메뉴 건너뛰기




Volumn 7, Issue , 2007, Pages 1273-1284

Activation and regulation of cellular eicosanoid biosynthesis

Author keywords

5 lipoxygenase; Arachidonic acid; Biosynthesis; Cyclooxygenase; Eicosanoid; Leukotriene; Lipoxin; Prostanoids; Regulation

Indexed keywords

12 HYDROXYICOSATETRAENOIC ACID; 15 HYDROXYICOSATETRAENOIC ACID; ACETYLSALICYLIC ACID; CYCLOOXYGENASE 1 INHIBITOR; CYCLOOXYGENASE 2 INHIBITOR; CYTOCHROME P450; EPOXYICOSATRIENOIC ACID; IBUPROFEN; ICOSANOID; INDOMETACIN; LEUKOTRIENE; LIPOXIN; NONSTEROID ANTIINFLAMMATORY AGENT; PHOSPHOLIPASE A2; PROSTAGLANDIN SYNTHASE;

EID: 34548779243     PISSN: None     EISSN: 1537744X     Source Type: Journal    
DOI: 10.1100/tsw.2007.180     Document Type: Review
Times cited : (51)

References (57)
  • 1
    • 1842556175 scopus 로고    scopus 로고
    • Regulation of arachidonic acid availability for eicosanoid production
    • Leslie, C.C. (2004) Regulation of arachidonic acid availability for eicosanoid production. Biochem. Cell Biol. 82, 1-17.
    • (2004) Biochem. Cell Biol , vol.82 , pp. 1-17
    • Leslie, C.C.1
  • 2
    • 0036100383 scopus 로고    scopus 로고
    • Transcellular biosynthesis contributes to the production of leukotrienes during inflammatory responses in vivo
    • Fabre, J.E., Goulet, J.L., Riche, E., Nguyen, M., Coggins, K., Offenbacher, S., and Koller, B.H. (2002) Transcellular biosynthesis contributes to the production of leukotrienes during inflammatory responses in vivo. J. Clin. Invest. 109, 1373-1380.
    • (2002) J. Clin. Invest , vol.109 , pp. 1373-1380
    • Fabre, J.E.1    Goulet, J.L.2    Riche, E.3    Nguyen, M.4    Coggins, K.5    Offenbacher, S.6    Koller, B.H.7
  • 5
    • 0028969527 scopus 로고
    • Different intracellular locations for prostaglandin endoperoxide H synthase-1 and -2
    • Morita, I., Schindler, M., Regier, M.K., Otto, J.C., Hori, T., DeWitt, D.L., and Smith, W.L. (1995) Different intracellular locations for prostaglandin endoperoxide H synthase-1 and -2. J. Biol. Chem. 270, 10902-10908.
    • (1995) J. Biol. Chem , vol.270 , pp. 10902-10908
    • Morita, I.1    Schindler, M.2    Regier, M.K.3    Otto, J.C.4    Hori, T.5    DeWitt, D.L.6    Smith, W.L.7
  • 6
    • 0032540344 scopus 로고    scopus 로고
    • Subcellular localization of prostaglandin endoperoxide H synthases-1 and -2 by immunoelectron microscopy
    • Spencer, A.G., Woods, J.W., Arakawa, T., Singer, I.I., and Smith, W.L. (1998) Subcellular localization of prostaglandin endoperoxide H synthases-1 and -2 by immunoelectron microscopy. J. Biol. Chem. 273, 9886-9893.
    • (1998) J. Biol. Chem , vol.273 , pp. 9886-9893
    • Spencer, A.G.1    Woods, J.W.2    Arakawa, T.3    Singer, I.I.4    Smith, W.L.5
  • 7
    • 0345008359 scopus 로고
    • On the nature of the 5-lipoxygenase reaction in human leukocytes: Enzyme purification and requirement for multiple stimulatory factors
    • Rouzer, C.A. and Samuelsson, B. (1985) On the nature of the 5-lipoxygenase reaction in human leukocytes: enzyme purification and requirement for multiple stimulatory factors. Proc. Natl. Acad. Sci. U. S. A. 82, 6040-6044.
    • (1985) Proc. Natl. Acad. Sci. U. S. A , vol.82 , pp. 6040-6044
    • Rouzer, C.A.1    Samuelsson, B.2
  • 8
    • 0020586587 scopus 로고
    • Arachidonate 5-lipoxygenase of guinea pig peritoneal polymorphonuclear leukocytes: Activation by adenosine 5′-triphosphate
    • Ochi, K., Yoshimoto, T., Yamamoto, S., Taniguchi, K., and Miyamoto, T. (1983) Arachidonate 5-lipoxygenase of guinea pig peritoneal polymorphonuclear leukocytes: activation by adenosine 5′-triphosphate. J. Biol. Chem. 258, 5754-5758.
    • (1983) J. Biol. Chem , vol.258 , pp. 5754-5758
    • Ochi, K.1    Yoshimoto, T.2    Yamamoto, S.3    Taniguchi, K.4    Miyamoto, T.5
  • 9
    • 0037177904 scopus 로고    scopus 로고
    • Arachidonic acid promotes phosphorylation of 5-lipoxygenase at Ser-271 by MAPK-activated protein kinase 2 (MK2)
    • Werz, O., Szellas, D., Steinhilber, D., and Radmark, O. (2002) Arachidonic acid promotes phosphorylation of 5-lipoxygenase at Ser-271 by MAPK-activated protein kinase 2 (MK2). J. Biol. Chem. 277, 14793-14800.
    • (2002) J. Biol. Chem , vol.277 , pp. 14793-14800
    • Werz, O.1    Szellas, D.2    Steinhilber, D.3    Radmark, O.4
  • 10
    • 0036464591 scopus 로고    scopus 로고
    • Activation of 5-lipoxygenase by cell stress is calcium independent in human polymorphonuclear leukocytes
    • Werz, O., Burkert, E., Samuelsson, B., Radmark, O., and Steinhilber, D. (2002) Activation of 5-lipoxygenase by cell stress is calcium independent in human polymorphonuclear leukocytes. Blood 99, 1044-1052.
    • (2002) Blood , vol.99 , pp. 1044-1052
    • Werz, O.1    Burkert, E.2    Samuelsson, B.3    Radmark, O.4    Steinhilber, D.5
  • 11
    • 33644857422 scopus 로고    scopus 로고
    • Arachidonic acid regulates the translocation of 5-lipoxygenase to the nuclear membranes in human neutrophils
    • Flamand, N., Lefebvre, J., Surette, M.E., Picard, S., and Borgeat, P. (2006) Arachidonic acid regulates the translocation of 5-lipoxygenase to the nuclear membranes in human neutrophils. J. Biol. Chem. 281, 129-136.
    • (2006) J. Biol. Chem , vol.281 , pp. 129-136
    • Flamand, N.1    Lefebvre, J.2    Surette, M.E.3    Picard, S.4    Borgeat, P.5
  • 14
    • 0026723085 scopus 로고
    • Metabolism of 5(S)-hydroxy-6,8,11,14-eicosatetraenoic acid and other 5(S)-hydroxyeicosanoids by a specific dehydrogenase in human polymorphonuclear leukocytes
    • Powell, W.S., Gravelle, F., and Gravel, S. (1992) Metabolism of 5(S)-hydroxy-6,8,11,14-eicosatetraenoic acid and other 5(S)-hydroxyeicosanoids by a specific dehydrogenase in human polymorphonuclear leukocytes. J. Biol. Chem. 267, 19233-19241.
    • (1992) J. Biol. Chem , vol.267 , pp. 19233-19241
    • Powell, W.S.1    Gravelle, F.2    Gravel, S.3
  • 15
    • 0033967358 scopus 로고    scopus 로고
    • LTA(4)-derived 5-oxo-eicosatetraenoic acid: PH-dependent formation and interaction with the LTB(4) receptor of human polymorphonuclear leukocytes
    • Falgueyret, J. and Riendeau, D. (2000) LTA(4)-derived 5-oxo-eicosatetraenoic acid: pH-dependent formation and interaction with the LTB(4) receptor of human polymorphonuclear leukocytes. Biochim. Biophys. Acta 1484, 51-58.
    • (2000) Biochim. Biophys. Acta , vol.1484 , pp. 51-58
    • Falgueyret, J.1    Riendeau, D.2
  • 16
    • 0031717538 scopus 로고    scopus 로고
    • Activation of human polymorphonuclear leukocytes by products derived from the peroxidation of human red blood cell membranes
    • Hall, L.M. and Murphy, R.C. (1998) Activation of human polymorphonuclear leukocytes by products derived from the peroxidation of human red blood cell membranes. Chem. Res. Toxicol. 11, 1024-1031.
    • (1998) Chem. Res. Toxicol , vol.11 , pp. 1024-1031
    • Hall, L.M.1    Murphy, R.C.2
  • 17
    • 19544384684 scopus 로고    scopus 로고
    • Biochemistry, biology and chemistry of the 5-lipoxygenase product 5-oxo-ETE
    • Powell, W.S. and Rokach, J. (2005) Biochemistry, biology and chemistry of the 5-lipoxygenase product 5-oxo-ETE. Prog. Lipid Res. 44, 154-183.
    • (2005) Prog. Lipid Res , vol.44 , pp. 154-183
    • Powell, W.S.1    Rokach, J.2
  • 18
    • 0027396893 scopus 로고
    • Regulation of 5-lipoxygenase and 5-lipoxygenaseactivating protein expression in HL-60 cells
    • Bennett, C., Chiang, M., Monia, B., and Crooke, S. (1993) Regulation of 5-lipoxygenase and 5-lipoxygenaseactivating protein expression in HL-60 cells. Biochem. J. 289, 33-39.
    • (1993) Biochem. J , vol.289 , pp. 33-39
    • Bennett, C.1    Chiang, M.2    Monia, B.3    Crooke, S.4
  • 19
    • 0028486965 scopus 로고
    • Increases in 5-lipoxygenase activating protein expression account for enhanced capacity for 5-lipoxygenase metabolism which accompanies differentiation of peripheral blood monocytes into alveolar macrophages
    • Coffey, M.J., Wilcoxen, S.E., and Peters-Golden, M. (1994) Increases in 5-lipoxygenase activating protein expression account for enhanced capacity for 5-lipoxygenase metabolism which accompanies differentiation of peripheral blood monocytes into alveolar macrophages. Am. J. Respir. Cell Mol. Biol. 11, 153-158.
    • (1994) Am. J. Respir. Cell Mol. Biol , vol.11 , pp. 153-158
    • Coffey, M.J.1    Wilcoxen, S.E.2    Peters-Golden, M.3
  • 20
    • 0031816981 scopus 로고    scopus 로고
    • Altered expression and localization of 5-lipoxygenase accompany macrophage differentiation in the lung
    • Covin, R.B., Brock, T.G., Bailie, M.B., and Peters-Golden, M. (1998) Altered expression and localization of 5-lipoxygenase accompany macrophage differentiation in the lung. Am. J. Physiol. Lung Cell. Mol. Physiol. 275, L303-L310.
    • (1998) Am. J. Physiol. Lung Cell. Mol. Physiol , vol.275
    • Covin, R.B.1    Brock, T.G.2    Bailie, M.B.3    Peters-Golden, M.4
  • 21
    • 0027213308 scopus 로고
    • Transforming growth factor β upregulates 5-lipoxygenase activity during myeloid maturation
    • Steinhilber, D., Radmark, O., and Samuelsson, B. (1993) Transforming growth factor β upregulates 5-lipoxygenase activity during myeloid maturation. Proc. Natl. Acad. Sci. U. S. A. 90, 5984-5988.
    • (1993) Proc. Natl. Acad. Sci. U. S. A , vol.90 , pp. 5984-5988
    • Steinhilber, D.1    Radmark, O.2    Samuelsson, B.3
  • 22
    • 0028323505 scopus 로고
    • Granulocyte-macrophage colony-stimulating factor enhances 5-lipoxygenase levels in human polymorphonuclear leukocytes
    • Pouliot, M., McDonald, P., Khamzina, L., Borgeat, P., and McColl, S. (1994) Granulocyte-macrophage colony-stimulating factor enhances 5-lipoxygenase levels in human polymorphonuclear leukocytes. J. Immunol. 152, 851-858.
    • (1994) J. Immunol , vol.152 , pp. 851-858
    • Pouliot, M.1    McDonald, P.2    Khamzina, L.3    Borgeat, P.4    McColl, S.5
  • 23
    • 0028274089 scopus 로고
    • Granulocyte/macrophage colony-stimulating factor stimulates the expression of the 5-lipoxygenase-activating protein (FLAP) in human neutrophils
    • Pouliot, M., McDonald, P., Borgeat, P., and McColl, S. (1994) Granulocyte/macrophage colony-stimulating factor stimulates the expression of the 5-lipoxygenase-activating protein (FLAP) in human neutrophils. J. Exp. Med. 179, 1225-1232.
    • (1994) J. Exp. Med , vol.179 , pp. 1225-1232
    • Pouliot, M.1    McDonald, P.2    Borgeat, P.3    McColl, S.4
  • 24
    • 0027504207 scopus 로고
    • 5-Lipoxygenase and 5-lipoxygenase activating protein are localized in the nuclear envelope of activated human leukocytes
    • Woods, J.W., Evans, J.F., Ethier, D., Scott, S., Vickers, P.J., Hearn, L., Charleson, S., Heibein, J.A., and Singer, I.I. (1993) 5-Lipoxygenase and 5-lipoxygenase activating protein are localized in the nuclear envelope of activated human leukocytes. J. Exp. Med. 178, 1935-1946.
    • (1993) J. Exp. Med , vol.178 , pp. 1935-1946
    • Woods, J.W.1    Evans, J.F.2    Ethier, D.3    Scott, S.4    Vickers, P.J.5    Hearn, L.6    Charleson, S.7    Heibein, J.A.8    Singer, I.I.9
  • 25
    • 0030972551 scopus 로고    scopus 로고
    • Rapid import of cytosolic 5-lipoxygenase into the nucleus of neutrophils after in vivo recruitment and in vitro adherence
    • Brock, T.G., McNish, R.W., Bailie, M.B., and Peters-Golden, M. (1997) Rapid import of cytosolic 5-lipoxygenase into the nucleus of neutrophils after in vivo recruitment and in vitro adherence. J. Biol. Chem. 272, 8276-8280.
    • (1997) J. Biol. Chem , vol.272 , pp. 8276-8280
    • Brock, T.G.1    McNish, R.W.2    Bailie, M.B.3    Peters-Golden, M.4
  • 26
    • 7244239214 scopus 로고    scopus 로고
    • Multiple nuclear localization sequences allow fine control of 5-lipoxygenase nuclear import
    • Luo, M., Pang, C.W.M., Gerken, A.E., and Brock, T.G. (2004) Multiple nuclear localization sequences allow fine control of 5-lipoxygenase nuclear import. Traffic 5, 847-854.
    • (2004) Traffic , vol.5 , pp. 847-854
    • Luo, M.1    Pang, C.W.M.2    Gerken, A.E.3    Brock, T.G.4
  • 27
    • 0037064009 scopus 로고    scopus 로고
    • Structural and functional criteria reveal a new nuclear import sequence on the 5-lipoxygenase protein
    • Jones, S.M., Luo, M., Healy, A.M., Peters-Golden, M., and Brock, T.G. (2002) Structural and functional criteria reveal a new nuclear import sequence on the 5-lipoxygenase protein. J. Biol. Chem. 277, 38550-38556.
    • (2002) J. Biol. Chem , vol.277 , pp. 38550-38556
    • Jones, S.M.1    Luo, M.2    Healy, A.M.3    Peters-Golden, M.4    Brock, T.G.5
  • 29
    • 0035860822 scopus 로고    scopus 로고
    • 4 hydrolase with 5-lipoxygenase in nuclei of alveolar macrophages and rat basophilic leukemia cells but not neutrophils
    • 4 hydrolase with 5-lipoxygenase in nuclei of alveolar macrophages and rat basophilic leukemia cells but not neutrophils. J. Biol. Chem. 276, 35071-35077.
    • (2001) J. Biol. Chem , vol.276 , pp. 35071-35077
    • Brock, T.G.1    Maydanski, E.2    McNish, R.W.3    Peters-Golden, M.4
  • 31
    • 4744375385 scopus 로고    scopus 로고
    • Protein kinase A inhibits leukotriene synthesis by phosphorylation of 5-lipoxygenase on serine 523
    • Luo, M., Jones, S.M., Coffey, M.J., Peters-Golden, M., and Brock, T.G. (2004) Protein kinase A inhibits leukotriene synthesis by phosphorylation of 5-lipoxygenase on serine 523. J. Biol. Chem. 279, 41512-41520.
    • (2004) J. Biol. Chem , vol.279 , pp. 41512-41520
    • Luo, M.1    Jones, S.M.2    Coffey, M.J.3    Peters-Golden, M.4    Brock, T.G.5
  • 32
    • 28844492469 scopus 로고    scopus 로고
    • Phosphorylation by protein kinase A inhibits nuclear import of 5-lipoxygenase
    • Luo, M., Jones, S.M., Flamand, N., Aronoff, D.M., Peters-Golden, M., and Brock, T.G. (2005) Phosphorylation by protein kinase A inhibits nuclear import of 5-lipoxygenase. J. Biol. Chem. 280, 40609-40616.
    • (2005) J. Biol. Chem , vol.280 , pp. 40609-40616
    • Luo, M.1    Jones, S.M.2    Flamand, N.3    Aronoff, D.M.4    Peters-Golden, M.5    Brock, T.G.6
  • 33
    • 0034625136 scopus 로고    scopus 로고
    • 5-Lipoxygenase is phosphorylated by p38 kinase-dependent MAPKAP kinases
    • Werz, O., Klemm, J., Samuelsson, B., and Radmark, O. (2000) 5-Lipoxygenase is phosphorylated by p38 kinase-dependent MAPKAP kinases. Proc. Natl. Acad. Sci. U. S. A. 97, 5261-5266.
    • (2000) Proc. Natl. Acad. Sci. U. S. A , vol.97 , pp. 5261-5266
    • Werz, O.1    Klemm, J.2    Samuelsson, B.3    Radmark, O.4
  • 34
    • 0036719157 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinases phosphorylate 5-lipoxygenase and stimulate 5-lipoxygenase product formation in leukocytes
    • Werz, O., Burkert, E., Fischer, L., Szellas, D., Dishart, D., Samuelsson, B., Radmark, O., and Steinhilber, D. (2002) Extracellular signal-regulated kinases phosphorylate 5-lipoxygenase and stimulate 5-lipoxygenase product formation in leukocytes. FASEB J. 16, 1441-1443.
    • (2002) FASEB J , vol.16 , pp. 1441-1443
    • Werz, O.1    Burkert, E.2    Fischer, L.3    Szellas, D.4    Dishart, D.5    Samuelsson, B.6    Radmark, O.7    Steinhilber, D.8
  • 35
    • 0022914694 scopus 로고
    • Modulation by phorbol myristate acetate of arachidonic acid release and leukotriene synthesis by human polymorphonuclear leukocytes stimulated with A23187
    • McColl, S., Hurst, N., and Cleland, L. (1986) Modulation by phorbol myristate acetate of arachidonic acid release and leukotriene synthesis by human polymorphonuclear leukocytes stimulated with A23187. Biochem. Biophys. Res. Commun. 141, 399-404.
    • (1986) Biochem. Biophys. Res. Commun , vol.141 , pp. 399-404
    • McColl, S.1    Hurst, N.2    Cleland, L.3
  • 38
    • 24344510350 scopus 로고    scopus 로고
    • Anti-inflammatory circuitry: Lipoxin, aspirin-triggered lipoxins and their receptor ALX
    • Chiang, N., Arita, M., and Serhan, C.N. (2005) Anti-inflammatory circuitry: lipoxin, aspirin-triggered lipoxins and their receptor ALX. Prostaglandins Leukot. Essent. Fatty Acids 73, 163-177.
    • (2005) Prostaglandins Leukot. Essent. Fatty Acids , vol.73 , pp. 163-177
    • Chiang, N.1    Arita, M.2    Serhan, C.N.3
  • 41
    • 0029670175 scopus 로고    scopus 로고
    • Lipoxins inhibit leukotriene-stimulated interactions of human neutrophils and endothelial cells
    • Papayianni, A., Serhan, C.N., and Brady, H.R. (1996) Lipoxins inhibit leukotriene-stimulated interactions of human neutrophils and endothelial cells. J. Immunol. 159, 2264-2272.
    • (1996) J. Immunol , vol.159 , pp. 2264-2272
    • Papayianni, A.1    Serhan, C.N.2    Brady, H.R.3
  • 42
    • 0033591560 scopus 로고    scopus 로고
    • 4 inhibit tumor necrosis factor a-induced neutrophil responses and trafficking: Regulators of a cytokine-chemokine axis
    • 4 inhibit tumor necrosis factor a-induced neutrophil responses and trafficking: regulators of a cytokine-chemokine axis. J. Exp. Med. 189, 1923-1930.
    • (1999) J. Exp. Med , vol.189 , pp. 1923-1930
    • Hachicha, M.1    Pouliot, M.2    Petasis, N.A.3    Serhan, C.N.4
  • 43
    • 0029671266 scopus 로고    scopus 로고
    • 4 are potent stimuli for human monocyte migration and adhesion: Selective inactivation by dehydrogenation and reduction
    • 4 are potent stimuli for human monocyte migration and adhesion: selective inactivation by dehydrogenation and reduction. J. Exp. Med. 183, 137-146.
    • (1996) J. Exp. Med , vol.183 , pp. 137-146
    • Maddox, J.F.1    Serhan, C.N.2
  • 46
    • 20444481328 scopus 로고    scopus 로고
    • Host control of Mycobacterium tuberculosis is regulated by 5-lipoxygenase-dependent lipoxin production
    • Bafica, A., Scanga, C.A., Serhan, C., Machado, F., White, S., Sher, A., and Aliberti, J. (2005) Host control of Mycobacterium tuberculosis is regulated by 5-lipoxygenase-dependent lipoxin production. J. Clin. Invest. 115, 1601-1606.
    • (2005) J. Clin. Invest , vol.115 , pp. 1601-1606
    • Bafica, A.1    Scanga, C.A.2    Serhan, C.3    Machado, F.4    White, S.5    Sher, A.6    Aliberti, J.7
  • 48
    • 25444511054 scopus 로고    scopus 로고
    • Levy, B.D., Bonnans, C., Silverman, E.S., Palmer, L.J., Marigowda, G., Israel, E., and Severe Asthma Research Program, National Heart, Lung, and Blood Institute (2005) Diminished lipoxin biosynthesis in severe asthma. Am. J. Respir. Crit. Care Med. 172, 824-830.
    • Levy, B.D., Bonnans, C., Silverman, E.S., Palmer, L.J., Marigowda, G., Israel, E., and Severe Asthma Research Program, National Heart, Lung, and Blood Institute (2005) Diminished lipoxin biosynthesis in severe asthma. Am. J. Respir. Crit. Care Med. 172, 824-830.
  • 49
    • 33744550207 scopus 로고    scopus 로고
    • Inflammation and immune regulation by 12/15-lipoxygenases
    • Kuhn, H. and O'Donnell, V.B. (2006) Inflammation and immune regulation by 12/15-lipoxygenases. Prog. Lipid Res. 45, 334-356.
    • (2006) Prog. Lipid Res , vol.45 , pp. 334-356
    • Kuhn, H.1    O'Donnell, V.B.2
  • 54
    • 0027957514 scopus 로고
    • Epidermis contains platelet-type 12-lipoxygenase that is overexpressed in germinal layer keratinocytes in psoriasis
    • Hussain, H., Shornick, L.P., Shannon, V.R., Wilson, J.D., Funk, C.D., Pentland, A.P., and Holtzman, M.J. (1994) Epidermis contains platelet-type 12-lipoxygenase that is overexpressed in germinal layer keratinocytes in psoriasis. Am. J. Physiol. 266, C243-C253.
    • (1994) Am. J. Physiol , vol.266
    • Hussain, H.1    Shornick, L.P.2    Shannon, V.R.3    Wilson, J.D.4    Funk, C.D.5    Pentland, A.P.6    Holtzman, M.J.7
  • 55
    • 0035853069 scopus 로고    scopus 로고
    • Ribozyme-mediated inhibition of rat leukocyte-type 12-lipoxygenase prevents intimal hyperplasia in balloon-injured rat carotid arteries
    • Gu, J.L., Pei, H., Thomas, L., Nadler, J.L., Rossi, J.J., Lanting, L., and Natarajan, R. (2001) Ribozyme-mediated inhibition of rat leukocyte-type 12-lipoxygenase prevents intimal hyperplasia in balloon-injured rat carotid arteries. Circulation 103, 1446-1452.
    • (2001) Circulation , vol.103 , pp. 1446-1452
    • Gu, J.L.1    Pei, H.2    Thomas, L.3    Nadler, J.L.4    Rossi, J.J.5    Lanting, L.6    Natarajan, R.7
  • 57
    • 1842503012 scopus 로고    scopus 로고
    • Eicosanoid regulation of angiogenesis in tumors
    • Nie, D. and Honn, K.V. (2004) Eicosanoid regulation of angiogenesis in tumors. Semin. Thromb. Hemost. 30, 119-125.
    • (2004) Semin. Thromb. Hemost , vol.30 , pp. 119-125
    • Nie, D.1    Honn, K.V.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.