Biotransformation of 20(S)-protopanaxatriol by Mucor spinosus and the cytotoxic structure activity relationships of the transformed products

Phytochemistry

Volumn 68, Issue 20, 2007, Pages 2523-2530

  Zhang, Jie ^a   Guo, Hongzhu ^a,b   Tian, Yin ^a   Liu, Peng ^a   Li, Na ^b   Zhou, Jianping ^b   Guo, Dean ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b BEIJING INSTITUTE FOR DRUG CONTROL   (China)

Author keywords

20(S) Protopanaxatriol; Biotransformation; Cytotoxic activity; Mucor spinosus AS 3.3450

Indexed keywords

ANTINEOPLASTIC AGENT; PROTOPANAXATRIOL; SAPOGENIN; TRITERPENE; UNCLASSIFIED DRUG;

ARTICLE; BIOTRANSFORMATION; CELL SURVIVAL; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; HUMAN; IC 50; METABOLISM; MUCOR; STRUCTURE ACTIVITY RELATION; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; BIOTRANSFORMATION; CELL LINE, TUMOR; CELL SURVIVAL; HUMANS; INHIBITORY CONCENTRATION 50; MOLECULAR STRUCTURE; MUCOR; SAPOGENINS; STRUCTURE-ACTIVITY RELATIONSHIP; TRITERPENES;

FUNGI; MUCOR; MUCOR SPINOSUS;

EID: 34548838251     PISSN: 00319422     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phytochem.2007.05.028     Document Type: Article

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