Analysis of biological activities from Philodryas olfersii (Lichtenstein) and P. patagoniensis (Girard) venoms (Serpents, Colubridae);Análise das atividades biológicas dos venenos de Philodryas olfersii (Lichtenstein) e P. patagoniensis (Girard) (Serpentes, Colubridae)

Revista Brasileira de Zoologia

Volumn 24, Issue 2, 2007, Pages 410-418

  Da Rocha, Marisa M T ^a   Furtado, Maria De F D ^a  

^a INSTITUTO BUTANTAN   (Brazil)

Author keywords

Local and systemic activities; Toxics secretions; Xenodontinae

Indexed keywords

BOTHROPS; COLUBRIDAE; MUS; PHILODRYAS; PHILODRYAS OLFERSII; PHILODRYAS PATAGONIENSIS; SERPENTES; XENODONTINAE;

EID: 34548684569     PISSN: 01018175     EISSN: None     Source Type: Journal    
DOI: 10.1590/s0101-81752007000200019     Document Type: Article

References (77)

1. ACOSTA, O.; L.C. LEIVA; M.E. PEICHOTO; S. MAKUÑAK; P.T. RUÍZ; C. GAY & L. REY. 2003a. Edematogenic and myotoxic activities of the Duvernoy's gland secretion of Philodryas olfersii from the north-est region of Argentina. BIOCEL 27 (3): 363-370.
2. ACOSTA, O.; L.C. LEIVA; M.E. PEICHOTO; S. MARUÑAK; P. TEBLER & L. REY. 2003b. Hemorrhagic activity of the Duvernoy's gland secretion of the xenodontine colubrid Philodryas patagoniensis from the north-east region of Argentina. Toxicon 41: 1007-1012.
3. AMARAL, A. 1921. Últimos trabalhos inéditos de J. Florencio Gomes: Duas novas espécies de Colubrídeos opisthoglyphos brasileiros (Philodryas oligolepis e Apostolepis longicaudata). Annais Paulista de Medicina e Cirurgia 9 (7/8): 157-221.
4. ARAÚJO, M.E. & A.C.M.C.A. SANTOS. 1997. Cases of human envenoming caused by Philodryas olfersii and Philodryas patagoniensis (Serpentes: Colubridae). Revista da Sociedade Brasileira de Medicina Tropical 30 (6): 517-519.
5. ASSAKURA, M.T.; A.P.N. REICHL & F.R. MANDELBAUM. 1994. Isolation and characterization of five fibrin(ogen)olytic enzymes from the venom of Philodryas olfersii (green snake). Toxicon 32 (7): 819-831.
6. ASSAKURA, M.T.; M.G. SALOMÃO; G. PUORTO& F.R. MANDELBAUM. 1992. Hemorrhagic, fibrinogenolytic and edema-forming activities of the venom of the colubrid snake Philodryas olfersii (green snake). Toxicon 30 (4): 427-438.
7. BJARNASON, J. & J.W. FOX. 1994. Hemorrhagic metalloproteinases from snake venoms. Pharmacology & Therapeutics 62: 325-372.
8. th ed., 425p.
9. CARVALHO, M.A & F. NOGUEIRA. 1998. Serpentes da área urbana de Cuiabá, Mato Grosso: aspectos ecológicos e acidentes ofídicos associados. Cadernos de Saúde Pública 14: 753-763.
10. CHACUR, M.; G. PICOLO; J.M. GUTIÉRREZ; C.F.P. TEIXEIRA & Y. CURY. 2001. Pharmacological modulation of hyperalgesia induced by Bothrops asper (terciopelo) snake venom. Toxicon 39: 1173-1181.
11. CHIPPAUX, J. P.; V. WILLIAMS AND J. WHITE. 1991. Snake venom variability: Methods of study, results and interpretation. Toxicon 29: 1279-1303.
12. FAN, H.W. & J.L. CARDOSO. 1995. Clinical toxicology of snake bites in South America, p. 667-688. In: J. MEIER & J. WHITE (Eds). Handbook of clinical toxicology of animal venoms and poisons. Boca Raton, CRC Press, 752p.
13. FERLAN, I.; A. FERLAN; T. KING & F.E. RUSSELL. 1983. Preliminary studies on the venom of the colubrid snake Rhabdophis subminiatus (red-necked keelback). Toxicon 21 (4): 570-574.
14. rd ed., 333p.
15. FRANÇA, F.O.S. & C.M.S. MÁLAQUE. 2003. Acidente botrópico p. 72-86. In: J.L.C. CARDOSO; F.O.S. FRANÇA; F.H. WEN; C.M.S MÁLAQUE & V. HADDAD JR (Eds). Animais peçonhentos no Brasil: biologia, clínica e terapêutica dos acidentes. São Paulo, Sarvier, FAPESP, 468p.
16. FRANCO, F.L. 2003. Origem e diversidade das serpentes, p. 13-32. In: J.L.C. CARDOSO; F.O.S.FRANÇA; F.H. WEN; C.M.S MÁLAQUE; V. HADDAD JR (Eds). Animais peçonhentos no Brasil: biologia, clínica e terapêutica dos acidentes. São Paulo, Sarvier, FAPESP, 468p.
17. FRY, B.G.; N.G. LUMSDEN; W. WUSTER; J.C. WICKRAMARATNA; W.C. HODGSON & R.M. KINI. 2003a. Isolation of neurotoxin (α-colubritoxin) from a nonvenomous Colubrid: evidence for early origin of venom in snakes. Journal of Molecular Evolution 57: 446-452.
18. FRY, B.G.; W. WÜSTER; S.F.R. RAMJAN; T. JACKSON; P. MARTELLI & M. KINI. 2003b. ANALYSIS OF COLUBROIDEA snake venoms by liquid chromatography with mass spectrometry: evolutionary and toxicological implications. Rapid Communications in Mass Spectrometry 17: 2047-2062.
19. FURTADO, M.F.D.; W. DIAS DA SILVA & G.M.D.D. COLLETO. 1991. Controle de Qualidade dos Venenos Animais e dos Correspondentes Antivenenos. I Padronização dos métodos de ensaio das atividades bioquímicas e farmacológicas dos venenos de algumas espécies do gênero Bothrops e Crotalus usando amostras secas a temperatura ambiente ou liofilizadas. Memórias do Instituto Butantan 53 (2): 149-159.
20. GENÉ, J.A.; A. ROY; G. ROJAS; J.M. GUTIÉRREZ & L. CERDAS. 1989. Comparative study on coagulant, defibrinanting, fibrinolytic and fibrinogenolytic activities of Costa Rican crotaline snake venoms and their neutralization by a polyvalent antivenom. Toxicon 27 (8): 841-848.
21. GUTIÉRREZ, J.M. & A. RUCAVADO. 2000. Snake venom metalloproteinases: their role in the pathogenesis of local tissue damage. Biochimie 82: 841-850.
22. GUTIÉRREZ, J.M. & B. LOMONTE. 2003. Efectos Locales en el Envenenamiento Ofídico en América Latina, p. 310-323. In: J.L.C. CARDOSO; F.O.S.FRANÇA; F.H. WEN; C.M.S MÁLAQUE; V. HADDAD JR (Eds). Animais peçonhentos no Brasil: biologia, clínica e terapêutica dos acidentes. São Paulo, Sarvier, FAPESP, 468p.
23. GUTIÉRREZ, J.M.; O. ARROYO & R. BOLAÑOS. 1980. Mionecrosis, hemorragia y edema inducidos por el veneno de Bothrops asper en raton blanco. Toxicon 18: 603-610.
24. GYGAX, P. 1971. Development, morphology and function of the venom gland (Duvernoy's gland) of Natrix tessellata. Acta Tropopica 28 (3): 226-274.
25. HILL, R.E. & S.P. MACKESSY. 2000. Characterization of venom (Duvernoy's secretion) from twelve species of colubrid snakes and partial sequence of four venom proteins. Toxicon 38: 1663-1687.
26. HUNSKAAR, S.; O.B. FASMER & K. HOLE. 1985. Formain test in mice, a useful technic for evaluation mild analgesics. Journal of Neuroscience Methods 14: 769-785.
27. JACKSON, K. 2003. The evolution of venom-delivery systems in snakes. Zoological Journal of the Linnean Society 137: 337-354.
28. JANSEN, D.W. 1987. The myonecrotic effect of Duvernoy's gland secretion of the Thamnophis elegans vagrans. Journal of Herpetology 21: 81-83.
29. KARDONG, K.V. 2002. Colubrid snakes and Duvernoy's "venom" glands. Journal of Toxicology-Toxin Reviews 21: 1-19.
30. KNIGHT, A. & D. MINDELL. 1994. On the phylogenetic relationship of Colubrinae, Elapidae, and Viperidae and the evolution of front-fanged venom systems in snakes. Copeia 1994 (1): 1-9.
31. KOCHVA, E. 1963. The development of the venom gland in the opisthoglyph snake Telescopus fallax with remarks on Thamnophis sirtalis (Colubridae, Reptilia). Copeia 1963 (2): 147-154.
32. KOCHVA, E. 1987. The origin of snake and evolution of the venom apparatus. Toxicon 25 (1): 65-106.
33. KONDO, H.; S. KONDO; I. IKESAWA; R. MURATA; A. OHSAKA. 1960. Studies of the quantitative method for determination of hemorrhagic activity of Habu snake venom. Japanese Journal of Medical Science and Biology 13: 43-51.
34. KORNALIK, F.; E. TÁBORKÁ & D. MEBS. 1978. Pharmacological and biological properties of a venom gland extract from the snake Thelotornis kirtlandi. Toxicon 16: 535-542.
35. LAWSON, R.; J.B. SLOWINSKI; B.I. CROTHER & F.T. BURBRINK. 2005. Phylogeny of Colubroidea (Serpentes): New evidence from mitochondrial and nuclear genes. Molecular Phylogenetics and Evolution 37: 581-601.
36. LEMOINE, K. & A. RODRÍGUEZ-ACOSTA. 2003. Haemorrhagic, proteolytic and neurotoxic activities procuced by Duvernoy's gland secretion from the false coral snake (Erythrolamprus bizona Jan, 1863) (Serpentes: Viperidae). Revista Científica FCV-LUZ 13 (5): 371-377.
37. LEMOINE, K.; M.E. GIRÓN; I. AGUILAR; L.F. NAVARRETE & A. RODRÍGUEZ-ACOSTA. 2004a. Proteolytic, Hemorrhagic, and Neurotoxic Activities Caused by Leptodeira annulata ashmeadii (Serpentes:Colubridae) Duvernoy's Gland Secretion. Wilderness & Environmental Medicine 15: 82-89.
38. LEMOINE, K.; L.M SALGUEIRO & A. RODRÍGUEZ-ACOSTA. 2004b. Neurotoxic, Hemorrhagic and Proteolytic Activities of Duvernoy's Gland Secretion from Venezuelan Ophistoglyphous Colubrid Snakes in Mice. Veterinary and Human Toxicology 46 (1): 10-14.
39. LITCHFIELD, J.T. & F. WILCOXON. 1949. A simplified method of evaluating dose-effect experiments. Jornal of Pharmacology and Experimental Therapeutics 96: 99-113.
40. LOWRY, O.H.; N.J. ROSEBROUGH; A.L. FARR and R.J. RANDALL. 1951. Protein measurement with the Folin phenol reagent. The Journal of Biological Chemistry 193: 265-275.
41. MACKESSY, S.P. 2002. Biochemistry and Pharmacology of Colubrid Snake Venoms. Journal Toxicology-Toxin Reviews 21: 43-83.
42. MANDELBAUM, F.R.; M.T. ASSAKURA; A.P. REICCHL & S.M.T. SERRANO. 1998. Philodryas venom metalloproteinases, p.1-2. In: A.J. BARRETT; N.D. RAWLINGS & J.F. WOESSNER (Eds). Handbook of proteolytic enzymes. New York, Academic Press, XXX+1666p.
43. MARKEWELL, M.; S.M. HASS; L.L. BIEBER & N.E. TOLBERT. 1978. A modification of the Lowry procedures to simplify protein determination in membrane and lipoprotein samples. Analytical biochemistry 87: 206-210.
44. NAVARRETE, L.F.; K. LEMOINE; A. RODRÍGUEZ- ACOSTA. 1999. Is the Opistoglyph Clelia clelia Duvernoy's Gland Secretion Haemorrhagic in Human? Acta Biologica Venezuelana 19 (3): 19-23.
45. NICKERSON, A.M. & R.W. HENDERSON 1976. A case of envenomation by the South American colubrid Philodryas olfersii. Herpetologica 32 (2): 197-198.
46. NISHIOKA, S.A. & P.V.P. SILVEIRA. 1994. Philodryas patagoniensis bite and local envenoming. Revista do Instituto de Medicina Tropical de São Paulo 36 (3): 279-281.
47. OHSAKA, A. 1979. Hemorrhagic, necrotizing and edema-forming effects of snakesvenoms, p. 481-546. In: C.Y. LEE (Ed.). Snake venoms, handbook of experimental pharmacology. Berlin, Springer, 1129p.
48. OVADIA, M. 1984. Embryonic development of Duvernoy's gland in the snake Natrix tessellata (Colubridae). Copeia 1984: 516-521.
49. PEICHOTO, M.E.; L.C. LEIVA; L.E. GUAIMÁ S MOYA; L. REY & O. ACOSTA. 2005. Duvernoy's gland secretion of Philodryas patagoniensis from the northeast of Argentina: effects on blood coagulation. Toxicon 45: 527-534.
50. PEICHOTO, M.E.; O. ACOSTA; L. LEIVA; P. TEIBLER; S. MARUÑAK & R. RUÍZ. 2004. Muscle and skin necrotizing and edema-forming activities of Duvernoy's gland secretion of the xenodontine colubrid snake Philodryas patagoniensis from the north-east of Argentina. Toxicon 44: 589-596.
51. PETERS, J.A. & OREJAS-MIRANDA, B. 1970. Catalogue of the Neotropical Squamata: Part I. Snakes. Bulletin of United States National Museum 297: 1-347.
52. PRADO-FRANCESCHI, J. & S. HYSLOPY. 2002. South American colubrid envenomations. Journal of Toxicology-Toxin Reviews 21: 117-158.
53. PRADO-FRANCESCHI, J.; S. HYSLOPY; J.C. COGO; A.L. ANDRADE; M.T. ASSAKURA; M.A. CRUZ-HÖFLING & L. RODRIGUES- SIMIONI. 1996. The effects of Duvernoy's gland secretion from the xenodontine colubrid Philodryas olfersii on striated muscle and the neuromuscular junction: partial characterization of a neuromuscular fraction. Toxicon 34 (4): 459-466.
54. PRADO-FRANCESCHI, J.; S. HYSLOPY; J.C. COGO; A.L. ANDRADE; M.T. ASSAKURA; A.P. REICHL; M.A. CRUZ-HÖFLING & L. RODRIGUES-SIMIONI. 1998. Characterization of a myotoxin from the Duvernoy's gland secretion of the xenodontinae colubrid Philodryas olfersii (green snake): effects on striated muscle and the neuromuscular junction. Toxicon 36 (10): 1407-1421.
55. PUORTO, G. & F.O.S. FRANÇA. 2003. Serpentes não peçonhentas e aspectos clínicos dos acidentes, p. 108-114. In: J.L.C. CARDOSO; F.O.S. FRANÇA; F.H. WEN; C.M.S. MÁLAQUE; V. HADDAD JR (Eds). Animais peçonhentos no Brasil: biologia, clínica e terapêutica dos acidentes. São Paulo, Sarvier, FAPESP, 468p.
56. RIBEIRO, L. A.; G. PUORTO & M.T. JORGE. 1994. Acidentes por serpentes do gênero Philodryas: avaliação de 132 casos. Revista da Sociedade Brasileira de Medicina Tropical 27 (Supl. 1): 87.
57. RIBEIRO, L.A.; G. PUORTO & M.T. JORGE. 1999. Bites by colubrid snake Philodryas olfersii: a clinical and epidemiological study of 43 cases. Toxicon 37 (1999): 943-948.
58. ROCHA, M.M.T.; S.R. TRAVAGLIA-CARDOSO & C. SATO. 2003. Reports of Human Snake Accidents Caused by Philodryas olfersii. Memórias do Instituto Butantan 60: 142.
59. ROCHA, M.M.T.; D. PAIXÃO-CAVALCANTE; D.V. TAMBOURGI & M.F.D. FURTADO. 2006. Duvernoy's gland secretion of Philodryas olfersii and Philodryas patagoniensis (Colubridae): Neutralization of local and systemic effects by commercial bothropic antivenom (Bothrops genus). Toxicon 47: 95-103.
60. ROSENBERG, H.I.; A. BDOLAH & E. KOCHVA. 1985. Lethal factors and enzymes in the secretion from Duvernoy's gland of three colubrid snakes. The Journal of Experimental Zoology 233: 5-14.
61. ROSENFELD, G. 1971. Symptomatology, pathology, and treatment of snake bites in South America, p. 345-384. In: W. BUCHERL; E.E. BUCKLEY & V. DEULOFEU (Eds). Venomous animals and their venoms. New York, Academic Press, vol. 2, 687p.
62. SALOMÃO, M.G.; A.B.P. ALBOLEA & S.M. ALMEIDA-SANTOS. 2003. Colubrid snakebite: a public health problem in Brazil. Herpetological Review 34 (4): 307-312.
63. a Delegacia Regional de Saúde. Arquivos da Sociedade de Zoológicos do Brasil (14-16): 21.
64. SANCHEZ, E.F.; T.V. FREITAS; D.L. FERREIRA-ALVES; D.T. VELARDE; M.R. DINIZ; M.N. CORDEIRO; G. AGOSTINI-COTTA & C.R. DINIZ. 1992. Biological activities of venoms from south american snakes. Toxicon, Oxford, 30(1): 95-103.
65. SANTOS-COSTA, M.C.; A.B. OUTEIRAL; F. D'AGOSTINI & L. CAPPELIARI. 2001. Freqüência de acidentes ofídicos na região da grande Porto Alegre e cidades próximas, RGS, Brasil. Comunicação do Museu de Ciências e Tecnologia da PUCRS, Série Zoologia, 14 (1): 89-93.
66. SILVA, M. V. & M. A. BUONONATO. 1983. Relato clínico de envenenamento humano por Philodryas olfersii. Memórias do Instituto Butantan 47/48: 121-126. [1984]
67. SILVEIRA, P.V.P. & S.A. NISHIOKA. 1992. Non-venomous snake bite and snake bite without envenoming in a brazilian teaching Hospital. Analysis of 91 cases. Revista do Instituto de Medicina Tropical de São Paulo 34: 499-503.
68. TANJONI, I.; D. BUTERA; P.J. SPENCER; A.H. TAKEHARA; I. FERNANDES & A.M. MOURA-DA- SILVA. 2003. Phylogenetic conservation of a snake venom metalloproteinase epitope recognized by monoclonal antibody that neutralizes hemorrhagic activity. Toxicon 42: 809-816.
69. THEAKSTON, R.D.G. & H.A. REID. 1983. Development of simple standard assay procedures for the characterization of snake venoms. Bulletin of the World Health Organization 61: 949-956.
70. VANZOLINI, P. 1986. Levantamento herpetológico da área do estado de Rondônia sob influência da rodovia BR 364. Brasília, CNPq, Relatório de pesquisa, 50p.
71. VEST, D.K. 1988. Some effects and properties of Duvernoy's gland secretion from Hypsiglena torquata texana (Texas night snake). Toxicon 26 (4): 417-419.
72. VEST, D.K.; S.P. MACKESSY & K.V. KARDONG. 1991. The unique Duvernoy's secretion of the brown tree snake (Boiga irregularis). Toxicon 29 (4/5): 532-535.
73. VILLARROEL, M.S.; F. ZELANTE; R. ROLIM ROSA & R.S. FURLANETTO. 1978. Padronização da titulação da atividade tóxica de venenos botrópicos, em camundongos. Memórias do Instituto Butantan 42/43: 311-323. [1979]
74. th ed., 425p.
75. WEINSTEIN, S.A.; D. CHISZAR; R.C. BELL & L.A. SAMITH. 1991. Lethal potency and fractionation of Duvernoy's secretion from the brown tree snake, Boiga irregularis. Toxicon 29 (4/5): 401-407.
76. WEINSTEIN, S.A. & K.V. KARDONG. 1994. Properties of Duvernoy's secretions from opisthogliphous and aglyphous colubrid snakes. Toxicon 32 (10): 1161-1185.
77. YAMAKAWA, S.A.; M. NOZAKI & Z. HOKAWA. 1976. Fractionation of sakishimahabu (Trimeresurus elegans) venom and lethal, hemorrhagic and edema-formin activities of the fractins, p. 97-109. In: A. OHSAKA; K. HAYASHI; Q.Y. SAWAY (Eds). Animal, plant and microbial toxins. New York, Plenum, vol. 1, XXV+555p.