Molecular and functional characterization of EhPAK3, a p21 activated kinase from Entamoeba histolytica

Gene

Volumn 402, Issue 1-2, 2007, Pages 57-67

  Dutta, Suman ^a   Sardar, Anupama ^a   Ray, Doel ^a   Raha, Sanghamitra ^a  

^a SAHA INSTITUTE OF NUCLEAR PHYSICS   (India)

Author keywords

Capping; Entamoeba histolytica; p21 Activated kinase (PAK); Phylogeny; Sequence

Indexed keywords

CONCANAVALIN A; GUANOSINE TRIPHOSPHATASE; HISTONE H1; MYOSIN; P21 ACTIVATED KINASE; P21 ACTIVATED KINASE 3; PLECKSTRIN; RECOMBINANT PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; AUTOPHOSPHORYLATION; CAPPING PHENOMENON; CARBOXY TERMINAL SEQUENCE; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOPLASM; DICTYOSTELIUM DISCOIDEUM; ENTAMOEBA HISTOLYTICA; ENZYME LOCALIZATION; HEAVY CHAIN; IN VITRO STUDY; MOLECULAR DYNAMICS; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYLOGENY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION;

AMINO ACID SEQUENCE; ANIMALS; CELLS, CULTURED; ENTAMOEBA HISTOLYTICA; IMMUNOPRECIPITATION; INTRONS; MOLECULAR SEQUENCE DATA; OPEN READING FRAMES; P21-ACTIVATED KINASES; PHYLOGENY; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT;

DICTYOSTELIUM DISCOIDEUM; ENTAMOEBA HISTOLYTICA;

EID: 34548694298     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gene.2007.07.022     Document Type: Article

References (37)

1. Arhets P., Gounon P., Sansonetti P., and Guillen N. Myosin II is involved in capping and uroid formation in the human pathogen Entamoeba histolytica. Infect. Immun. 63 (1995) 4358-4367
2. Arias-Romero L., et al. EhPAK2, a novel p21-activated kinase, is required for collagen invasion and capping in Entamoeba histolytica. Mol. Biochem. Parasitol. 149 (2006) 17-76
3. Banerjee S., Sen A., Das P., and Saha P. Leishmania donovani cyclin 1 (LdCyc1) forms a complex with cell cycle kinase subunit CRK3 (LdCRK3) and is possibly involved in S-phase-related activities. FEMS Microbiol. Lett. 256 (2006) 75-82
4. Benton B.K., Tinkelenberg A., Gonzalez I., and Cross F.R. Cla4p, a Saccharomyces cerevisiae Cdc42p-activated kinase involved in cytokinesis, is activated at mitosis. Mol. Cell. Biol. 17 (1997) 5067-5076
5. Bapteste E., et al. The analysis of 100 genes supports the grouping of three highly divergent amoebae: Dictyostelium, Entamoeba, and Mastigamoeba. Proc. Natl. Acad. Sci. U. S. A. 99 (2002) 1414-1419
6. Bokoch G.M. Biology of the p21-activated kinases. Ann. Rev. Biochem. 72 (2003) 743-781
7. Brezska H., Young R., Tan C., Szczepanowska J., and Korn E.D. Calmodulin-binding and autoinhibitory domains of Acanthamoeba myosin I heavy chain kinase, a p21-activated kinase (PAK),. J. Biol. Chem. 276 (2001) 47468-47473
8. Cavalier-Smith T. A revised six-kingdom system of life. Biol. Rev. Cambridge Philos. Soc. 73 (1998) 203-266
9. Chomczynski P., and Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162 (1987) 156-159
10. Chong C.L., Tan L.L., Lim L., and Manser E. The mechanism of PAK activation. Autophosphorylation events in both regulatory and kinase domains control activity. J. Biol. Chem. 276 (2001) 17347-17353
11. Chung C.Y., and Firtel R.A. PAKa, a putative PAK family member. J. Cell Biol. 147 (1999) 559-576
12. Dan I., Watanabe N.M., and Kusumi A. The Ste20 group kinases as regulators of MAP kinase cascades. Trends Cell Biol. 11 (2001) 220-230
13. Diamond L.S., Harlow D.R., and Cunnick C.C. A new medium for the axenic cultivation of Entamoeba histolytica and other Entamoeba. Trans. R. Soc. Trop. Med. Hyg. 72 (1978) 431-432
14. Edlind T.D., Li J., Visvesvara G.S., Vodkin M.H., Mclaughlin G.L., and Katiyar S.K. Phylogenetic analysis of beta-tubulin sequences from amitochondrial protozoa. Mol. Phylogenet. Evol. 5 (1996) 359-367
15. Franco-Barraza J., Zamudio-Meza H., Franco E., Dominguez-Robles M.C., Villegas-Sepulveda N., and Meza I. Rho signaling in Entamoeba histolytica modulates actomyosin-dependent activities stimulated during invasive behavior. Cell Motil. Cytoskeleton 63 (2006) 117-131
16. Felsenstein J. Phylip-phylogeny Inference Package (Version 3.2). Cladistics 5 (1989) 164-166
17. Ghosh S.K., and Samuelson J. Involvement of p21racA, phosphoinositide 3 kinase, and vacuoler ATPase in phagocytosis of bacteria and erythrocytes by Entamoeba histolytica: suggestive evidence for coincidental evolution of amebic invasiveness. Infect. Immun. 65 (1997) 4243-4249
18. Godbold G.D., and Mann B.J. Cell killing by the human parasite Entamoeba histolytica is inhibited by the rho-inactivating C3 exoenzyme. Mol. Biochem. Parasitol. 108 (2000) 147-151
19. Guillen N., Boquet P., and Sansonetti P. The small GTP-binding protein RacG regulates uroid formation in the protozoan parasite Entamoeba histolytica. J. Cell Sci. 111 (1998) 1729-1739
20. Hanks S.K., and Quinn A.M. Protein kinase catalytic domain sequence database: identification of conserved features of primary structure and classification of family members. Methods Enzymol. 200 (1991) 38-62
21. Hoffman C., Shepelev M., and Chernoff J. The genetics of Pak. J. Cell. Sci. 117 (2004) 4343-4354
22. Labruyere E., Zimmer C., Galy V., Olivo-Marin J.C., and Guillen N. EhPAK, a member of the p21-activated kinase family, is involved in the control of Entamoeba histolytica migration and phagocytosis. J. Cell Sci. 116 (2003) 61-71
23. Labruyere E., and Guillen N. The cytoskeleton of Entamoeba histolytica: structure, function, and regulation by signaling pathways. Arch. Med. Res. 37 (2006) 253-258
24. Lee S.F., Egelhof T.T., Mahasneh A., and Cote G.P. Cloning and characterization of a Dictyostelium myosin I heavy chain kinase activated by Cdc42 and Rac. J. Biol. Chem. 271 (1996) 27044-27048
25. Lee S., Rivero F., Park K.C., Huang E., Funamoto S., and Firtel R.A. Dictyostelium PAKc is required for proper chemotaxis. Mol. Biol. Cell 15 (2004) 5456-5469
26. Lockhead P.A., Sibbet G., Morrice N., and Cleghon V. Activation-loop autophosphorylation is mediated by a novel transitional intermediate form of DYRKs. Cell 121 (2005) 925-936
27. Mentzel B., and Raabe T. Phylogenetic and structural analysis of the Drosophila melanogaster p-21activated kinase DmPAK3. Gene 349 (2005) 25-33
28. Meza I., Talamas-Rohana P., and Vargas M.A. Host tissue invasion by Entamoeba histolytica is powered by motility and phagocytosis. Arch. Med. Res. 37 (2006) 234-243
29. Oganesyan N., Kim S.H., and Kim R. On-column protein refolding for crystallization. J. Struct. Funct. Genomics 6 (2005) 177-182
30. Ray D., Dutta S., Banerjee S., Banerjee R., and Raha S. Identification, structure, and phylogenetic relationships of a mitogen-activated protein kinase homologue from the parasitic protist Entamoeba histolytica. Gene 346 (2005) 41-50
31. Saito-Nakano Y., Nakazawa M., Shigeta Y., Takeuchi T., and Nozaki T. Identification and characterization of genes encoding novel Rab proteins from Entamoeba histolytica. Mol. Biochem. Parasitol. 116 (2001) 219-222
32. 2 treatment through enhancement of mRNA stability. FEBS Lett. 579 (2005) 4402-4406
33. Tavares P., Sansonetti P., and Guillen N. Cell polarization and adhesion in a motile pathogenic protozoan: role and fate of the Entamoeba histolytica Gal/GalNAc lectin. Microbiol. Infect. 2 (2000) 643-649
34. Tavares P., Sansonetti P., and Guillen N. The interplay between receptor capping and cytoskeleton remodeling in Entamoeba histolytica. Arch. Med. Res. 31 (2000) S140-S142
35. Thompson J.D., Gibson T.J., Plewniak F., Jeanmougin F., and Higgins D.G. The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res. 24 (1997) 4876-4882
36. Wilson K., Collart F.R., Huberman E., Stringer J.R., and Ullman B. Amplification and molecular cloning of the IMP dehydrogenase gene of Leishmania donovani. J. Biol. Chem. 266 (1991) 1665-1671
37. Zhao Z., and Manser E. PAK and other Rho-associated kinases-effectors with surprisingly diverse mechanisms of regulation. Biochem. J. 386 (2005) 201-214