-exposed sonicated dextrose albumin produces myocardial contrast which correlates with coronary blood flow. J Am Soc Echocardiogr. 1995;8:710-718.
4. Luo H, Nishioka T, Fishbein MC, Cercek B, Forrester JS, Kim CJ, Berglund H, Siegel RJ. Transcutaneous ultrasound augments lysis of arterial thrombi in vivo. Circulation. 1996;94:775-778.
5. Nishioka T, Luo H, Fishbein MC, Cercek B, Forrester JS, Kim CJ, Berglund H, Siegel RJ. Dissolution of thrombotic arterial occlusion by high intensity low frequency ultrasound and dodecafluoropentane emulsion: in vitro and in vivo study. J Am Cell Cardiol. 1997;30:561-568.
6. Tachibana K, Tachibana S. Albumin microbubble echo-contrast material as an enhancer for ultrasound accelerated thrombolysis. Circulation. 1995;92:1148-1150.