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Volumn 7, Issue 9, 2007, Pages 1157-1163

Symptomatic treatment of multiple sclerosis using cannabinoids: Recent advances

Author keywords

Cannabinoids; Multiple sclerosis; Pain; Spasticity

Indexed keywords

CANNABINOID DERIVATIVE; CANNABIS; DRONABINOL; NABILONE; TETRAHYDROCANNABINOL;

EID: 34548821248     PISSN: 14737175     EISSN: 17448360     Source Type: Journal    
DOI: 10.1586/14737175.7.9.1157     Document Type: Review
Times cited : (22)

References (64)
  • 1
    • 0030740514 scopus 로고    scopus 로고
    • The perceived effects of smoked cannabis on patients with multiple sclerosis
    • Consroe P, Musty R, Rein J et al. The perceived effects of smoked cannabis on patients with multiple sclerosis. Eur. Neurol. 38, 44-48 (1997).
    • (1997) Eur. Neurol , vol.38 , pp. 44-48
    • Consroe, P.1    Musty, R.2    Rein, J.3
  • 2
    • 18044381739 scopus 로고    scopus 로고
    • Cannabis use in HIV for pain and other medical symptoms
    • Woolridge E, Barton S, Samuel J et al. Cannabis use in HIV for pain and other medical symptoms. J. Pain Symptom Manage. 29, 358-368 (2005).
    • (2005) J. Pain Symptom Manage , vol.29 , pp. 358-368
    • Woolridge, E.1    Barton, S.2    Samuel, J.3
  • 3
    • 5044251807 scopus 로고    scopus 로고
    • Smith PF. Sativex® (GW-1000). Curr. Opin. Investig. Drugs 5, 748-754 (2004).
    • Smith PF. Sativex® (GW-1000). Curr. Opin. Investig. Drugs 5, 748-754 (2004).
  • 5
    • 0035150352 scopus 로고    scopus 로고
    • Cannabinoid receptors and pain
    • Pertwee RG. Cannabinoid receptors and pain. Prog. Neurobiol. 63, 569-611 (2001).
    • (2001) Prog. Neurobiol , vol.63 , pp. 569-611
    • Pertwee, R.G.1
  • 6
    • 0036606619 scopus 로고    scopus 로고
    • Retrograde signalling by endocannabinoids
    • Kreitzer AC, Regehr WG. Retrograde signalling by endocannabinoids. Curr. Opin. Neurobiol. 12, 324-330 (2002).
    • (2002) Curr. Opin. Neurobiol , vol.12 , pp. 324-330
    • Kreitzer, A.C.1    Regehr, W.G.2
  • 7
    • 0036867665 scopus 로고    scopus 로고
    • Retrograde signalling in the regulation of synaptic transmission: Focus on endocannabinoids
    • Alger BE. Retrograde signalling in the regulation of synaptic transmission: focus on endocannabinoids. Prog. Neurobiol. 68, 247-286 (2002).
    • (2002) Prog. Neurobiol , vol.68 , pp. 247-286
    • Alger, B.E.1
  • 8
    • 34248219556 scopus 로고    scopus 로고
    • Cannabinoids for the treatment of inflammation
    • Summarizes and evaluates the most recent evidence relating to cannabinoid (CB)2 receptors and inflammation, ••
    • Ashton JC. Cannabinoids for the treatment of inflammation. Curr. Opin. Invest. Drugs 8, 373-384 (2007). •• Summarizes and evaluates the most recent evidence relating to cannabinoid (CB)2 receptors and inflammation.
    • (2007) Curr. Opin. Invest. Drugs , vol.8 , pp. 373-384
    • Ashton, J.C.1
  • 9
    • 29544446576 scopus 로고    scopus 로고
    • The endocannabinoid anandamide protects neurons during CNS inflammation by induction of MKP-1 in microglial cells
    • Eljasschewitsch E, Witting A, Mawrin C et al. The endocannabinoid anandamide protects neurons during CNS inflammation by induction of MKP-1 in microglial cells. Neuron 49, 67-79 (2006).
    • (2006) Neuron , vol.49 , pp. 67-79
    • Eljasschewitsch, E.1    Witting, A.2    Mawrin, C.3
  • 10
    • 0033992335 scopus 로고    scopus 로고
    • Dexanabinol (HU-211) effect on experimental autoimmune encephalomyelitis: Implications for the treatment of acute relapses of multiple sclerosis
    • Achiron A, Miron S, Lavie V et al. Dexanabinol (HU-211) effect on experimental autoimmune encephalomyelitis: implications for the treatment of acute relapses of multiple sclerosis. J. Neuroimmunol. 102, 26-31 (2000).
    • (2000) J. Neuroimmunol , vol.102 , pp. 26-31
    • Achiron, A.1    Miron, S.2    Lavie, V.3
  • 11
    • 0035256557 scopus 로고    scopus 로고
    • Endocannabinoids control spasticity in a multiple sclerosis model
    • Baker D, Pryce G, Croxford JL et al. Endocannabinoids control spasticity in a multiple sclerosis model. FASEB J. 15, 300-302 (2001).
    • (2001) FASEB J , vol.15 , pp. 300-302
    • Baker, D.1    Pryce, G.2    Croxford, J.L.3
  • 12
    • 0034594905 scopus 로고    scopus 로고
    • Cannabinoids control spasticity and tremor in a multiple sclerosis model
    • Baker D, Pryce G, Croxford JL et al. Cannabinoids control spasticity and tremor in a multiple sclerosis model. Nature 404, 84-87 (2000).
    • (2000) Nature , vol.404 , pp. 84-87
    • Baker, D.1    Pryce, G.2    Croxford, J.L.3
  • 13
    • 0035452419 scopus 로고    scopus 로고
    • Changes in cannabinoid (CB1) receptors in striatal and cortical regions of rats with experimental allergic encephalomyelitis, an animal model of multiple sclerosis
    • Berrendero F, Sanchez A, Cabranes A et al. Changes in cannabinoid (CB1) receptors in striatal and cortical regions of rats with experimental allergic encephalomyelitis, an animal model of multiple sclerosis. Synapse 41, 195-202 (2001).
    • (2001) Synapse , vol.41 , pp. 195-202
    • Berrendero, F.1    Sanchez, A.2    Cabranes, A.3
  • 14
    • 33847420442 scopus 로고    scopus 로고
    • Cannabinoid CB1 and CB2 receptors and fatty acid amide hydrolase are aare specific markers of plaque cell subtypes in human multiple sclerosis
    • Benito C, Romero JP, Tolon RM et al. Cannabinoid CB1 and CB2 receptors and fatty acid amide hydrolase are aare specific markers of plaque cell subtypes in human multiple sclerosis. J. Neurosci. 27(9), 2396-2402 (2007).
    • (2007) J. Neurosci , vol.27 , Issue.9 , pp. 2396-2402
    • Benito, C.1    Romero, J.P.2    Tolon, R.M.3
  • 15
    • 0035822343 scopus 로고    scopus 로고
    • Are cannabinoids an effective and safe treatment option in the management of pain? A qualitative systematic review
    • Campbell FA, Tramer MR, Carroll et al. Are cannabinoids an effective and safe treatment option in the management of pain? A qualitative systematic review. Br. Med. J. 323, 13-16 (2001).
    • (2001) Br. Med. J , vol.323 , pp. 13-16
    • Campbell, F.A.1    Tramer, M.R.2    Carroll3
  • 16
    • 0035822323 scopus 로고    scopus 로고
    • Cannabinoids for control of chemotherapy-induced nausea and vomiting: Quantitative systematic review
    • Tramer MR, Caroll D, Campbell FA et al. Cannabinoids for control of chemotherapy-induced nausea and vomiting: quantitative systematic review. Br. Med. J. 323, 16-21 (2001).
    • (2001) Br. Med. J , vol.323 , pp. 16-21
    • Tramer, M.R.1    Caroll, D.2    Campbell, F.A.3
  • 17
    • 2342613658 scopus 로고    scopus 로고
    • Initial experiences with medicinal extracts of cannabis for chronic pain: Results from 34 'N of 1' studies
    • Notcutt W, Price M, Miller R et al. Initial experiences with medicinal extracts of cannabis for chronic pain: results from 34 'N of 1' studies. Anaesthesia 59, 440-452 (2004).
    • (2004) Anaesthesia , vol.59 , pp. 440-452
    • Notcutt, W.1    Price, M.2    Miller, R.3
  • 18
    • 0142227167 scopus 로고    scopus 로고
    • Lack of analgesic efficacy of oral Δ-9-tetrahydrocannabinol in post-operative pain
    • Example of a negative effect of a cannabinoid on pain, •
    • Buggy DJ, Toogood L, Maric S et al. Lack of analgesic efficacy of oral Δ-9-tetrahydrocannabinol in post-operative pain. Pain 106,169-172 (2003). • Example of a negative effect of a cannabinoid on pain.
    • (2003) Pain , vol.106 , pp. 169-172
    • Buggy, D.J.1    Toogood, L.2    Maric, S.3
  • 19
    • 1542284124 scopus 로고    scopus 로고
    • Are oral cannabinoids safe and effective in refractory neuropathic pain?
    • Example of a negative effect of a cannabinoid on pain, •
    • Attal N, Brasseur L, Guirimand D et al. Are oral cannabinoids safe and effective in refractory neuropathic pain? Eur. J. Pain 8,173-177 (2004). • Example of a negative effect of a cannabinoid on pain.
    • (2004) Eur. J. Pain , vol.8 , pp. 173-177
    • Attal, N.1    Brasseur, L.2    Guirimand, D.3
  • 20
    • 0141515748 scopus 로고    scopus 로고
    • The analgesic effect or oral Δ-9-tetrahydrocannabinol (THC), morphine and a THC and morphine combination in healthy subjects under experimental pain conditions
    • Example of a negative effect of a cannabinoid on pain, •
    • Naef M, Curatolo M, Petersen-Felix S et al. The analgesic effect or oral Δ-9-tetrahydrocannabinol (THC), morphine and a THC and morphine combination in healthy subjects under experimental pain conditions. Pain 105, 79-88 (2003). • Example of a negative effect of a cannabinoid on pain.
    • (2003) Pain , vol.105 , pp. 79-88
    • Naef, M.1    Curatolo, M.2    Petersen-Felix, S.3
  • 21
    • 0037076468 scopus 로고    scopus 로고
    • Safety, tolerability and efficacy of orally administered cannabinoids in MS
    • Killestein J, Hoogervorst ELJ, Reif M et al. Safety, tolerability and efficacy of orally administered cannabinoids in MS. Neurology 58, 1404-1407 (2002).
    • (2002) Neurology , vol.58 , pp. 1404-1407
    • Killestein, J.1    Hoogervorst, E.L.J.2    Reif, M.3
  • 22
    • 0242654882 scopus 로고    scopus 로고
    • Cannabinoids for the treatment of spasticity and other symptoms related to multiple sclerosis (CAMS study): Multicentre, randomised placebo-controlled trial
    • Zajicek J, Fox P, Sanders H et al. Cannabinoids for the treatment of spasticity and other symptoms related to multiple sclerosis (CAMS study): multicentre, randomised placebo-controlled trial. Lancet 362, 1517-1526 (2003).
    • (2003) Lancet , vol.362 , pp. 1517-1526
    • Zajicek, J.1    Fox, P.2    Sanders, H.3
  • 23
    • 28144454955 scopus 로고    scopus 로고
    • Zajicek JP, Sanders HP, Wright DE et al. Cannabinoids in multiple sclerosis (CAMS) study: safety and efficacy data for 12 months follow-up. J. Neurol. Neurosurg. Psychiatr. 76, 1664-1669 (2005). •• Follow-up study of the Cannabinoids in Multiple Sclerosis (CAMS) trial.
    • Zajicek JP, Sanders HP, Wright DE et al. Cannabinoids in multiple sclerosis (CAMS) study: safety and efficacy data for 12 months follow-up. J. Neurol. Neurosurg. Psychiatr. 76, 1664-1669 (2005). •• Follow-up study of the Cannabinoids in Multiple Sclerosis (CAMS) trial.
  • 24
    • 4043096916 scopus 로고    scopus 로고
    • Does the cannabinoid dronabinol reduce central pain in multiple sclerosis? Randomised double-blind placebo controlled crossover trial
    • Svendsen KB, Jensen TS, Bach FW. Does the cannabinoid dronabinol reduce central pain in multiple sclerosis? Randomised double-blind placebo controlled crossover trial. Br. Med. J. 329, 253-261 (2004).
    • (2004) Br. Med. J , vol.329 , pp. 253-261
    • Svendsen, K.B.1    Jensen, T.S.2    Bach, F.W.3
  • 25
    • 0345669751 scopus 로고    scopus 로고
    • A preliminary controlled study to determine whether whole-plant cannabis extracts can improve intractable neurogenic symptoms
    • Wade DT, Robson P, House H et al. A preliminary controlled study to determine whether whole-plant cannabis extracts can improve intractable neurogenic symptoms. Clin. Rehabil. 17, 21-29 (2003).
    • (2003) Clin. Rehabil , vol.17 , pp. 21-29
    • Wade, D.T.1    Robson, P.2    House, H.3
  • 26
    • 4344582253 scopus 로고    scopus 로고
    • Do cannabis-based medicinal extracts have general or specific effects on symptoms in multiple sclerosis? A double-blind, randomized, placebo-controlled study on 160 patients
    • Wade DT, Makela P, Robson P et al. Do cannabis-based medicinal extracts have general or specific effects on symptoms in multiple sclerosis? A double-blind, randomized, placebo-controlled study on 160 patients. Mult. Scler. 10, 434-441 (2004).
    • (2004) Mult. Scler , vol.10 , pp. 434-441
    • Wade, D.T.1    Makela, P.2    Robson, P.3
  • 27
    • 4344571664 scopus 로고    scopus 로고
    • Efficacy, safety and tolerability of an orally administered cannabis extract in the treatment of spasticity in patients with multiple sclerosis: A randomized, double-blind, placebo-controlled, crossover study
    • Vaney C, Heinzel-Gutenbrunner M, Jobin P et al. Efficacy, safety and tolerability of an orally administered cannabis extract in the treatment of spasticity in patients with multiple sclerosis: a randomized, double-blind, placebo-controlled, crossover study. Mult. Scler. 10, 417-424 (2004).
    • (2004) Mult. Scler , vol.10 , pp. 417-424
    • Vaney, C.1    Heinzel-Gutenbrunner, M.2    Jobin, P.3
  • 28
    • 25444530723 scopus 로고    scopus 로고
    • Randomized, controlled trial of cannabis-based medicine in central pain in multiple sclerosis
    • One of the most recent clinical trials of cannabinoid in multiple sclerosis MS, ••
    • Rog DJ, Nurmikko TJ, Friede T et al. Randomized, controlled trial of cannabis-based medicine in central pain in multiple sclerosis. Neurology 65, 812-819 (2005). •• One of the most recent clinical trials of cannabinoid in multiple sclerosis (MS).
    • (2005) Neurology , vol.65 , pp. 812-819
    • Rog, D.J.1    Nurmikko, T.J.2    Friede, T.3
  • 29
    • 29844435136 scopus 로고    scopus 로고
    • Preliminary assessment of the efficacy, tolerability and safety of a cannabis-based medicine (Sativex®) in the treatment of pain caused by rheumatoid arthritis
    • •• Recently published study of the effects of cannabinoid on rheumatoid arthritis-related pain
    • Blake DR, Robson P, Ho M et al. Preliminary assessment of the efficacy, tolerability and safety of a cannabis-based medicine (Sativex®) in the treatment of pain caused by rheumatoid arthritis. Rheumatology 45, 50-52 (2006). •• Recently published study of the effects of cannabinoid on rheumatoid arthritis-related pain.
    • (2006) Rheumatology , vol.45 , pp. 50-52
    • Blake, D.R.1    Robson, P.2    Ho, M.3
  • 30
    • 33745025055 scopus 로고    scopus 로고
    • Long-term use of a cannabis-based medicine in the treatment of spasticity and other symptoms in multiple sclerosis
    • Wade DT, Makela PM, House H et al. Long-term use of a cannabis-based medicine in the treatment of spasticity and other symptoms in multiple sclerosis. Mult. Scler. 12, 639-645 (2006).
    • (2006) Mult. Scler , vol.12 , pp. 639-645
    • Wade, D.T.1    Makela, P.M.2    House, H.3
  • 31
    • 33847766180 scopus 로고    scopus 로고
    • Sativex Spasticity in MS Study Group. Randomized controlled trial of cannabis-based medicine in spasticity caused by multiple sclerosis
    • Recent report of the long-term effects of Cannabis-based medicines, ••
    • Colin C, Davies P, Mutiboko IK et al. Sativex Spasticity in MS Study Group. Randomized controlled trial of cannabis-based medicine in spasticity caused by multiple sclerosis. Eur. J. Neurol. 14, 290-296 (2007). •• Recent report of the long-term effects of Cannabis-based medicines.
    • (2007) Eur. J. Neurol , vol.14 , pp. 290-296
    • Colin, C.1    Davies, P.2    Mutiboko, I.K.3
  • 32
    • 1842580669 scopus 로고    scopus 로고
    • The effects of cannabis on tremor in patients with multiple sclerosis
    • Fox P, Bain PG, Glickman S et al. The effects of cannabis on tremor in patients with multiple sclerosis. Neurology 62, 1105-1109 (2004).
    • (2004) Neurology , vol.62 , pp. 1105-1109
    • Fox, P.1    Bain, P.G.2    Glickman, S.3
  • 33
    • 33646769573 scopus 로고    scopus 로고
    • Holdcroft A, Maze M, Dore C et al. A multicenter dose-escalation study of the analgesic and adverse effects of an oral cannabis extract (Cannador) for post-operative pain management. Anesthesiology 104, 1040-1046 (2006). • Recent study of the effects of a Cannabis extract on postoperative pain.
    • Holdcroft A, Maze M, Dore C et al. A multicenter dose-escalation study of the analgesic and adverse effects of an oral cannabis extract (Cannador) for post-operative pain management. Anesthesiology 104, 1040-1046 (2006). • Recent study of the effects of a Cannabis extract on postoperative pain.
  • 34
    • 33847013770 scopus 로고    scopus 로고
    • Abrams DI, Jay CA, Shade SB et al. Cannabis in painful HIV-associated sensory neuropathy. Neurology 68, 515-521 (2007). •• Study of the effects of smoking Cannabis on pain related to HIV.
    • Abrams DI, Jay CA, Shade SB et al. Cannabis in painful HIV-associated sensory neuropathy. Neurology 68, 515-521 (2007). •• Study of the effects of smoking Cannabis on pain related to HIV.
  • 35
    • 0141593561 scopus 로고    scopus 로고
    • Analgesic effect of the synthetic cannabinoid CT-3 on chronic neuropathic pain. A randomized controlled study
    • Kaarst M, Salim K, Burtsein S et al. Analgesic effect of the synthetic cannabinoid CT-3 on chronic neuropathic pain. A randomized controlled study. JAMA 290, 1757-1762 (2003).
    • (2003) JAMA , vol.290 , pp. 1757-1762
    • Kaarst, M.1    Salim, K.2    Burtsein, S.3
  • 36
    • 33750618230 scopus 로고    scopus 로고
    • Low dose treatment with the synthetic cannabinoid Nabilone significantly reduces spasticity-related pain
    • Wissel J, Haydn T, Muller J et al. Low dose treatment with the synthetic cannabinoid Nabilone significantly reduces spasticity-related pain. J. Neurol. 253, 1337-1341 (2006).
    • (2006) J. Neurol , vol.253 , pp. 1337-1341
    • Wissel, J.1    Haydn, T.2    Muller, J.3
  • 37
    • 4344585483 scopus 로고    scopus 로고
    • An open-label pilot study of cannabis based extracts for bladder dysfunction in advanced multiple sclerosis
    • Brady CM, DasGupta R, Dalton C et al. An open-label pilot study of cannabis based extracts for bladder dysfunction in advanced multiple sclerosis. Mult. Scler. 10, 425-433 (2004).
    • (2004) Mult. Scler , vol.10 , pp. 425-433
    • Brady, C.M.1    DasGupta, R.2    Dalton, C.3
  • 38
    • 33750037938 scopus 로고    scopus 로고
    • The effect of cannabis on urge incontinence in patients with multiple sclerosis: A multicentre, randomised placebo-controlled trial (CAMS-LUTS)
    • Freeman RM, Adekanmi O, Waterfield MR et al. The effect of cannabis on urge incontinence in patients with multiple sclerosis: a multicentre, randomised placebo-controlled trial (CAMS-LUTS). Int. Urogynecol. J. Pelvic Floor Dysfunct. 17, 636-641 (2006).
    • (2006) Int. Urogynecol. J. Pelvic Floor Dysfunct , vol.17 , pp. 636-641
    • Freeman, R.M.1    Adekanmi, O.2    Waterfield, M.R.3
  • 39
    • 4344599087 scopus 로고    scopus 로고
    • The therapeutic value of cannabinoids in MS: Real or imaginary?
    • Killestein J, Polman C. The therapeutic value of cannabinoids in MS: real or imaginary? Mult. Scler. 10, 339-340 (2004).
    • (2004) Mult. Scler , vol.10 , pp. 339-340
    • Killestein, J.1    Polman, C.2
  • 40
    • 0034565244 scopus 로고    scopus 로고
    • Shakespeare DT, Boggild M, Young C. Anti-spasticity agents for multiple sclerosis. Cochrane Database Syst. Rev. 4, CD001332 (2000).
    • Shakespeare DT, Boggild M, Young C. Anti-spasticity agents for multiple sclerosis. Cochrane Database Syst. Rev. 4, CD001332 (2000).
  • 41
    • 0032527129 scopus 로고    scopus 로고
    • Hippocampal neurotoxicity of Δ-9-tetrhydrocannabinol
    • Chan GCK, Hinde TR, Impey S et al. Hippocampal neurotoxicity of Δ-9-tetrhydrocannabinol. J. Neurosci. 18, 5322-5332 (1998).
    • (1998) J. Neurosci , vol.18 , pp. 5322-5332
    • Chan, G.C.K.1    Hinde, T.R.2    Impey, S.3
  • 42
    • 0033561159 scopus 로고    scopus 로고
    • Cannabinoids and neuroprotection in global and focal cerebral ischemia and in neuronal cultures
    • Nagayama T, Sinor AD, Chen J et al. Cannabinoids and neuroprotection in global and focal cerebral ischemia and in neuronal cultures. J. Neurosci. 19, 2987-2995 (1999).
    • (1999) J. Neurosci , vol.19 , pp. 2987-2995
    • Nagayama, T.1    Sinor, A.D.2    Chen, J.3
  • 43
    • 0036074054 scopus 로고    scopus 로고
    • Δ-9- tetrahydrocannabinol-induced apoptosis in the thymus and spleen as a mechanism of immunosuppression in vitro and in vivo
    • McKallip RJ, Lombard C, Fisher M et al. Δ-9- tetrahydrocannabinol-induced apoptosis in the thymus and spleen as a mechanism of immunosuppression in vitro and in vivo. J. Pharmacol. Exp. Therap. 302, 451-465 (2002).
    • (2002) J. Pharmacol. Exp. Therap , vol.302 , pp. 451-465
    • McKallip, R.J.1    Lombard, C.2    Fisher, M.3
  • 44
    • 8444244202 scopus 로고    scopus 로고
    • Effect of cannabinoid ingestion (in the form of bhang) on the immune system of high school and university students
    • El-Gohary M, Eid MA. Effect of cannabinoid ingestion (in the form of bhang) on the immune system of high school and university students. Hum. Exp. Toxicol. 23, 149-156 (2004).
    • (2004) Hum. Exp. Toxicol , vol.23 , pp. 149-156
    • El-Gohary, M.1    Eid, M.A.2
  • 45
    • 0141677644 scopus 로고    scopus 로고
    • Short-term effects of cannabinoids in patients with HIV-1 infection
    • Abrams DI, Hilton JF, Leiser RJ et al. Short-term effects of cannabinoids in patients with HIV-1 infection. Ann. Intern. Med. 139, 258-266 (2003).
    • (2003) Ann. Intern. Med , vol.139 , pp. 258-266
    • Abrams, D.I.1    Hilton, J.F.2    Leiser, R.J.3
  • 46
    • 8544278893 scopus 로고    scopus 로고
    • Long-term efficacy and safety of dronabinol for acquired immunodeficiency syndrome associated anorexia
    • Beal JE, Olson R, Lefkowitz L et al. Long-term efficacy and safety of dronabinol for acquired immunodeficiency syndrome associated anorexia. J. Pain Symptom Manage. 14, 7-14 (1997).
    • (1997) J. Pain Symptom Manage , vol.14 , pp. 7-14
    • Beal, J.E.1    Olson, R.2    Lefkowitz, L.3
  • 47
    • 0034792274 scopus 로고    scopus 로고
    • Neuropsychological performance in long-term cannabis users
    • Pope HG, Gruber AJ, Hudson JI et al. Neuropsychological performance in long-term cannabis users. Arch. Gen. Psychiat. 58, 909-915 (2001).
    • (2001) Arch. Gen. Psychiat , vol.58 , pp. 909-915
    • Pope, H.G.1    Gruber, A.J.2    Hudson, J.I.3
  • 49
    • 33645106228 scopus 로고    scopus 로고
    • Long-term effects of frequent cannabis use on working memory and attention: An fMRI study
    • Jager G, Kahn RS, Van Den Brink W et al. Long-term effects of frequent cannabis use on working memory and attention: an fMRI study. Psychopharmacol. (Berl.) 185, 358-368 (2006).
    • (2006) Psychopharmacol. (Berl.) , vol.185 , pp. 358-368
    • Jager, G.1    Kahn, R.S.2    Van Den Brink, W.3
  • 50
    • 0034768549 scopus 로고    scopus 로고
    • Differential effects on facets of attention in adolescents prenatally exposed to cigarettes and marihuana
    • Fried PA, Watksinson B. Differential effects on facets of attention in adolescents prenatally exposed to cigarettes and marihuana. Neurotoxicol. Teratol. 23, 421-430 (2001).
    • (2001) Neurotoxicol. Teratol , vol.23 , pp. 421-430
    • Fried, P.A.1    Watksinson, B.2
  • 51
    • 0035077403 scopus 로고    scopus 로고
    • A literature review of the consequences of prenatal marihuana exposure. An emerging theme of a deficiency in aspects of executive function
    • Fried PA, Smith AM. A literature review of the consequences of prenatal marihuana exposure. An emerging theme of a deficiency in aspects of executive function. Neurotoxicol. Teratol. 23, 1-11 (2001).
    • (2001) Neurotoxicol. Teratol , vol.23 , pp. 1-11
    • Fried, P.A.1    Smith, A.M.2
  • 52
    • 0038120885 scopus 로고    scopus 로고
    • Differential effects on cognitive functioning in 13- to 16 year-olds prenatally exposed to cigarettes and marihuana
    • Fried PA, Watkinson B, Gray R. Differential effects on cognitive functioning in 13- to 16 year-olds prenatally exposed to cigarettes and marihuana. Neurotoxicol. Teratol. 25, 427-436 (2003).
    • (2003) Neurotoxicol. Teratol , vol.25 , pp. 427-436
    • Fried, P.A.1    Watkinson, B.2    Gray, R.3
  • 53
    • 2942556797 scopus 로고    scopus 로고
    • Prenatal marijuana and alcohol exposure and academic achievement at age 10
    • Goldschmidt L, Richardson GA, Cornelius MD et al. Prenatal marijuana and alcohol exposure and academic achievement at age 10. Neurotoxicol. Teratol. 26, 521-532 (2004).
    • (2004) Neurotoxicol. Teratol , vol.26 , pp. 521-532
    • Goldschmidt, L.1    Richardson, G.A.2    Cornelius, M.D.3
  • 54
    • 0034611981 scopus 로고    scopus 로고
    • Effects of prenatal marijuana exposure on child behavior problems at age 10
    • Goldschmidt L, Day NL, Richardson GA. Effects of prenatal marijuana exposure on child behavior problems at age 10. Neurotoxicol. Teratol. 22, 325-336 (2000).
    • (2000) Neurotoxicol. Teratol , vol.22 , pp. 325-336
    • Goldschmidt, L.1    Day, N.L.2    Richardson, G.A.3
  • 55
    • 2942528872 scopus 로고    scopus 로고
    • Effects of prenatal marijuana on response inhibition: An fMRI study of young adults
    • Smith AM, Fried PA, Hogan MJ et al. Effects of prenatal marijuana on response inhibition: an fMRI study of young adults. Neurotoxicol. Teratol. 26, 533-542 (2004).
    • (2004) Neurotoxicol. Teratol , vol.26 , pp. 533-542
    • Smith, A.M.1    Fried, P.A.2    Hogan, M.J.3
  • 56
    • 34347234817 scopus 로고    scopus 로고
    • The temporal dynamics of relationships between cannabis, psychosis and depression among young adults with psychotic disorders: Findings from a 10 month prospective study
    • One of the most recent studies of the potential link between Cannabis use and psychosis, ••
    • Degenhardt L, Tennant C, Gilmour S et al. The temporal dynamics of relationships between cannabis, psychosis and depression among young adults with psychotic disorders: findings from a 10 month prospective study. Psychol. Med. 37(7), 927-934 (2007). •• One of the most recent studies of the potential link between Cannabis use and psychosis.
    • (2007) Psychol. Med , vol.37 , Issue.7 , pp. 927-934
    • Degenhardt, L.1    Tennant, C.2    Gilmour, S.3
  • 57
    • 14944386553 scopus 로고    scopus 로고
    • Tests of causal linkages between cannabis use and psychotic symptoms
    • Fergusson DM, Horwood J, Ridder EM. Tests of causal linkages between cannabis use and psychotic symptoms. Addiction 100, 354-366 (2005).
    • (2005) Addiction , vol.100 , pp. 354-366
    • Fergusson, D.M.1    Horwood, J.2    Ridder, E.M.3
  • 58
    • 11244260452 scopus 로고    scopus 로고
    • Prospective cohort study of cannabis use, predisposition for psychosis and psychotic symptoms in young people
    • Henquet C, Krabbendam L, Spauwen J et al. Prospective cohort study of cannabis use, predisposition for psychosis and psychotic symptoms in young people. Br. Med. J. 330, 11-16 (2005).
    • (2005) Br. Med. J , vol.330 , pp. 11-16
    • Henquet, C.1    Krabbendam, L.2    Spauwen, J.3
  • 59
    • 34147150114 scopus 로고    scopus 로고
    • Psychotic experiences in the general population: A twenty year prospective community study
    • One of the most recent studies of the potential link between Cannabis use and psychosis, ••
    • Rossler W, Riecher-Rossler A, Angst J et al. Psychotic experiences in the general population: a twenty year prospective community study. Schiz. Res. 92, 1-14 (2007). •• One of the most recent studies of the potential link between Cannabis use and psychosis.
    • (2007) Schiz. Res , vol.92 , pp. 1-14
    • Rossler, W.1    Riecher-Rossler, A.2    Angst, J.3
  • 60
    • 20944446077 scopus 로고    scopus 로고
    • Moderation of the effect of adolescent-onset cannabis use on adult psychosis by a functional polymorphism in the catechol-O-methyltransferase gene: Longitudinal evidence of a gene x environment interaction
    • Caspi A, Moffitt TE, Cannon M et al. Moderation of the effect of adolescent-onset cannabis use on adult psychosis by a functional polymorphism in the catechol-O-methyltransferase gene: longitudinal evidence of a gene x environment interaction. Biol. Psychiatry 57, 1117-1127 (2005).
    • (2005) Biol. Psychiatry , vol.57 , pp. 1117-1127
    • Caspi, A.1    Moffitt, T.E.2    Cannon, M.3
  • 61
    • 0032932488 scopus 로고    scopus 로고
    • Abstinence symptoms following oral THC administration in humans
    • Haney M, Ward AS, Comer SD et al. Abstinence symptoms following oral THC administration in humans. Psychopharmacol. (Berl.) 141, 385-404 (1999).
    • (1999) Psychopharmacol. (Berl.) , vol.141 , pp. 385-404
    • Haney, M.1    Ward, A.S.2    Comer, S.D.3
  • 62
    • 0032924511 scopus 로고    scopus 로고
    • Abstinence symptoms following smoked marijuana in humans
    • Haney M, Ward AS, Comer SD et al. Abstinence symptoms following smoked marijuana in humans. Psychopharmacol. (Berl.) 141, 395-404 (1999).
    • (1999) Psychopharmacol. (Berl.) , vol.141 , pp. 395-404
    • Haney, M.1    Ward, A.S.2    Comer, S.D.3
  • 63
    • 0036269429 scopus 로고    scopus 로고
    • A review of the published literature into cannabis withdrawal symptoms in human users
    • Smith NT. A review of the published literature into cannabis withdrawal symptoms in human users. Addiction 97, 621-632 (2002).
    • (2002) Addiction , vol.97 , pp. 621-632
    • Smith, N.T.1
  • 64
    • 0141451977 scopus 로고    scopus 로고
    • Cannabinoids: Reward, dependence and underlying neurochemical mechanisms-a review of recent preclinical data
    • Tanda G, Goldberg SR. Cannabinoids: reward, dependence and underlying neurochemical mechanisms-a review of recent preclinical data. Psychopharmacol. (Berl.) 169, 115-134 (2003).
    • (2003) Psychopharmacol. (Berl.) , vol.169 , pp. 115-134
    • Tanda, G.1    Goldberg, S.R.2


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