Inhibitory effect of Hemidesmus indicus and its active principle 2-hydroxy 4-methoxy benzoic acid on ethanol-induced liver injury

Fundamental and Clinical Pharmacology

Volumn 21, Issue 5, 2007, Pages 507-514

  Saravanan, Nadana ^a   Nalini, Namasivayam ^a  

^a ANNAMALAI UNIVERSITY   (India)

Author keywords

2 hydroxy 4 methoxy benzoic acid; Collagen; Ethanol; Hemidesmus indicus; Liver; Matrix metalloproteinases

Indexed keywords

2 HYDROXY 4 METHOXYBENZOIC ACID; ALCOHOL; ASCORBIC ACID; COLLAGEN; GELATIN; GELATINASE A; GELATINASE B; HEMIDESMUS INDICUS EXTRACT; HYDROXYPROLINE; UNCLASSIFIED DRUG;

ALCOHOL LIVER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CROSS LINKING; DRUG EFFECT; ENZYME ACTIVITY; EXTRACELLULAR MATRIX; FLUORESCENCE; GENE EXPRESSION; HEMIDESMUS INDICUS; LIPID PEROXIDATION; LIVER FIBROSIS; LIVER INJURY; MALE; NONHUMAN; PLANT ROOT; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; RAT; STATISTICAL SIGNIFICANCE; WISTAR RAT; ZYMOGRAPHY;

ANIMALS; ASCORBIC ACID; BENZOATES; CENTRAL NERVOUS SYSTEM DEPRESSANTS; COLLAGEN; DISEASE MODELS, ANIMAL; ETHANOL; FLUORESCENCE; HEMIDESMUS; HYDROXYPROLINE; LIPID PEROXIDATION; LIVER; LIVER DISEASES, ALCOHOLIC; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; PLANT ROOTS; RATS; RATS, WISTAR;

EID: 34548602526     PISSN: 07673981     EISSN: 14728206     Source Type: Journal    
DOI: 10.1111/j.1472-8206.2007.00500.x     Document Type: Article

References (43)

1. Friedman S.L. Molecular mechanisms of hepatic fibrosis and principles of therapy. J. Gastroenterol. (1997) 32 424 430.
2. Prockop D.J., Kivirikko K.I. Collagens. Molecular biology, diseases and potentials for therapy. Annu. Rev. Biochem. (1995) 64 403 434.
3. George A., Malone J.P., Veis A. The secondary structure of type I collagen N- telopeptide as demonstrated by Fourier transform IR spectroscopy and molecular modeling. Proc. Indian Acad. Sci. (Chem. Sci.) (1999) 111 121 131.
4. Nimni M.E., Han B.O. Collagen and collagen-glycosaminoglycan matrices as carriers for growth factors. Proc. Indian Acad. Sci. (Chem. Sci.) (1999) 111 283 289.
5. Brown J.C., Timpl R. The collagen superfamily. Int. Arch. Allergy Immunol. (1995) 107 484 490.
6. Warier P.K. Eugenia jambolana Linn, in : Warier P.K., Nambiar V.P.K., Ramankutty C. (Eds Indian medicinal plants, Orient Longman, Madras, India, 1995.
7. Nadkarni A.N. Indian Materia Medica, Vol. 1, Popular Book Depot, Bombay, India, 1989, p. 619.
8. Jain S.P., Singh S.C. Ethno-Medico-Botanical Survey of Ambikapur District, MP. Fourth International Congress of Ethnobiology, NBRI, Lucknow, UP, India, 1994.
9. Alam M.I., Auddy B., Gomes A. Isolation, purification and partial characterization of viper venom inhibiting factor from the root extract of the Indian medicinal plant sarsaparilla (Hemidesmus indicus R.Br). Toxicon (1994) 32 1551 1557.
10. Baheti J.R., Goyal R.K., Shah G.B. Hepatoprotective activity of Hemidesmus indicus R. br. in rats. Indian J. Exp. Biol. (2006) 44 399 402.
11. Anonymous. Indian Pharmacopoeia, 2nd edn, Government of India, New Delhi, 1966, p. 57.
12. Anoop A., Jegadeesan M., Santhi G. Pharmacognostical studies on roots of varieties of Hemidesmus indicus R.Br. J. Swamy Bot. Club (2002) 19 37 43.
13. Das S., Prakash R., Devaraj S.N. Antidiarrhoeal effects of methanolic root extract of Hemidesmus indicus (Indian sarsaparilla) - an in vitro and in vivo study. Indian J. Exp. Biol. (2003) 41 363 366.
14. Chandrakasan G., Torchia D.A., Piez K.A. Preparation of intact monomeric collagen from tail tendon and skin and the structure of the nonhelical ends in solution. J. Biol. Chem. (1976) 251 6062 6067.
15. Woessner J.F. The determination of hydroxyproline in tissue and protein samples containing small portions of this imino acid. Arch. Biochem. Biophys. (1961) 93 440 447.
16. Monnier V.M., Vishwanath V., Frank K.E., Elmets C.A., Dauchot P., Kohn R.R. Relation between complications of type I diabetes mellitus and collagen-linked fluorescence. N. Engl. J. Med. (1986) 314 403 408.
17. Miller E.J., Rhodes R.K. Preparation and characterization of different types of collagen. Methods Enzymol. (1982) 82 33 64.
18. Nutting G.C., Borasky R. Microscopic methods for determining shrinkage temperature of collagen and leather. J. Am. Leather Chem. Assoc. (1949) 44 831 839.
19. Vangsness C.T., Mitchell W., Nimni M., Erlich M., Saadat V., Schmotzer H. Collagen shortening. An experimental approach with heat. Clin. Orthop. (1997) 337 267 271.
20. Ohkawa H., Ohishi N., Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal. Biochem. (1979) 95 351 358.
21. Yagi K. Lipid peroxides and human disease. Chem. Physiol. Lipids (1978) 45 337 351.
22. Omye S.T., Turnbull J.D., Sauberlich H.E. Selected methods for the determination of ascorbic acid in animal cells, tissues, and fluids. Methods Enzymol. (1979) 62 3 11.
23. Neely A.N., Brown R.L., Clendening C.E., Orkiff M.M., Gardner J., Greenhalgh D.G. Proteolytic activity in human burn wounds. Wound Repair Regen. (1997) 5 302 309.
24. Carter E.A., McCarron M.J., Alpert E., Isselbacher K.J. Lysyl oxidase and collagenase in experimental acute and chronic liver injury. Gastroenterology (1982) 82 526 534.
25. Senthilkumar R., Sengottuvelan M., Nalini N. Protective effect of glycine supplementation on the levels of lipid peroxidation and antioxidant enzymes in the erythrocyte of rats with alcohol-induced liver injury. Cell Biochem. Funct. (2003) 21 1 6.
26. Parthasarathy S., Wieland E., Steinberg A. A role for endothelial cell lipooxygenase in the oxidative modifications of low-density lipoprotein. Proc. Natl Acad. Sci. USA (1989) 86 1046 1050.
27. 4 injured rats. Clin. Sci. (2002) 97 315 320.
28. Senthilkumar R., Viswanathan P., Nalini N. Effect of glycine on oxidative stress in rats with alcohol-induced liver injury. Pharmazie (2004) 59 55 60.
29. Rao C.N., Rao V.H., Sanjeevi R. Effect of bioflavonoids on the mechanical and thermal properties of skin and tendon. Indian J. Biochem. Biophys. (1981) 18 224 228.
30. Kagan H.M. Intra and extracellular enzymes of collagen biosynthesis as biological and chemical targets in the control of fibrosis. Acta Trop. (2000) 77 147 152.
31. Mang J., Sakata N., Takebayashi S. AGEs of the Mail-lard reaction in aortic pepsin- insoluble and pepsin soluble collagen from diabetic rats. Diabetes (1996) 45 1037 1043.
32. Sakata N., Meng J., Jimi S., Takebayashi S. Nonenzy-matic glycation and extractability of collagen in human atherosclerotic plaques. Atherosclerosis (1995) 116 63 75.
33. Fujimori E. Cross-linking and fluorescence changes of collagen by glycation and oxidation. Biochem. Biophys. Acta (1995) 998 105 110.
34. Wolff S.P., Dean R.T. Glucose autoxidation and protein modification. Biochem. J. (1987) 245 243 250.
35. Murakami K., Ito M., Yoshimo M. Xanthuronic acid inhibits metal ions-induced lipid peroxidation, NADP-isocitrate dehydrogenase from oxidative inactivation. J. Nutr. Sci. Vitaminol. (2001) 47 30 310.
36. Lieber C.S. Alcoholic liver disease: new insights in pathogenesis lead to new treatments. J. Hepatol. (2000) 32 113 128.
37. Tuma D.J., Thiele G.M., Xu D., Klassen L.W., Sorrel M.F. Acetaldehyde and malondialdehyde react together to generate distinct protein adducts in the liver during long-term ethanol administration. Hepatology (1996) 23 872 880.
38. Gouillon Z., Lucas D., Li J. et al. Inhibition of ethanol induced liver disease in the intragastric feeding rat model by chlormethiazole. Proc. Soc. Exp. Biol. Med. (2000) 224 302 308.
39. Yin M., Wheeler M.D., Kono H. et al. Essential role of tumor necrosis factor alpha in alcohol induced liver injury in mice. Gastroenterology (1999) 117 942 952.
40. Lieber C.S. Biochemical factors in alcoholic liver disease. Semin. Liv. Dis. (1993) 13 136 153.
41. Ueno T., Tamaki S., Sugawara H. et al. Significance of serum tissue inhibitor of metalloproteinases 1 in various liver diseases. J. Hepatol. (1996) 24 177 184.
42. Kurose I., Higuchi H., Kato S. et al. Oxidative stress on mitochondria and cell membrane of cultured rat hepatocytes and perfused liver exposed to ethanol. Gastroenterology (1997) 112 1331 1343.
43. Mary N.K., Achuthan C.R., Babu B.H., Padikkala J. In vitro antioxidant and antithrombotic activity of Hemidesmus indicus (L) R. Br. J. Ethnopharmacol. (2003) 87 187 191.