Mapping genetic polymorphisms affecting natural variation in Drosophila longevity

Methods in Molecular Biology

Volumn 371, Issue , 2007, Pages 307-320

  De Luca, Maria ^a   Leips, Jeff ^a  

^a NONE

Author keywords

Chromosome substitution lines; Deficiency stocks; Linkage disequilibrium mapping; Quantitative complementation test; Single nucleotide polymorphisms

Indexed keywords

ANIMAL; CHROMOSOME MAP; DROSOPHILA MELANOGASTER; GENE; GENE LINKAGE DISEQUILIBRIUM; GENETIC POLYMORPHISM; LONGEVITY; MUTATION; QUANTITATIVE TRAIT LOCUS; REVIEW;

ANIMALS; CHROMOSOME MAPPING; DROSOPHILA MELANOGASTER; GENES, INSECT; LINKAGE DISEQUILIBRIUM; LONGEVITY; MUTATION; POLYMORPHISM, GENETIC; QUANTITATIVE TRAIT LOCI;

EID: 34548706517     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1385/1-59745-361-7:307     Document Type: Article

References (16)

1. Guarente, L. and Kenyon, C. (2000) Genetic pathways that regulate ageing in model organisms. Nature 408, 255-262.
2. Finch, C. E. and Ruvkun, G. (2001) The genetics of aging. Annu. Rev. Genomics Hum. Genet. 2, 435-462.
3. Gems, D. and Partridge, L. (2001) Insulin/IGF signalling and ageing: seeing the bigger picture. Curr. Opin. Genet. Dev. 11, 287-292.
4. Finch, C. E. and Tanzi, R. E. (1997) Genetics of aging. Science 278, 407-411.
5. Mackay T. F. C. (2004) The genetic architecture of quantitative traits: lessons from Drosophila. Curr. Opin. Genet. Dev. 14, 253-257.
6. Long, A. D., Mullaney, S. L., Mackay, T. F. C., and Langley, C. H. (1996) Genetic interactions between naturally occurring alleles at quantitative trait loci and mutant alleles at candidate loci affecting bristle number in Drosophila melanogaster. Genetics 144, 1497-1510.
7. Parks, A. L., Cook, K. R., Belvin, M., et al. (2004) Systematic generation of high-resolution deletion coverage of the Drosophila melanogaster genome. Nat. Genet. 36, 288-292.
8. Blenau, W. and Baumann, A. (2001) Molecular and pharmacological properties of insect bioamine receptors: lessons from Drosophila melanogaster and Apis mellifera. Arch. Insect. Biochem. Phys. 48, 13-38.
9. De Luca, M., Roshina, N. V., Geiger-Thornsberry, G. L, Lyman, R. F., Pasyukova, E. G., and Mackay, T. R C. (2003) Dopa decarboxylase affects variation in Drosophila longevity. Nat. Genet. 34, 429-433.
10. Lyman, R. F., Lawrence, F., Nuzhdin, S. V., and Mackay, T. F. C. (1996) Effects of single P element insertions on bristle number and viability in Drosophila melanogaster. Genetics 143, 277-292.
11. Greenspan, R. J. (1997) A kinder, gentler genetic analysis of behavior: dissection gives way to modulation. Curr. Opin. Neurobiol. 7, 805-811.
12. Ronaghi, M., Uhlén, M., and Nyrén, P. (1998) Sequencing method based on realtime pyrophosphate. Science 281, 363-365.
13. Stam, L. R and Laurie, C. C. (1996) Molecular dissection of a major gene effect on a quantitative trait: the level of alcohol deydrogenase expression in Drosophila melanogaster. Genetics 144, 1559-1564.
14. Pasyukova, E. G., Vieira C., and Mackay, T. F. C. (2000) Deficiency mapping of quantitative trait loci affecting longevity in Drosophila melanogaster. Genetics 156, 1129-1146.
15. Leips, J. and Mackay, T. F. (2000) Quantitative trait loci for life span in Drosophila melanogaster: interactions with genetic background and larval density. Genetics 155, 1773-1788.
16. th edition. Prentice Hall, NJ.