Structure-activity studies of heparan mimetic polyanions for anti-prion therapies

Biochemical and Biophysical Research Communications

Volumn 363, Issue 1, 2007, Pages 95-100

  Ouidja, Mohand Ouidir ^a,b,c   Petit, Emmanuel ^d   Kerros, Marie Emmanuelle ^a,d   Ikeda, Yasunori ^a   Morin, Christophe ^a   Carpentier, Gilles ^a   Barritault, Denis ^a,d   Brugère Picoux, Jeanne ^c   Deslys, Jean Philippe ^b   Adjou, Karim ^b,c   Papy Garcia, Dulce ^a,d  

^a Université Paris 12 ^*  (France)

^b ECOLE NATIONALE VÉTÉRINAIRE D ALFORT   (France)

^c INSTITUT DE RADIOPROTECTION ET DE SÛRETÉ NUCLÉAIRE   (France)

^d OTR3 ^*  (France)

Author keywords

Anti prion; Heparan mimetic; Polyanion; Prion therapy; Rgta; Structure function

Indexed keywords

HEPARAN; HEPARIN; POLYANION; PRION PROTEIN;

ANIMAL CELL; ARTICLE; CARBOXYLATION; CONTROLLED STUDY; HYDROPHOBICITY; NONHUMAN; PRION DISEASE; PRIORITY JOURNAL; PROTEIN BINDING; STRUCTURE ACTIVITY RELATION; SULFATION;

ANIMALS; ANIONS; BINDING SITES; BIOMIMETIC MATERIALS; CELL LINE; HEPARITIN SULFATE; HUMANS; NEURONS; PRION DISEASES; PROTEIN BINDING; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 34548855942     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.08.113     Document Type: Article

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