Cellular prion protein: More than what beyond spongiform encephalopathies;Protéine cellulaire du prion: Au-delà des encéphalopathies spongiformes

Medecine/Sciences

Volumn 19, Issue 8-9, 2003, Pages 783-785

  Dupuis, Luc ^a   Loeffler, Jean Philippe ^a  

^a UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; SUPEROXIDE DISMUTASE;

ALZHEIMER DISEASE; AMYOTROPHIC LATERAL SCLEROSIS; BRAIN SPONGIOSIS; DENERVATION; DISEASE ASSOCIATION; HUMAN; INCLUSION BODY MYOSITIS; NERVE DEGENERATION; NOTE; PARKINSON DISEASE; POLYMYOSITIS; PRION; PROTEIN EXPRESSION; SCRAPIE;

EID: 0141428803     PISSN: 07670974     EISSN: None     Source Type: Journal    
DOI: 10.1051/medsci/20031989783     Document Type: Note

References (18)

1. Bueler H, Fischer M, Long Y, et al. Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein. Nature 1992; 356: 577-82.
2. Prusiner SB, Scott MR, De Armond SJ, Cohen FE. Prion protein biology. Cell 1998; 93: 337-48.
3. Kovacs G, Zerbi P, Voigtlander T, et al. The prion protein in human neurodegenerative disorders. Neurosci Lett 2002; 329: 269.
4. Ferrer I, Blanco R, Carmona M, et al. Prion protein expression in senile plaques in Alzheimer's disease. Acta Neuropathol (Berl) 2001; 101: 49-56.
5. Herms J, Tings T, Gall S, et al. Evidence of presynaptic location and function of the prion protein. J Neurosci 1999; 19: 8866-75.
6. Brown DR, Qin K, Herms JW, et al. The cellular prion protein binds copper in vivo. Nature 1997; 390: 684-7.
7. Brown DR. Prion and prejudice: normal protein and the synapse. Trends Neurosci 2001; 24: 85-90.
8. Mouillet-Richard S, Ermonval M, Chebassier C, et al. Signal transduction through prion protein. Science 2000; 289: 1925-8
9. Kuwahara C, Takeuchi AM, Nishimura T, et al. Prions prevent neuronal cell-line death. Nature 1999; 400: 225-6.
10. Bounhar Y, Zhang Y, Goodyer CG, LeBlanc A. Prion protein protects human neurons against Bax-mediated apoptosis. J Biol Chem 2001; 276: 39145-9.
11. Paitel E, Fahraeus R, Checler F. Cellular prion protein sensitizes neurons to apoptotic stimuli through Mdm2-regulated and P53-dependent caspase 3-like activation. J Biol Chem 2003; 278: 10061-6.
12. Dupuis L, Mbebi C, Gonzalez de Aguilar JL, et al. Loss of prion protein in a transgenic model of amyotrophic lateral sclerosis. Mol Cell Neurosci 2002; 19: 216-24.
13. Dupuis L, Di Scala F, Gonzalez de Aguilar JL, Rene F, De Tapia M, Loeffler JP. Denervation is not the primary cause of prion protein downregulation occuring in the spinal cord of a transgenic model of amyotrophic lateral sclerosis. Ann NY Acad Sci 2002; 973: 116-9.
14. Zanusso G, Vattemi G, Ferrari S, et al. Increased expression of the normal cellular isoform of prion protein in inclusion-body myositis, inflammatory myopathies and denervation atrophy. Brain Pathol 2001; 11: 182-9.
15. Lampe JB, Walter MC, Reichmann H. Neurodegeneration-associated proteins and inflammation in sporadic inclusion-body myositis. Adv Exp Med Biol 2001; 487: 219-28.
16. Westaway D, DeArmond SJ, Cayetano-Canlas J, et al. Degeneration of skeletal muscle, peripheral nerves, and the central nervous system in transgenic mice overexpressing wild-type prion proteins. Cell 1994; 76: 117-29.
17. Chiesa R, Pestronk A, Schmidt RE, et al. Primary myopathy and accumulation of PrPSc-like molecules in peripheral tissues of transgenic mice expressing a prion protein insertional mutation. Neurobiol Dis 2001; 8: 279-88.
18. Miele G, Jeffrey M, Turnbull D, Manson J, Clinton, M. Ablation of cellular prion protein expression affects mitochondrial numbers and morphology. Biochem Biophys Res Commun 2002; 291: 372-7.