Alteration in Copy Numbers of Genes as a Mechanism for Acquired Drug Resistance

Cancer Research

Volumn 64, Issue 4, 2004, Pages 1403-1410

  Yasui, Kohichiroh ^a,b   Mihara, Saori ^a   Zhao, Chen ^a   Okamoto, Hiroyuki ^a   Saito Ohara, Fumiko ^a,b   Tomida, Akihiro ^c   Funato, Tadao ^d   Yokomizo, Akira ^e   Naito, Seiji ^e   Imoto, Issei ^a,b   Tsuruo, Takashi ^c   Inazawa, Johji ^a,b  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^e KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; ANTISENSE OLIGONUCLEOTIDE; CAMPTOTHECIN; CISPLATIN; CYTARABINE; DEOXYCYTIDINE KINASE; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); DOXORUBICIN; ETOPOSIDE; MULTIDRUG RESISTANCE PROTEIN 1; PROTEIN BCL 2;

ABCA3 GENE; ABCB1 GENE; ABCB10 GENE; ABCB11 GENE; ABCB6 GENE; ABCB8 GENE; ABCC1 GENE; ABCC4 GENE; ABCC9 GENE; ABCD3 GENE; ABCD4 GENE; ABCE1 GENE; ABCF2 GENE; ARTICLE; BCL2L10 GENE; BCL2L2 GENE; CANCER CELL CULTURE; CANCER THERAPY; CHROMOSOME ANALYSIS; COMPARATIVE GENOMIC HYBRIDIZATION; CONTROLLED STUDY; DNA CONTENT; DNA COPY NUMBER; DOWN REGULATION; DRUG RESISTANCE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE; GENE OVEREXPRESSION; GENOME; HUMAN; HUMAN CELL; MCL1 GENE; MULTIDRUG RESISTANCE; PRIORITY JOURNAL; SUPPRESSION SUBTRACTIVE HYBRIDIZATION;

APOPTOSIS; ATP-BINDING CASSETTE TRANSPORTERS; CAMPTOTHECIN; CELL LINE, TUMOR; CYTARABINE; DRUG RESISTANCE, NEOPLASM; ETOPOSIDE; GENE AMPLIFICATION; GENE DOSAGE; GENES, BCL-2; HUMANS;

EID: 10744224230     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-3263-2     Document Type: Article

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