Protective role of metallothionein in renal toxicity of cisplatinum

Cancer Chemotherapy and Pharmacology

Volumn 40, Issue 4, 1997, Pages 358-362

  Satoh, Masahiko ^a   Aoki, Yasunobu ^a   Tohyama, Chiharu ^a  

^a NATIONAL INSTITUTE FOR ENVIRONMENTAL STUDIES   (Japan)

Author keywords

Bismuth; Cisplatinum; Metallothionein; Renal toxicity; Zinc

Indexed keywords

BISMUTH NITRATE; CISPLATIN; METAL DERIVATIVE; METALLOTHIONEIN; ZINC SULFATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; HISTOCHEMISTRY; INTRAPERITONEAL DRUG ADMINISTRATION; LETHALITY; MOUSE; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTECTION; PROTEIN INDUCTION; STRAIN DIFFERENCE; SUBCUTANEOUS DRUG ADMINISTRATION; TRANSGENIC MOUSE;

ANIMALS; ANTINEOPLASTIC AGENTS; BISMUTH; BLOOD UREA NITROGEN; CISPLATIN; CREATININE; FEMALE; INJECTIONS, INTRAPERITONEAL; KIDNEY; KIDNEY DISEASES; METALLOTHIONEIN; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; NITRATES; SULFHYDRYL COMPOUNDS; ZINC SULFATE;

EID: 0030945681     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002800050670     Document Type: Article

References (30)

1. Anderson ME, Naganuma A, Meister A (1990) Protection against cisplatin toxicity by administration of glutathione ester. FASEB J 4: 3251
2. Basu A, Laxo JS (1990) A hypothesis regarding the protective role of metullothioneins against the toxicity of DNA interactive anticancer drugs. Toxicol Lett 50: 123
3. 3+ -pretreatment in the rat in vivo and in vitro. Biochem Pharmacol 41: 369
4. Costa LG, Murphy SD (1986) Effect of diethylmaleate and other glututhione depletors on protein synthesis. Bioehem Pharmacol 35: 3383
5. Ellman GL (1959) Tissue sulfhydryl groups. Arch Biochem Biophys 82: 70
6. Gemba M, Fukuishi N, Nakano S (1988) Effect of N.Ń-diphenyl-p-phenylenediamine pretreatment on urinary enzyme excretion in cisplatin nephrotoxicity in rats. Jpn J Pharmacol 46: 90
7. Hanneman J, Baumann K (1988) Cisplatin-induced lipid peroxidation and decrease of gluconeogenesis in rat kidney cortex: different effects of antioxidants and radical scavengers. Toxicology 51: 119
8. Kagi JHR, Schaffer A (1988) Biochemistry of metallothionein. Biochemistry 27: 8509
9. Kasahara K, Fujiwaru Y, Nishino K, Ohmori T, Sugimoto Y, Komiya K, Matstida T, Saijo N (1991) Metallothionein content correlates with the sensitivity of human small cell lung cancer cell lines to cisplatin. Cancer Res 51: 3237
10. Kondo Y, Satoh M, Imura N, Akimoto M (1991) Effect of bismuth nitrate given in combination with cis-diamminedichloroplatinum(II) on the antitumor activity and renal toxicity of the latter in nude mice inoculated with human bladder tumor. Cancer Chemother Pharmacol 29: 19
11. Kondo Y, Woo ES, Michalska AE, Choo KHA, Lazo JS (1995) Metallothionein null cells have increased sensitivity to anticancer drugs. Cancer Res 55: 2021
12. Lazo JS, Kondo Y, Dellapiazza D, Michalska AE, Choo KHA, Pitt BR (1995) Enhanced sensitivity to oxidative stress in cultured embryonic cells from transgenic mice deficient in metallothionein I and II genes. J Biol Chem 270: 5506
13. Madias NE, Harrington JT (1978) Platinum nephrotoxicity. Am J Med 65: 307
14. Masters BA, Kelly EJ, Quaife CJ, Brinster RL, Pulmiter RD (1994) Targeted disruption of metallothionein I and II genes increases sensitivity to cadmium. Proc Natl Acad Sci USA 91: 584
15. Mayer RD, Lee K, Cockett ATK (1987) Inhibition of cisplatin-induced nephrotoxieity in rats by buthionine sulfoximine, a glutathione synthesis inhibitor. Cancer Chemother Pharmacol 20: 207
16. Merrin CE (1979) Treatment of genitourinary tumors with cis-dichlorodiainmineplatinum(II): experience in 250 patients. Cancer Treat Rep 63: 1579
17. Michalska AE, Choo KHA (1993) Targeting and germ-line transmission of a null mutation at the metallothionein I and II loci in mouse. Proc Null Acad Sci USA 90: 8088
18. Naganuma A, Satoh M, Imura N (1985) Protective effect of metallothionein inducing metals on lethal toxicity of cis-diamminedichloroplatinum in mice. Toxicol Lett 24: 203
19. Naganuma A, Satoh M, Imura N (1987) Prevention of lethal and renal toxicity of cis-diamminedichloroplatinuin(II) by induction of metallothionein synthesis without compromising its antitumor activity in mice. Cancer Res 47: 983
20. Nishimura H, Nishimura N, Kobayashi S, Tohyama C (1991) Immunohistochemical localization of metallothionein in the eye of rats. Histochemistry 95: 535
21. Rosenberg RC, Van Camp L, Trosko JE, Mansour VH (1969) Platinum compounds: a new class of potent antitumor agents. Nature 222: 385
22. Sato M, Bremner I (1993) Oxygen free radicals and metallothionein. Free Radic Biol Med 14: 325
23. Satoh M, Naganuma A, Imura N (1988) Metallothionein induction prevents toxic side effects of cisplatin and adriamycin used in combination. Cancer Chem Pharmacol 21: 176
24. Satoh M, Kloth DM, Kadhim SA, Chin JL, Naganuma A, Imura N, Cherian MG (1993) Modulation of both cisplatin nephrotoxicity and drug resistance in murine bladder tumor by controlling metallolhionein synthesis. Cancer Res 53: 1829
25. Satoh M, Tsuchiya T, Kumada Y, Naganuma A, Imura N (1993) Protection against lethal toxicity of various anticancer drugs by preinduction of metallothionein synthesis in mice. J Trace Elem Exp Med 6: 41
26. Sharma RP, Edwards IR (1983) cis-Platinum: subcellular distribution and binding to cytosolic ligands. Biochem Pharmacol 32: 2665
27. Sommer S, Thorling EB, Jakobsen A, Steiness E, Ostergaard K (1989) Can bismuth decrease the kidney toxic effect of cisplatinum. Eur J Cancer Clin Oncol 23: 1903
28. Takahashi A, Takagi M, Hishida H, Sakamoto Y, Takagi N, Amano H, Ogura Y (1989) The pharmakokinetics of cisplatin and its influence on renal function according to different infusion methods (Report II) alleviation of renal impairment by bismuth subnitrate combined with ginseng and tang-keui ten-. Jpn J Cancer Chemother 16: 2405
29. Zelazowski AJ, Garvey JS, Hoeschele JD (1984) In vivo and in vitro binding of platinum to metallothionein. Arch Biochem Biophys 229: 246
30. Zunino F, Tofanetti O, Besati A, Cavalletti E, Savi G (1983) Protective effect of reduced glutathione against cis-dichlorodiammine platinum (II)-induced nephrotoxicity and lethal loxicity. Tumori 69: 105