Arsenic accumulation decreased in metallothionein null cisplatin-resistant cell lines

Journal of Toxicological Sciences

Volumn 32, Issue 3, 2007, Pages 321-328

  Suzuki, Toshihiro ^a   Ohata, Shigeki ^a   Togawa, Tadayasu ^a   Himeno, Seiichiro ^b   Tanabe, Shinzo ^a  

^a MEIJI PHARMACEUTICAL UNIVERSITY   (Japan)

^b TOKUSHIMA BUNRI UNIVERSITY   (Japan)

Author keywords

Arsenate; Arsenite; Cisplatin; Metallothionein; Multidrug resistant protein; Resistance

Indexed keywords

ANTIMONY; ARSENIC; ARSENIC ACID; ARSENIC TRIOXIDE; CADMIUM; CISPLATIN; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; METAL DERIVATIVE; METALLOTHIONEIN; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN 2; MULTIDRUG RESISTANCE PROTEIN 3; MULTIDRUG RESISTANCE PROTEIN 4; MULTIDRUG RESISTANCE PROTEIN 5;

ANIMAL CELL; ARTICLE; BIOACCUMULATION; CANCER RESISTANCE; CELL TRANSPORT; CELL VIABILITY; CONTROLLED STUDY; CROSS RESISTANCE; DRUG ACCUMULATION; GENE EXPRESSION; MOUSE; NONHUMAN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 34548622716     PISSN: 03881350     EISSN: 18803989     Source Type: Journal    
DOI: 10.2131/jts.32.321     Document Type: Article

References (25)

1. Chin, J.L., Banerjee, D., Kadhim, S.A., Kontozoglou, T.E., Chauvin, P.J. and Cherian, M.G. (1993): Metallothionein in testicular germ cell tumors and drug resistance. Clinical correlation Cancer, 72, 3029-3035.
2. Cheng, T.C., Manorek, G., Samimi, G., Lin, X., Berry, C.C. and Howell, S.B. (2006): Identification of genes whose expression is associated with cisplatin resistance in human ovarian carcinoma cells. Cancer Chemother Pharmacol., 58, 384-395.
3. Chen, Z.S., Mutoh, M., Sumizawa, T., Furukawa, T., Haraguchi, M., Tani, A., Saijo, N., Kondo, T. and Akiyama, S. (1998): An active efflux system for heavy metals in cisplatin-resistant human KB carcinoma cells. Exp Cell Res., 240, 312-320.
4. Chuman, Y., Chen, Z.S., Sumizawa, T., Furukawa, T., Haraguchi, M., Takebayashi, Y., Niwa, K., Yamada, K., Aikou, T. and Akiyama, S. (1996): Characterization of the ATP-dependent LTC4 transporter in cisplatin-resistant human KB cells. Biochem. Biophys. Res. Commun., 226, 158-165.
5. Fujishiro, H., Okugaki, S., Nagao, S., Satoh, M. and Himeno, S. (2006): Characterization of Gene Expression Profiles of Methallothionein-Null Cadmium-Resistant Cells. J. Health Sci., 52, 292-299.
6. Ghosh, M., Shen, J. and Rosen, B.P. (1999): Pathways of As (III) detoxification in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. U S A, 96, 5001-5006.
7. Hishikawa, Y., Abe, S., Kinugasa, S., Yoshimura, H., Monden, N., Igarashi, M., Tachibana, M. and Nagasue, N. (1997): Overexpression of metallothionein correlates with chemoresistance to cisplatin and prognosis in esophageal cancer. Oncology, 54, 342-347.
8. Ishikawa, T., Wright, C.D. and Ishizuka, H. (1994): GS-X pump is functionally overexpressed in cisdiamminedichloroplatinum (II)-resistant human leukemia HL-60 cells and down-regulated by cell differentiation. J. Biol. Chem., 269, 29085-29093.
9. Kondo, Y., Woo, E.S., Michalska, A.E., Choo, K.H. and Lazo, J. S. (1995) : Metallothionein null cells have increased sensitivity to anticancer drugs. Cancer Res., 55, 2021-2023.
10. Kotoh, S., Naito, S., Sakamoto, N., Goto, K. and Kumazawa, J. (1994): Metallothionein expression is correlated with cisplatin resistance in transitional cell carcinoma of the urinary tract. J. Urol., 152, 1267-1270.
11. Kumagai, Y. and Sumi, D. (2007): Arsenic, Signal Transduct ion, Transcription Factor, and Biotransformation Involved in Cellular Response and Toxicity. Annu. Rev. Pharmacol. Toxicol., 47, 243-262.
12. Nishio, K., Nakamura, T., Koh, Y., Suzuki, T., Fukumoto, H. and Saijo, N. (1999): Drug resistance in lung cancer. Curr Opin Oncol., 11, 109-115.
13. Rosenberg, B. (1985): Fundamental studies with cisplatin. Cancer, 55, 2303-23l6.
14. Roberts, J.J. and Pascoe, J.M. (1972): Cross-linking of complementary strands of DNA in mammalian cells by antitumour platinum compounds. Nature, 235, 282-284.
15. Satoh, M., Aoki, Y. and Tohyama, C. (1997): Protective role of metallothionein in renal toxicity of cisplatinum., Cancer Chemother. Pharmacol., 40, 358-362.
16. Shen, D.W., Liang, X.J., Suzuki, T. and Gottesman, M.M. (2006): Identification by functional cloning from a retroviral cDNA library of cDNAs for ribosomal protein L36 and the 10-kDa heat shock protein that confer cisplatin resistance, Mol. Pharmacol., 69, 1383-1388.
17. Suzuki, T., Nishio, K. and Tanabe, S. (2001): The MRP family and anticancer drug metabolism. Curr. Drug Metab., 2, 367-377.
18. Suzuki, T., Agui, M., Togawa, T., Naganuma, A., Nishio, K. and Tanabe, S. (2003): MRP5b/SMRP mRNA is Highly Expressed in Metallothionein-Deficient Mouse Liver., J. Health Sci., 49, 524-526.
19. Suzuki, T., Ishibashi, K., Ohata, S., Sato, N., Yumoto, A., Togawa, T., Nishio, K., Hirunuma, R., Haba, H., Enomoto, S. and Tanabe, S. (2006): Efflux study of trace elements in a cisplatin-resistant lung cancer cell line using a multitracer technique. RIKEN Accel. Prog. Rep., 39, 124.
20. Takahashi, M., Suzuki, T., Yumoto, A., Togawa, T., Haba, H., Enomoto, S., Nishio, K. and Tanabe, S. (2006): Analysis of Cisplatin Behavior in a Non-Small Cell Lung Cancer (NSCLC) Cell Line., Biomed. Res. Trace Elements, 17, 332-334.
21. Taniguchi, K., Wada, M., Kohno, K., Nakamura, T., Kawabe, T., Kawakami, M., Kagotani, K., Okumura, K., Akiyama, S. and Kuwano, M. (1996): A human canalicular multispecific organic anion transporter (cMOAT) gene is overexpressed in cisplatin-resistant human cancer cell lines with decreased drug accumulation. Cancer Res., 56, 4124-4129.
22. Uchiumi, T., Hinoshita, E., Haga, S., Nakamura, T., Tanaka, T., Toh, S., Furukawa, M., Kawabe, T., Wada, M., Kagotani, K., Okumura, K., Kohno, K., Akiyama, S. and Kuwano, M. (1998): Isolation of a novel human canalicular multispecific organic anion transporter, cMOAT2/MRP3, and its expression in cisplatin-resistant cancer cells with decreased ATP-dependent drug transport., Biochem Biophys Res Commun., 252, 103-110.
23. Yanagiya, T., Imura, N., Enomoto, S., Kondo, Y. and Himeno, S. (2000): Suppression of a high-affinity transport system for manganese in cadmium-resistant metallothionein-null cells., J. Pharmacol. Exp. Ther., 292, 1080-1086.
24. Yamabe, Y., Kondo, Y., Endo, W., Sasaya, K., Imura, N., Hasegawa, T., Seko, Y. and Himeno, S. (2001): Characterization of cis-Diamminedichloroplatinum (II)-Resistant Murine Cell Lines Derived from Metallothionein Null Cells. J. Health Sci., 47, 378-384.
25. Yasui, K., Mihara, S., Zhao, C., Okamoto, H., Saito-Ohara, F., Tomida, A., Funato, T., Yokomizo, A., Naito, S., Imoto, I., Tsuruo, T. and Inazawa, J. (2004): Alteration in copy numbers of genes as a mechanism for acquired drug resistance., Cancer Res., 64, 1403-1410.