Functions of prion protein PrPc;Fonctions de la protéine prion PrPc

Medecine/Sciences

Volumn 23, Issue 8-9, 2007, Pages 741-745

  Cazaubon, Sylvie ^a   Viegas, Pedro ^a   Couraud, Pierre Olivier ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

PRION PROTEIN;

APOPTOSIS; BRAIN DISEASE; CELL ACTIVATION; CELL DIFFERENTIATION; CREUTZFELDT JAKOB DISEASE; DEGENERATIVE DISEASE; DISEASE COURSE; EPITHELIUM CELL; HUMAN; IMMUNOCOMPETENT CELL; PRION DISEASE; PROTEIN FUNCTION; REVIEW;

BOVINAE; OVIS ARIES;

EID: 34548825402     PISSN: 07670974     EISSN: None     Source Type: Journal    
DOI: 10.1051/medsci/20072389741     Document Type: Review

References (30)

1. Prusiner SB. Novel proteinaceous infectious particles cause scrapie. Science 1982 ; 216 : 136-44.
2. Brown DR, Qin K, Herms JW, et al. The cellular prion protein binds copper in vivo. Nature 1997 ; 390 : 684-7.
3. Brown DR, Besinger A. Prion protein expression and superoxide dismutase activity. Biochem J 1998 ; 334 : 423-9.
4. Gaeta A, Hider RC. The crucial role of metal ions in neurodegeneration : the basis for a promising therapeutic strategy. Br J Pharmacol 2005 ; 146 : 1041-59.
5. Dupuis L, Loeffler JP. Protéine cellulaire du prion : au-delà des encéphalopathies spongiformes. Med Sci (Paris) 2003 ; 19 : 783-5.
6. Brown DR, Schulz-Schaeffer WJ, Schmidt B, Kretzschmar HA. Prion protein-deficient cells show altered response to oxidative stress due to decreased SOD-1 activity. Exp Neurol 1997 ; 146 : 104-12.
7. Schneider B, Mutel V, Pietri M, et al. NADPH oxidase and extracellular regulated kinases 1/2 are targets of prion protein signaling in neuronal and nonneuronal cells. Proc Natl Acad Sci USA 2003 ; 100 : 13326-31.
8. Mouillet-Richard S, Ermonval M, Chebassier C, et al. Signal transduction through prion protein. Science 2000 ; 289 : 1925-8.
9. Schneider B, Pietri M, Ermonval M, et al. Contrôler l'équilibre redox cellulaire : une fonction ubiquitaire pour la protéine prion cellulaire ? Med Sci (Paris) 2004 ; 20 : 21-3.
10. Kim BH, Lee HG, Choi JK, et al. The cellular prion protein (PrPC) prevents apoptotic neuronal cell death and mitochondrial dysfunction induced by serum deprivation. Brain Res Mol Brain Res 2004 ; 124 : 40-50.
11. Bounhar Y, Zhang Y, Goodyer CG, LeBlanc A. Prion protein protects human neurons against Bax-mediated apoptosis. J. Biol Chem 2001 ; 276 : 39145-9.
12. Saupe SJ, Supattapone S. What makes a good prion ? Conference on Prion Biology. EMBO Rep 2006 ; 7 : 254-8.
13. Zanata SM, Lopes MH, Mercadante AF, et al. Stress-inducible protein 1 is a cell surface ligand for cellular prion that triggers neuroprotection. EMBO J 2002 ; 21 : 3307-16.
14. Chiarini LB, Freitas AR, Zanata SM, et al. Cellular prion protein transduces neuroprotective signals. EMBO J 2002 ; 21 : 3317-26.
15. Solforosi L, Criado JR, McGavern DB, et al. Cross-linking cellular prion protein triggers neuronal apoptosis in vivo. Science 2004 ; 303 : 1514-6.
16. Paitel E, Sunyach C, Alves da Costa C, et al. Primary cultured neurons devoid of cellular prion display lower responsiveness to staurosporine through the control of p53 at both transcriptional and post-transcriptional levels. J Biol Chem 2004 ; 279 : 612-8.
17. Schmitt-Ulms G, Legname G, Baldwin MA, et al. Binding of neural cell adhesion molecules (N-CAMs) to the cellular prion protein. J Mol Biol 2001 ; 314 : 1209-25.
18. Rieger R, Edenhofer F, Lasmezas CI, Weiss S. The human 37-kDa laminin receptor precursor interacts with the prion protein in eukaryotic cells. Nat Med 1997 ; 3 : 1383-8.
19. Simoneau S, Haik S, Leucht C, et al. Different isoforms of the non-integrin laminin receptor are present in mouse brain and bind PrP. J Biol Chem 2003 ; 384 : 243-6.
20. Graner E, Mercadante AF, Zanata SM, et al. Cellular prion protein binds laminin and mediates neuritogenesis. Brain Res Mol Brain Res 2000 ; 76 : 85-92.
21. Graner E, Mercadante AF, Zanata SM, et al. Laminin-induced PC-12 cell differentiation is inhibited following laser inactivation of cellular prion protein. FEBS Lett 2000 ; 482 : 257-60.
22. Santuccione A, Sytnyk V, Leshchyns'ka I, Schachner M. Prion protein recruits its neuronal receptor NCAM to lipid rafts to activate p59fyn and to enhance neurite outgrowth. J Cell Biol 2005 ; 169 : 341-54.
23. Lopes MH, Hajj GN, Muras AG, et al. Interaction of cellular prion and stress-inducible protein 1 promotes neuritogenesis and neuroprotection by distinct signaling pathways. J Neurosci 2005 ; 25 : 11330-9.
24. Viegas P, Chaverot N, Enslen H, et al. Junctional expression of the prion protein PrPc by brain endothelial cells : a role in trans-endothelial migration of human monocytes. J Cell Sci 2006 ; 119 : 4634-43.
25. Knaus KJ, Morulas M, Swietnicki W, et al. Crystal structure of the human prion protein reveals a mechanism for oligomerization. Nat Struct Biol 2001 ; 8 : 770-4.
26. Morel E, Fouquet S, Chateau D, et al. The cellular prion protein PrPc is expressed in human enterocytes in cell-cell junctional domains. J Biol Chem 2004 ; 279 : 1499-505.
27. Li R, Liu D, Zanusso G, et al. The expression and potential function of cellular prion protein in human lymphocytes. Cell Immunol 2001 ; 207 : 49-58.
28. Hugel B, Martinez MC, Kunzelmann C, et al. Modulation of signal transduction through the cellular prion protein is linked to its incorporation in lipid rafts. Cell Life Mol Sci 2004 ; 61 : 2998-3007.
29. Stuermer CA, Langhorst MF, Wiechers MF, et al. PrPc capping in T cells promotes its association with the lipid raft proteins reggie-1 and reggie-2 and leads to signal transduction. FASEB J 2004 ; 18 : 1731-3.
30. Ballerini C, Gourdain P, Bachy V, et al. Functional implication of cellular prion protein in antigen-driven interactions between T cells and dendritic cells. J Immunol 2006 ; 176 : 7254-62.