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Volumn , Issue , 2005, Pages 283-328

Nonparametric Linkage Analysis

Author keywords

GENEHUNTER algorithm and LOD score; Multipoint IBD method (MIM) and SIBPAIR methods; Nonparametric linkage analysis in human genetic mapping

Indexed keywords


EID: 34548734363     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780471781141.ch11     Document Type: Chapter
Times cited : (1)

References (97)
  • 1
    • 0036338150 scopus 로고    scopus 로고
    • Merlin-Rapid analysis of dense genetic maps using sparse gene flow trees
    • Abecasis GR, Cherny SS, Cookson WO, Cardon LR (2002): Merlin-Rapid analysis of dense genetic maps using sparse gene flow trees. Nat Genet 30:97-101.
    • (2002) Nat Genet , vol.30 , pp. 97-101
    • Abecasis, G.R.1    Cherny, S.S.2    Cookson, W.O.3    Cardon, L.R.4
  • 2
    • 0036144845 scopus 로고    scopus 로고
    • Quantification of type I error probabilities for heterogeneity LOD scores
    • Abreu PC, Hodge SE, Greenberg DA (2002): Quantification of type I error probabilities for heterogeneity LOD scores. Genet Epidemiol 22:156-169.
    • (2002) Genet Epidemiol , vol.22 , pp. 156-169
    • Abreu, P.C.1    Hodge, S.E.2    Greenberg, D.A.3
  • 3
    • 0031966959 scopus 로고    scopus 로고
    • Multipoint quantitative-trait linkage analysis in general pedigrees
    • Almasy L, Blangero J (1998): Multipoint quantitative-trait linkage analysis in general pedigrees. Am J Hum Genet 62:1198-1211.
    • (1998) Am J Hum Genet , vol.62 , pp. 1198-1211
    • Almasy, L.1    Blangero, J.2
  • 5
    • 0025172940 scopus 로고
    • The probabilistic determination of identity-bydescent sharing for pairs of relatives from pedigrees
    • Amos CI, Dawson DV, Elston RC (1990): The probabilistic determination of identity-bydescent sharing for pairs of relatives from pedigrees. Am J Hum Genet 47:842-853.
    • (1990) Am J Hum Genet , vol.47 , pp. 842-853
    • Amos, C.I.1    Dawson, D.V.2    Elston, R.C.3
  • 8
    • 0025093523 scopus 로고
    • The power of identity-by-state methods for linkage analysis
    • Bishop DT, Williamson JA (1990): The power of identity-by-state methods for linkage analysis. Am J Hum Genet 46:254-265.
    • (1990) Am J Hum Genet , vol.46 , pp. 254-265
    • Bishop, D.T.1    Williamson, J.A.2
  • 9
    • 0021957675 scopus 로고
    • A comparison of sib-pair linkage tests for disease susceptibility loci
    • Blackwelder WC, Elston RC (1985): A comparison of sib-pair linkage tests for disease susceptibility loci. Genet Epidemiol 2:85-98.
    • (1985) Genet Epidemiol , vol.2 , pp. 85-98
    • Blackwelder, W.C.1    Elston, R.C.2
  • 10
    • 0028071382 scopus 로고
    • The power of interval mapping of quantitative trait loci, using selected sibpairs
    • Cardon LR, Fulker DW (1994): The power of interval mapping of quantitative trait loci, using selected sibpairs. Am J Hum Genet 55:825-833.
    • (1994) Am J Hum Genet , vol.55 , pp. 825-833
    • Cardon, L.R.1    Fulker, D.W.2
  • 12
    • 0026047218 scopus 로고
    • Linkage analysis of quantitative traits: Increased power by using selected samples
    • Carey G, Williamson J (1991): Linkage analysis of quantitative traits: Increased power by using selected samples. Am J Hum Genet 49:786-796.
    • (1991) Am J Hum Genet , vol.49 , pp. 786-796
    • Carey, G.1    Williamson, J.2
  • 14
    • 0028220901 scopus 로고
    • Robust genetic linkage analysis based on a score test of homogeneity: The weighted pairwise correlation statistic
    • Commenges D (1994): Robust genetic linkage analysis based on a score test of homogeneity: The weighted pairwise correlation statistic. Genet Epidemiol 11:189-200.
    • (1994) Genet Epidemiol , vol.11 , pp. 189-200
    • Commenges, D.1
  • 15
    • 0032759021 scopus 로고    scopus 로고
    • Multipoint linkage analysis using the weightedpairwise correlation statistic
    • Commenges D, Beurton-Aimar M (1999): Multipoint linkage analysis using the weightedpairwise correlation statistic. Genet Epidemiol 17(Suppl 1):S515-S519.
    • (1999) Genet Epidemiol , vol.17 , Issue.SUPPL. 1
    • Commenges, D.1    Beurton-Aimar, M.2
  • 17
    • 0029112753 scopus 로고
    • Two-locus maximum lod score analysis of a multifactorial trait: Joint consideration of IDDM2 and IDDM4 with IDDM1 in type I diabetes
    • Cordell HJ, Todd JA, Bennett ST, Kawaguchi Y, Farrall M (1995): Two-locus maximum lod score analysis of a multifactorial trait: Joint consideration of IDDM2 and IDDM4 with IDDM1 in type I diabetes. Am J Hum Genet 57:920-934.
    • (1995) Am J Hum Genet , vol.57 , pp. 920-934
    • Cordell, H.J.1    Todd, J.A.2    Bennett, S.T.3    Kawaguchi, Y.4    Farrall, M.5
  • 18
    • 0024517006 scopus 로고
    • The insulin gene and susceptibility to IDDM
    • Cox DW, Spielman RS (1989): The insulin gene and susceptibility to IDDM. Genet Epidemiol 6:65-69.
    • (1989) Genet Epidemiol , vol.6 , pp. 65-69
    • Cox, D.W.1    Spielman, R.S.2
  • 19
    • 84889849132 scopus 로고    scopus 로고
    • A semiparametric model allowing exact calculations of likelihoods implemented in GENEHUNTER
    • in press
    • Cox NJ, Frigge M, Donnelly P, Kong A (in press): A semiparametric model allowing exact calculations of likelihoods implemented in GENEHUNTER. Genet Epidemiol.
    • Genet Epidemiol
    • Cox, N.J.1    Frigge, M.2    Donnelly, P.3    Kong, A.4
  • 20
    • 0032928542 scopus 로고    scopus 로고
    • Loci on chromosomes 2 (NIDDM1) and 15 interact to increase susceptibility to diabetes in Mexican Americans
    • Cox NJ, Frigge M, Nicolae DL, Concannon P, Hanis CL, Bell GI, Kong A (1999): Loci on chromosomes 2 (NIDDM1) and 15 interact to increase susceptibility to diabetes in Mexican Americans. Nat Genet 21:213-215.
    • (1999) Nat Genet , vol.21 , pp. 213-215
    • Cox, N.J.1    Frigge, M.2    Nicolae, D.L.3    Concannon, P.4    Hanis, C.L.5    Bell, G.I.6    Kong, A.7
  • 22
    • 0029918883 scopus 로고    scopus 로고
    • Nonparametric simulation-based statistics for detecting linkage in general pedigrees
    • Davis S, Schroeder M, Goldin LR, Weeks DE (1996): Nonparametric simulation-based statistics for detecting linkage in general pedigrees. Am J Hum Genet 58:867-880.
    • (1996) Am J Hum Genet , vol.58 , pp. 867-880
    • Davis, S.1    Schroeder, M.2    Goldin, L.R.3    Weeks, D.E.4
  • 23
    • 0025695910 scopus 로고
    • Extensions to sib-pair linkage tests applicable to disorders characterized by delayed onset
    • Dawson DV, Kaplan NL, Elston RC (1990): Extensions to sib-pair linkage tests applicable to disorders characterized by delayed onset. Genet Epidemiol 7:453-466.
    • (1990) Genet Epidemiol , vol.7 , pp. 453-466
    • Dawson, D.V.1    Kaplan, N.L.2    Elston, R.C.3
  • 25
    • 0028090099 scopus 로고
    • Interactive effect of two candidate genes in a disease: Extension of the marker-association-segregation x2 method
    • Dizier MH, Babron MC, Clerget-Darpoux F (1994): Interactive effect of two candidate genes in a disease: Extension of the marker-association-segregation x2 method. Am J Hum Genet 55:1042-1049.
    • (1994) Am J Hum Genet , vol.55 , pp. 1042-1049
    • Dizier, M.H.1    Babron, M.C.2    Clerget-Darpoux, F.3
  • 26
    • 0022997186 scopus 로고
    • Two-disease locus model: Sibpair method using information on both HLA and Gm
    • Dizier MH, Clerget-Darpoux F (1986): Two-disease locus model: Sibpair method using information on both HLA and Gm. Genet Epidemiol 3:343-356.
    • (1986) Genet Epidemiol , vol.3 , pp. 343-356
    • Dizier, M.H.1    Clerget-Darpoux, F.2
  • 29
    • 0015183542 scopus 로고
    • A general model for the genetic analysis of pedigree data
    • Elston RC, Stewart J (1971): A general model for the genetic analysis of pedigree data. Hum Hered 21:523-542.
    • (1971) Hum Hered , vol.21 , pp. 523-542
    • Elston, R.C.1    Stewart, J.2
  • 30
    • 0030992951 scopus 로고    scopus 로고
    • Affected sibpair linkage tests for multiple linked susceptibility genes
    • Farrall M (1997): Affected sibpair linkage tests for multiple linked susceptibility genes. Genet Epidemiol 14:103-115.
    • (1997) Genet Epidemiol , vol.14 , pp. 103-115
    • Farrall, M.1
  • 31
    • 0042262709 scopus 로고
    • The detection of linkage with recessive abnormalities
    • Fisher R (1935): The detection of linkage with recessive abnormalities. Ann Eugen 6:339-351.
    • (1935) Ann Eugen , vol.6 , pp. 339-351
    • Fisher, R.1
  • 32
    • 0028236482 scopus 로고
    • A sib-pair approach to interval mapping of quantitative trait loci
    • Fulker DW, Cardon LR (1994): A sib-pair approach to interval mapping of quantitative trait loci. Am J Hum Genet 54:1092-1103.
    • (1994) Am J Hum Genet , vol.54 , pp. 1092-1103
    • Fulker, D.W.1    Cardon, L.R.2
  • 33
    • 0028947057 scopus 로고
    • Multipoint interval mapping of quantitative trait loci
    • Fulker DW, Cherny SS, Cardon LR (1995): Multipoint interval mapping of quantitative trait loci. Am J Hum Genet 56:1224-1233.
    • (1995) Am J Hum Genet , vol.56 , pp. 1224-1233
    • Fulker, D.W.1    Cherny, S.S.2    Cardon, L.R.3
  • 34
    • 0025245437 scopus 로고
    • Multipoint analysis of human quantitative genetic variation
    • Goldgar DE (1990): Multipoint analysis of human quantitative genetic variation. Am J Hum Genet 47:957-967.
    • (1990) Am J Hum Genet , vol.47 , pp. 957-967
    • Goldgar, D.E.1
  • 35
    • 0030903121 scopus 로고    scopus 로고
    • Optimal strategies for mapping complex diseases in the presence of multiple loci
    • Goldgar DE, Easton DF (1997): Optimal strategies for mapping complex diseases in the presence of multiple loci. Am J Hum Genet 60:1222-1232.
    • (1997) Am J Hum Genet , vol.60 , pp. 1222-1232
    • Goldgar, D.E.1    Easton, D.F.2
  • 36
    • 0028143018 scopus 로고
    • Systematic populationbased assessment of cancer risk in first-degree relatives of cancer probands
    • Goldgar DE, Easton DF, Cannon-Albright LA, Skolnick MH (1994): Systematic populationbased assessment of cancer risk in first-degree relatives of cancer probands. J Natl Cancer Inst 86:1600-1608.
    • (1994) J Natl Cancer Inst , vol.86 , pp. 1600-1608
    • Goldgar, D.E.1    Easton, D.F.2    Cannon-Albright, L.A.3    Skolnick, M.H.4
  • 37
    • 0026600683 scopus 로고
    • Comparison of multipoint identity-by-descent method with parametric multipoint linkage analysis for mapping quantitative traits
    • Goldgar DE, Oniki RS (1992): Comparison of multipoint identity-by-descent method with parametric multipoint linkage analysis for mapping quantitative traits. Am J Hum Genet 50:598-606.
    • (1992) Am J Hum Genet , vol.50 , pp. 598-606
    • Goldgar, D.E.1    Oniki, R.S.2
  • 38
    • 0027440662 scopus 로고
    • Two-locus models of disease: Comparison of likelihood and nonparametric linkage methods
    • Goldin LR, Weeks DE (1993): Two-locus models of disease: Comparison of likelihood and nonparametric linkage methods. Am J Hum Genet 53:908-915.
    • (1993) Am J Hum Genet , vol.53 , pp. 908-915
    • Goldin, L.R.1    Weeks, D.E.2
  • 41
    • 0033928210 scopus 로고    scopus 로고
    • Chromosome 6p influences on different dyslexia-related cognitive processes: Further confirmation
    • Grigorenko EL, Wood FB, Meyer MS, Pauls DL (2000): Chromosome 6p influences on different dyslexia-related cognitive processes: Further confirmation. Am J Hum Genet 66:715-723.
    • (2000) Am J Hum Genet , vol.66 , pp. 715-723
    • Grigorenko, E.L.1    Wood, F.B.2    Meyer, M.S.3    Pauls, D.L.4
  • 42
    • 0034098774 scopus 로고    scopus 로고
    • Allegro, a new computer program for multipoint linkage analysis
    • Gudbjartsson DF, Jonasson K, Frigge ML, Kong A (2000): Allegro, a new computer program for multipoint linkage analysis. Nat Genet 25:12-13.
    • (2000) Nat Genet , vol.25 , pp. 12-13
    • Gudbjartsson, D.F.1    Jonasson, K.2    Frigge, M.L.3    Kong, A.4
  • 45
    • 0002439565 scopus 로고
    • Methods for the detection of autosomal linkage in man
    • Haldane JBS (1934): Methods for the detection of autosomal linkage in man. Ann Eugen 6:26-65.
    • (1934) Ann Eugen , vol.6 , pp. 26-65
    • Haldane, J.B.S.1
  • 46
    • 78651020237 scopus 로고
    • A new estimate of the linkage between the genes for color blindness and hemophilia in man
    • Haldane JBS, Smith CAB (1947): A new estimate of the linkage between the genes for color blindness and hemophilia in man. Ann Eugen 14:10-31.
    • (1947) Ann Eugen , vol.14 , pp. 10-31
    • Haldane, J.B.S.1    Smith, C.A.B.2
  • 48
    • 9044243415 scopus 로고    scopus 로고
    • A genome-wide search for human non-insulin-dependent (type 2) diabetes genes reveals a major susceptibility locus on chromosome 2
    • Hanis CL, Boerwinkle E, Chakraborty R, Ellsworth DL, Concannon P, Stirling B, Morrison VA, et al (1996): A genome-wide search for human non-insulin-dependent (type 2) diabetes genes reveals a major susceptibility locus on chromosome 2. Nat Genet 13:161-166.
    • (1996) Nat Genet , vol.13 , pp. 161-166
    • Hanis, C.L.1    Boerwinkle, E.2    Chakraborty, R.3    Ellsworth, D.L.4    Concannon, P.5    Stirling, B.6    Morrison, V.A.7
  • 49
    • 0015309467 scopus 로고
    • The investigation of linkage between a quantitative trait and a marker locus
    • Haseman JK, Elston RC (1972): The investigation of linkage between a quantitative trait and a marker locus. Behav Genet 2:3-19.
    • (1972) Behav Genet , vol.2 , pp. 3-19
    • Haseman, J.K.1    Elston, R.C.2
  • 50
    • 0032433332 scopus 로고    scopus 로고
    • Genetic linkage analysis of complex genetic traits by using affected sibling pairs
    • Hauser ER, Boehnke M (1998): Genetic linkage analysis of complex genetic traits by using affected sibling pairs. Biometrics 54:1238-1246.
    • (1998) Biometrics , vol.54 , pp. 1238-1246
    • Hauser, E.R.1    Boehnke, M.2
  • 51
    • 0029996490 scopus 로고    scopus 로고
    • Affected-sib-pair interval mapping and exclusion for complex genetic traits: Sampling considerations
    • Hauser ER, Boehnke M, Guo SW, Risch N (1996): Affected-sib-pair interval mapping and exclusion for complex genetic traits: Sampling considerations. Genet Epidemiol 13:117-137.
    • (1996) Genet Epidemiol , vol.13 , pp. 117-137
    • Hauser, E.R.1    Boehnke, M.2    Guo, S.W.3    Risch, N.4
  • 52
    • 0016690548 scopus 로고
    • Quantitative linkage: A statistical procedure for its detection and estimation
    • Hill AP (1975): Quantitative linkage: A statistical procedure for its detection and estimation. Ann Hum Genet 38:439-449.
    • (1975) Ann Hum Genet , vol.38 , pp. 439-449
    • Hill, A.P.1
  • 53
    • 0019480329 scopus 로고
    • Some epistatic two-locus models of disease. I. Relative risks and identityby-descent distributions in affected sib pairs
    • Hodge SE (1981): Some epistatic two-locus models of disease. I. Relative risks and identityby-descent distributions in affected sib pairs. Am J Hum Genet 33:381-395.
    • (1981) Am J Hum Genet , vol.33 , pp. 381-395
    • Hodge, S.E.1
  • 54
    • 0021669736 scopus 로고
    • The information contained in multiple sibling pairs
    • Hodge SE (1984): The information contained in multiple sibling pairs. Genet Epidemiol 1:109-122.
    • (1984) Genet Epidemiol , vol.1 , pp. 109-122
    • Hodge, S.E.1
  • 55
    • 0028029930 scopus 로고
    • Lods, wrods, and mods: The interpretation of lod scores calculated under different models
    • Hodge SE, Elston RC (1994): Lods, wrods, and mods: The interpretation of lod scores calculated under different models. Genet Epidemiol 11:329-342.
    • (1994) Genet Epidemiol , vol.11 , pp. 329-342
    • Hodge, S.E.1    Elston, R.C.2
  • 56
    • 0027529253 scopus 로고
    • Asymptotic properties of affected-sib-pair linkage analysis
    • Holmans P (1993): Asymptotic properties of affected-sib-pair linkage analysis. Am J Hum Genet 52:362-374.
    • (1993) Am J Hum Genet , vol.52 , pp. 362-374
    • Holmans, P.1
  • 57
    • 0033772073 scopus 로고    scopus 로고
    • Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus
    • Horikawa Y, Oda N, Cox NJ, Li X, Orho-Melander M, Hara M, Hinokio Y, et al (2000): Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus. Nat Genet 26:163-175.
    • (2000) Nat Genet , vol.26 , pp. 163-175
    • Horikawa, Y.1    Oda, N.2    Cox, N.J.3    Li, X.4    Orho-Melander, M.5    Hara, M.6    Hinokio, Y.7
  • 58
    • 84889850488 scopus 로고
    • Macular corneal dystrophy in Iceland: A clinical, genealogical and immunohistochemical study of twenty-eight cases
    • under review
    • Jonasson F, Oshima E, Klintworth GK, Thonar EJM, Smith CF, Johannasson JH (1995): Macular corneal dystrophy in Iceland: A clinical, genealogical and immunohistochemical study of twenty-eight cases. Ophthalmology, under review.
    • (1995) Ophthalmology
    • Jonasson, F.1    Oshima, E.2    Klintworth, G.K.3    Thonar, E.J.M.4    Smith, C.F.5    Johannasson, J.H.6
  • 59
    • 0028030120 scopus 로고
    • Two-locus disease models with two marker loci: The power of affected-sib-pair tests
    • Knapp M, Seuchter SA, Baur MP (1994): Two-locus disease models with two marker loci: The power of affected-sib-pair tests. Am J Hum Genet 55:1030-1041.
    • (1994) Am J Hum Genet , vol.55 , pp. 1030-1041
    • Knapp, M.1    Seuchter, S.A.2    Baur, M.P.3
  • 60
    • 0030728925 scopus 로고    scopus 로고
    • Allele-sharing models: LOD scores and accurate linkage tests
    • Kong A, Cox NJ (1997): Allele-sharing models: LOD scores and accurate linkage tests. Am J Hum Genet 61:1179-1188.
    • (1997) Am J Hum Genet , vol.61 , pp. 1179-1188
    • Kong, A.1    Cox, N.J.2
  • 61
    • 0029886532 scopus 로고    scopus 로고
    • Parametric and nonparametric linkage analysis: A unified multipoint approach
    • Kruglyak L, Daly MJ, Reeve-Daly MP, Lander ES (1996): Parametric and nonparametric linkage analysis: A unified multipoint approach. Am J Hum Genet 58:1347-1363.
    • (1996) Am J Hum Genet , vol.58 , pp. 1347-1363
    • Kruglyak, L.1    Daly, M.J.2    Reeve-Daly, M.P.3    Lander, E.S.4
  • 62
    • 0028899938 scopus 로고
    • A nonparametric approach for mapping quantitative trait loci
    • Kruglyak L, Lander ES (1995): A nonparametric approach for mapping quantitative trait loci. Genetics 139:1421-1428.
    • (1995) Genetics , vol.139 , pp. 1421-1428
    • Kruglyak, L.1    Lander, E.S.2
  • 63
    • 0000803318 scopus 로고
    • Construction of multilocus genetic linkage maps in humans
    • Lander ES, Green P (1987): Construction of multilocus genetic linkage maps in humans. Proc Natl Acad Sci USA 84:2363-2367.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 2363-2367
    • Lander, E.S.1    Green, P.2
  • 64
    • 0022744810 scopus 로고
    • The affected sib-pair method using identity by state relations
    • Lange K (1986): The affected sib-pair method using identity by state relations. Am J Hum Genet 39:148-150.
    • (1986) Am J Hum Genet , vol.39 , pp. 148-150
    • Lange, K.1
  • 65
    • 0029619444 scopus 로고
    • Screening for linkage using a multipoint identity-by-descent method
    • Lewis CM, Goldgar DE (1995): Screening for linkage using a multipoint identity-by-descent method. Genet Epidemiol 12:777-782.
    • (1995) Genet Epidemiol , vol.12 , pp. 777-782
    • Lewis, C.M.1    Goldgar, D.E.2
  • 66
    • 70449248171 scopus 로고
    • Testing association of metric traits and marker genes
    • Lowry DC, Schultz F (1959): Testing association of metric traits and marker genes. Ann Hum Genet 23:83-90.
    • (1959) Ann Hum Genet , vol.23 , pp. 83-90
    • Lowry, D.C.1    Schultz, F.2
  • 67
    • 0035071608 scopus 로고    scopus 로고
    • Efficient multipoint linkage analysis through reduction of inheritance space
    • Markianos K, Daly MJ, Kruglyak L (2001): Efficient multipoint linkage analysis through reduction of inheritance space. Am J Hum Genet 68:963-977.
    • (2001) Am J Hum Genet , vol.68 , pp. 963-977
    • Markianos, K.1    Daly, M.J.2    Kruglyak, L.3
  • 69
    • 0043048571 scopus 로고
    • Sequential tests for the detection of linkage
    • Morton NE (1955): Sequential tests for the detection of linkage. Am J Hum Genet 7:277-318.
    • (1955) Am J Hum Genet , vol.7 , pp. 277-318
    • Morton, N.E.1
  • 70
    • 0028931393 scopus 로고
    • Multipoint linkage analysis using sibpairs: An interval mapping approach for dichotomous outcomes
    • Olson JM (1995a): Multipoint linkage analysis using sibpairs: An interval mapping approach for dichotomous outcomes. Am J Hum Genet 56:788-798.
    • (1995) Am J Hum Genet , vol.56 , pp. 788-798
    • Olson, J.M.1
  • 71
    • 0029041213 scopus 로고
    • Robust multipoint linkage analysis: An extension of the Haseman-Elston method
    • Olson JM (1995b): Robust multipoint linkage analysis: An extension of the Haseman-Elston method. Genet Epidemiol 12:177-193.
    • (1995) Genet Epidemiol , vol.12 , pp. 177-193
    • Olson, J.M.1
  • 72
    • 0000877874 scopus 로고
    • Genetic linkage in graded human characters
    • Penrose L (1938): Genetic linkage in graded human characters. Ann Eugen 9:133-138.
    • (1938) Ann Eugen , vol.9 , pp. 133-138
    • Penrose, L.1
  • 73
    • 0000877874 scopus 로고
    • The detection of autosomal linkage in data which consists of pairs of brothers and sisters of unspecified parentage
    • Penrose LS (1935): The detection of autosomal linkage in data which consists of pairs of brothers and sisters of unspecified parentage. Ann Eugen 6:133-138.
    • (1935) Ann Eugen , vol.6 , pp. 133-138
    • Penrose, L.S.1
  • 74
    • 0000632243 scopus 로고
    • The general purpose sib-pair linkage test
    • Penrose LS (1953): The general purpose sib-pair linkage test. Ann Eugen 18:120-124.
    • (1953) Ann Eugen , vol.18 , pp. 120-124
    • Penrose, L.S.1
  • 78
    • 0023135007 scopus 로고
    • Assessing the role of HLA-linked and unlinked determinants of disease
    • Risch N (1987): Assessing the role of HLA-linked and unlinked determinants of disease. Am J Hum Genet 40:1-14.
    • (1987) Am J Hum Genet , vol.40 , pp. 1-14
    • Risch, N.1
  • 79
    • 0025019555 scopus 로고
    • Linkage strategies for genetically complex traits. I. Multilocus models
    • Risch N (1990a): Linkage strategies for genetically complex traits. I. Multilocus models. Am J Hum Genet 46:222-228.
    • (1990) Am J Hum Genet , vol.46 , pp. 222-228
    • Risch, N.1
  • 80
    • 0025008677 scopus 로고
    • Linkage strategies for genetically complex traits. II. The power of affected relative pairs
    • Risch N (1990b): Linkage strategies for genetically complex traits. II. The power of affected relative pairs. Am J Hum Genet 46:229-241.
    • (1990) Am J Hum Genet , vol.46 , pp. 229-241
    • Risch, N.1
  • 81
    • 0025020461 scopus 로고
    • Linkage strategies for genetically complex traits. III. The effect of marker polymorphism on analysis of affected relative pairs
    • Risch N (1990c): Linkage strategies for genetically complex traits. III. The effect of marker polymorphism on analysis of affected relative pairs. Am J Hum Genet 46:242-253.
    • (1990) Am J Hum Genet , vol.46 , pp. 242-253
    • Risch, N.1
  • 82
    • 0029001682 scopus 로고
    • Extreme discordant sib pairs for mapping quantitative trait loci in humans
    • Risch N, Zhang H (1995): Extreme discordant sib pairs for mapping quantitative trait loci in humans. Science 268:1584-1589.
    • (1995) Science , vol.268 , pp. 1584-1589
    • Risch, N.1    Zhang, H.2
  • 83
    • 0029979336 scopus 로고    scopus 로고
    • Mapping quantitative trait loci with extreme discordant sib pairs: Sample size considerations
    • Risch N, Zhang H (1996): Mapping quantitative trait loci with extreme discordant sib pairs: Sample size considerations. Am J Hum Genet 58:836-843.
    • (1996) Am J Hum Genet , vol.58 , pp. 836-843
    • Risch, N.1    Zhang, H.2
  • 84
    • 84889829408 scopus 로고
    • An extension of the weighted pairwise correlation statistic (WPC) to test for linkage in the presence of gene-environment interaction
    • Rogus JJ, Haines JL, Pericak-Vance MA, Harrington DP (1995): An extension of the weighted pairwise correlation statistic (WPC) to test for linkage in the presence of gene-environment interaction. Am J Hum Genet 57:A171.
    • (1995) Am J Hum Genet , vol.57
    • Rogus, J.J.1    Haines, J.L.2    Pericak-Vance, M.A.3    Harrington, D.P.4
  • 87
    • 0034972488 scopus 로고    scopus 로고
    • A survey of affected-sibship statistics for nonparametric linkage analysis
    • Sengul H, Weeks DE, Feingold E (2001): A survey of affected-sibship statistics for nonparametric linkage analysis. Am J Hum Genet 69:179-190.
    • (2001) Am J Hum Genet , vol.69 , pp. 179-190
    • Sengul, H.1    Weeks, D.E.2    Feingold, E.3
  • 88
    • 0016756644 scopus 로고
    • A non-parametric test for linkage with a quantitative character
    • Smith CAB (1975): A non-parametric test for linkage with a quantitative character. Ann Hum Genet 38:451-460.
    • (1975) Ann Hum Genet , vol.38 , pp. 451-460
    • Smith, C.A.B.1
  • 89
    • 0035741831 scopus 로고    scopus 로고
    • Multipoint estimation of identity-by-descent probabilities at arbitrary positions among marker loci on general pedigrees
    • Sobel E, Sengul H, Weeks DE (2001): Multipoint estimation of identity-by-descent probabilities at arbitrary positions among marker loci on general pedigrees. Hum Hered 52:121-131.
    • (2001) Hum Hered , vol.52 , pp. 121-131
    • Sobel, E.1    Sengul, H.2    Weeks, D.E.3
  • 90
    • 0019226693 scopus 로고
    • Gene dosage and suceptibility to insulindependent diabetes
    • Spielman RS, Baker L, Zmijewski CM (1980): Gene dosage and suceptibility to insulindependent diabetes. Ann Hum Genet 44:135-150.
    • (1980) Ann Hum Genet , vol.44 , pp. 135-150
    • Spielman, R.S.1    Baker, L.2    Zmijewski, C.M.3
  • 92
    • 0018150112 scopus 로고
    • The generalized sib pair IBD distribution: Its use in the detection of linkage
    • Suarez BK, Rice JP, Reich T (1978): The generalized sib pair IBD distribution: Its use in the detection of linkage. Ann Hum Genet 42:87-94.
    • (1978) Ann Hum Genet , vol.42 , pp. 87-94
    • Suarez, B.K.1    Rice, J.P.2    Reich, T.3
  • 93
    • 0023894935 scopus 로고
    • The affected-pedigree member method of linkage analysis
    • Weeks DE, Lange K (1988): The affected-pedigree member method of linkage analysis. Am J Hum Genet 42:315-326.
    • (1988) Am J Hum Genet , vol.42 , pp. 315-326
    • Weeks, D.E.1    Lange, K.2
  • 94
    • 0026510552 scopus 로고
    • A multilocus extension of the affected-pedigree-member method of linkage analysis
    • Weeks DE, Lange K (1992): A multilocus extension of the affected-pedigree-member method of linkage analysis. Am J Hum Genet 50:859-868.
    • (1992) Am J Hum Genet , vol.50 , pp. 859-868
    • Weeks, D.E.1    Lange, K.2
  • 95
    • 0028301661 scopus 로고
    • A class of tests for linkage using affected pedigree members
    • Whittemore AS, Halpern J (1994): A class of tests for linkage using affected pedigree members. Biometrics 50:118-127.
    • (1994) Biometrics , vol.50 , pp. 118-127
    • Whittemore, A.S.1    Halpern, J.2
  • 96
    • 0033496277 scopus 로고    scopus 로고
    • Power of variance component linkage analysis to detect quantitative trait loci
    • Williams JT, Blangero J (1999): Power of variance component linkage analysis to detect quantitative trait loci. Ann Hum Genet 63:545-563.
    • (1999) Ann Hum Genet , vol.63 , pp. 545-563
    • Williams, J.T.1    Blangero, J.2
  • 97
    • 0025048029 scopus 로고
    • On the asymptotic behavior of the estimate of the recombination fraction under the null hypothesis of no linkage when the model is misspecified
    • Williamson JA, Amos CI (1990): On the asymptotic behavior of the estimate of the recombination fraction under the null hypothesis of no linkage when the model is misspecified. Genet Epidemiol 7:309-318.
    • (1990) Genet Epidemiol , vol.7 , pp. 309-318
    • Williamson, J.A.1    Amos, C.I.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.