-
1
-
-
33744460279
-
Proteomic libraries: Design, synthesis, and evaluation of p53-MDM2 interaction inhibitors
-
Lu, F. et al. Proteomic libraries: Design, synthesis, and evaluation of p53-MDM2 interaction inhibitors. J. Comb. Chem. 8 315-325 (2006).
-
(2006)
J. Comb. Chem
, vol.8
, pp. 315-325
-
-
Lu, F.1
-
2
-
-
33746735499
-
Hydrophobic effect and hydrogen bonds account for the improved activity of a complement inhibitor, compstatin
-
Katragadda, M., Magotti, P., Sfyroera, G. & Lambris, J.D. Hydrophobic effect and hydrogen bonds account for the improved activity of a complement inhibitor, compstatin. J. Med. Chem. 49, 4616-4622 (2006).
-
(2006)
J. Med. Chem
, vol.49
, pp. 4616-4622
-
-
Katragadda, M.1
Magotti, P.2
Sfyroera, G.3
Lambris, J.D.4
-
3
-
-
4143121255
-
Evaluation of fluorescence-based thermal shift assays for hit identification in drug discovery
-
Lo, M.C. et al. Evaluation of fluorescence-based thermal shift assays for hit identification in drug discovery. Anal. Biochem. 332, 153-159 (2004).
-
(2004)
Anal. Biochem
, vol.332
, pp. 153-159
-
-
Lo, M.C.1
-
4
-
-
33745902222
-
Analyzing ligand and small molecule binding activity of solubilized GPCRs using biosensor technology
-
Navratilova, I., Dioszegi, M. & Myszka, D.G. Analyzing ligand and small molecule binding activity of solubilized GPCRs using biosensor technology. Anal. Biochem. 355, 132-139 (2006).
-
(2006)
Anal. Biochem
, vol.355
, pp. 132-139
-
-
Navratilova, I.1
Dioszegi, M.2
Myszka, D.G.3
-
5
-
-
0036008098
-
Synthesis of calcineurin-resistant derivatives of FK506 and selection of compensatory receptors
-
Clemons, P.A. et al. Synthesis of calcineurin-resistant derivatives of FK506 and selection of compensatory receptors. Chem. Biol. 9, 49-61 (2002).
-
(2002)
Chem. Biol
, vol.9
, pp. 49-61
-
-
Clemons, P.A.1
-
6
-
-
33745295845
-
1 integrin for in vivo tumor imaging
-
1 integrin for in vivo tumor imaging. Nat. Chem. Biol. 2, 381-389 (2006).
-
(2006)
Nat. Chem. Biol
, vol.2
, pp. 381-389
-
-
Peng, L.1
-
7
-
-
33746099330
-
Biomolecular interaction analysis in functional proteomics
-
Moll, D. et al. Biomolecular interaction analysis in functional proteomics. J. Neural Transm. 113, 1015-1032 (2006).
-
(2006)
J. Neural Transm
, vol.113
, pp. 1015-1032
-
-
Moll, D.1
-
8
-
-
0033199751
-
Printing small molecules as microarrays and detecting protein-small molecule interactions en masse
-
MacBeath, G., Koehler, A.N. & Schreiber, S.L. Printing small molecules as microarrays and detecting protein-small molecule interactions en masse. J. Am. Chem. Soc. 121, 7967-7968 (1999).
-
(1999)
J. Am. Chem. Soc
, vol.121
, pp. 7967-7968
-
-
MacBeath, G.1
Koehler, A.N.2
Schreiber, S.L.3
-
9
-
-
0034674919
-
Small molecule microarrays: Covalent attachment and screening of alcohol-containing small molecules on glass slides
-
Hergenrother, P.J., Depew, K.M. & Schreiber, S.L. Small molecule microarrays: Covalent attachment and screening of alcohol-containing small molecules on glass slides. J. Am. Chem. Soc. 122, 7849-7850 (2000).
-
(2000)
J. Am. Chem. Soc
, vol.122
, pp. 7849-7850
-
-
Hergenrother, P.J.1
Depew, K.M.2
Schreiber, S.L.3
-
10
-
-
0038682103
-
Expanding the functional group compatibility of small-molecule microarrays: Discovery or novel calmodulin ligands
-
Barnes-Seeman, D., Park, S.B., Koehler, A.N. & Schreiber, S.L. Expanding the functional group compatibility of small-molecule microarrays: discovery or novel calmodulin ligands. Angew. Chem. Int. Ed. Engl. 42, 2376-2379 (2003).
-
(2003)
Angew. Chem. Int. Ed. Engl
, vol.42
, pp. 2376-2379
-
-
Barnes-Seeman, D.1
Park, S.B.2
Koehler, A.N.3
Schreiber, S.L.4
-
11
-
-
0036232915
-
Carbohydrate arrays for the evaluation of protein binding and enzymatic modification
-
Houseman, B.T. & Mrksich, M. Carbohydrate arrays for the evaluation of protein binding and enzymatic modification. Chem. Biol. 9, 443-454 (2002).
-
(2002)
Chem. Biol
, vol.9
, pp. 443-454
-
-
Houseman, B.T.1
Mrksich, M.2
-
12
-
-
0344667656
-
Immobilization of natural products on glass slides using a photoaffinity reaction and the detection of protein-small molecule interactions
-
Kanoh, N. et al. Immobilization of natural products on glass slides using a photoaffinity reaction and the detection of protein-small molecule interactions. Angew. Chem. Int. Ed. Engl. 42, 5584-5587 (2003).
-
(2003)
Angew. Chem. Int. Ed. Engl
, vol.42
, pp. 5584-5587
-
-
Kanoh, N.1
-
13
-
-
0348050489
-
Staudinger ligation: A new immobilization strategy for the preparation of small-molecule arrays
-
Kohn, M. et al. Staudinger ligation: A new immobilization strategy for the preparation of small-molecule arrays. Angew. Chem. Int. Ed. Engl. 42, 5830-5834 (2003).
-
(2003)
Angew. Chem. Int. Ed. Engl
, vol.42
, pp. 5830-5834
-
-
Kohn, M.1
-
14
-
-
9344225707
-
Microarrays of tagged combinatorial triazine libraries in the discovery of small molecule ligands of human IgG
-
Uttamchandani, M. et al. Microarrays of tagged combinatorial triazine libraries in the discovery of small molecule ligands of human IgG. J. Comb. Chem. 6, 862-868 (2004).
-
(2004)
J. Comb. Chem
, vol.6
, pp. 862-868
-
-
Uttamchandani, M.1
-
15
-
-
18844410861
-
Fabrication of chemical microarrays by efficient immobilization of hydrazide-linked substances on epoxide-coated glass surfaces
-
Lee, M.R. & Shin, I. Fabrication of chemical microarrays by efficient immobilization of hydrazide-linked substances on epoxide-coated glass surfaces. Angew. Chem. Int. Ed. Engl. 44, 2881-2884 (2005).
-
(2005)
Angew. Chem. Int. Ed. Engl
, vol.44
, pp. 2881-2884
-
-
Lee, M.R.1
Shin, I.2
-
16
-
-
33646587681
-
A robust small-molecule microarray platform for screening cell lysates
-
Bradner, J.E. et al. A robust small-molecule microarray platform for screening cell lysates. Chem. Biol. 13, 493-504 (2006).
-
(2006)
Chem. Biol
, vol.13
, pp. 493-504
-
-
Bradner, J.E.1
-
17
-
-
34548839470
-
-
National Research Council, The National Academies Press, Washington DC
-
National Research Council. Prudent Practices for Handling Hazardous Chemicals (The National Academies Press, Washington DC, 1995).
-
(1995)
Prudent Practices for Handling Hazardous Chemicals
-
-
-
18
-
-
0031683101
-
Synthesis and activity of bivalent FKBP12 ligands for the regulated dimerization of proteins
-
Keenan, T. et al. Synthesis and activity of bivalent FKBP12 ligands for the regulated dimerization of proteins. Bioorg. Med. Chem. 6, 1309-1335 (1998).
-
(1998)
Bioorg. Med. Chem
, vol.6
, pp. 1309-1335
-
-
Keenan, T.1
|