Expression and clinical significance of interleukin-24 mRNA in keloid

Journal of Clinical Rehabilitative Tissue Engineering Research

Volumn 11, Issue 32, 2007, Pages 6432-6435

  Li, Jian Chi ^a   Liang, Jie ^a   Liu, Shao Jun ^a   Zhang, P H ^a   Peng, Z ^a   Li, P ^a  

^a GUANGDONG MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; DNA FRAGMENT; FORMALDEHYDE; INTERLEUKIN 24; LIQUID NITROGEN; MESSENGER RNA; RNA;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DENATURING GRADIENT GEL ELECTROPHORESIS; DNA SYNTHESIS; DOWN REGULATION; ELECTROPHORESIS; FACE; GENE AMPLIFICATION; GENE EXPRESSION; GENE THERAPY; HUMAN; HUMAN TISSUE; KELOID; LIMB; NUCLEOTIDE SEQUENCE; REVERSE TRANSCRIPTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; SCAR; SCORING SYSTEM; SPECTROPHOTOMETER; STATISTICAL SIGNIFICANCE; THORAX; TISSUE PRESERVATION; TISSUE SECTION;

EID: 34548707849     PISSN: 16738225     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Chevray PM, Manson PN. Keloid scars are formed by polyclonal fibroblasts. Ann Plast Surg 2004;52(6):605-608
2. Funayama E, Chodon T, Oyama A, et al. Keratinocytes promote proliferation and inhibit apoptosis of the underlying fibroblasts: an important role in the pathogenesis of keloid. J Invest Dermatol 2003;121 (6):1326-1331
3. Jiang H, Lin JJ, Su ZZ, et al. Subtraction hybridization identifies a novel melanoma differentiation associated gene, mda-7, modulated during human melanoma differentiation,growth and progression. Oncogene 1995;11(12): 2477-2486
4. Chinese source.
5. Chinese source.
6. Feugate JE, Wong L, Li QJ, et al. The CXC chemokine cCAF stimulates precocious deposition of ECM molecules by wound fibroblasts, accelerating development of granulation tissue. BMC Cell Biol 2002;3(5): 13
7. Teofoil P, Barduagni S, Ribuffo M, et al. Expression of Bcl-2,P53,c-jun and c-fos protooncogenes in keloid and hypertrophic scars. J Dematol Sci 1999;22(1):31-37
8. Caudell EG, Mumm JB, Poindexter N, et al. The protein product of the tumor suppressor gene, melanoma differentiation-associated gene 7, exhibits immunostimulatory activity and is designated IL-24. J Immunol 2002;168(12):6041-6046
9. Garn H, Schmidt A, Grau V, et al. IL-24 is expressed by rat and human macrophages. Immunobiology 2002;205(3):321-334
10. Chen JY, Chada S, Mhashikar A, et al. Tumor suppressor MDA-7/IL-24 selectively inhibits vascular smooth muscle cell growth and migration. Mol Ther 2003;8(2):220-229
11. Soo C, Shaw WW, Freymiller E, et al. Cutaneous rat wounds express c49a, a novel gene with homology to the human melanoma differentiation associated gene, mda-7. J Cell Biochem 1999;74(1):1-10
12. Harty M, Neff AW, King MW, et al. Regeneration or scarring: an immunologic perspective. Dev Dyn 2003;226(2):268-279
13. Niessen FB, Schalkwijk J, Vos H, et al. Hypertrophic scar formation is associated with an increased number of epidermal Langerhans cells. J Pathol 2004;202(1):121-129
14. Tong A W, Nemunaitis J, Su D, et al. Intratumoral injection of INGN 241, a nonreplicating adenovector expressing the melanoma-differentiation associated gene-7(mda-7/IL24): biologic outcome in advanced cancer patients. Molec Ther 2005;11(1):160-172
15. Ramesh R, Ito I, Gopalan B, et al. Ectopic production of MDA-7/IL-24 inhibits invasion and migration of human lung cancer cells. Molec Ther 2004;9(4):510-518
16. Nishikawa T, Ramesh R, Munshi A, et al. Adenovirus-mediated mda-7 (IL-24) gene therapy suppresses angiogenesis and sensitizes NSCLC xenograft tumors to radiation. Molec Ther 2004;9(6):818-828
17. Sieger KA, Mhashilkar AM, Stewart A, et al. The tumor suppressor activity of MDA-7/IL-24 is mediated by intracellular protein expression in NSCLC cells. Mol Ther 2004;9(3):355-367
18. Zhao L, Gu J, Dong A, et al. Potent antitumor activity of oncolytic adenovirus expressing mda-7/IL-24 for colorectal cancer. Hum Gene Ther 2005;16(7):845-858
19. Saito Y, Miyahara R, Gopalan B, et al. Selective induction of cell cycle arrest and apoptosis in human prostate cancer cells through adenoviral transfer of the melanoma differentiation-associated-7 (mda-7)/ interleukin-24 (IL-24) gene. Cancer Gene Ther 2005;12(3):238-247
20. Pataer A, Vorburgerm S A, Chada S, et al. Melanoma differentiation-associated gene-7 protein physically associates with the double-stranded RNA-activated protein kinase PKR. Molec Ther 2005;11(5):717-723
21. Gopalan B, Litvak A, Sharma S, et al. Activation of the Fas-FasL signaling pathway by MDA-7/IL-24 kills human ovarian cells. Cancer Res 2005;65(8): 3017-3024