Postnatal cardiopulmonary adaptations to high altitude

Respiratory Physiology and Neurobiology

Volumn 158, Issue 2-3, 2007, Pages 190-203

  Huicho, Luis ^a,b,c  

^a UNIVERSIDAD NACIONAL MAYOR DE SAN MARCOS   (Peru)

^b UNIVERSIDAD PERUANA CAYETANO HEREDIA   (Peru)

^c INSTITUTO NACIONAL DE SALUD DEL NIÑO   (Peru)

Author keywords

Cardiopulmonary adaptations; High altitude; Postnatal

Indexed keywords

ALTITUDE ACCLIMATIZATION; ARTERIAL OXYGEN SATURATION; ARTICLE; CARDIOPULMONARY FUNCTION; HEART RIGHT VENTRICLE; HUMAN; HYPOXIA; LUNG ARTERY PRESSURE; LUNG FUNCTION; LUNG VENTILATION; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PULMONARY HYPERTENSION;

ACCLIMATIZATION; AGE FACTORS; ALTITUDE; ANIMALS; ANOXIA; ATMOSPHERIC PRESSURE; BLOOD PRESSURE; CARDIOVASCULAR SYSTEM; CHILD, PRESCHOOL; HEMOGLOBINS; HUMANS; INFANT; OXYGEN; PULMONARY GAS EXCHANGE; PULMONARY VENTILATION;

EID: 34548688728     PISSN: 15699048     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.resp.2007.05.004     Document Type: Article

References (100)

1. Alzamora Castro V., Battilana G., Abugattas R., and Sialer S. Patent ductus arteriosus and high altitude. Am. J. Cardiol. 5 (1960) 761-763
2. Aparicio O.O., Romero Gutierrez F., Harris P., and Anand I. Echocardiography shows persistent thickness of the wall of the right ventricle in infants at high altitude. Cardioscience 2 (1991) 63-69
3. Ballew C., and Haas J.D. Hematologic evidence of fetal hypoxia among newborn infants at high altitude in Bolivia. Am. J. Obstet. Gynecol. 155 (1986) 166-169
4. In: Barker D.J.P. (Ed). Fetal and Infant Origins of Adult Disease (2002), BMJ Books, London
5. Beall C.M. Tibetan and Andean patterns of adaptation to high-altitude hypoxia. Hum. Biol. 72 (2000) 201-228
6. Beall C.M. Andean, Tibetan, and Ethiopian patterns of adaptation to high-altitude hypoxia. Integr. Comp. Biol. 46 (2006) 18-24
7. Beall C.M., Blangero J., Williams-Blangero S., and Goldstein M.C. A major gene for percent of oxygen saturation of arterial hemoglobin in Tibetan highlanders. Am. J. Phys. Anthropol. 95 (1994) 271-276
8. Beall C.M., Decker M.J., Brittenham G.M., Kushner I., Gebremedhin A., and Strohl K.P. An Ethiopian pattern of human adaptation to high-altitude hypoxia. Proc. Natl. Acad. Sci. 99 (2002) 17215-17228
9. Beall C.M., Song K., Elston R.C., and Goldstein M.C. Higher offspring survival among Tibetan women with high oxygen saturation genotypes residing at 4000 m. Proc. Nat. Acad. Sci. 101 (2004) 14300-14304
10. Beall C.M., Strohl K., Blangero J., Williams-Blangero S., Brittenham G.M., and Goldstein M.C. Quantitative genetic analysis of arterial oxygen saturation in Tibetan highlanders. Hum. Biol. 69 (1997) 597-604
11. Blanco L.N., Massaro D., and Massaro G.D. Alveolar size, number, and surface area: developmentally dependent response to 13% O2. Am. J. Physiol. Lung. Cell. Mol. Physiol. 261 (1991) L370-L377
12. Brutsaert T.D. Limits on inferring genetic adaptation to high altitude in Himalayan and Andean populations. High Alt. Med. Biol. 2 (2001) 211-225
13. Cohen G., Malcolm G., and Henderson-Smart D. Ventilatory response of the newborn infant to mild hypoxia. Pediatr. Pulmonol. 24 (1997) 163-172
14. Cohen G., and Katz-Salamon M. Development of chemoreceptor responses in infants. Respir. Physiol. Neurobiol. 149 (2005) 233-242
15. Duke T., Mgone J., and Frank D. Hypoxemia in children with severe pneumonia in Papua New Guinea. Int. J. Tuberc. Lung Dis. 5 (2001) 511-519
16. Duke T., Blaschke A.J., Sialis S., and Bonkowsky J.L. Hypoxaemia in acute respiratory and non-respiratory illnesses in neonates and children in a developing country. Arch. Dis. Child. 86 (2002) 108-112
17. Dyke T., Lewis D., Heegaard W., Manary M., Flew S., and Rudeen K. Predicting hypoxia in children with acute lower respiratory infection: a study in the highlands of Papua New Guinea. J. Trop. Pediatr. 41 (1995) 196-201
18. Easton P.A., Slykerman L.J., and Anthonisen N.A. Recovery of the ventilatory response to hypoxia in normal adults. J. Appl. Physiol. 64 (1988) 521-528
19. Eber E., and Zach M.S. Paediatric origins of adult lung disease: long term sequelae of bronchopulmonary dysplasia (chronic lung disease of infancy). Thorax 56 (2000) 317-323
20. Frisancho A.R. Growth and development at high altitude. In: Baker P.T., and Little M.A. (Eds). Man in the Andes. A Multidisciplinary Study of High-altitude Quechua (1976), Dowden and Hutchinson, Stroudsburg, PA 180-207
21. Frisancho A.R. Human growth and pulmonary function of a high altitude Peruvian Quechua population. Hum. Biol. 41 (1969) 365-379
22. Galarza Guzman C.M. Hemoglobinas en recién nacidos "ciudad de La Paz altura 3600 m". Commun. Rápida Instit. Boliv. Biolog. Alt. 2 (1988) 3-16
23. Gamboa R., and Marticorena E. Presión arterial pulmonar en recién nacidos en las grandes alturas. Arch. Instit. Biolog. Andina 4 (1971) 55-66
24. Gamponia M.J., Babaali H., Yugar F., and Gilman R.H. Reference values for pulse oximetry at high altitude. Arch. Dis. Child. 78 (1998) 461-465
25. Greksa L.P. Chest morphology of young Bolivian high-altitude residents of European ancestry. Hum. Biol. 58 (1986) 427-443
26. Greksa L.P. Effect of altitude on the stature, chest depth and forced vital capacity of low-to-high altitude migrant children of European ancestry. Hum. Biol. 60 (1988) 23-32
27. Greksa L.P., Spielvogel H., Caceres E., and Paredes-Fernández L. Lung function of young Aymara highlanders. Ann. Hum. Biol. 14 (1987) 533-542
28. Greksa L.P., Spielvogel H., Paz-Zamora M., Caceres E., and Paredes-Fernández L. Effect on the lung function of high altitude residents of European ancestry. Am. J. Phys. Anthropol. 75 (1988) 77-85
29. Grover R.F., Vogel J.H., Voigt G.C., and Blount Jr. S.G. Reversal of high altitude pulmonary hypertension. Am J Cardiol. 18 (1966) 928-932
30. Hafstrom O., Milerad J., Sandberg K.L., and Sundell H.W. Cardiorespiratory effects of nicotine exposure during development. Respir. Physiol. Neurobiol. 149 (2005) 325-341
31. Harding R., Cock M.L., Louey S., Joyce B.J., Davey M.G., Albuquerque C.A., Hooper S.B., and Maritz G.S. The compromised intra-uterine environment: implications for future lung health. Clin. Exp. Pharmacol. Physiol. 27 (2000) 965-974
32. Hochachka P.W. Defense strategies against hypoxia and hypothermia. Science 231 (1986) 234-241
33. Hochachka P., Gunga H.C., and Kirsch K. Our ancestral physiological phenotype: and adaptation for hypoxia tolerance or for endurance performance?. Proc. Natl. Acad. Sci. 95 (1998) 1915-1920
34. Hochachka P.W., and Lutz P.L. Mechanism, origin, and evolution of anoxia tolerance in animals. Comp. Biochem. Physiol. B: Biochem. Mol. Biol. 130 (2001) 435-459
35. Holt P.G., and Sly P.D. Paediatric origins of adult lung diseases: Prevention of adult asthma by early intervention during childhood: potential value of new generation immunomodulatory drugs. Thorax 55 (2000) 700-703
36. Huicho L. Hypoxaemia in children: "abnormal" values may be misleading. Arch. Dis. Child. 88 (2003) 364
37. Huicho L., Muro M., Pacheco A., Silva J., Gloria E., Marticorena E., and Niermeyer S. Cross-sectional study of echocardiographic characteristics in healthy children living at high altitude. Am. J. Hum. Biol. 17 (2005) 704-717
38. Huicho L., and Niermeyer S. Cardiopulmonary pathology among children resident at high altitude in Tintaya, Peru: a cross-sectional study. High Alt. Med. Biol. 7 (2006) 168-179
39. Huicho L., Pawson I.G., Leon-Velarde F., Rivera-Chira M., Pacheco A., Muro M., and Silva J. Oxygen saturation and heart rate in healthy school children and adolescents living at high altitude. Am. J. Hum. Biol. 13 (2001) 761-770
40. Huicho L., and Niermeyer S. Cross-sectional study of electrocardiographic pattern in healthy children resident at high altitude. Am. J. Phys. Anthropol. 133 (2007) 879-886
41. Hulme C.W., Ingram T.E., and Lonsdale-Eccles D.A. Electrocardiographic evidence for right heart strain in asymptomatic children living in Tibet-a comparative study between Han Chinese and ethnic Tibetans. Wilderness Environ. Med. 14 (2003) 222-225
42. Hurtado Gomez L., and Calderon R.G. Hipoxia de altura en la insuficiencia cardiaca del lactante. Bolet. Soc. Boliv. Pediatr. IX (1965) 11-23
43. Joseph V., Soliz J., Pequignot J., Sempore B., Cottet-Emard J.M., Dalmaz Y., Favier R., Spielvogel H., and Pequignot J.M. Gender differentiation of the chemoreflex chemoreflex during growth at high altitude: functional and neurochemical studies. Am. J. Phys. Regul. Integrative Comp. Biol. 278 (2000) R806-R816
44. Khoury G.H., and Hawes C.R. Primary pulmonary hypertension in children living at high altitude. J. Pediatr. 62 (1963) 177-185
45. Kummeling I., Stelma F.F., Dagnelie P.C., Snijders B.E., Penders J., Huber M., van Ree R., van den Brandt P.A., and Thijs C. Early life exposure to antibiotics and the subsequent development of eczema, wheeze, and allergic sensitization in the first 2 years of life: the KOALA Birth Cohort Study. Pediatrics 119 (2007) e225-e231
46. Lahiri S., Brody J.S., Motoyama E.D., and Velasquez T.M. Regulation of breathing in newborns at high altitude. J. Appl. Physiol. 44 (1978) 673-678
47. Le Cras T.D., Markham N.E., Morris K.G., Ahrens C.R., McMurtry I.F., and Abman S.H. Neonatal dexamethasone treatment increases the risk for pulmonary hypertension in adult rats. Am. J. Physiol. Lung Cell. Mol. Physiol. 278 (2000) L822-L829
48. Le Cras T.D., Hardie W.D., Deutsch G.H., Albertine K.H., Ikegami M., Whitsett J.A., and Korfhagen T.R. Transient induction of TGF-α disrupts lung morphogenesis, causing pulmonary disease in adulthood. Am. J. Physiol. Lung Cell. Mol. Physiol. 287 (2004) L718-L729
49. Leon-Velarde F., Maggiorini M., Reeves J.T., Aldashev A., Asmus I., Bernardi L., Ge R.L., Hackett P., Kobayashi T., Moore L.G., Penaloza D., Richalet J.P., Roach R., Wu T., Vargas E., Zubieta-Castillo G., and Zubieta-Calleja G. Consensus statement on chronic and subacute high altitude diseases. High Alt. Med. Biol. 6 (2005) 147-157
50. Le Souëf P.N. Paediatric origins of adult lung diseases: tobacco related lung diseases begin in childhood. Thorax 55 (2000) 1063-1067
51. Lozano J.M. Epidemiology of hypoxaemia in children with acute lower respiratory infection. Int. J. Tuber. Lung Dis. 5 (2001) 496-504
52. Lozano J.M., Steinhoff M., Ruiz J.G., Mesa M.L., Martinez N., and Dussan B. Clinical predictors of acute radiological pneumonia and hypoxaemia at high altitude. Arch. Dis. Child. 71 (1994) 323-327
53. Lin C.P., and Wu T.Y. Clinical analysis of 286 cases of pediatric high altitude heart diseases. Chin. Med. J. 54 Engl suppl to No. 6 (1974) 99-100
54. Maritz G.S., Morley C.J., and Harding R. Early developmental origins of impaired lung structure and function. Early Hum. Dev. 81 (2005) 763-771
55. Marsden P.A., Heng H.H.Q., Scherer S.W., Stewart R.J., Hall A.V., Shi X.M., Tsui L.C., and Schappert K.T. Structure and chromosomal localization of the human constitutive endothelial nitric oxide synthase gene. J. Biol. Chem. 268 (1993) 17478-17488
56. Marticorena E.A. Observaciones desde el nacimiento hasta los 14 anos de edad, en alturas comprendidas entre los 3730m y 4710msnm y sus implicancias en la adultez y enfermedad. Arch. Instit. Biol. Andina 12 (1983) 26-50
57. Massaro G., and DeCarlo Masaro G. Critical period for alveologenesis and early determinants of adult pulmonary disease. Am. J. Physiol. Lung Cell. Mol. Physiol. 287 (2004) 715-717
58. Massaro G.D., Olivier J., and Massaro D. Short-term perinatal 10% O2 alters postnatal development of lung alveoli. Am. J. Physiol. 257 (1989) L221-L225
59. 2 and a critical period. Am. J. Physiol. Lung Cell. Mol. Physiol. 258 (1990) L321-L327
60. Miao C.Y., Li W.X., Geng D., Tao L.A., Zuberbuhler J.S., and Zuberbuhler J.R. Effect of high altitude on prevalence of congenital heart disease. Chin. Med. J. (Engl). 101 (1988) 415-418
61. Monge C. Acclimatization in the Andes. Reissued 1948 edition (1978), The Johns Hopkins Press, Baltimore
62. Monge C., and Leon-Velarde F. Physiological adaptation to high altitude: oxygen transport in mammals and birds. Physiol. Rev. 71 (1991) 1135-1172
63. Moore L.G. Human genetic adaptation to high altitude. High Alt. Med. Biol. 2 (2001) 257-279
64. Mortola J.P., Frappell P.B., Frappell D.E., Villena-Cabrera N., Villena-Cabrera M., and Pena F. Ventilation and gaseous metabolism in infants born at high altitude, and their responses to hyperoxia. Am. Rev. Respir. Dis. 146 (1992) 1206-1209
65. Moudgil R., Michelakis E.D., and Archer S.L. Hypoxic pulmonary vasoconstriction. J. Appl. Physiol. 98 (2005) 390-403
66. Mueller W., Yen F., Rothhammer F., and Schull F. A multinational Andean genetic and health program. VI. Physiological measurements of lung function in an hypoxic environment. Hum. Biol. 50 (1978) 489-513
67. Niermeyer S. Cardiopulmonary transition in the high altitude infant. High Alt. Med. Biol. 4 (2003) 225-239
68. Niermeyer S., Shaffer E.M., and Moore L.G. Impaired cardiopulmonary transition at high altitude. Pediatr. Res. 43 (1998) 292A
69. Niermeyer S., Andrade P., Vargas E., and Moore L.G. Prolonged postnatal cardiopulmonary transition at 3700-4000 m. High Alt. Med. Biol. 3 (2002) 439
70. Niermeyer S., Yang P., Shanmina D., Zhuang J., and Moore L.G. Arterial oxygen saturation in Tibetan and Han infants born in Lhasa, Tibet. N. Engl. J. Med. 333 (1995) 1248-1252
71. Niermeyer S., Shaffer E.M., Thilo E., Corbin C., and Moore L.G. Arterial oxygenation and pulmonary arterial pressure in healthy neonates and infants at high altitude. J. Pediatr. 123 (1993) 767-772
72. Onyango F.E., Steinhoff M.C., Wafula E.M., Wariua S., Musia J., and Kitonyi J. Hypoxaemia in young Kenyan children with acute lower respiratory infection. BMJ 306 (1993) 612-615
73. Pawson I.G., Huicho L., Muro M., and Pacheco A. Growth of children in two economically diverse Peruvian high-altitude communities. Am. J. Hum. Biol. 13 (2001) 323-340
74. Pearson D.L., Dawling S., Walsh W.F., Haines J.L., Christman B.W., Bazyk A., Scott N., and Summar M.L. Neonatal pulmonary hypertension: Urea-cycle intermediates, nitric oxide production, and carbamoyl-phosphate synthetase function. N. Engl. J. Med. 344 (2001) 1832-1838
75. Peñaloza D., Arias-Stella J., Sime F., Recavarren S., and Marticorena E. The heart and pulmonary circulation in children at high altitudes: physiological, anatomical and clinical observations. Pediatrics 34 (1964) 568-582
76. Peñaloza D., Gamboa R., Dyer J., Echevarria M., and Marticorena E. The influence of high altitudes on the electrical activity of the heart. I. Electrocardiographic and vectorcardiographic observations in the newborn, infants, and children. Am. Heart J. 59 (1960) 111-128
77. Peñaloza D., Gamboa R., Marticorena E., Echevarria M., Dyer J., and Gutiérrez E. The influence of high altitudes on the electrical activity of the heart. Electrocardiographic and vectorcardiographic observations in adolescence and adulthood. Am. Heart J. 61 (1961) 101-115
78. Reuland D.S., Steinhoff M.C., Gilman R.H., and Bara M. Prevalence and prediction of hypoxemia in children with respiratory infections in the Peruvian Andes. J. Pediatr. 119 (1991) 900-906
79. Robinson P. Paediatric origins of adult lung disease: Cystic fibrosis. Thorax 56 (2000) 237-241
80. Rupert J.L., and Hochachka P.W. Genetic approaches to understanding human adaptation to altitude in the Andes. J. Exp. Biol. 204 (2001) 3151-3160
81. Rupert J.L., and Hochachka P.W. The evidence for hereditary factors contributing to high altitude adaptation in Andean natives: a review. High Alt. Med. Biol. 2 (2001) 235-256
82. Saldaña M., and Arias-Stella J. Studies on the structure of the pulmonary trunk. I. Normal changes in the elastic configuration of the human pulmonary trunk at different ages. Circulation 27 (1963) 1086-1093
83. Saldaña M., and Arias-Stella J. Studies on the structure of the pulmonary trunk. II. The evolution of the elastic configuration of the pulmonary trunk in people native to high altitudes. Circulation 27 (1963) 1094-1100
84. Scheid P., and Piiper J. Vertebrate respiratory physiology. In: Dantzler W.H. (Ed). Comparative Physiology. Section 13, vol. 1 (1997), American Physiological Society, Oxford, New York 309-356
85. Sime F., Banchero N., Peñaloza D., Gamboa R., Cruz J., and Marticorena E. Pulmonary hypertension in children born and living at high altitudes. Am. J. Cardiol. 11 (1963) 143-149
86. Skovgaard N., and Wang T. Local control of pulmonary blood flow and lung structure in reptiles: implications for ventilation perfusion matching. Respir. Physiol. Neurobiol. 154 (2006) 107-117
87. Sly P.D. Paediatric origins of adult lung disease: introduction. Thorax 55 (2000) 585-586
88. Stick S. Paediatric origins of adult lung disease: the contribution of airway development to paediatric and adult lung disease. Thorax 55 (2000) 587-594
89. Stinson S. Chest dimensions of European and Aymara children at high altitude. Ann. Hum. Biol. 12 (1985) 333-338
90. Sui G.J., Liu Y.H., Cheng X.S., Anand I.S., Harris E., Harris P., and Heath D. Subacute infantile mountain sickness. J. Pathol. 155 (1988) 161-170
91. Svanes C., Omenaas E., Jarvis D., Chinn S., Gulsvik, and Burney P. Parental smoking in childhood and adult obstructive lung disease: results from the European Community Respiratory Health Survey. Thorax 4 (2004) 295-302
92. Tucker A., and Rhodes J. Role of vascular smooth muscle in the development of high altitude pulmonary hypertension: an interspecies evaluation. High Alt. Med. Biol. 2 (2001) 173-189
93. Victoria-Oliva G., Mojarro-Rios J., Alva-Espinosa C., Villasis-Keever M., Labarthe-Cabrera J., Arellano-Penagos M., Velasco-Jimenez S., Alarcon-Santos S., Muro R., and Diaz-Arauzo A. Ecocardiografia Doppler en recién nacidos con riesgo de hipertensión arterial pulmonar. Revista Mex. Cardiol. 7 (1996) 25-31
94. von Mutius E. Paediatric origins of adult lung disease: paediatric origins of adult lung disease. Thorax 56 (2000) 153-157
95. Warner J.A. Primary sensitization in infants. Ann. Allergy Asthma Immunol. 83 (1999) 426-430
96. Weiss K.M. Genetic variation and human disease. Principles and Evolutionary Approaches (1993), Cambridge University Press, Cambridge
97. Winslow R.M., and Monge C.C. Hypoxia, Polycythemia, and Chronic Mountain Sickness (1978), The Johns Hopkins Press, Baltimore
98. Wu T.Y., and Miao C.Y. High altitude heart disease in children in Tibet. High. Alt. Med. Biol. 3 (2002) 323-325
99. Wu T.Y., Miao C.Y., Lin C., Ma R., Yao R., and Lian T. Altitude illness in children on the Tibetan plateau. In: Ohno H., Kobayashi T., Masuyama S., and Nakashima M. (Eds). Progress in Mountain Medicine and High Altitude Physiology (1998), Press Committee of the 3rd World Congress on Mountain Medicine and High Altitude Physiology, Matsumoto, Japan 195-200
100. Wu T.Y., Miao C.Y., and Wang X. High altitude heart disease in children in Tibet. In: Viscor G., Ricart A., and Leal C. (Eds). Health & Height: Proceedings of the 5th World Congress on Mountain Medicine and High Altitude Physiology (2003), Universitat de Barcelona, Barcelona, Spain 291-294