Neurotoxic, Hemorrhagic and Proteolytic Activities of Duvernoy's Gland Secretion from Venezuelan Opisthoglyphous Colubrid Snakes in Mice

Veterinary and Human Toxicology

Volumn 46, Issue 1, 2004, Pages 10-14

  Lemoine, K ^a   Salgueiro, L M ^a   Rodriguez Acosta A ^a   Acosta, J A ^b  

^a UNIVERSIDAD CENTRAL DE VENEZUELA   (Venezuela)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GELATINASE; SNAKE VENOM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLEEDING; CHICK EMBRYO; CONTROLLED STUDY; DUVERNOY GLAND; DUVERNOY GLAND SECRETION; EMBRYO; ENZYME ACTIVITY; MALE; MOUSE; MOUSE STRAIN; NEUROTOXICITY; NONHUMAN; PERITONEUM; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN DEGRADATION; PROTEIN PURIFICATION; SALIVARY GLAND; SALIVATION; SKIN; SNAKE; SPECIES DIFFERENCE; THAMNODYNASTES STIGILIS;

ANIMALS; CHICK EMBRYO; COLUBRIDAE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GELATINASES; HEMORRHAGE; LETHAL DOSE 50; MALE; MICE; PERITONEUM; SKIN; SNAKE VENOMS;

ANIMALIA; COLUBRIDAE; GALLUS GALLUS; SERPENTES; THAMNODYNASTES;

EID: 0345742546     PISSN: 01456296     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Kraus F, Brown WM: Phylogenetic relationships of colubroids snakes based on mitochondrial DNA sequences. Zool J Linneus Soc 62: 421-442, 1998.
2. Heise PJ, Maxson LR, Dowling HG et al: Higher-level snake phylogeny inferred from mitochondrial DNA sequences of 12s rRNA and 16s rRNA genes. Mol Biol Evol 12: 259-265, 1995.
3. Lancini AR: Serpientes de Venezuela. Ediciones E. Armitano, Caracas, Venezuela: 1-262, 1979.
4. Perez-Santos C, Moreno AG: Una nueva especie de Thamnodynastes (Serpentes:Colubridae) en el norte de Colombia. Boll Mus Reg Sci Nat Torino 7: 1-9, 1989.
5. Meyers CW, Donnelly MA: A new herpetofauna from Cerro Yavi, Venezuela: first results of the Robert G. Goelet American Museum-Terramar expedition to the Northwestern Tepuis. Am Mus Novitates 3172: 1-56, 1996.
6. Machado A, Rodriguez-Acosta A: Animales Venenosos y Ponzoñosos de Venezuela. Consejo de Desarrollo Científico y Humanistico de la Universidad Central de Venezuela, Caracas, Venezuela: 1-106, 1997.
7. Poey F: Mordedura de un Jubo. El Genio Científico de la Habana, 1: 94-98, 1873.
8. Jaume ML: Notas sobre mordeduras tóxicas de serpientes (Reptilia-Serpientes-Colubridae). Rev Cub Med Trop 35: 224-230, 1983.
9. Assakura M, Reichl P, Mandelbaum FR: Isolation and characterization of five fibrin(ogen)olytic enzymes from the venom of Philodryas olfersii (Green snake). Toxicon 32: 819-831, 1994.
10. Weinstein SA, Kardong KV: Properties of Duvernoy's secretions from opisthoglyphous and aglyphous colubrid snakes. Toxicon 32: 1161-1185, 1994.
11. Hill RE, McKessy P: Characterization of venom (Duvernoy's secretion) from twelve species of colubrid snakes and partial sequence of four venom proteins. Toxicon 38: 1663-1687, 2000.
12. Anonymous: Principles of Laboratory Animal Care. Guide For the Care and Use of Laboratory Animals. National Institute of Health, Maryland: 1-86, 1985.
13. Laemmli UK: Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature, 227: 680-685, 1970
14. Dunn BE, Boone MA: Growth of the chick embryo in vitro. Poultry Science 55: 1067-1071, 1976.
15. Sells PG, Richards AM, Laing GD et al: The use of hens' eggs Sells, an alternative to the conventional in vivo rodent assay for antidotes to hemorrhagic venoms. Toxicon 35: 1413-1421, 1997.
16. Navarrete L, Lemoine K, Rodriguez-Acosta A: Is the opisthoglyphous Clelia clelia Duvernoy's gland secretion haemorrhagic in humans? Act Biol Ven 19: 19-23, 1999.
17. Kondo H, Kondo S, Ikezawa H et al: Studies on the quantitative method for determination of hemorrhagic activity of habu snake venom. Jap J Med Sci Biol, 13: 43-49, 1960.
18. Gutierrez JM, Leon G, Rojas G et al: Neutralization of local tissue damage induced by Bothrops asper (terciopelo) snake venom. Toxicon, 36: 1529-38, 1998.
19. Huang SY, Perez JC: Comparative study on hemorrhagic and proteolytic activities of snake venoms. Toxicon 18: 421-426, 1980.
20. Huang SY, Perez JC: A comparative electron microscopic study of myonecrosis induced by Crotalus atrox (Western Diamondback Rattlesnake) in grey wood rats and mice. Toxicon 20: 443-449, 1982.
21. Cowles RB, Bogert CM: Observations on the California lyre snake, Trimorphodon vandenburghi, Klauber, with notes on the effectiveness of its venom. Copeia 1935: 80, 1935.
22. De Lema T: Relato de um envenenamento por uma cobra nao venenosa. Natur Rev 4: 62-63, 1978.
23. Cook DG: A case of envenomation by the neotropical colubrid snake, Stenorrhina freminvillei. Toxicon 22: 823-827, 1984.
24. De Lisle HF: Boiga cyanea (Green Cat-eye Snake): Envenomation. Herpetol Rev 15: 112, 1984.
25. De Araujo E, Dos Santos AC: Cases of human envenoming caused by Philodryas olfersii and Philodryas patagoniensis (Serpentes: Colubridae). Rev Soc Bras Med Trop 30: 517-519, 1997.
26. De Lisle HF: Venomous colubrid snakes. Bul Chicago Herpetol Soc 17: 1-17, 1982.
27. Rodriguez-Acosta A, Girón ME, Aguilar I et al: A case of envenomation by a "non venomous" snake (Philodryas viridissimus) and comparison between this snake Duvernoy's gland secretion and northern South America rattlesnakes venoms. Arch Ven Med Trop 1: 29-32, 1997.
28. Fox JW, Long C: The ADAMs/MDC family of proteins and their relationships to the snake venom metalloproteinases. In Bailey GS: Enzymes from Snake Venom. Alaken Press, Fort Collins, CO: 151-178, 1998.
29. Munekiyo SM, MacKessy SP: Effects of temperature and storage conditions on the electrophoretic, toxic and enzymatic stability of venom components. Comp Biochem Physiol 119B: 119-127, 1998.
30. Gutierrez JM, Ruvacado A: Snake venom metalloproteinases: their role in the pathogenesis of local tissue damage. Biochimie 82: 841-850, 2000.
31. Mebs D: Analysis of Leptodeira annulata venom. Herpetologica 24: 338, 1968.
32. Grenard S: Medical Herpetology. Reptile and Amphibian Magazine, Pottsville, PA: 1-139, 1994.
33. Fontana MD, Heleno MG, Vital Brazil O: Mode of action of Duvernoy's gland extracts from the colubrid Dryadophis bifossatus in the chick biventercervicis nerve-muscle preparation Toxicon 34: 1187-1190, 1996.
34. 2 from the venom of Taiwan habu (Trimeresurus mucrosquamatus). Biochem 311: 895-900, 1995.